메뉴 건너뛰기




Volumn 665, Issue , 2009, Pages 47-59

The biology of FoxP3: AKey player in immune suppression during infections, autoimmune diseases and cancer

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE 7; ISOPROTEIN; LEUCINE ZIPPER PROTEIN; PROLINE; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR NFAT; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN;

EID: 77952472919     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-1599-3_4     Document Type: Article
Times cited : (42)

References (107)
  • 1
    • 0037385330 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1038/ni904
    • Fontenot JD. Gavin MA. RudenskyAY. Foxp3 programs the development and function of CD4+CD25+ regulatory T-cells. Nat Immunol2003; 4(4) :330-336. (Pubitemid 36432314)
    • (2003) Nature Immunology , vol.4 , Issue.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 2
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • DOI 10.1126/science.1079490
    • Hori S. Nomura T. Sakaguchi S. Control of regulatory T-cell development by the transcription factor Foxp3. Science 2003; 299(5609) :1057-1061. (Pubitemid 36222930)
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 5
    • 19344374571 scopus 로고    scopus 로고
    • HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
    • Oswald-Richter K, Grill SM, Shariat N, et al. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. PLoS Bioi 2004; 2(7) :EI98.
    • (2004) PLoS Bioi , vol.2 , Issue.7
    • Oswald-Richter, K.1    Grill, S.M.2    Shariat, N.3
  • 6
    • 47049125575 scopus 로고    scopus 로고
    • Forced overexpression of either of the two common human Foxp3 isoforms can induce regulatory T-cells from CD4(+)CD25(-) cells
    • Aarcs-RiemensT. Emmelor ME. Verdonck LF, et al. Forced overexpression of either of the two common human Foxp3 isoforms can induce regulatory T-cells from CD4(+)CD25(-) cells. EurJ Immunol 2008; 38(5) :1381-1390.
    • (2008) EurJ Immunol , vol.38 , Issue.5 , pp. 1381-1390
    • Aarcs-Riemens, T.1    Emmelor, M.E.2    Verdonck, L.F.3
  • 7
    • 0037383757 scopus 로고    scopus 로고
    • Twenty-firsr cenmry Foxp3
    • O'Garra A, Vieira P. Twenty-firsr cenmry Foxp3. Nat Immunol2003; 4(4) :304-306.
    • (2003) Nat Immunol , vol.4 , Issue.4 , pp. 304-306
    • O'Garra, A.1    Vieira, P.2
  • 8
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • DOI 10.1084/jem.188.2.287
    • Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T-cells suppress polyclonal T-cell activation in viero by inhibiting interleukin 2 producelon.J Exp Med 1998; 188(2):287-296. (Pubitemid 28357757)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.2 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 9
    • 33750447327 scopus 로고    scopus 로고
    • + immunoregulatory T cells
    • DOI 10.1111/j.1440-1711.2006.01471.x
    • Zwar TD, van Driel IR, Gleeson PA. Guarding the immune system: Suppression of autoimmunity by CD4+CD25+ immunoregulatory T-cells. Immunology and Cell Biology 2006; 84(6) :487-501. (Pubitemid 44657021)
    • (2006) Immunology and Cell Biology , vol.84 , Issue.6 , pp. 487-501
    • Zwar, T.D.1    Van Driel, I.R.2    Gleeson, P.A.3
  • 10
    • 36249024247 scopus 로고    scopus 로고
    • Regulatory T-cells-A brief history and perspective
    • Sakaguchi S, Wing K. Miyara M. Regulatory T-cells-a brief history and perspective. EurJ Immunol 2007; 37(Suppll):SI16-123.
