-
1
-
-
1842631153
-
Immunotherapeutic uses of CpG oligodeoxynucleotides
-
Klinman DM: Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat Rev Immunol 4: 249-258, 2004
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 249-258
-
-
Klinman, D.M.1
-
2
-
-
3142779901
-
Therapeutics targeting the innate immune system
-
Ulevitch RJ: Therapeutics targeting the innate immune system. Nat Rev Immunol 4: 512-520, 2004
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 512-520
-
-
Ulevitch, R.J.1
-
3
-
-
0842343142
-
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
-
Heikenwalder M, Polymenidou M, Junt T, Sigurdson C, Wagner H, Akira S, Zinkernagel R, Aguzzi A: Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. Nat Med 10: 187-192, 2004
-
(2004)
Nat Med
, vol.10
, pp. 187-192
-
-
Heikenwalder, M.1
Polymenidou, M.2
Junt, T.3
Sigurdson, C.4
Wagner, H.5
Akira, S.6
Zinkernagel, R.7
Aguzzi, A.8
-
4
-
-
0037307507
-
Bacterial CpG-DNA aggravates immune complex glomerulonephritis: Role of TLR9-mediated expression of chemokines and chemokine receptors
-
Anders HJ, Banas B, Linde Y, Weller L, Cohen CD, Kretzler M, Martin S, Vielhauer V, Schlondorff D, Grone HJ: Bacterial CpG-DNA aggravates immune complex glomerulonephritis: Role of TLR9-mediated expression of chemokines and chemokine receptors. J Am Soc Nephrol 14: 317-326, 2003
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 317-326
-
-
Anders, H.J.1
Banas, B.2
Linde, Y.3
Weller, L.4
Cohen, C.D.5
Kretzler, M.6
Martin, S.7
Vielhauer, V.8
Schlondorff, D.9
Grone, H.J.10
-
5
-
-
0032976985
-
Exacerbation of viral and autoimmune animal models for multiple sclerosis by bacterial DNA
-
Tsunoda I, Tolley ND, Theil DJ, Whitton JL, Kobayashi H, Fujinami RS: Exacerbation of viral and autoimmune animal models for multiple sclerosis by bacterial DNA. Brain Pathol 9: 481-493, 1999
-
(1999)
Brain Pathol
, vol.9
, pp. 481-493
-
-
Tsunoda, I.1
Tolley, N.D.2
Theil, D.J.3
Whitton, J.L.4
Kobayashi, H.5
Fujinami, R.S.6
-
6
-
-
0033758480
-
Unmethylated oligo-DNA containing CpG motifs aggravates collagen-induced arthritis in mice
-
Miyata M, Kobayashi H, Sasajima T, Sato Y, Kasukawa R: Unmethylated oligo-DNA containing CpG motifs aggravates collagen-induced arthritis in mice. Arthritis Rheum 43: 2578-2582, 2000
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2578-2582
-
-
Miyata, M.1
Kobayashi, H.2
Sasajima, T.3
Sato, Y.4
Kasukawa, R.5
-
7
-
-
1642396952
-
Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice
-
Anders HJ, Vielhauer V, Eis V, Linde Y, Kretzler M, Perez de Lema G, Strutz F, Bauer S, Rutz M, Wagner H, Grone HJ, Schlondorff D: Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice. FASEB J 18: 534-536, 2004
-
(2004)
FASEB J
, vol.18
, pp. 534-536
-
-
Anders, H.J.1
Vielhauer, V.2
Eis, V.3
Linde, Y.4
Kretzler, M.5
Perez de Lema, G.6
Strutz, F.7
Bauer, S.8
Rutz, M.9
Wagner, H.10
Grone, H.J.11
Schlondorff, D.12
-
8
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A: Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416: 603-607, 2002
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
9
-
-
85047693371
-
Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9
-
Means TK, Latz E, Hayashi F, Murali MR, Golenbock DT, Luster AD: Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. J Clin Invest 115: 407-417, 2005
-
(2005)
J Clin Invest
, vol.115
, pp. 407-417
-
-
Means, T.K.1
Latz, E.2
Hayashi, F.3
Murali, M.R.4
Golenbock, D.T.5
Luster, A.D.6
-
10
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, Klinman DM: CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374: 546-549, 1995
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
11
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird AP: CpG-rich islands and the function of DNA methylation. Nature 321: 209-213, 1986
