Protein-protein interaction inhibition (2P2I): Fewer and fewer undruggable targets

Combinatorial Chemistry and High Throughput Screening

Volumn 12, Issue 10, 2009, Pages 968-983

  Betzi, Stéphane ^a   Guerlesquin, Françoise ^a   Morelli, Xavier ^a  

^a CNRS   (France)

Author keywords

Docking; Drug design; Inhibitor; Mapping; NMR; Protein interaction; Virtual screening

Indexed keywords

PROTEIN INHIBITOR; PROTEIN PROTEIN INTERACTION INHIBITOR; UNCLASSIFIED DRUG;

BINDING SITE; CONSENSUS DEVELOPMENT; DRUG DETERMINATION; DRUG PROTEIN BINDING; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; MOLECULAR DOCKING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RADIATION SCATTERING; REVIEW; SCORING SYSTEM; STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ANIMALS; COMPUTATIONAL BIOLOGY; COMPUTING METHODOLOGIES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEINS;

EID: 71249096486     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/138620709789824736     Document Type: Review

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