    • (2007) EurJ Immunol , vol.37 , Issue.SUPPL. 1
    • Sakaguchi, S.1    Wing, K.2    Miyara, M.3
  • 11
    • 42149169184 scopus 로고    scopus 로고
    • Mechanisms of regulatory T-cell suppression - A diverse arsenal for a moving target
    • DOI 10.1111/j.1365-2567.2008.02813.x
    • Sojka DK, Huang YH, Fowell DJ. Mechanisms of regulatory T-cell suppression-a diverse arsenal for a moving target. Immunology 2008; 124(1):13-22. (Pubitemid 351537583)
    • (2008) Immunology , vol.124 , Issue.1 , pp. 13-22
    • Sojka, D.K.1    Huang, Y.-H.2    Fowell, D.J.3
  • 12
    • 0036961493 scopus 로고    scopus 로고
    • Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: A model of immune dysregulation
    • DOI 10.1097/00130832-200212000-00002
    • Torgerson TR, Ochs HD. Immune dysregulanon, polyeadocrinopathy, enteropathy, X-linked syndrome: A model of immune dysregulation. Curr Opin Allergy Clin Immunol 2002; 2(6) :481-487. (Pubitemid 36105810)
    • (2002) Current Opinion in Allergy and Clinical Immunology , vol.2 , Issue.6 , pp. 481-487
    • Torgerson, T.R.1    Ochs, H.D.2
  • 13
    • 37149018400 scopus 로고    scopus 로고
    • FOXP3 actively represses eranscription by recruiting the HAT/HDAC complex
    • Li B. Greene MI. FOXP3 actively represses eranscription by recruiting the HAT/HDAC complex. Cell Cycle 2007; 6(12) :1432-1436.
    • (2007) Cell Cycle , vol.6 , Issue.12 , pp. 1432-1436
    • Li, B.1    Greene, M.I.2
  • 15
    • 33947576560 scopus 로고    scopus 로고
    • Opinion: FOXP3 modifies the phenotypic and functional properties of regulatory T cells
    • DOI 10.1038/nri2061, PII NRI2061
    • Campbell DJ. Ziegler SF. FOXP3 modifies the phenotypic and functional properties of regulatory T-cells. Nat Rev Immunol 2007; 7(4):305-310. (Pubitemid 46480960)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.4 , pp. 305-310
    • Campbell, D.J.1    Ziegler, S.F.2
  • 16
    • 0038434099 scopus 로고    scopus 로고
    • Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
    • DOI 10.1097/00002281-200307000-00010
    • Gambineri E, Torgerson TR, Ochs HD. Immune dysregularion, polyendocrinopathy, enteropathy and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3. A critical regulator ofT-cell homeostasis. Curr Opin Rheumatol 2003; 15(4):430-435. (Pubitemid 36774255)
    • (2003) Current Opinion in Rheumatology , vol.15 , Issue.4 , pp. 430-435
    • Gambineri, E.1    Torgerson, T.R.2    Ochs, H.D.3
  • 17
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • DOI 10.1038/ni1455, PII NI1455
    • Zheng Y. Rudensky AY. Foxp3 in control of the regulatory T'-cell lineage. Nat Immunol 2007; 8(5):457-462. (Pubitemid 46605910)
    • (2007) Nature Immunology , vol.8 , Issue.5 , pp. 457-462
    • Zheng, Y.1    Rudensky, A.Y.2
  • 20
    • 17044393922 scopus 로고    scopus 로고
    • Foxp3 interacts with nuclear factor of activated T-cells and NF-kappa B to repress cyeokine gene expression and effector functions of T helper cells
    • Bertelli E. Damange M. Oukka M. Foxp3 interacts with nuclear factor of activated T-cells and NF-kappa B to repress cyeokine gene expression and effector functions of T helper cells. Proc Nad Acad Sci USA 2005; 102(14) :5138-5143
    • (2005) Proc Nad Acad Sci USA , vol.102 , Issue.14 , pp. 5138-5143
    • Bertelli, E.1    Damange, M.2    Oukka, M.3
  • 22
    • 33847220736 scopus 로고    scopus 로고
    • Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T-cells
    • Zheng Y. Josefowicz SZ. Kas A, et al. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T-cells. Nature 2007; 445(7130):936-940.
