메뉴 건너뛰기




Volumn 187, Issue 12, 1998, Pages 2097-2101

The human toll signaling pathway: Divergence of nuclear factor κb and jnk/sapk activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)

Author keywords

C Jun NH2 terminal kinase stress activated protein kinase; Interleukin 1 receptor; Nuclear factor B; Toll

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; PROTEIN KINASE; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0032526861     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.12.2097     Document Type: Article
Times cited : (534)

References (29)
  • 1
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: The virtues of a nonclonal system of recognition
    • Medzhitov, R., and A. Janeway, Jr. 1997. Innate immunity: the virtues of a nonclonal system of recognition. Cell. 91: 295-298.
    • (1997) Cell , vol.91 , pp. 295-298
    • Medzhitov, R.1    Janeway Jr., A.2
  • 2
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov, R., P. Preston-Hurlburt, and C.A. Janeway. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388:394-397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway, C.A.3
  • 4
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre, B., E. Nicolas, L. Michaut, J.-M. Reichart, and J.A. Hoffmann. 1996. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 86:973-983.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichart, J.-M.4    Hoffmann, J.A.5
  • 5
    • 0029009910 scopus 로고
    • Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex
    • Greenfeder, S.A., P. Nunes, L. Kwee, M. Labow, R.A. Chizzonite, and G. Ju. 1995. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270:13757-13765.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13757-13765
    • Greenfeder, S.A.1    Nunes, P.2    Kwee, L.3    Labow, M.4    Chizzonite, R.A.5    Ju, G.6
  • 6
    • 0025774776 scopus 로고
    • Drosophila Toll and IL-1 receptor
    • Gay, N.J., and F.J. Keith. 1991. Drosophila Toll and IL-1 receptor. Nature. 351:355-356.
    • (1991) Nature , vol.351 , pp. 355-356
    • Gay, N.J.1    Keith, F.J.2
  • 7
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello, C.A. 1996. Biologic basis for interleukin-1 in disease. Blood. 87:2095-2147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 8
    • 0030694108 scopus 로고    scopus 로고
    • IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
    • Muzio, M., J. Ni, P. Feng, and V.M. Dixit. 1997. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science. 278:1612-1615.
    • (1997) Science , vol.278 , pp. 1612-1615
    • Muzio, M.1    Ni, J.2    Feng, P.3    Dixit, V.M.4
  • 9
    • 0031423761 scopus 로고    scopus 로고
    • MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
    • Wesche, H., W.J. Henzel, W. Shillinglaw, S. Li, and Z. Cao. 1997. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity. 7:837-847.
    • (1997) Immunity , vol.7 , pp. 837-847
    • Wesche, H.1    Henzel, W.J.2    Shillinglaw, W.3    Li, S.4    Cao, Z.5
  • 10
    • 0029865142 scopus 로고    scopus 로고
    • IRAK: A kinase associated with the interleukin-1 receptor
    • Cao, Z., W. Henzel, and X. Gao. 1996. IRAK: a kinase associated with the interleukin-1 receptor. Science. 271:1128-1131.
    • (1996) Science , vol.271 , pp. 1128-1131
    • Cao, Z.1    Henzel, W.2    Gao, X.3
  • 11
    • 0029761275 scopus 로고    scopus 로고
    • TRAF6 is a signal transducer for interleukin-1
    • Cao, Z., J. Xiong, M. Takeuchi, T. Kurama, and D. Goeddel. 1996. TRAF6 is a signal transducer for interleukin-1. Nature. 383:443-446.
    • (1996) Nature , vol.383 , pp. 443-446
    • Cao, Z.1    Xiong, J.2    Takeuchi, M.3    Kurama, T.4    Goeddel, D.5
  • 12
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
    • Malinin, N.L., M.P. Boldin, A.V. Kovalenko, and D. Wallach. 1997. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature. 385:540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 13
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato, J.A., M. Hayakawa, D.M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature. 388:548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 16
    • 0030611595 scopus 로고    scopus 로고
    • IB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK
    • Woronicz, J.D., X. Gao, Z. Cao, M. Rothe, and D. Goeddel. 1997. IB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science. 278:866-869.
    • (1997) Science , vol.278 , pp. 866-869
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.5
