-
1
-
-
0036548070
-
gamma-Secretase, Notch, Abeta and Alzheimer's disease: Where do the presenilins fit in?
-
10.1038/nrn785. 11967558
-
gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in? SS Sisodia PH St George-Hyslop, Nat Rev Neurosci 2002 3 4 281 290 10.1038/nrn785 11967558
-
(2002)
Nat Rev Neurosci
, vol.3
, Issue.4
, pp. 281-290
-
-
Sisodia, S.S.1
St George-Hyslop, P.H.2
-
2
-
-
0041355557
-
Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration
-
10.1146/annurev.neuro.26.041002.131334. 12730322
-
Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. D Selkoe R Kopan, Annu Rev Neurosci 2003 26 565 597 10.1146/annurev.neuro.26.041002.131334 12730322
-
(2003)
Annu Rev Neurosci
, vol.26
, pp. 565-597
-
-
Selkoe, D.1
Kopan, R.2
-
3
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
10.1126/science.286.5440.735. 10531052
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. R Vassar BD Bennett S Babu-Khan S Kahn EA Mendiaz P Denis DB Teplow S Ross P Amarante R Loeloff et al., Science 1999 286 5440 735 741 10.1126/science.286.5440.735 10531052
-
(1999)
Science
, vol.286
, Issue.5440
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
-
4
-
-
0033617402
-
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation
-
10.1016/S0092-8674(00)80748-5. 10319819
-
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. FG Gervais D Xu GS Robertson JP Vaillancourt Y Zhu J Huang A LeBlanc D Smith M Rigby MS Shearman et al., Cell 1999 97 3 395 406 10.1016/S0092-8674(00)80748-5 10319819
-
(1999)
Cell
, vol.97
, Issue.3
, pp. 395-406
-
-
Gervais, F.G.1
Xu, D.2
Robertson, G.S.3
Vaillancourt, J.P.4
Zhu, Y.5
Huang, J.6
LeBlanc, A.7
Smith, D.8
Rigby, M.9
Shearman, M.S.10
-
5
-
-
0033605252
-
Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases
-
10.1074/jbc.274.9.5823. 10026204
-
Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases. A Weidemann K Paliga U Durrwang FB Reinhard O Schuckert G Evin CL Masters, J Biol Chem 1999 274 9 5823 5829 10.1074/jbc.274.9.5823 10026204
-
(1999)
J Biol Chem
, vol.274
, Issue.9
, pp. 5823-5829
-
-
Weidemann, A.1
Paliga, K.2
Durrwang, U.3
Reinhard, F.B.4
Schuckert, O.5
Evin, G.6
Masters, C.L.7
-
6
-
-
0033597884
-
Alternative, nonsecretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8
-
10.1074/jbc.274.30.21011. 10409650
-
Alternative, nonsecretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8. L Pellegrini BJ Passer M Tabaton JK Ganjei L D'Adamio, J Biol Chem 1999 274 30 21011 21016 10.1074/jbc.274.30.21011 10409650
-
(1999)
J Biol Chem
, vol.274
, Issue.30
, pp. 21011-21016
-
-
Pellegrini, L.1
Passer, B.J.2
Tabaton, M.3
Ganjei, J.K.4
D'Adamio, L.5
-
7
-
-
0034488295
-
Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor
-
12214090
-
Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor. B Passer L Pellegrini C Russo RM Siegel MJ Lenardo G Schettini M Bachmann M Tabaton L D'Adamio, J Alzheimers Dis 2000 2 3-4 289 301 12214090
-
(2000)
J Alzheimers Dis
, vol.2
, Issue.3-4
, pp. 289-301
-
-
Passer, B.1
Pellegrini, L.2
Russo, C.3
Siegel, R.M.4
Lenardo, M.J.5
Schettini, G.6
Bachmann, M.7
Tabaton, M.8
D'Adamio, L.9
-
8
-
-
33845324145
-
C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression
-
12923068
-
C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression. HS Kim EM Kim JP Lee CH Park S Kim JH Seo KA Chang E Yu SJ Jeong YH Chong et al., FASEB J 2003 17 13 1951 1953 12923068
-
(2003)
FASEB J
, vol.17
, Issue.13
, pp. 1951-1953
-
-
Kim, H.S.1
Kim, E.M.2
Lee, J.P.3
Park, C.H.4
Kim, S.5
Seo, J.H.6