    • (2007) Nature , vol.445 , Issue.7130 , pp. 936-940
    • Zheng, Y.1    Josefowicz, S.Z.2    Kas, A.3
  • 25
    • 33846016948 scopus 로고    scopus 로고
    • Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation
    • DOI 10.1074/jbc.M608848200
    • Chen C, RowellEA, Thomas RM, et al. Transcriptional regulation by Foxp3 is associatedwith direct promoter occupancy and modulation of histone acetylation.J Bioi Chern 2006; 281(48) :36828-36834. (Pubitemid 46042151)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.48 , pp. 36828-36834
    • Chen, C.1    Rowell, E.A.2    Thomas, R.M.3    Hancock, W.W.4    Wells, A.D.5
  • 26
    • 15244354286 scopus 로고    scopus 로고
    • Regulatory T cell lineage specification by the forkhead transcription factor Foxp3
    • DOI 10.1016/j.immuni.2005.01.016
    • Fontenot JD, RasmussenJP. Williams LM, et al. Regulatory T-cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005; 22(3) :329-341. (Pubitemid 40387475)
    • (2005) Immunity , vol.22 , Issue.3 , pp. 329-341
    • Fontenot, J.D.1    Rasmussen, J.P.2    Williams, L.M.3    Dooley, J.L.4    Farr, A.G.5    Rudensky, A.Y.6
  • 27
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: Of mice and men
    • Ziegler SF. FOXP3: Of mice and men. Annu Rev Immunol 2006; 24:209-226.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 29
    • 33748751458 scopus 로고    scopus 로고
    • + T-cell activation
    • DOI 10.1111/j.1365-2567.2006.02425.x
    • Smith EL, Finney HM, Nesbitt AM, et al. Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation. Immunology 2006; 119(2) :203-211. (Pubitemid 44401639)
    • (2006) Immunology , vol.119 , Issue.2 , pp. 203-211
    • Smith, E.L.1    Finney, H.M.2    Nesbitt, A.M.3    Ramsdell, F.4    Robinson, M.K.5
  • 30
    • 44449131480 scopus 로고    scopus 로고
    • Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3
    • Du J, Huang C, Zhou B, et al. Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3. J Immunol 2008; 180(7):4785-4792.
    • (2008) J Immunol , vol.180 , Issue.7 , pp. 4785-4792
    • Du, J.1    Huang, C.2    Zhou, B.3
  • 31
  • 32
    • 33748460087 scopus 로고    scopus 로고
    • Foxp3-dependent and -independenc molecules specific for CD 25+CD4+ natu ral regulatory T-cells revealed by DNA microarray analysis
    • Sugimoto N, Oida T, Hirota K, et al. Foxp3-dependent and -independenc molecules specific for CD 25+CD4+ natu ral regulatory T-cells revealed by DNA microarray analysis. Inr Immunol 2006; 18(8):1l97-1209.
    • (2006) Inr Immunol , vol.18 , Issue.8
    • Sugimoto, N.1    Oida, T.2    Hirota, K.3
  • 37
    • 35448930435 scopus 로고    scopus 로고
    • - T cells by T-cell receptor stimulation is transforming growth factor-β-dependent but does not confer a regulatory phenotype
    • DOI 10.1182/blood-2007-06-094656
    • Tran DQ, Ramsey H, Shevach EM. Induction of FOXP3 expression in naive human CD4+FOXP3 T-cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype Blood 2007; 1l0(8):2983-2990. (Pubitemid 350006952)
    • (2007) Blood , vol.110 , Issue.8 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 38
    • 44849133287 scopus 로고    scopus 로고
    • The critical contribution of TGF-beta co the induction of Foxp3 expression and regulacoryT-cell function
    • Shevach EM, Tran DQ, Davidson TS, et al. The critical contribution of TGF-beta co the induction of Foxp3 expression and regulacoryT-cell function. Eur J Immunol2008: 38(4) :915-917.
    • Eur J Immunol2008 , vol.38 , Issue.4 , pp. 915-917
    • Shevach, E.M.1    Tran, D.Q.2    Davidson, T.S.3
  • 41
    • 44849118564 scopus 로고    scopus 로고
    • Rethinking the molecular definition of regulato ry T-cells
    • Hori S. Rethinking the molecular definition of regulato ry T-cells. Eur J Immunol 2008; 38(4) :928-930.
    • (2008) Eur J Immunol , vol.38 , Issue.4 , pp. 928-930
    • Hori, S.1
  • 42
    • 34548733134 scopus 로고    scopus 로고
    • A kinetic and dynamic analysis of Foxp3 induced in T-cells by TGF-beta
    • following 1390
    • Selvaraj RK, Geiger TL. A kinetic and dynamic analysis of Foxp3 induced in T-cells by TGF-beta. J Immunol 2007: 179(2):1l p following 1390.
    • (2007) J Immunol , vol.179 , Issue.2
    • Selvaraj, R.K.1    Geiger, T.L.2
  • 44
    • 33748448717 scopus 로고    scopus 로고
    • Transforming Growth Factor-β Controls Development, Homeostasis, and Tolerance of T Cells by Regulatory T Cell-Dependent and -Independent Mechanisms
    • DOI 10.1016/j.immuni.2006.07.011, PII S1074761306003876
    • Li MO, Sanjabi S, FlavellRA. Transforming growth Factor-betacontrols development, homeostasis and tolerance of T-cells by regulatory Tvcell-dependene and -independent mechanisms. Immunity 2006; 25(3) :455-471. (Pubitemid 44354214)
    • (2006) Immunity , vol.25 , Issue.3 , pp. 455-471
    • Li, M.O.1    Sanjabi, S.2    Flavell, RichardA.3
  • 45
    • 33846340789 scopus 로고    scopus 로고
    • FOXP3: Not just for regulatory T-cells anymore
    • Ziegler SF. FOXP3: Not just for regulatory T-cells anymore. Eur J Immunol2007; 37(1) :21-23.