  • 17
    • 0030613551 scopus 로고    scopus 로고
    • The IκB kinase complex contains two kinase subunits. IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
    • Zandi, E., D.M. Rothwarf, M. Delhase, M. Hayakawa, and M. Karin. 1997. The IκB kinase complex contains two kinase subunits. IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell. 91:243-252.
    • (1997) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3    Hayakawa, M.4    Karin, M.5
  • 19
    • 0028258896 scopus 로고
    • Interleukin-13 induces the production of interleukin-1 receptor antagonist (IL-1ra) and the expression of the mRNA for the intracellular (keratinocyte) form of IL-1ra in human myelomonocytic cells
    • Muzio, M., F. Re, M. Sironi, N. Polentarutti, A. Minty, D. Caput, P. Ferrara, A. Mantovani, and F. Colotta. 1994. Interleukin-13 induces the production of interleukin-1 receptor antagonist (IL-1ra) and the expression of the mRNA for the intracellular (keratinocyte) form of IL-1ra in human myelomonocytic cells. Blood. 83:1738-1743.
    • (1994) Blood , vol.83 , pp. 1738-1743
    • Muzio, M.1    Re, F.2    Sironi, M.3    Polentarutti, N.4    Minty, A.5    Caput, D.6    Ferrara, P.7    Mantovani, A.8    Colotta, F.9
  • 20
    • 0026786698 scopus 로고
    • Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila Toll protein are essential for IL-1R signal transduction
    • Heguy, A., C.T. Baldari, G. Macchia, J.L. Telford, and M. Melli. 1992. Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila Toll protein are essential for IL-1R signal transduction. J. Biol. Chem. 267:2605-2609.
    • (1992) J. Biol. Chem. , vol.267 , pp. 2605-2609
    • Heguy, A.1    Baldari, C.T.2    Macchia, G.3    Telford, J.L.4    Melli, M.5
  • 21
    • 0028124428 scopus 로고
    • A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor
    • Rothe, M., S.C. Wong, W.J. Henzel, and D.V. Goeddel. 1994. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor. Cell. 78:681-692.
    • (1994) Cell , vol.78 , pp. 681-692
    • Rothe, M.1    Wong, S.C.2    Henzel, W.J.3    Goeddel, D.V.4
  • 22
    • 0028978626 scopus 로고
    • TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40
    • Rothe, M., V. Sarma, V.M. Dixit, and D.V. Goeddel. 1995. TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40. Science. 269:1424-1427.
    • (1995) Science , vol.269 , pp. 1424-1427
    • Rothe, M.1    Sarma, V.2    Dixit, V.M.3    Goeddel, D.V.4
  • 23
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B., M. Hibi, I.-H. Wu, T. Baret, B. Su, T. Deng, M. Karin, and R. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 76:1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.-H.3    Baret, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.8
  • 25
    • 0026799441 scopus 로고
    • Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity
    • Adler, V., A. Polotskaya, F. Wagner, and A.S. Kraft. 1992. Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity. J. Biol. Chem. 267:17001-17005.
    • (1992) J. Biol. Chem. , vol.267 , pp. 17001-17005
    • Adler, V.1    Polotskaya, A.2    Wagner, F.3    Kraft, A.S.4
  • 26
    • 0031048067 scopus 로고    scopus 로고
    • Tumor necrosis factor α-induced activation of c-Jun N-terminal kinase is mediated by TRAF2
    • Reinhard, C., B. Shamoon, V. Shyamala, and L.T. Williams. 1997. Tumor necrosis factor α-induced activation of c-Jun N-terminal kinase is mediated by TRAF2. EMBO (Eur. Mol. Biol. Organ.) J. 16:1080-1092.
    • (1997) EMBO (Eur. Mol. Biol. Organ.) J. , vol.16 , pp. 1080-1092
    • Reinhard, C.1    Shamoon, B.2    Shyamala, V.3    Williams, L.T.4
  • 27
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation presents cell death
    • Liu, Z., H. Hsu, D.V. Goeddel, and M. Karin. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation presents cell death. Cell. 87:565-576.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 28
    • 12644272789 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of NF-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2
    • Song, H.J., C.H. Régnier, C.J. Kirschining, D.V. Goeddel, and M. Rothe. 1997. Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of NF-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. Proc. Natl. Acad. Sci. USA. 94:9792-9796.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9792-9796
    • Song, H.J.1    Régnier, C.H.2    Kirschining, C.J.3    Goeddel, D.V.4    Rothe, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.