Chang, K.A.7
Yu, E.8
Jeong, S.J.9
Chong, Y.H.10
-
9
-
-
27744547991
-
SET protein (TAF1beta, I2PP2A) is involved in neuronal apoptosis induced by an amyloid precursor protein cytoplasmic subdomain
-
16162853
-
SET protein (TAF1beta, I2PP2A) is involved in neuronal apoptosis induced by an amyloid precursor protein cytoplasmic subdomain. A Madeira JM Pommet A Prochiantz B Allinquant, FASEB J 2005 19 13 1905 1907 16162853
-
(2005)
FASEB J
, vol.19
, Issue.13
, pp. 1905-1907
-
-
Madeira, A.1
Pommet, J.M.2
Prochiantz, A.3
Allinquant, B.4
-
10
-
-
33645105621
-
Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms
-
10.1111/j.1471-4159.2005.03578.x. 16405513
-
Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms. M Bentahir O Nyabi J Verhamme A Tolia K Horre J Wiltfang H Esselmann B De Strooper, J Neurochem 2006 96 3 732 742 10.1111/j.1471-4159. 2005.03578.x 16405513
-
(2006)
J Neurochem
, vol.96
, Issue.3
, pp. 732-742
-
-
Bentahir, M.1
Nyabi, O.2
Verhamme, J.3
Tolia, A.4
Horre, K.5
Wiltfang, J.6
Esselmann, H.7
De Strooper, B.8
-
11
-
-
52049112089
-
Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role
-
18764939. 10.1186/1750-1326-3-12
-
Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role. L Giliberto D Zhou R Weldon E Tamagno P De Luca M Tabaton L D'Adamio, Mol Neurodegener 2008 3 12 18764939 10.1186/1750-1326-3-12
-
(2008)
Mol Neurodegener
, vol.3
, pp. 12
-
-
Giliberto, L.1
Zhou, D.2
Weldon, R.3
Tamagno, E.4
De Luca, P.5
Tabaton, M.6
D'Adamio, L.7
-
12
-
-
34548699654
-
The gamma/epsilon-Secretase- Derived APP Intracellular Domain Fragments Regulate p53
-
10.2174/156720507781788945. 17908046
-
The gamma/epsilon-Secretase- Derived APP Intracellular Domain Fragments Regulate p53. F Checler C Sunyach R Pardossi-Piquard J Sevalle B Vincent T Kawarai N Girardot P St George-Hyslop CA da Costa, Curr Alzheimer Res 2007 4 4 423 426 10.2174/156720507781788945 17908046
-
(2007)
Curr Alzheimer Res
, vol.4
, Issue.4
, pp. 423-426
-
-
Checler, F.1
Sunyach, C.2
Pardossi-Piquard, R.3
Sevalle, J.4
Vincent, B.5
Kawarai, T.6
Girardot, N.7
St George-Hyslop, P.8
Da Costa, C.A.9
-
13
-
-
0035816661
-
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
-
10.1126/science.1058783. 11441186
-
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. X Cao TC Sudhof, Science 2001 293 5527 115 120 10.1126/science.1058783 11441186
-
(2001)
Science
, vol.293
, Issue.5527
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
14
-
-
0037067655
-
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein
-
10.1016/S0092-8674(02)00809-7. 12150997
-
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. SH Baek KA Ohgi DW Rose EH Koo CK Glass MG Rosenfeld, Cell 2002 110 1 55 67 10.1016/S0092-8674(02) 00809-7 12150997
-
(2002)
Cell
, vol.110
, Issue.1
, pp. 55-67
-
-
Baek, S.H.1
Ohgi, K.A.2
Rose, D.W.3
Koo, E.H.4
Glass, C.K.5
Rosenfeld, M.G.6
-
15
-
-
34748897213
-
Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1
-
17920016. 10.1016/j.neuron.2007.08.008
-
Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Q Liu CV Zerbinatti J Zhang HS Hoe B Wang SL Cole J Herz L Muglia G Bu, Neuron 2007 56 1 66 78 17920016 10.1016/j.neuron.2007.08.008
-
(2007)
Neuron
, vol.56
, Issue.1
, pp. 66-78
-
-
Liu, Q.1
Zerbinatti, C.V.2
Zhang, J.3
Hoe, H.S.4
Wang, B.5
Cole, S.L.6
Herz, J.7
Muglia, L.8
Bu, G.9
-
16
-
-
20444398562
-
Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP
-
10.1016/j.neuron.2005.04.008. 15944124
-
Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. R Pardossi-Piquard A Petit T Kawarai C Sunyach C Alves da Costa B Vincent S Ring L D'Adamio J Shen U Muller et al., Neuron 2005 46 4 541 554 10.1016/j.neuron. 2005.04.008 15944124
-
(2005)
Neuron
, vol.46
, Issue.4
, pp. 541-554
-
-
Pardossi-Piquard, R.1
Petit, A.2
Kawarai, T.3
Sunyach, C.4
Alves Da Costa, C.5
Vincent, B.6
Ring, S.7
D'Adamio, L.8
Shen, J.9
Muller, U.10
-
17
-
-
5444275067
-
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
-
10.1242/jcs.01323. 15331662
-
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. RC von Rotz BM Kohli J Bosset M Meier T Suzuki RM Nitsch U Konietzko, J Cell Sci 2004 117 Pt 19 4435 4448 10.1242/jcs.01323 15331662
-
(2004)
J Cell Sci
, vol.117
, Issue.PART 19
, pp. 4435-4448
-
-
Von Rotz, R.C.1
Kohli, B.M.2
Bosset, J.3
Meier, M.4
Suzuki, T.5
Nitsch, R.M.6
Konietzko, U.7
-
18
-
-
34547539177
-
Presenilin/gammasecretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression
-
17556541. 10.1073/pnas.0703903104
-
Presenilin/gammasecretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression. YW Zhang R Wang Q Liu H Zhang FF Liao H Xu, Proc Natl Acad Sci USA 2007 104 25 10613 10618 17556541 10.1073/pnas.0703903104
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.25
, pp. 10613-10618
-
-
Zhang, Y.W.1
Wang, R.2
Liu, Q.3
Zhang, H.4
Liao, F.F.5
Xu, H.6
-
19
-
-
0037452773
-
JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65
-
12563035. 10.1073/pnas.0437908100
-
JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65. MH Scheinfeld S Matsuda L D'Adamio, Proc Natl Acad Sci USA 2003 100 4 1729 1734 12563035 10.1073/pnas.0437908100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.4
, pp. 1729-1734
-
-
Scheinfeld, M.H.1
Matsuda, S.2
D'Adamio, L.3
-
20
-
-
0037076398
-
The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling
-
12011466. 10.1073/pnas.102192599
-
The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. R Roncarati N Sestan MH Scheinfeld BE Berechid PA Lopez O Meucci JC McGlade P Rakic L D'Adamio, Proc Natl Acad Sci USA 2002 99 10 7102 7107 12011466 10.1073/pnas.102192599
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.10
, pp. 7102-7107
-
-
Roncarati, R.1
Sestan, N.2
Scheinfeld, M.H.3
Berechid, B.E.4
Lopez, P.A.5
Meucci, O.6
McGlade, J.C.7
Rakic, P.8
D'Adamio, L.9
-
21
-
-
0037007140
-
A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP
-
11917117. 10.1073/pnas.072033799
-
A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP. MA Leissring MP Murphy TR Mead Y Akbari MC Sugarman M Jannatipour B Anliker U Muller P Saftig B De Strooper et al., Proc Natl Acad Sci USA 2002 99 7 4697 4702 11917117 10.1073/pnas.072033799
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.7
, pp. 4697-4702
-
-
Leissring, M.A.1
Murphy, M.P.2
Mead, T.R.3
Akbari, Y.4
Sugarman, M.C.5
Jannatipour, M.6
Anliker, B.7
Muller, U.8
Saftig, P.9
De Strooper, B.10
-
22
-
-
34547479273
-
Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content
-
10.1111/j.1471-4159.2007.04627.x. 17763532
-
Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content. R Hamid E Kilger M Willem N Vassallo M Kostka C Bornhovd AS Reichert HA Kretzschmar C Haass J Herms, J Neurochem 2007 102 4 1264 1275 10.1111/j.1471-4159.2007.04627.x 17763532
-
(2007)
J Neurochem
, vol.102
, Issue.4
, pp. 1264-1275
-
-
Hamid, R.1
Kilger, E.2
Willem, M.3
Vassallo, N.4
Kostka, M.5
Bornhovd, C.6
Reichert, A.S.7
Kretzschmar, H.A.8
Haass, C.9
Herms, J.10
-
23
-
-
0345743462
-
Adaptor protein interactions: Modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?
