메뉴 건너뛰기




Volumn 14, Issue 1, 2004, Pages 11-20

Neuropathology and Pathogenesis of Encephalitis Following Amyloid-β Immunization in Alzheimer's Disease

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE VACCINE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CD16 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD5 ANTIGEN; CD57 ANTIGEN; CD7 ANTIGEN; CD8 ANTIGEN; GRANZYME A; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; METHYLPREDNISOLONE; MITOGEN ACTIVATED PROTEIN KINASE P38; PREDNISONE; QS 21; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TAU PROTEIN;

EID: 1042265187     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2004.tb00493.x     Document Type: Article
Times cited : (550)

References (50)
  • 1
    • 0035208849 scopus 로고    scopus 로고
    • Activation of JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis
    • Atzori C, Guetti B, Piva R, Srinivasan AN, Zolo P, Delisle MB, Mirra SS, Migheli A (2001) Activation of JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. J Neuropothol Exp Neurol 60:1190-11197.
    • (2001) J Neuropothol Exp Neurol , vol.60 , pp. 1190-11197
    • Atzori, C.1    Guetti, B.2    Piva, R.3    Srinivasan, A.N.4    Zolo, P.5    Delisle, M.B.6    Mirra, S.S.7    Migheli, A.8
  • 2
    • 0033835996 scopus 로고    scopus 로고
    • Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
    • Bard F, Cannon C, Barbour R, Burke RL, Games D, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K et al (2000) Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nature Med 6:916-919.
    • (2000) Nature Med , vol.6 , pp. 916-919
    • Bard, F.1    Cannon, C.2    Barbour, R.3    Burke, R.L.4    Games, D.5    Grajeda, H.6    Guido, T.7    Hu, K.8    Huang, J.9    Johnson-Wood, K.10    Khan, K.11
  • 3
    • 0032890439 scopus 로고    scopus 로고
    • AD and oxidative stress: Implications for novel therapeutic approaches
    • Behl C (1999) AD and oxidative stress: implications for novel therapeutic approaches. Progr Neurobiol 57:301-323.
    • (1999) Progr Neurobiol , vol.57 , pp. 301-323
    • Behl, C.1
  • 4
    • 0036769733 scopus 로고    scopus 로고
    • GSK-3beta signaling: Casting a wide net in Alzheimer's disease
    • Bhat RV, Budd SL (2002) GSK-3beta signaling: casting a wide net in Alzheimer's disease. Neurosignals 11:251-261.
    • (2002) Neurosignals , vol.11 , pp. 251-261
    • Bhat, R.V.1    Budd, S.L.2
  • 5
    • 0036127580 scopus 로고    scopus 로고
    • Setback to Alzheimer vaccine studies
    • Birmingham K, Frantz S (2002) Setback to Alzheimer vaccine studies. Nat Med 8:199-200.
    • (2002) Nat Med , vol.8 , pp. 199-200
    • Birmingham, K.1    Frantz, S.2
  • 7
    • 0000135440 scopus 로고    scopus 로고
    • Temporal sequence of Alzheimer's disease-related pathology
    • Peters A, Morrison JH (eds.), Chapter 14, Kluver Academic/Plenum Publishers: New York, Boston, Dordrecht, London, Moscow
    • Braak H, Braak E (1999) Temporal sequence of Alzheimer's disease-related pathology. In: Cerebral Cortex, vol 74: Neurodegenerative and age-related changes in structure and function of cerebral cortex, Peters A, Morrison JH (eds.), Chapter 14, pp. 475-512, Kluver Academic/Plenum Publishers: New York, Boston, Dordrecht, London, Moscow.
