Microglia enhance β-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species

Journal of Neurochemistry

Volumn 83, Issue 4, 2002, Pages 973-983

  Qin, Liya ^a   Liu, Yuxin ^a   Cooper, Cynthia ^b   Liu, Bin ^a   Wilson, Belinda ^a   Hong, Jau Shyong ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b TRUMAN STATE UNIVERSITY   (United States)

Author keywords

amyloid; Cortical neurons; Mesencephalic neurons; Microglia; Nicotinamide adenine dinucleotide phosphate oxidase

Indexed keywords

AMYLOID BETA PROTEIN; CATALASE; DIPHENYLIODONIUM SALT; INTERLEUKIN 1BETA; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; MESENCEPHALON; MICROGLIA; MOUSE; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SCAVENGING SYSTEM;

AMYLOID BETA-PROTEIN; ANIMALS; CATALASE; CELLS, CULTURED; CEREBRAL CORTEX; COCULTURE TECHNIQUES; ENZYME INHIBITORS; INTERLEUKIN-1; MESENCEPHALON; MICE; MICE, INBRED C57BL; MICROGLIA; NADPH OXIDASE; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; RATS; RATS, INBRED F344; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0036845314     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01210.x     Document Type: Article

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