CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

EMBO Journal

Volumn 17, Issue 21, 1998, Pages 6230-6240

  Häcker, Hans ^a   Mischak, Harald ^a,b   Miethke, Thomas ^a   Liptay, Susanne ^c   Schmid, Roland ^c   Sparwasser, Tim ^a   Heeg, Klaus ^a   Lipford, Grayson B ^a   Wagner, Hermann ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c Franz Volhard Klinik   (Germany)

Author keywords

Antigen presenting cell; CpG DNA; p38 MAP kinase; SAPK

Indexed keywords

BAFILOMYCIN; CHLOROQUINE; INTERLEUKIN 12; PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CPG ISLAND; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; MOUSE; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; ANTIGEN-PRESENTING CELLS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CHLOROQUINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOKINES; DNA METHYLATION; DNA, BACTERIAL; ENDOCYTOSIS; ENDOSOMES; ENZYME ACTIVATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; OLIGORIBONUCLEOTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); MURINAE; PROKARYOTA;

EID: 0032476602     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.21.6230     Document Type: Article

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