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Volumn 36, Issue 7, 2006, Pages 1951-1962

Higher-order CpG-DNA stimulation reveals distinct activation requirements for marginal zone and follicular B cells in lupus mice

Author keywords

Autoimmunity; B lymphocytes; CpG; Interferons; Lupus

Indexed keywords

B LYMPHOCYTE RECEPTOR; CPG OLIGODEOXYNUCLEOTIDE; DNA; INTERFERON; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 1; INTERLEUKIN 12P40; INTERLEUKIN 6; LIGAND; TOLL LIKE RECEPTOR 9;

EID: 33746238512     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200535734     Document Type: Article
Times cited : (19)

References (46)
  • 1
    • 0023204355 scopus 로고
    • Systemic autoimmune disease arises from polyclonal B cell activation
    • Klinman, D. M. and Steinberg, A. D., Systemic autoimmune disease arises from polyclonal B cell activation. J. Exp. Med. 1987. 165: 1755-1760.
    • (1987) J. Exp. Med. , vol.165 , pp. 1755-1760
    • Klinman, D.M.1    Steinberg, A.D.2
  • 2
    • 0035555161 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: An autoimmune disease of B cell hyperactivity
    • Lipsky, P. E., Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity. Nat. Immunol. 2001. 2: 764-766.
    • (2001) Nat. Immunol. , vol.2 , pp. 764-766
    • Lipsky, P.E.1
  • 3
    • 0027477318 scopus 로고
    • Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus
    • Mohan, C., Adams, S., Stanik, V. and Datta, S. K., Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus. J. Exp. Med. 1993. 177: 1367-1381.
    • (1993) J. Exp. Med. , vol.177 , pp. 1367-1381
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 4
    • 0031825552 scopus 로고    scopus 로고
    • Systemic exposure to irradiated apoptotic cells induces autoantibody production
    • Mevorach, D., Zhou, J. L., Song, X. and Elkon, K. B., Systemic exposure to irradiated apoptotic cells induces autoantibody production. J. Exp. Med. 1998. 188: 387-392.
    • (1998) J. Exp. Med. , vol.188 , pp. 387-392
    • Mevorach, D.1    Zhou, J.L.2    Song, X.3    Elkon, K.B.4
  • 5
    • 0024518559 scopus 로고
    • Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology
    • Tan, E. M., Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. Adv. Immunol. 1989. 44: 93-151.
    • (1989) Adv. Immunol. , vol.44 , pp. 93-151
    • Tan, E.M.1
  • 6
    • 0030755510 scopus 로고    scopus 로고
    • B lymphocytes as autoantigen-presenting cells in the amplification of autoimmunity
    • Roth, R., Gee, R. J. and Mamula, M. J., B lymphocytes as autoantigen-presenting cells in the amplification of autoimmunity. Ann. NY Acad. Sci. 1997. 815: 88-104.
    • (1997) Ann. NY Acad. Sci. , vol.815 , pp. 88-104
    • Roth, R.1    Gee, R.J.2    Mamula, M.J.3
  • 7
    • 0031882091 scopus 로고    scopus 로고
    • A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice
    • Chan, O. and Shlomchik, M. J., A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/ lpr mice. J. Immunol. 1998. 160: 51-59.
    • (1998) J. Immunol. , vol.160 , pp. 51-59
    • Chan, O.1    Shlomchik, M.J.2
  • 8
    • 15244349648 scopus 로고    scopus 로고
    • TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production
    • Lenert, P., Brummel, R., Field, E. H. and Ashman, R. F., TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production. J. Clin. Immunol. 2005. 25: 29-40.
    • (2005) J. Clin. Immunol. , vol.25 , pp. 29-40
    • Lenert, P.1    Brummel, R.2    Field, E.H.3    Ashman, R.F.4
  • 11
    • 0028962115 scopus 로고
    • Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus
    • Llorente, L., Zou, W., Levy, Y., Rachaud-Patin, Y., Wijdenes, J., Alcocer-Varela, J., Morel-Fourrier, B. et al., Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus. J. Exp. Med. 1995. 181: 839-844.
    • (1995) J. Exp. Med. , vol.181 , pp. 839-844
    • Llorente, L.1    Zou, W.2    Levy, Y.3    Rachaud-Patin, Y.4    Wijdenes, J.5    Alcocer-Varela, J.6    Morel-Fourrier, B.7
  • 12
    • 4644241216 scopus 로고    scopus 로고
    • CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10