    • Eur J Immunol2007 , vol.37 , Issue.1 , pp. 21-23
    • Ziegler, S.F.1
  • 46
    • 50549098084 scopus 로고    scopus 로고
    • Identification of a regulatory T-cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression
    • Wang R, Wan Q, Kozhaya L, et al. Identification of a regulatory T-cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. PLoS ONE 2008; 3(7):e2705
    • (2008) PLoS ONE , vol.3 , Issue.7
    • Wang, R.1    Wan, Q.2    Kozhaya, L.3
  • 47
    • 52649179291 scopus 로고    scopus 로고
    • Notch l and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T-cells
    • Samon JB, Champhekar A, Minter LM, et al. Notch l and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T-cells. Blood 2008; 112(5):1813-1821.
    • (2008) Blood , vol.112 , Issue.5 , pp. 1813-1821
    • Samon, J.B.1    Champhekar, A.2    Minter, L.M.3
  • 48
    • 33845935950 scopus 로고    scopus 로고
    • IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T-cells
    • Burchill MA, YangJ, Vogrenhuber C, et al. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T-cells. J Immunol2007; 178(1):280-290.
    • J Immunol2007 , vol.178 , Issue.1 , pp. 280-290
    • Burchill, M.A.1    YangJ Vogrenhuber, C.2
  • 52
    • 20444373376 scopus 로고    scopus 로고
    • Rapamycin selectivelyexpands CD4+CD25+FoxP3+ regulatory T-cells
    • Battaglia M, Stabilini A, Roncarolo MG. Rapamycin selectivelyexpands CD4+CD25+FoxP3+ regulatory T-cells. Blood 2005: 105(12):4743-4748.
    • (2005) Blood , vol.105 , Issue.12 , pp. 4743-4748
    • Battaglia, M.1    Stabilini, A.2    Roncarolo, M.G.3
  • 54
    • 51349086288 scopus 로고    scopus 로고
    • Use of sirolimus in IPEX and IPEX-like children
    • Yong PL, Russo P, Sullivan KE. Use of sirolimus in IPEX and IPEX-like children. J Clin Irnrnunol 2008: 28(5):581-587.
    • (2008) J Clin Irnrnunol , vol.28 , Issue.5 , pp. 581-587
    • Yong, P.L.1    Russo, P.2    Sullivan, K.E.3
  • 55
    • 42949091388 scopus 로고    scopus 로고
    • Regulation of FoxP3 regulatory T-cells and Th17 cells by rerinoids
    • Kim CH. Regulation of FoxP3 regulatory T-cells and Th17 cells by rerinoids. Clin Dev Immunol2008; 2008:416910.
    • (2008) Clin Dev Immunol , vol.2008 , pp. 416910
    • Kim, C.H.1
  • 57
    • 0021164605 scopus 로고
    • Nutritional factors and autoimmunity. IV. Dietary vitamin A deprivation induces a selective increase in IgM autoantibodies and hypergammaglobulinemia in New Zealand black mice
    • Gershwin ME, Lentz DR, Beach RS et al. Nutritional factors and autoimmunity. IV. Dietary vitamin A deprivation induces a selective increase in IgM autoant ibodies and hypergammaglobulinemia in New Zealand Black mice. J 1mmunol 1984: 133(1):222-226. (Pubitemid 14077906)
    • (1984) Journal of Immunology , vol.133 , Issue.1 , pp. 222-226
    • Gershwin, M.E.1    Lentz, D.R.2    Beach, R.S.3    Hurley, L.S.4
  • 58
    • 55549084247 scopus 로고    scopus 로고
    • Retinoic acid enhances Foxp3 induction indirectly by relievinginhibition from CD4+CD44hi CelIs
    • Hill lA. Hall lA, Sun CM, et al. Retinoic acid enhances Foxp3 induction indirectly by relievinginhibition from CD4+CD44hi CelIs. Immunity 2008; 29(5) :758-770.