    • (1999) Cerebral Cortex, Vol 74: Neurodegenerative and Age-Related Changes in Structure and Function of Cerebral Cortex , vol.74 , pp. 475-512
    • Braak, H.1    Braak, E.2
  • 8
    • 0025002019 scopus 로고
    • Alzheimer patients and Down patients: Abnormal presynaptic terminals are related to cerebral pre-amyloid deposits
    • Bugiani O, Giaccone G, Verga L, Pollo B, Ghetti B, Frangione B, Tagliavini F (1990) Alzheimer patients and Down patients: Abnormal presynaptic terminals are related to cerebral pre-amyloid deposits. Neurosci Lett 119:56-59.
    • (1990) Neurosci Lett , vol.119 , pp. 56-59
    • Bugiani, O.1    Giaccone, G.2    Verga, L.3    Pollo, B.4    Ghetti, B.5    Frangione, B.6    Tagliavini, F.7
  • 9
    • 0037203825 scopus 로고    scopus 로고
    • Nerve inflammation halts trial for Alzheimer's drug
    • Check E (2002) Nerve inflammation halts trial for Alzheimer's drug. Nature 415:462.
    • (2002) Nature , vol.415 , pp. 462
    • Check, E.1
  • 10
    • 0032535483 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathways: On protein death and cell life
    • Ciechanover A (1998) The ubiquitin-proteasome pathways: on protein death and cell life. EMBO J 17:7151-7160.
    • (1998) EMBO J , vol.17 , pp. 7151-7160
    • Ciechanover, A.1
  • 11
    • 0035488986 scopus 로고    scopus 로고
    • The renaissance of GSK3
    • Cohen P, Frame S (2001) The renaissance of GSK3. Nat Rev 2:769-776.
    • (2001) Nat Rev , vol.2 , pp. 769-776
    • Cohen, P.1    Frame, S.2
  • 13
    • 0036942843 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK-3) is associated with neuronal and glial hyper-phosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration
    • Ferrer I, Barrachina M, Puig B (2002) Glycogen synthase kinase-3 (GSK-3) is associated with neuronal and glial hyper-phosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Acta Neuropathol 104:583-591.
    • (2002) Acta Neuropathol , vol.104 , pp. 583-591
    • Ferrer, I.1    Barrachina, M.2    Puig, B.3
  • 14
    • 0035659377 scopus 로고    scopus 로고
    • Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/ JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies
    • Ferrer I, Blanco R, Carmona M, Puig B (2001) Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/ JNK-P), and calcium/ calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies. J Neural Transm 108:1397-1415.
    • (2001) J Neural Transm , vol.108 , pp. 1397-1415
    • Ferrer, I.1    Blanco, R.2    Carmona, M.3    Puig, B.4
  • 16
    • 0031916545 scopus 로고    scopus 로고
    • Dystrophic neurites of senile plaques are defective in proteins involved in exocytosis and neurotransmission
    • Ferrer I, Martí E, Tortosa A, Blasi J (1998) Dystrophic neurites of senile plaques are defective in proteins involved in exocytosis and neurotransmission. J Neuropathol Exp Neurol 57:218-225.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 218-225
    • Ferrer, I.1    Martí, E.2    Tortosa, A.3    Blasi, J.4
  • 17
    • 0028830958 scopus 로고
    • Localization of superoxide dismutases in Alzheimer's disease and Down's syndrome neocortex and hippocampus
    • Furuta A, Price DL, Parp CA, Troncoso JC, Xu ZS, Tangiuchi N, Martin LJ (1995) Localization of superoxide dismutases in Alzheimer's disease and Down's syndrome neocortex and hippocampus. Am J Pathol 146:357-362.
    • (1995) Am J Pathol , vol.146 , pp. 357-362
    • Furuta, A.1    Price, D.L.2    Parp, C.A.3    Troncoso, J.C.4    Xu, Z.S.5    Tangiuchi, N.6    Martin, L.J.7
  • 21
    • 0037208951 scopus 로고    scopus 로고
    • Incidence of cerebrovascular lesions in Alzheimer's disease: A post-mortem study
    • Jellinger KA, Attems J (2003) Incidence of cerebrovascular lesions in Alzheimer's disease: a post-mortem study. Acta Neuropathol 105:14-17.