    • He, B., Qiao, X. and Cerutti, A., CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10. J. Immunol. 2004. 173: 4479-4491.
    • (2004) J. Immunol. , vol.173 , pp. 4479-4491
    • He, B.1    Qiao, X.2    Cerutti, A.3
  • 13
    • 0028824955 scopus 로고
    • CpG DNA: A pathogenic factor in systemic lupus erythematosus
    • Krieg, A. M., CpG DNA: A pathogenic factor in systemic lupus erythematosus. J. Clin. Immunol. 1995. 15: 284-292.
    • (1995) J. Clin. Immunol. , vol.15 , pp. 284-292
    • Krieg, A.M.1
  • 15
    • 16244423314 scopus 로고    scopus 로고
    • Inhibitory oligodeoxynucleotides: Therapeutic promise for systemic autoimmune diseases?
    • Lenert, P., Inhibitory oligodeoxynucleotides: Therapeutic promise for systemic autoimmune diseases? Clin. Exp. Immunol. 2005. 140: 1-10.
    • (2005) Clin. Exp. Immunol. , vol.140 , pp. 1-10
    • Lenert, P.1
  • 17
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products and cytokines
    • Zarember, K. A. and Godowski, P. J., Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products and cytokines. J. Immunol. 2002. 168: 554-561.
    • (2002) J. Immunol. , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 18
    • 0026006734 scopus 로고
    • Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA
    • Messina, J. P., Gilkeson, G. S. and Pisetsky, D. S., Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J. Immunol. 1991. 147: 1759-1764.
    • (1991) J. Immunol. , vol.147 , pp. 1759-1764
    • Messina, J.P.1    Gilkeson, G.S.2    Pisetsky, D.S.3
  • 20
    • 0042329609 scopus 로고    scopus 로고
    • The central role of dendritic cells and interferon-alpha in SLE
    • Pascual, V., Banchereau, J. and Palucka, A. K., The central role of dendritic cells and interferon-alpha in SLE. Curr. Opin. Rheumatol. 2003. 15: 548-556.
    • (2003) Curr. Opin. Rheumatol. , vol.15 , pp. 548-556
    • Pascual, V.1    Banchereau, J.2    Palucka, A.K.3
  • 21
    • 0033485756 scopus 로고    scopus 로고
    • Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-α inducer in systemic lupus erythematosus
    • Vallin, H., Perers, A., Alm, G. V. and Ronnblom, L., Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-α inducer in systemic lupus erythematosus. J. Immunol. 1999. 163: 6306-6313.
    • (1999) J. Immunol. , vol.163 , pp. 6306-6313
    • Vallin, H.1    Perers, A.2    Alm, G.V.3    Ronnblom, L.4
  • 22
    • 0025057503 scopus 로고
    • Possible induction of systemic lupus erythematosus by interferon-a treatment in a patient with a malignant carcinoid tumor
    • Ronnblom, L. E., Alm, G. V. and Oberg, K. E., Possible induction of systemic lupus erythematosus by interferon-a treatment in a patient with a malignant carcinoid tumor. J. Intern. Med. 1990. 227: 207-210.
    • (1990) J. Intern. Med. , vol.227 , pp. 207-210
    • Ronnblom, L.E.1    Alm, G.V.2    Oberg, K.E.3
  • 25
    • 13544254614 scopus 로고    scopus 로고
    • Activation of marginal zone B cells from lupus mice with class A(D) CpG-oligodeoxynucleotides
    • Brummel, R. and Lenert, P., Activation of marginal zone B cells from lupus mice with class A(D) CpG-oligodeoxynucleotides. J. Immunol. 2005. 174: 2429-2434.
    • (2005) J. Immunol. , vol.174 , pp. 2429-2434
    • Brummel, R.1    Lenert, P.2
  • 26
    • 0034933019 scopus 로고    scopus 로고
    • Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmocytoid dendritic cells
    • Krug, A., Rothenfusser, S., Hornung, V., Jahrsdorfer, B., Blackwell, S., Ballas, Z. K., Endres, S. et al., Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmocytoid dendritic cells. Eur. J. Immunol. 2001. 31: 2154-2163.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 2154-2163
    • Krug, A.1    Rothenfusser, S.2    Hornung, V.3    Jahrsdorfer, B.4    Blackwell, S.5    Ballas, Z.K.6    Endres, S.7
  • 27
    • 0035865054 scopus 로고    scopus 로고
    • Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs
    • Verthelyi, D., Ishii, K. J., Gursel, M., Takeshita, F. and Klinman, D. M., Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs. J. Immunol. 2001. 166: 2372-2377.