    • (2008) Immunity , vol.29 , Issue.5 , pp. 758-770
    • Hilll, A.1    Halll, A.2    Sun, C.M.3
  • 60
    • 49649107703 scopus 로고    scopus 로고
    • DNA methylation controls Foxp3 gene expression
    • Polan sky lK. Kretschmer K, Freyer L, et al. DNA methylation controls Foxp3 gene expression. Eur 1 Immunol2008; 38(6) :1654-1663.
    • (2008) Eur I Immunol , vol.38 , Issue.6 , pp. 1654-1663
    • Polansky, L.K.1    Kretschmer, K.2    Freyer, L.3
  • 61
    • 38349095578 scopus 로고    scopus 로고
    • Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
    • Tone Y, Furuuchi K, Kojima Y, et al. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer. Nat Immunol 2008; 9(2):194-202.
    • (2008) Nat Immunol , vol.9 , Issue.2 , pp. 194-202
    • Tone, Y.1    Furuuchi, K.2    Kojima, Y.3
  • 62
    • 47249085266 scopus 로고    scopus 로고
    • STAT6 Inhibits TGF-betal-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor
    • Takaki H. Ichiyama K, Koga K, et al. STAT6 Inhibits TGF-betal-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor. 1 Bioi Chern 2008; 283(22):14955-14962.
    • (2008) I Bioi Chern , vol.283 , Issue.22 , pp. 14955-14962
    • Takaki, H.1    Ichiyama, K.2    Koga, K.3
  • 63
    • 59849085588 scopus 로고    scopus 로고
    • Epigenetic regulation of Foxp3 expression in regulatory T-cells by DNA methylation
    • Lal G. Zhang N. van der Touw Wet al. Epigenetic regulation of Foxp3 expression in regulatory T-cells by DNA methylation. 1 Immunol2009; 182(1):259-273.
    • (2009) I Immunol , vol.182 , Issue.1 , pp. 259-273
    • Lal, G.1    Zhang, N.2    Van Der Touw, W.3
  • 66
    • 30444443314 scopus 로고    scopus 로고
    • Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
    • DOI 10.1182/blood-2005-07-2737
    • Zhou G. Drake CG. LevitskyHI. Amplification of rumor-specific regulatory T-cellsfolIowingtherapeutic cancer vaccines. Blood 2006; 107(2):628-636. (Pubitemid 43076387)
    • (2006) Blood , vol.107 , Issue.2 , pp. 628-636
    • Zhou, G.1    Drake, C.G.2    Levitsky, H.I.3
  • 67
    • 33846913897 scopus 로고    scopus 로고
    • Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance
    • Zhou G. Levitsky HI. Narural regulatory T-celIs and de novo-induced regulatory T-celIs contribute independently to rumor-specific tolerance. 1 Immunol2007; 178(4) :2155-2162 (Pubitemid 46233413)
    • (2007) Journal of Immunology , vol.178 , Issue.4 , pp. 2155-2162
    • Zhou, G.1    Levitsky, H.I.2
  • 68
    • 33746887327 scopus 로고    scopus 로고
    • Comparative analysis of regulatory and effector T cells in progressively growing versus rejecting tumors of similar origins
    • DOI 10.1158/0008-5472.CAN-06-0556
    • Buil O. Uppaluri R. Hsieh CS, et al. Comparative analysisof regulatory and effector T-cells in progressively growing versus rejecting rumors of similar origins. Cancer Res 2006; 66(14) :7301-7309. (Pubitemid 44197712)
    • (2006) Cancer Research , vol.66 , Issue.14 , pp. 7301-7309
    • Bui, J.D.1    Uppaluri, R.2    Hsieh, C.-S.3    Schreiber, R.D.4
  • 69
    • 35548950221 scopus 로고    scopus 로고
    • Regulatory T-cell inhibition versus depletion: The right choice in cancer immunotherapy
    • DOI 10.1038/nrc2250, PII NRC2250
    • Colombo MP, Piconese S. Regulatory-T-celI inhibition versus depletion : The right choice in cancer immunotherapy. Nat Rev Cancer 2007; 7(11):880-887. (Pubitemid 350006256)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.11 , pp. 880-887
    • Colombo, M.P.1    Piconese, S.2
  • 73
    • 34748837333 scopus 로고    scopus 로고
    • Biochemistry and therapeutic implications of mechanisms involved in FOXP3 activity in immune suppression
    • DOI 10.1016/j.coi.2007.07.006, PII S0952791507001197, Hematopoietic cell death/Immunogenetics/Transplantation
    • Li B. Saouaf SJ, Samanta A, et al. Biochemistry and therapeutic implications ofmechanisms involved in FOXP3 activity in immune suppression. CUrt Opin Immunol2007; 19(5):583-588. (Pubitemid 47487453)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.5 , pp. 583-588
    • Li, B.1    Saouaf, S.J.2    Samanta, A.3    Shen, Y.4    Hancock, W.W.5    Greene, M.I.6
  • 75
    • 2242423605 scopus 로고    scopus 로고
    • + regulatory T cells control Leishmania major persistence and immunity
    • DOI 10.1038/nature01152
    • Belkaid Y. Piccirillo CA. Mendez S, et al. CD4+CD25+ regulatory T-celIs control Leishmania major persistence and immunity. Nature 2002; 420(6915):502-507. (Pubitemid 35477041)
    • (2002) Nature , vol.420 , Issue.6915 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 77
    • 44849123303 scopus 로고    scopus 로고
    • Role of Foxp3 -positive regulatory T-cells during infection
    • Belkaid Y. Role of Foxp3 -positive regulatory T-cells during infection. Eur 1 Immunol 2008; 38(4) :918-921.