-
10.1016/j.expneurol.2003.10.011. 14736502
-
Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk? GD King R Scott Turner, Exp Neurol 2004 185 2 208 219 10.1016/j.expneurol.2003.10.011 14736502
-
(2004)
Exp Neurol
, vol.185
, Issue.2
, pp. 208-219
-
-
King, G.D.1
Scott Turner, R.2
-
24
-
-
2442498577
-
FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein
-
10.1523/JNEUROSCI.5451-03.2004. 15115822
-
FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein. CU Pietrzik IS Yoon S Jaeger T Busse S Weggen EH Koo, J Neurosci 2004 24 17 4259 4265 10.1523/JNEUROSCI.5451-03.2004 15115822
-
(2004)
J Neurosci
, vol.24
, Issue.17
, pp. 4259-4265
-
-
Pietrzik, C.U.1
Yoon, I.S.2
Jaeger, S.3
Busse, T.4
Weggen, S.5
Koo, E.H.6
-
25
-
-
0036462590
-
Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP)
-
10.1074/jbc.M108357200. 11724784
-
Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP). MH Scheinfeld R Roncarati P Vito PA Lopez M Abdallah L D'Adamio, J Biol Chem 2002 277 5 3767 3775 10.1074/jbc.M108357200 11724784
-
(2002)
J Biol Chem
, vol.277
, Issue.5
, pp. 3767-3775
-
-
Scheinfeld, M.H.1
Roncarati, R.2
Vito, P.3
Lopez, P.A.4
Abdallah, M.5
D'Adamio, L.6
-
26
-
-
0035449943
-
c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK
-
11517249
-
c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK. S Matsuda T Yasukawa Y Homma Y Ito T Niikura T Hiraki S Hirai S Ohno Y Kita M Kawasumi et al., J Neurosci 2001 21 17 6597 6607 11517249
-
(2001)
J Neurosci
, vol.21
, Issue.17
, pp. 6597-6607
-
-
Matsuda, S.1
Yasukawa, T.2
Homma, Y.3
Ito, Y.4
Niikura, T.5
Hiraki, T.6
Hirai, S.7
Ohno, S.8
Kita, Y.9
Kawasumi, M.10
-
27
-
-
0142211267
-
Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1
-
10.1074/jbc.M304853200. 12917434
-
Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1. MH Scheinfeld E Ghersi P Davies L D'Adamio, J Biol Chem 2003 278 43 42058 42063 10.1074/jbc.M304853200 12917434
-
(2003)
J Biol Chem
, vol.278
, Issue.43
, pp. 42058-42063
-
-
Scheinfeld, M.H.1
Ghersi, E.2
Davies, P.3
D'Adamio, L.4
-
28
-
-
0038603918
-
A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1
-
10.1074/jbc.M212160200. 12665528
-
A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. H Inomata Y Nakamura A Hayakawa H Takata T Suzuki K Miyazawa N Kitamura, J Biol Chem 2003 278 25 22946 22955 10.1074/jbc.M212160200 12665528
-
(2003)
J Biol Chem
, vol.278
, Issue.25
, pp. 22946-22955
-
-
Inomata, H.1
Nakamura, Y.2
Hayakawa, A.3
Takata, H.4
Suzuki, T.5
Miyazawa, K.6
Kitamura, N.7
-
29
-
-
0141532147
-
Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1
-
10.1074/jbc.M304379200. 12893827
-
Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1. S Matsuda Y Matsuda L D'Adamio, J Biol Chem 2003 278 40 38601 38606 10.1074/jbc.M304379200 12893827
-
(2003)
J Biol Chem
, vol.278
, Issue.40
, pp. 38601-38606
-
-
Matsuda, S.1
Matsuda, Y.2
D'Adamio, L.3
-
30
-
-
27944444156
-
Coordinated transport of phosphorylated amyloidbeta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1
-
16301330. 10.1083/jcb.200502043
-
Coordinated transport of phosphorylated amyloidbeta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1. Z Muresan V Muresan, J Cell Biol 2005 171 4 615 625 16301330 10.1083/jcb.200502043
-
(2005)
J Cell Biol
, vol.171
, Issue.4
, pp. 615-625
-
-
Muresan, Z.1
Muresan, V.2
-
31
-
-
33947140574
-
Pin1 in Alzheimer's disease: Multiple substrates, one regulatory mechanism?