    • (2003) Acta Neuropathol , vol.105 , pp. 14-17
    • Jellinger, K.A.1    Attems, J.2
  • 22
    • 0037381710 scopus 로고    scopus 로고
    • Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease
    • Keck S, Nitsch R, Grune T, Ulrich O (2003) Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease. J Neurochem 85:15-22.
    • (2003) J Neurochem , vol.85 , pp. 15-22
    • Keck, S.1    Nitsch, R.2    Grune, T.3    Ulrich, O.4
  • 26
    • 0035075334 scopus 로고    scopus 로고
    • Molecular dissection of the 11S REG (PA28) proteasome activators
    • Li J, Reichsteiner M (2001) Molecular dissection of the 11S REG (PA28) proteasome activators. Biochimie 83:373-383.
    • (2001) Biochimie , vol.83 , pp. 373-383
    • Li, J.1    Reichsteiner, M.2
  • 27
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • Markesbery WR, Carney JM (1999) Oxidative alterations in Alzheimer's disease. Brain Pathol 9:133-146.
    • (1999) Brain Pathol , vol.9 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 28
    • 0031596265 scopus 로고    scopus 로고
    • Mechanisms of synaptic pathology in Alzheimer's disease
    • Masliah E (1998) Mechanisms of synaptic pathology in Alzheimer's disease. J Neural Transm 53:147-158.
    • (1998) J Neural Transm , vol.53 , pp. 147-158
    • Masliah, E.1
  • 29
    • 0035057591 scopus 로고    scopus 로고
    • Neurofibrillary pathology in transgenic mice overexpressing V717F β-amyloid precursor protein
    • Masliah E, Sisk A, Mallory M, Games D (2001) Neurofibrillary pathology in transgenic mice overexpressing V717F β-amyloid precursor protein. J Neuropathol Exp Neurol 60:357-368.
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 357-368
    • Masliah, E.1    Sisk, A.2    Mallory, M.3    Games, D.4
  • 31
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: A case report
    • Nicoll JAR, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO (2003) Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report. Nat Med 9:448-452.
    • (2003) Nat Med , vol.9 , pp. 448-452
    • Nicoll, J.A.R.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 32
    • 0026823074 scopus 로고
    • Immunohistochemical evidence of oxidative stress in Alzheimer's disease
    • Pappolla MA, Omar RA, Kim KS, Robakis NK (1992) Immunohistochemical evidence of oxidative stress in Alzheimer's disease. Am J Pathol 140:621-628.
    • (1992) Am J Pathol , vol.140 , pp. 621-628
    • Pappolla, M.A.1    Omar, R.A.2    Kim, K.S.3    Robakis, N.K.4
  • 34
    • 0032229327 scopus 로고    scopus 로고
    • Reactive oxygen species mediate cellular damage in Alzheimer's disease
    • Perry G, Castellani RJ, Hirai K, Smith MA (1998) Reactive oxygen species mediate cellular damage in Alzheimer's disease. J Alzheimer Dis 1:45-55.
    • (1998) J Alzheimer Dis , vol.1 , pp. 45-55
    • Perry, G.1    Castellani, R.J.2    Hirai, K.3    Smith, M.A.4
  • 36
    • 0036359774 scopus 로고    scopus 로고
    • Protein degradation in human disease
    • Reboud-Ravaux M (edit.), Chapter 5, Springer-Verlag: Berlin, Heidelberg
    • Plemper RK, Hammond AL (2002) Protein degradation in human disease. In: Progress in molecular and sub-cellular biology, vol 29, Reboud-Ravaux M (edit.), Chapter 5, pp. 61-84, Springer-Verlag: Berlin, Heidelberg.