    • (2008) Eur 1 Immunol , vol.38 , Issue.4 , pp. 918-921
    • Belkaid, Y.1
  • 78
    • 0022815017 scopus 로고
    • Immunosuppression in viral infections
    • Rouse BT, Horohov OW. Immunosuppression in viral infections. Rev Infect Dis 1986; 8(6):850-873.
    • (1986) Rev Infect Dis , vol.8 , Issue.6 , pp. 850-873
    • Rouse, B.T.1    Horohov, O.W.2
  • 80
    • 0036203432 scopus 로고    scopus 로고
    • Viruses and autoimmunity: An affair but not a marriage contract
    • DOI 10.1002/rmv.347
    • Rouse BT, Deshpande S. Viruses and autoimmuniry: An affair but not a marriage contract. Rev Med Yiro12002; 12(2):107-113. (Pubitemid 34273045)
    • (2002) Reviews in Medical Virology , vol.12 , Issue.2 , pp. 107-113
    • Rouse, B.T.1    Deshpande, S.2
  • 84
    • 0034989804 scopus 로고    scopus 로고
    • T cell signaling mechanisms that regulate HIV-1 infection
    • DOI 10.1385/IR:23:2-3:167
    • Unutmaz D. T-cell signaling mechanisms that regulate HIY-l infection. Immunol Res 2001 ; 23(2-3) :167-177 (Pubitemid 32575358)
    • (2001) Immunologic Research , vol.23 , Issue.2-3 , pp. 167-177
    • Unutmaz, D.1
  • 86
    • 0027692154 scopus 로고
    • Multifactorial nature of human immunodeficiency virus disease: Implications for therapy
    • Fauci AS. Multifactorial nature of human immunodeficiency virus disease: Implications for therapy. Science 1993; 262(5136) :1011-1018. (Pubitemid 24035036)
    • (1993) Science , vol.262 , Issue.5136 , pp. 1011-1018
    • Fauci, A.S.1
  • 87
    • 45949112196 scopus 로고    scopus 로고
    • CD127 and CD25 expression defines CD4+ Tcell subsers that are differentially depleted during HIV infection
    • Dunham RM. Cervasi B. BrenchleyJM, et al. CD127 and CD25 expression defines CD4+ Tcell subsers that are differentially depleted during HIV infection.J Immunol 2008; 180(8):5582-5592.
    • (2008) J Immunol , vol.180 , Issue.8 , pp. 5582-5592
    • Dunham, R.M.1    Cervasi, B.2    Brenchley, J.M.3
  • 88
    • 53449092578 scopus 로고    scopus 로고
    • FoxP3+CD4+ regulatory T-cells play an important role in acute HIV-l infection in humanized Rag2-/-gammaC-/- mice in vivo
    • Jiang Q,Zhang L. Wang R, et al. FoxP3+CD4+ regulatory T-cells play an important role in acute HIV-l infection in humanized Rag2-/-gammaC-/- mice in vivo. Blood 2008; 112(7):2858-2868.