-
17317113
-
Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism? M Balastik J Lim L Pastorino KP Lu, Biochim Biophys Acta 2007 1772 4 422 429 17317113
-
(2007)
Biochim Biophys Acta
, vol.1772
, Issue.4
, pp. 422-429
-
-
Balastik, M.1
Lim, J.2
Pastorino, L.3
Lu, K.P.4
-
32
-
-
33645300736
-
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production
-
10.1038/nature04543. 16554819
-
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. L Pastorino A Sun PJ Lu XZ Zhou M Balastik G Finn G Wulf J Lim SH Li X Li et al., Nature 2006 440 7083 528 534 10.1038/nature04543 16554819
-
(2006)
Nature
, vol.440
, Issue.7083
, pp. 528-534
-
-
Pastorino, L.1
Sun, A.2
Lu, P.J.3
Zhou, X.Z.4
Balastik, M.5
Finn, G.6
Wulf, G.7
Lim, J.8
Li, S.H.9
Li, X.10
-
33
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
10.1126/science.284.5415.770. 10221902
-
Notch signaling: cell fate control and signal integration in development. S Artavanis-Tsakonas MD Rand RJ Lake, Science 1999 284 5415 770 776 10.1126/science.284.5415.770 10221902
-
(1999)
Science
, vol.284
, Issue.5415
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
34
-
-
0033214675
-
Presenilins: Molecular switches between proteolysis and signal transduction
-
10.1016/S0166-2236(99)01455-1. 10481190
-
Presenilins: molecular switches between proteolysis and signal transduction. W Annaert B De Strooper, Trends Neurosci 1999 22 10 439 443 10.1016/S0166-2236(99)01455-1 10481190
-
(1999)
Trends Neurosci
, vol.22
, Issue.10
, pp. 439-443
-
-
Annaert, W.1
De Strooper, B.2
-
35
-
-
0029598484
-
The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein
-
10.1074/jbc.270.52.30853
-
The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein. F Fiore N Zambrano G Minopoli V Donini A Duilio T Russo, J Biol Chem. 1995 270 52 30853 30856 10.1074/jbc.270.52.30853
-
(1995)
J Biol Chem
, vol.270
, Issue.52
, pp. 30853-30856
-
-
Fiore, F.1
Zambrano, N.2
Minopoli, G.3
Donini, V.4
Duilio, A.5
Russo, T.6
-
36
-
-
0032467640
-
Tip60 acetylates six lysines of a specific class in core histones in vitro
-
10.1046/j.1365-2443.1998.00229.x. 10096020
-
Tip60 acetylates six lysines of a specific class in core histones in vitro. A Kimura M Horikoshi, Genes Cells 1998 3 12 789 800 10.1046/j.1365-2443. 1998.00229.x 10096020
-
(1998)
Genes Cells
, vol.3
, Issue.12
, pp. 789-800
-
-
Kimura, A.1
Horikoshi, M.2
-
37
-
-
21444436589
-
Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET
-
15592452. 10.1038/sj.embor.7400309
-
Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. F Telese P Bruni A Donizetti D Gianni C D'Ambrosio A Scaloni N Zambrano MG Rosenfeld T Russo, EMBO Rep 2005 6 1 77 82 15592452 10.1038/sj.embor.7400309
-
(2005)
EMBO Rep
, vol.6
, Issue.1
, pp. 77-82
-
-
Telese, F.1
Bruni, P.2
Donizetti, A.3
Gianni, D.4
D'Ambrosio, C.5
Scaloni, A.6
Zambrano, N.7
Rosenfeld, M.G.8
Russo, T.9
-
38
-
-
0035909901
-
The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus
-
11742091. 10.1073/pnas.261463298
-
