-
1
-
-
0030666222
-
Innate immunity: The virtues of a nonclonal system of recognition
-
Medzhitov, R., and A. Janeway, Jr. 1997. Innate immunity: the virtues of a nonclonal system of recognition. Cell. 91: 295-298.
-
(1997)
Cell
, vol.91
, pp. 295-298
-
-
Medzhitov, R.1
Janeway Jr., A.2
-
2
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov, R., P. Preston-Hurlburt, and C.A. Janeway. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388:394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway, C.A.3
-
3
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock, F.L., G. Hardiman, J.C. Timans, R. Kastelein, and F.J. Bazan. 1997. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA. 95:558-592.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 558-592
-
-
Rock, F.L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.4
Bazan, F.J.5
-
4
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre, B., E. Nicolas, L. Michaut, J.-M. Reichart, and J.A. Hoffmann. 1996. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 86:973-983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichart, J.-M.4
Hoffmann, J.A.5
-
5
-
-
0029009910
-
Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex
-
Greenfeder, S.A., P. Nunes, L. Kwee, M. Labow, R.A. Chizzonite, and G. Ju. 1995. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270:13757-13765.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13757-13765
-
-
Greenfeder, S.A.1
Nunes, P.2
Kwee, L.3
Labow, M.4
Chizzonite, R.A.5
Ju, G.6
-
6
-
-
0025774776
-
Drosophila Toll and IL-1 receptor
-
Gay, N.J., and F.J. Keith. 1991. Drosophila Toll and IL-1 receptor. Nature. 351:355-356.
-
(1991)
Nature
, vol.351
, pp. 355-356
-
-
Gay, N.J.1
Keith, F.J.2
-
7
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello, C.A. 1996. Biologic basis for interleukin-1 in disease. Blood. 87:2095-2147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
8
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio, M., J. Ni, P. Feng, and V.M. Dixit. 1997. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science. 278:1612-1615.
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
9
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche, H., W.J. Henzel, W. Shillinglaw, S. Li, and Z. Cao. 1997. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity. 7:837-847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
10
-
-
0029865142
-
IRAK: A kinase associated with the interleukin-1 receptor
-
Cao, Z., W. Henzel, and X. Gao. 1996. IRAK: a kinase associated with the interleukin-1 receptor. Science. 271:1128-1131.
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.2
Gao, X.3
-
11
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao, Z., J. Xiong, M. Takeuchi, T. Kurama, and D. Goeddel. 1996. TRAF6 is a signal transducer for interleukin-1. Nature. 383:443-446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.5
-
12
-
-
0031017618
-
MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
-
Malinin, N.L., M.P. Boldin, A.V. Kovalenko, and D. Wallach. 1997. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature. 385:540-544.
-
(1997)
Nature
, vol.385
, pp. 540-544
-
-
Malinin, N.L.1
Boldin, M.P.2
Kovalenko, A.V.3
Wallach, D.4
-
13
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
DiDonato, J.A., M. Hayakawa, D.M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature. 388:548-554.
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
DiDonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
14
-
-
0031586174
-
Identification and characterization of an Iκ-B kinase
-
Régnier, C.H., H.Y. Song, X. Gao, D.V. Goeddel, Z. Cao, and M. Rothe. 1997. Identification and characterization of an Iκ-B kinase. Cell. 90:373-383.
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Régnier, C.H.1
Song, H.Y.2
Gao, X.3
Goeddel, D.V.4
Cao, Z.5
Rothe, M.6
-
15
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio, F., H. Zhu, B.W. Murray, A. Shevcenko, B.L. Bennet, J.W. Li, D.U. Young, M. Barbosa, M. Mann, A. Manning, and A. Rao. 1997. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation. Science. 278:860-866.
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevcenko, A.4
Bennet, B.L.5
Li, J.W.6
Young, D.U.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
16
-
-
0030611595
-
IB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK
-
Woronicz, J.D., X. Gao, Z. Cao, M. Rothe, and D. Goeddel. 1997. IB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science. 278:866-869.
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
Rothe, M.4
Goeddel, D.5
-
17
-
-
0030613551
-
The IκB kinase complex contains two kinase subunits. IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
-
Zandi, E., D.M. Rothwarf, M. Delhase, M. Hayakawa, and M. Karin. 1997. The IκB kinase complex contains two kinase subunits. IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell. 91:243-252.
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
18
-
-
0031013545
-
Activation of SAPK/JNK by TNF receptor-1 through a noncytotoxic TRAF2-dependent pathway
-
Natoli, G., A. Costanzo, A. Ianni, D.J. Templeton, J.R. Woodgett, C. Balsano, and M. Levrero. 1997. Activation of SAPK/JNK by TNF receptor-1 through a noncytotoxic TRAF2-dependent pathway. Science. 275:200-203.