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
12
-
-
7944219649
-
Immunotherapeutic utility of stimulatory and suppressive oligodeoxynucleotides
-
Ishii KJ, Gursel I, Gursel M, Klinman DM: Immunotherapeutic utility of stimulatory and suppressive oligodeoxynucleotides. Curr Opin Mol Ther 6: 166-174, 2004
-
(2004)
Curr Opin Mol Ther
, vol.6
, pp. 166-174
-
-
Ishii, K.J.1
Gursel, I.2
Gursel, M.3
Klinman, D.M.4
-
13
-
-
0142247168
-
DNA methylation and autoimmune disease
-
Richardson B: DNA methylation and autoimmune disease. Clin Immunol 109: 72-79, 2003
-
(2003)
Clin Immunol
, vol.109
, pp. 72-79
-
-
Richardson, B.1
-
14
-
-
0037378005
-
The molecular basis for the lack of immunostimulatory activity of vertebrate DNA
-
Stacey KJ, Young GR, Clark F, Sester DP, Roberts TL, Naik S, Sweet MJ, Hume DA: The molecular basis for the lack of immunostimulatory activity of vertebrate DNA. J Immunol 170: 3614-3620, 2003
-
(2003)
J Immunol
, vol.170
, pp. 3614-3620
-
-
Stacey, K.J.1
Young, G.R.2
Clark, F.3
Sester, D.P.4
Roberts, T.L.5
Naik, S.6
Sweet, M.J.7
Hume, D.A.8
-
15
-
-
0036107449
-
Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells
-
Stunz LL, Lenert P, Peckham D, Yi AK, Haxhinasto S, Chang M, Krieg AM, Ashman RF: Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells. Eur J Immunol 32: 1212-1222, 2002
-
(2002)
Eur J Immunol
, vol.32
, pp. 1212-1222
-
-
Stunz, L.L.1
Lenert, P.2
Peckham, D.3
Yi, A.K.4
Haxhinasto, S.5
Chang, M.6
Krieg, A.M.7
Ashman, R.F.8
-
16
-
-
0034856551
-
CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kappaB activation
-
Lenert P, Stunz L, Yi AK, Krieg AM, Ashman RF: CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kappaB activation. Antisense Nucleic Acid Drug Dev 11: 247-256, 2001
-
(2001)
Antisense Nucleic Acid Drug Dev
, vol.11
, pp. 247-256
-
-
Lenert, P.1
Stunz, L.2
Yi, A.K.3
Krieg, A.M.4
Ashman, R.F.5
-
17
-
-
0037637548
-
Influence of stimulatory and suppressive DNA motifs on host susceptibility to inflammatory arthritis
-
Zeuner RA, Verthelyi D, Gursel M, Ishii KJ, Klinman DM: Influence of stimulatory and suppressive DNA motifs on host susceptibility to inflammatory arthritis. Arthritis Rheum 48: 1701-1707, 2003
-
(2003)
Arthritis Rheum
, vol.48
, pp. 1701-1707
-
-
Zeuner, R.A.1
Verthelyi, D.2
Gursel, M.3
Ishii, K.J.4
Klinman, D.M.5
-
18
-
-
0021153603
-
Diffuse proliferative lupus nephritis: Identification of specific pathologic features affecting renal outcome
-
Austin HA 3rd, Muenz LR, Joyce KM, Antonovych TT, Balow JE: Diffuse proliferative lupus nephritis: Identification of specific pathologic features affecting renal outcome. Kidney Int 25: 689-695, 1984
-
(1984)
Kidney Int
, vol.25
, pp. 689-695
-
-
Austin III, H.A.1
Muenz, L.R.2
Joyce, K.M.3
Antonovych, T.T.4
Balow, J.E.5
-
19
-
-
0028012228
-
A monoclonal antibody (ER-HR3) against murine macrophages. IL Biochemical and functional aspects of the ER-HR3 antigen
-
de Jong JP, Leenen PJ, Voerman JS, van der Sluijs-Gelling AJ, Ploemacher RE: A monoclonal antibody (ER-HR3) against murine macrophages. IL Biochemical and functional aspects of the ER-HR3 antigen. Cell Tissue Res 275: 577-585, 1994
-
(1994)
Cell Tissue Res
, vol.275
, pp. 577-585
-
-
de Jong, J.P.1
Leenen, P.J.2
Voerman, J.S.3
van der Sluijs-Gelling, A.J.4
Ploemacher, R.E.5
-
20
-
-
20044385554
-
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
-
Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM: Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat Med 11: 138-145, 2005
-
(2005)
Nat Med
, vol.11
, pp. 138-145
-
-
Lang, K.S.1
Recher, M.2
Junt, T.3
Navarini, A.A.4
Harris, N.L.5
Freigang, S.6
Odermatt, B.7
Conrad, C.8
Ittner, L.M.9
Bauer, S.10
Luther, S.A.11