The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus. Y Gao SW Pimplikar, Proc Natl Acad Sci USA 2001 98 26 14979 14984 11742091 10.1073/pnas.261463298
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.26
, pp. 14979-14984
-
-
Gao, Y.1
Pimplikar, S.W.2
-
39
-
-
27544442991
-
Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain
-
16230462. 10.1083/jcb.200505078
-
Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain. KA Ryan SW Pimplikar, J Cell Biol 2005 171 2 327 335 16230462 10.1083/jcb.200505078
-
(2005)
J Cell Biol
, vol.171
, Issue.2
, pp. 327-335
-
-
Ryan, K.A.1
Pimplikar, S.W.2
-
40
-
-
0032410747
-
PAT1, a microtubuleinteracting protein, recognizes the basolateral sorting signal of amyloid precursor protein
-
9843960. 10.1073/pnas.95.25.14745
-
PAT1, a microtubuleinteracting protein, recognizes the basolateral sorting signal of amyloid precursor protein. P Zheng J Eastman S Vande Pol SW Pimplikar, Proc Natl Acad Sci USA 1998 95 25 14745 14750 9843960 10.1073/pnas.95.25.14745
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.25
, pp. 14745-14750
-
-
Zheng, P.1
Eastman, J.2
Pol, S.V.3
Pimplikar, S.W.4
-
41
-
-
10344243551
-
Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway
-
10.1074/jbc.C400396200. 15456788
-
Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway. SH Kim YI Yin YM Li SS Sisodia, J Biol Chem 2004 279 47 48615 48619 10.1074/jbc.C400396200 15456788
-
(2004)
J Biol Chem
, vol.279
, Issue.47
, pp. 48615-48619
-
-
Kim, S.H.1
Yin, Y.I.2
Li, Y.M.3
Sisodia, S.S.4
-
42
-
-
0027333415
-
Signal-dependent membrane protein trafficking in the endocytic pathway
-
10.1146/annurev.cb.09.110193.001021. 8280459
-
Signal-dependent membrane protein trafficking in the endocytic pathway. IS Trowbridge JF Collawn CR Hopkins, Annu Rev Cell Biol 1993 9 129 161 10.1146/annurev.cb.09.110193.001021 8280459
-
(1993)
Annu Rev Cell Biol
, vol.9
, pp. 129-161
-
-
Trowbridge, I.S.1
Collawn, J.F.2
Hopkins, C.R.3
-
43
-
-
2942586693
-
Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain
-
10.1074/jbc.M400488200. 15054097
-
Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain. D Zhou C Noviello C D'Ambrosio A Scaloni L D'Adamio, J Biol Chem 2004 279 24 25374 25380 10.1074/jbc.M400488200 15054097
-
(2004)
J Biol Chem
, vol.279
, Issue.24
, pp. 25374-25380
-
-
Zhou, D.1
Noviello, C.2
D'Ambrosio, C.3
Scaloni, A.4
D'Adamio, L.5
-
44
-
-
0037053281
-
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc
-
10.1074/jbc.M110286200. 11877420
-
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc. PE Tarr R Roncarati G Pelicci PG Pelicci L D'Adamio, J Biol Chem 2002 277 19 16798 16804 10.1074/jbc.M110286200 11877420
-
(2002)
J Biol Chem
, vol.277
, Issue.19
, pp. 16798-16804
-
-
Tarr, P.E.1
Roncarati, R.2
Pelicci, G.3
Pelicci, P.G.4
D'Adamio, L.5
-
45
-
-
60349103104
-
Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling
-
19221419
-
Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling. D Zhou N Zambrano T Russo L D'Adamio, J Alzheimers Dis 2009 16 2 301 307 19221419