    • (2001) J. Immunol. , vol.166 , pp. 2372-2377
    • Verthelyi, D.1    Ishii, K.J.2    Gursel, M.3    Takeshita, F.4    Klinman, D.M.5
  • 28
    • 20244367698 scopus 로고    scopus 로고
    • Spontaneous formation of nucleic acid-based nanoparticules is responsible for high interferon-α induction by CpG-A in plasmocytoid dendritic cells
    • Kerkmann, M., Costa, L. T., Richter, C., Rothenfusser, S., Battiany, J., Hornung, V., Johnson, J. et al., Spontaneous formation of nucleic acid-based nanoparticules is responsible for high interferon-α induction by CpG-A in plasmocytoid dendritic cells. J. Biol. Chem. 2005. 280: 8086-8093.
    • (2005) J. Biol. Chem. , vol.280 , pp. 8086-8093
    • Kerkmann, M.1    Costa, L.T.2    Richter, C.3    Rothenfusser, S.4    Battiany, J.5    Hornung, V.6    Johnson, J.7
  • 29
    • 0038142387 scopus 로고    scopus 로고
    • A role for Toll-like receptors in acquired immunity: Up-regulation of TLR9 by BCR triggering in naïve B cells and constitutive expression in memory B cells
    • Bernasconi, N. L., Onai, N. and Lanzavecchia, A., A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naïve B cells and constitutive expression in memory B cells. Blood 2003. 101: 4500-4504.
    • (2003) Blood , vol.101 , pp. 4500-4504
    • Bernasconi, N.L.1    Onai, N.2    Lanzavecchia, A.3
  • 30
    • 0030240062 scopus 로고    scopus 로고
    • Macrophages ingest and are activated by bacterial DNA
    • Stacey, K. J., Sweet, M. J. and Hume, D. A., Macrophages ingest and are activated by bacterial DNA. J. Immunol. 1996. 157: 2116-2122.
    • (1996) J. Immunol. , vol.157 , pp. 2116-2122
    • Stacey, K.J.1    Sweet, M.J.2    Hume, D.A.3
  • 31
    • 0031867535 scopus 로고    scopus 로고
    • Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
    • Sparwasser, T., Koch, E. S., Vabulas, R. M., Heeg, K., Lipford, G. B., Ellwart, J. W. and Wagner, H., Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol. 1998. 28: 2045-2054.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2045-2054
    • Sparwasser, T.1    Koch, E.S.2    Vabulas, R.M.3    Heeg, K.4    Lipford, G.B.5    Ellwart, J.W.6    Wagner, H.7
  • 32
    • 11144353781 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help
    • Poeck, H., Wagner, M., Battiany, J., Rothenfusser, S., Wellisch, D., Hornung, V., Jahrsdorfer, B. et al., Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help. Blood 2004. 103: 3058-3064.
    • (2004) Blood , vol.103 , pp. 3058-3064
    • Poeck, H.1    Wagner, M.2    Battiany, J.3    Rothenfusser, S.4    Wellisch, D.5    Hornung, V.6    Jahrsdorfer, B.7
  • 33
    • 0029670726 scopus 로고    scopus 로고
    • IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides
    • YI, A. K., Chace, J. H., Cowdery, J. S. and Krieg, A. M., IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides. J. Immunol. 1996. 156: 558-564.
    • (1996) J. Immunol. , vol.156 , pp. 558-564
    • YI, A.K.1    Chace, J.H.2    Cowdery, J.S.3    Krieg, A.M.4
  • 34
    • 0036754302 scopus 로고    scopus 로고
    • Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses
    • Balazs, M., Martin, F., Zhou, T. and Kearney, J. F., Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 2002. 17: 341-352.
    • (2002) Immunity , vol.17 , pp. 341-352
    • Balazs, M.1    Martin, F.2    Zhou, T.3    Kearney, J.F.4
  • 35
    • 0345447639 scopus 로고    scopus 로고
    • Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice
    • Spies, B., Hochrein, H., Vabulas, M., Huster, K., Busch, D. H., Schmitz, F., Heit, A. et al., Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice. J. Immunol. 2003. 171: 5908-5912.
    • (2003) J. Immunol. , vol.171 , pp. 5908-5912
    • Spies, B.1    Hochrein, H.2    Vabulas, M.3    Huster, K.4    Busch, D.H.5    Schmitz, F.6    Heit, A.7
  • 36
    • 0032526607 scopus 로고    scopus 로고
    • CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry
    • Yi, A. K., Chang, M., Peckham, D. W., Krieg, A. M. and Ashman, R. F., CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry. J. Immunol. 1998. 160: 5898-5906.
