Twenty-first century Foxp3

Nature Immunology

Volumn 4, Issue 4, 2003, Pages 304-306

  O'Garra, Anne ^a   Vieira, Paulo ^b  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY; CACHEXIA; CELL ACTIVITY; CELL MATURATION; CELL PROLIFERATION; GENE INDUCTION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; LYMPHOCYTE FUNCTION; LYMPHOCYTIC INFILTRATION; LYMPHOPROLIFERATIVE DISEASE; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; LYMPHOPROLIFERATIVE DISORDERS; MICE; T-LYMPHOCYTES; TRANSCRIPTION FACTORS;

EID: 0037383757     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni0403-304     Document Type: Article

References (16)

1. + regulatory T cells. Nat. Immunol. 4, 330-336 (2003).
2. + T regulatory cells. Nat. Immunol. 4, 337-342 (2003).
3. + regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 182, 18-32 (2001).
4. + suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2, 389-400 (2002).
5. Maloy, K.J. & Powrie, F. Regulatory T cells in the control of immune pathology. Nat. Immunol. 2, 816-822 (2001).
6. Apostolou, I., Sarukhan, A., Klein, L. & von Boehmer, H. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3, 756-763 (2002).
7. Furtado, G.C. et al. Regulatory T cells in spontaneous autoimmune encephalomyelitis. Immunol. Rev. 182, 122-134 (2001).
8. + regulatory T cells control Leishmania major persistence and immunity. Nature 420, 502-507 (2002).
9. Annacker, O., Pimenta-Araujo, R., Burlen-Defranoux, O. & Bandeira, A. On the ontogeny and physiology of regulatory T cells. Immunol. Rev. 182, 5-17 (2001).
10. Hori, S., Nomura,T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor FoxP3. Science 299, 1057-1061 (2003).
11. Brunkow, M.E. et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27, 68-73 (2001).
12. Chatila, T.A. et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106, R75-R81 (2000).
13. Schubert, L.A., Jeffery, E., Zhang, Y., Ramsdell, F. & Ziegler, S.F. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J. Biol. Chem. 276, 37672-37679 (2001).
14. Barthlott, T., Kassiotis, G. & Stockinger, B. T cell regulation as a side effect of homeostasis and competition. J. Exp. Med. 197, 451-460 (2003).
15. + T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197, 111-119 (2003).
16. + T cell-mediated suppression by dendritic cells. Science 299, 1033-1036 (2003).