Uematsu, S.12
Akira, S.13
Hengartner, H.14
Zinkernagel, R.M.15
-
21
-
-
4344617762
-
Interferon-alpha in systemic lupus erythematosus
-
Crow MK, Kirou KA: Interferon-alpha in systemic lupus erythematosus. Curr Opin Rheumatol 16: 541-547, 2004
-
(2004)
Curr Opin Rheumatol
, vol.16
, pp. 541-547
-
-
Crow, M.K.1
Kirou, K.A.2
-
22
-
-
0032774579
-
Abnormal DNA methylation and deoxycytosine-deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis
-
Huck S, Deveaud E, Namane A, Zouali M: Abnormal DNA methylation and deoxycytosine-deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis. FASEB J 13: 1415-1422, 1999
-
(1999)
FASEB J
, vol.13
, pp. 1415-1422
-
-
Huck, S.1
Deveaud, E.2
Namane, A.3
Zouali, M.4
-
23
-
-
0037061423
-
Immunology: DNA drives autoimmunity
-
Vinuesa CG, Goodnow CC: Immunology: DNA drives autoimmunity. Nature 416: 595-598, 2002
-
(2002)
Nature
, vol.416
, pp. 595-598
-
-
Vinuesa, C.G.1
Goodnow, C.C.2
-
24
-
-
16244376480
-
Toll-like receptors, endogenous ligands, and systemic autoimmune disease
-
Rifkin IR, Leadbetter EA, Busconi L, Viglianti G, Marshak-Rothstein A: Toll-like receptors, endogenous ligands, and systemic autoimmune disease. Immunol Rev 204: 27-42, 2005
-
(2005)
Immunol Rev
, vol.204
, pp. 27-42
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Busconi, L.3
Viglianti, G.4
Marshak-Rothstein, A.5
-
25
-
-
2942679083
-
The immunobiology of the TLR9 subfamily
-
Wagner H: The immunobiology of the TLR9 subfamily. Trends Immunol 25: 381-386, 2004
-
(2004)
Trends Immunol
, vol.25
, pp. 381-386
-
-
Wagner, H.1
-
26
-
-
4644330955
-
Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner
-
Rutz M, Metzger J, Gellert T, Luppa P, Lipford GB, Wagner H, Bauer S: Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Eur J Immunol 34: 2541-2550, 2004
-
(2004)
Eur J Immunol
, vol.34
, pp. 2541-2550
-
-
Rutz, M.1
Metzger, J.2
Gellert, T.3
Luppa, P.4
Lipford, G.B.5
Wagner, H.6
Bauer, S.7
-
27
-
-
20244367698
-
Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon-alpha induction by CpG-A in plasmacytoid dendritic cells
-
Kerkmann M, Costa LT, Richter C, Rothenfusser S, Battiany J, Hornung V, Johnson J, Englert S, Ketterer T, Heckl W, Thalhammer S, Endres S, Hartmann G: Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon-alpha induction by CpG-A in plasmacytoid dendritic cells. J Biol Chem 280: 8086-8093, 2005
-
(2005)
J Biol Chem
, vol.280
, pp. 8086-8093
-
-
Kerkmann, M.1
Costa, L.T.2
Richter, C.3
Rothenfusser, S.4
Battiany, J.5
Hornung, V.6
Johnson, J.7
Englert, S.8
Ketterer, T.9
Heckl, W.10
Thalhammer, S.11
Endres, S.12
Hartmann, G.13
-
28
-
-
0035423557
-
An etiopathogenic role for the type IIFN system in SLE
-
Ronnblom L, Aim GV: An etiopathogenic role for the type IIFN system in SLE. Trends Immunol 22: 427-431, 2001
-
(2001)
Trends Immunol
, vol.22
, pp. 427-431
-
-
Ronnblom, L.1
Aim, G.V.2
-
29
-
-
2642528779
-
Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
-
Lovgren T, Eloranta ML, Bave U, Alm GV, Ronnblom L: Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 50: 1861-1982, 2004
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1861-1982
-
-
Lovgren, T.1
Eloranta, M.L.2
Bave, U.3
Alm, G.V.4
Ronnblom, L.5
-
30
-
-
5644227315
-
Suppressive oligodeoxynucleotides inhibit CpG-induced inflammation of the mouse lung
-
Yamada H, Ishii KJ, Klinman DM: Suppressive oligodeoxynucleotides inhibit CpG-induced inflammation of the mouse lung. Crit Care Med 32: 2045-2049, 2004
-
(2004)
Crit Care Med
, vol.32
, pp. 2045-2049
-
-
Yamada, H.1
Ishii, K.J.2
Klinman, D.M.3
-
31
-
-
0031910205
-
Hydroxychloroquine: Past, present, future
-
Petri M: Hydroxychloroquine: Past, present, future. Lupus 7: 65-67, 1998
-
(1998)
Lupus
, vol.7
, pp. 65-67
-
-
Petri, M.1
|