    • (1998) J. Immunol. , vol.160 , pp. 5898-5906
    • Yi, A.K.1    Chang, M.2    Peckham, D.W.3    Krieg, A.M.4    Ashman, R.F.5
  • 37
    • 0037378005 scopus 로고    scopus 로고
    • The molecular basis for the lack of immunostimulatory activity of vertebrate DNA
    • Stacey, K., Young, G. R., Clark, F., Sester, D. P., Roberts, T. L., Naik, S., Sweet, M. J. et al., The molecular basis for the lack of immunostimulatory activity of vertebrate DNA. J. Immunol. 2003. 170: 3614-3620.
    • (2003) J. Immunol. , vol.170 , pp. 3614-3620
    • Stacey, K.1    Young, G.R.2    Clark, F.3    Sester, D.P.4    Roberts, T.L.5    Naik, S.6    Sweet, M.J.7
  • 38
    • 18644383289 scopus 로고    scopus 로고
    • Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and independent pathways
    • Yasuda, K., Yu, P., Kirschning, C. J., Schlatter, B., Schmitz, F., Heit, A., Bauer, S., Hochrein, H. et al., Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and independent pathways. J. Immunol. 2005. 174: 6129-6136.
    • (2005) J. Immunol. , vol.174 , pp. 6129-6136
    • Yasuda, K.1    Yu, P.2    Kirschning, C.J.3    Schlatter, B.4    Schmitz, F.5    Heit, A.6    Bauer, S.7    Hochrein, H.8
  • 40
    • 4644330955 scopus 로고    scopus 로고
    • Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence-and pH-dependent manner
    • Rutz, M., Metzger, J., Gellert, T., Luppa, P., Lipford, G. B., Wagner, H. and Bauer, S., Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence-and pH-dependent manner. Eur. J. Immunol. 2004. 34: 2541-2550.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2541-2550
    • Rutz, M.1    Metzger, J.2    Gellert, T.3    Luppa, P.4    Lipford, G.B.5    Wagner, H.6    Bauer, S.7
  • 41
    • 0020052580 scopus 로고
    • DNA isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content
    • Sano, H. and Morimoto, C., DNA isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content. J. Immunol. 1982. 128: 1341-1345.
    • (1982) J. Immunol. , vol.128 , pp. 1341-1345
    • Sano, H.1    Morimoto, C.2
  • 42
    • 27744444832 scopus 로고    scopus 로고
    • RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
    • Lau, C. M., Broughton, C., Tabor, A. S., Akira, S., Flavell, R. A., Mamula, M. J., Christensen, S. R. et al., RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J. Exp. Med. 2005. 202: 1171-1177.
    • (2005) J. Exp. Med. , vol.202 , pp. 1171-1177
    • Lau, C.M.1    Broughton, C.2    Tabor, A.S.3    Akira, S.4    Flavell, R.A.5    Mamula, M.J.6    Christensen, S.R.7
  • 43
    • 28544449709 scopus 로고    scopus 로고
    • Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
    • Vollmer, J., Tluk, S., Schmitz, C., Hamm, S., Jurk, M., Forsbach, A., Akira, S. et al., Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8. J. Exp. Med. 2005. 202: 1575-1585.
    • (2005) J. Exp. Med. , vol.202 , pp. 1575-1585
    • Vollmer, J.1    Tluk, S.2    Schmitz, C.3    Hamm, S.4    Jurk, M.5    Forsbach, A.6    Akira, S.7
  • 45
    • 28244458932 scopus 로고    scopus 로고
    • A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene
    • Guo, Z., Garg, S., Hill, K. M., Jayashankar, L., Mooney, M.R., Hoelscher, M., Katz, J. M. et al., A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene. J. Immunol. 2005. 175: 7407-7418.
    • (2005) J. Immunol. , vol.175 , pp. 7407-7418
    • Guo, Z.1    Garg, S.2    Hill, K.M.3    Jayashankar, L.4    Mooney, M.R.5    Hoelscher, M.6    Katz, J.M.7
  • 46
    • 0036107449 scopus 로고    scopus 로고
    • Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells
    • Stunz, L. L., Lenert, P., Peckham, D., Yi, A. K., Haxhinasto, S., Chang, M., Krieg, A. M. et al., Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells. Eur. J. Immunol. 2002. 32: 1212-1222.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1212-1222
    • Stunz, L.L.1    Lenert, P.2    Peckham, D.3    Yi, A.K.4    Haxhinasto, S.5    Chang, M.6    Krieg, A.M.7


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