    • (2008) Blood , vol.112 , Issue.7 , pp. 2858-2868
    • Jiang, Q.1    Zhang, L.2    Wang, R.3
  • 89
    • 8644280556 scopus 로고    scopus 로고
    • + regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
    • DOI 10.1182/blood-2004-01-0365
    • Weiss L. Donkova-Petrini V. Caccavelli L, et al. Human immunodeficiency virus-driven expansion of CD4+CD25+ Regulatory T-cells which suppress HIV-specific CD4 T-cell responses in HIV-infected patients Blood 2004; Nov 15;104(10):3249-56 (Pubitemid 39507143)
    • (2004) Blood , vol.104 , Issue.10 , pp. 3249-3256
    • Weiss, L.1    Donkova-Petrini, V.2    Caccavelli, L.3    Balbo, M.4    Carbonneil, C.5    Levy, Y.6
  • 91
    • 10744227590 scopus 로고    scopus 로고
    • + Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens
    • DOI 10.1128/JVI.78.5.2454-2459.2004
    • Aandahl EM, Michaelsson J. Moretto WJ, et al. Human CD4+ CD25+ regulatory T-cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens J Virol 2004; 78(5):2454-2459. (Pubitemid 38228938)
    • (2004) Journal of Virology , vol.78 , Issue.5 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 92
    • 33746383248 scopus 로고    scopus 로고
    • Regulatory T-cells in virus infections
    • Rouse BT, Sarangi PP. Suvas S. Regulatory T-cells in virus infections. Immunol Rev 2006 ; 212:272-286.
    • (2006) Immunol Rev , vol.212 , pp. 272-286
    • Rouse, B.T.1    Sarangi, P.P.2    Suvas, S.3
  • 93
    • 34447542374 scopus 로고    scopus 로고
    • FoxP3 enhances HIV-1 gene expression by modulating NFκB occupancy at the long terminal repeat in human T cells
    • DOI 10.1074/jbc.M702051200
    • Holmes D. Knudsen G. Mackey-Cu shman S, et al. FoxP3 enhances HIV-l gene expression by modulating NFkappaB occupancy at the long terminal repeat in human T-cells.J Bioi Chern 2007; 282(22) :15973-15980. (Pubitemid 47100335)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 15973-15980
    • Holmes, D.1    Knudsen, G.2    Mackey-Cushman, S.3    Su, L.4
  • 94
    • 33646255425 scopus 로고    scopus 로고
    • Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways
    • Grant C. Oh U. Fugo K, et al. Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways. PLoS Pathog 2006; 2(4):e33.
    • (2006) PLoS Pathog , vol.2 , Issue.4
    • Grant, C.1    Oh, U.2    Fugo, K.3
  • 95
    • 54549119031 scopus 로고    scopus 로고
    • FOXP3 inhibits HIV-l infection of CD4 Tvcells via inhibition of LTR transcriptional activity
    • Selliah N, Zhang M, White S, et al. FOXP3 inhibits HIV-l infection of CD4 Tvcells via inhibition of LTR transcriptional activity. Virology 2008; 381(2) :161-167.
    • (2008) Virology , vol.381 , Issue.2 , pp. 161-167
    • Selliah, N.1    Zhang, M.2    White, S.3
  • 96
    • 50549103258 scopus 로고    scopus 로고
    • Immune modulation and chronic grafi-versus-hosr disease
    • Soiffer R. Immune modulation and chronic grafi-versus-hosr disease. Bone Marrow Transplant 2008; 42(Suppll):S66-S69.
    • (2008) Bone Marrow Transplant , vol.42 , Issue.SUPPL. 1
    • Soiffer, R.1
  • 97
    • 34248679904 scopus 로고    scopus 로고
    • + regulatory T cells in transplantation: Progress, challenges and prospects
    • DOI 10.1111/j.1600-6143.2007.01829.x
    • Kang SM. Tang Q,BluestoneJA. CD4+CD25+ regulatory T-cells in transplantation : Progress. challenges and prospects. AmJ Transplant 2007; 7(6):1457-1463. (Pubitemid 46776267)
    • (2007) American Journal of Transplantation , vol.7 , Issue.6 , pp. 1457-1463
    • Kang, S.M.1    Tang, Q.2    Bluestone, J.A.3
  • 98
    • 49249133433 scopus 로고    scopus 로고
    • Critical evaluation of regulatory T-cells in autoimmunit y: Are the most potent regularory specificities being ignored ?
    • Vandenbark AA. Offner H. Critical evaluation of regulatory T-cells in autoimmunit y: Are the most potent regularory specificities being ignored ? Immunology 2008; 125(1):1-13.