    • (2002) Progress in Molecular and Sub-Cellular Biology , vol.29 , pp. 61-84
    • Plemper, R.K.1    Hammond, A.L.2
  • 37
    • 0032971227 scopus 로고    scopus 로고
    • Degradation of cell proteins and the generation of MHC class I-presented peptides
    • Rock KL, Goldberg AL (1999) Degradation of cell proteins and the generation of MHC class I-presented peptides. Annu Rev Immunol 17:739-771.
    • (1999) Annu Rev Immunol , vol.17 , pp. 739-771
    • Rock, K.L.1    Goldberg, A.L.2
  • 38
    • 0036813085 scopus 로고    scopus 로고
    • Of mice and men: The relevance of transgenic mice Aβ immunizations to Alzheimer's disease
    • Roher AE, Kokjohn TA (2002) Of mice and men: the relevance of transgenic mice Aβ immunizations to Alzheimer's disease. J Alzheimer Dis 4:431-434.
    • (2002) J Alzheimer Dis , vol.4 , pp. 431-434
    • Roher, A.E.1    Kokjohn, T.A.2
  • 39
    • 0036580703 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinase and p38 in an Alzheimer disease model is associated with amyloid deposition
    • Savage MJ, Lin YG, Ciallella JR, Flood DG, Scott RW (2002) Activation of c-Jun N-terminal kinase and p38 in an Alzheimer disease model is associated with amyloid deposition. J Neurosci 22:3376-3385.
    • (2002) J Neurosci , vol.22 , pp. 3376-3385
    • Savage, M.J.1    Lin, Y.G.2    Ciallella, J.R.3    Flood, D.G.4    Scott, R.W.5
  • 41
    • 0034353223 scopus 로고    scopus 로고
    • The proteasome regulator PA28α/β can enhance antigen presentation without affecting 20S proteasome subunit composition
    • Schwartz K, Eggers M, Soza A, Koszinowski UH, Kloetzel PM, Groettrup M (2000) The proteasome regulator PA28α/β can enhance antigen presentation without affecting 20S proteasome subunit composition. Eur J Immunol 30:3672-3679.
    • (2000) Eur J Immunol , vol.30 , pp. 3672-3679
    • Schwartz, K.1    Eggers, M.2    Soza, A.3    Koszinowski, U.H.4    Kloetzel, P.M.5    Groettrup, M.6
  • 42
    • 0034884382 scopus 로고    scopus 로고
    • Immunization with a non-toxic/nonfibrillar amyloid- homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
    • Sigurdsson EM, Scholtzova H, Mehta PD, Frangione B, Wisniewski T (2001) Immunization with a non-toxic/nonfibrillar amyloid- homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am J Pathol 159:439-447.
    • (2001) Am J Pathol , vol.159 , pp. 439-447
    • Sigurdsson, E.M.1    Scholtzova, H.2    Mehta, P.D.3    Frangione, B.4    Wisniewski, T.5
  • 48
    • 0036770144 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase pathways in Alzheimer's disease
    • Zhu X, Lee HG, Raina AK, Perry G, Smith MA (2002) The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals 1:270-281.
    • (2002) Neurosignals , vol.1 , pp. 270-281
    • Zhu, X.1    Lee, H.G.2    Raina, A.K.3    Perry, G.4    Smith, M.A.5
  • 49
    • 0035142804 scopus 로고    scopus 로고
    • Activation and redistribution of c-Jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
    • Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA (2001) Activation and redistribution of c-Jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J Neurochem 76:435-441.
    • (2001) J Neurochem , vol.76 , pp. 435-441
    • Zhu, X.1    Raina, A.K.2    Rottkamp, C.A.3    Aliev, G.4    Perry, G.5    Boux, H.6    Smith, M.A.7
  • 50
    • 0033782845 scopus 로고    scopus 로고
    • Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease
    • Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA (2000) Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol 59:880-888.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 880-888
    • Zhu, X.1    Rottkamp, C.A.2    Boux, H.3    Takeda, A.4    Perry, G.5    Smith, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.