-
(1997)
Science
, vol.275
, pp. 200-203
-
-
Natoli, G.1
Costanzo, A.2
Ianni, A.3
Templeton, D.J.4
Woodgett, J.R.5
Balsano, C.6
Levrero, M.7
-
19
-
-
0028258896
-
Interleukin-13 induces the production of interleukin-1 receptor antagonist (IL-1ra) and the expression of the mRNA for the intracellular (keratinocyte) form of IL-1ra in human myelomonocytic cells
-
Muzio, M., F. Re, M. Sironi, N. Polentarutti, A. Minty, D. Caput, P. Ferrara, A. Mantovani, and F. Colotta. 1994. Interleukin-13 induces the production of interleukin-1 receptor antagonist (IL-1ra) and the expression of the mRNA for the intracellular (keratinocyte) form of IL-1ra in human myelomonocytic cells. Blood. 83:1738-1743.
-
(1994)
Blood
, vol.83
, pp. 1738-1743
-
-
Muzio, M.1
Re, F.2
Sironi, M.3
Polentarutti, N.4
Minty, A.5
Caput, D.6
Ferrara, P.7
Mantovani, A.8
Colotta, F.9
-
20
-
-
0026786698
-
Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila Toll protein are essential for IL-1R signal transduction
-
Heguy, A., C.T. Baldari, G. Macchia, J.L. Telford, and M. Melli. 1992. Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila Toll protein are essential for IL-1R signal transduction. J. Biol. Chem. 267:2605-2609.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 2605-2609
-
-
Heguy, A.1
Baldari, C.T.2
Macchia, G.3
Telford, J.L.4
Melli, M.5
-
21
-
-
0028124428
-
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor
-
Rothe, M., S.C. Wong, W.J. Henzel, and D.V. Goeddel. 1994. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor. Cell. 78:681-692.
-
(1994)
Cell
, vol.78
, pp. 681-692
-
-
Rothe, M.1
Wong, S.C.2
Henzel, W.J.3
Goeddel, D.V.4
-
22
-
-
0028978626
-
TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40
-
Rothe, M., V. Sarma, V.M. Dixit, and D.V. Goeddel. 1995. TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40. Science. 269:1424-1427.
-
(1995)
Science
, vol.269
, pp. 1424-1427
-
-
Rothe, M.1
Sarma, V.2
Dixit, V.M.3
Goeddel, D.V.4
-
23
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Derijard, B., M. Hibi, I.-H. Wu, T. Baret, B. Su, T. Deng, M. Karin, and R. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 76:1025-1037.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.-H.3
Baret, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.8
-
24
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
Kyriakis, J.M., P. Banerjee, E. Nikolakaki, T. Dai, E.A. Rubie, M.F. Ahmad, J. Avruch, and J.R. Woodgett. 1994. The stress-activated protein kinase subfamily of c-Jun kinases. Nature. 369:156-160.
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
Dai, T.4
Rubie, E.A.5
Ahmad, M.F.6
Avruch, J.7
Woodgett, J.R.8
-
25
-
-
0026799441
-
Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity
-
Adler, V., A. Polotskaya, F. Wagner, and A.S. Kraft. 1992. Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity. J. Biol. Chem. 267:17001-17005.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17001-17005
-
-
Adler, V.1
Polotskaya, A.2
Wagner, F.3
Kraft, A.S.4
-
26
-
-
0031048067
-
Tumor necrosis factor α-induced activation of c-Jun N-terminal kinase is mediated by TRAF2
-
Reinhard, C., B. Shamoon, V. Shyamala, and L.T. Williams. 1997. Tumor necrosis factor α-induced activation of c-Jun N-terminal kinase is mediated by TRAF2. EMBO (Eur. Mol. Biol. Organ.) J. 16:1080-1092.
-
(1997)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.16
, pp. 1080-1092
-
-
Reinhard, C.1
Shamoon, B.2
Shyamala, V.3
Williams, L.T.4
-
27
-
-
0030298294
-
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation presents cell death
-
Liu, Z., H. Hsu, D.V. Goeddel, and M. Karin. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation presents cell death. Cell. 87:565-576.
-
(1996)
Cell
, vol.87
, pp. 565-576
-
-
Liu, Z.1
Hsu, H.2
Goeddel, D.V.3
Karin, M.4
-
28
-
-
12644272789
-
Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of NF-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2
-
Song, H.J., C.H. Régnier, C.J. Kirschining, D.V. Goeddel, and M. Rothe. 1997. Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of NF-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. Proc. Natl. Acad. Sci. USA. 94:9792-9796.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9792-9796
-
-
Song, H.J.1
Régnier, C.H.2
Kirschining, C.J.3
Goeddel, D.V.4
Rothe, M.5
-
29
-
-
0030666194
-
TNF receptor-1 signaling downstream of TRAF2
-
Natoli, G., A. Costanzo, F. Moretti, M. Fulco, C. Balsano, and M. Levrero. 1997. TNF receptor-1 signaling downstream of TRAF2. J. Biol. Chem. 272:26079-26082.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26079-26082
-
-
Natoli, G.1
Costanzo, A.2
Moretti, F.3
Fulco, M.4
Balsano, C.5
Levrero, M.6
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