    • (2008) Immunology , vol.125 , Issue.1 , pp. 1-13
    • Vandenbark, A.A.1    Offner, H.2
  • 99
    • 0032538918 scopus 로고    scopus 로고
    • + T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis
    • DOI 10.1084/jem.188.10.1883
    • Olivares-VillagomezD, Wang Y. Lafaillen. Regulatory CD4(+) T-cells expressing endogenous T-cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneou s autoimmune encephalomyelitis.J Exp Med 1998; 188(10):1883-1894. (Pubitemid 28536776)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.10 , pp. 1883-1894
    • Olivares-Villagomez, D.1    Wang, Y.2    Lafaille, J.J.3
  • 100
    • 79959590522 scopus 로고    scopus 로고
    • FOXP3/Scurfin gene polymorphism is associated with adult onset type 1 diabetes in Japanese. especially in women and slowly progressive-type patients
    • Iwase K. Shimada A, Kawai T, et al. FOXP3/Scurfin gene polymorphism is associated with adult onset type 1 diabetes in Japanese. especially in women and slowly progressive-type patients. Autoimmunity 2008:1.
    • (2008) Autoimmunity , vol.1
    • Iwase, K.1    Shimada, A.2    Kawai, T.3
  • 101
    • 57749174515 scopus 로고    scopus 로고
    • Diverse foxp3 expression in children with type 1 diabetes and celiac disease
    • KivlingA, Nilsson L. Falth-MagnussonK, et al. Diverse foxp3 expression in children with type 1 diabetes and celiac disease. Ann NY Acad Sci 2008: 1150:273-277.
    • (2008) Ann NY Acad Sci , vol.1150 , pp. 273-277
    • KivlingA Nilsson, L.1    Falth-Magnusson, K.2
  • 102
    • 18244400088 scopus 로고    scopus 로고
    • + regulatory T cells during autoimmune diabetes
    • DOI 10.1084/jem.20042398
    • Pop SM. Wong CPo Culton DA, et al. Single cell analysis shows decreasing FoxP3 and TGFbetal coexpressing CD4+CD25+ regulato ry T-cells during autoimmune diabetes. J Exp Med 2005 : 201(8) :1333-1346. (Pubitemid 40629075)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.8 , pp. 1333-1346
    • Pop, S.M.1    Wong, C.P.2    Culton, D.A.3    Clarke, S.H.4    Tisch, R.5
  • 103
    • 58149188480 scopus 로고    scopus 로고
    • The effector Tvcells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T-cells
    • Schneider A. Rieck M, Sanda S, et al. The effector Tvcells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T-cells.J Immunol 2008: 181(10):7350-7355.
    • (2008) J Immunol , vol.181 , Issue.10 , pp. 7350-7355
    • Schneider, A.1    Rieck, M.2    Sanda, S.3
  • 104
    • 48649106615 scopus 로고    scopus 로고
    • Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T-cells promotes diabetes J
    • Waid DM. Vaitaitis GM, Pennock ND, et al. Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T-cells promotes diabetes J Leukoc Bioi 2008: 84(2) :431-439.
    • (2008) Leukoc Bioi , vol.84 , Issue.2 , pp. 431-439
    • Waid, D.M.1    Vaitaitis, G.M.2    Pennock, N.D.3
  • 106
    • 34047210905 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1111/j.1365-2567.2007.02546.x
    • Mellanby RJ. Thomas D, PhillipsJM, et al. Diabetes in non-obese diabetic mice is not associated with quantitative changes in CD4+ CD25+ Foxp3+ regulatory T-cells. Immunology 2007; 121(1):15-28. (Pubitemid 46537670)
    • (2007) Immunology , vol.121 , Issue.1 , pp. 15-28
    • Mellanby, R.J.1    Thomas, D.2    Phillips, J.M.3    Cooke, A.4
  • 107
    • 40549120324 scopus 로고    scopus 로고
    • Role of regulatory T cells for the treatment of type 1 diabetes mellitus
    • DOI 10.1055/s-2008-1042427, Cellular Therapies
    • Jaeckel E. Mpofu N. SaalNet al. Role of regulatory T-cells for the treatment of type I diabetes mellitus. Horm Metab Res 2008; 40(2) :126-136. (Pubitemid 351363424)
    • (2008) Hormone and Metabolic Research , vol.40 , Issue.2 , pp. 126-136
    • Jaeckel, E.1    Mpofu, N.2    Saal, N.3    Manns, M.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.