-
(2009)
J Alzheimers Dis
, vol.16
, Issue.2
, pp. 301-307
-
-
Zhou, D.1
Zambrano, N.2
Russo, T.3
D'Adamio, L.4
-
46
-
-
0028295848
-
Cell cycledependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein
-
8131745
-
Cell cycledependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein. T Suzuki M Oishi DR Marshak AJ Czernik AC Nairn P Greengard, EMBO J 1994 13 5 1114 1122 8131745
-
(1994)
EMBO J
, vol.13
, Issue.5
, pp. 1114-1122
-
-
Suzuki, T.1
Oishi, M.2
Marshak, D.R.3
Czernik, A.J.4
Nairn, A.C.5
Greengard, P.6
-
47
-
-
0035827587
-
The beta-amyloid precursor protein APP is tyrosinephosphorylated in cells expressing a constitutively active form of the Abl protoncogene
-
10.1074/jbc.M100792200. 11279131
-
The beta-amyloid precursor protein APP is tyrosinephosphorylated in cells expressing a constitutively active form of the Abl protoncogene. N Zambrano P Bruni G Minopoli R Mosca D Molino C Russo G Schettini M Sudol T Russo, J Biol Chem 2001 276 23 19787 19792 10.1074/jbc.M100792200 11279131
-
(2001)
J Biol Chem
, vol.276
, Issue.23
, pp. 19787-19792
-
-
Zambrano, N.1
Bruni, P.2
Minopoli, G.3
Mosca, R.4
Molino, D.5
Russo, C.6
Schettini, G.7
Sudol, M.8
Russo, T.9
-
48
-
-
0030954298
-
The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells
-
9085254
-
The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells. M Oishi AC Nairn AJ Czernik GS Lim T Isohara SE Gandy P Greengard T Suzuki, Mol Med 1997 3 2 111 123 9085254
-
(1997)
Mol Med
, vol.3
, Issue.2
, pp. 111-123
-
-
Oishi, M.1
Nairn, A.C.2
Czernik, A.J.3
Lim, G.S.4
Isohara, T.5
Gandy, S.E.6
Greengard, P.7
Suzuki, T.8
-
49
-
-
0142123260
-
APP processing is regulated by cytoplasmic phosphorylation
-
14557249. 10.1083/jcb.200301115
-
APP processing is regulated by cytoplasmic phosphorylation. MS Lee SC Kao CA Lemere W Xia HC Tseng Y Zhou R Neve MK Ahlijanian LH Tsai, J Cell Biol 2003 163 1 83 95 14557249 10.1083/jcb.200301115
-
(2003)
J Cell Biol
, vol.163
, Issue.1
, pp. 83-95
-
-
Lee, M.S.1
Kao, S.C.2
Lemere, C.A.3
Xia, W.4
Tseng, H.C.5
Zhou, Y.6
Neve, R.7
Ahlijanian, M.K.8
Tsai, L.H.9
-
50
-
-
2542424286
-
Fast anterograde transport of herpes simplex virus: Role for the amyloid precursor protein of alzheimer's disease
-
10.1046/j.1474-9728.2003.00069.x. 14677633
-
Fast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of alzheimer's disease. P Satpute-Krishnan JA DeGiorgis EL Bearer, Aging Cell 2003 2 6 305 318 10.1046/j.1474-9728.2003.00069.x 14677633
-
(2003)
Aging Cell
, vol.2
, Issue.6
, pp. 305-318
-
-
Satpute-Krishnan, P.1
DeGiorgis, J.A.2
Bearer, E.L.3
-
51
-
-
33747033678
-
Pathogenic mechanisms in Alzheimer's disease
-
10.1016/j.ejphar.2006.06.078. 16904664
-
Pathogenic mechanisms in Alzheimer's disease. L Pastorino KP Lu, Eur J Pharmacol 2006 545 1 29 38 10.1016/j.ejphar.2006.06.078 16904664
-
(2006)
Eur J Pharmacol
, vol.545
, Issue.1
, pp. 29-38
-
-
Pastorino, L.1
Lu, K.P.2
-
52
-
-
0037144497
-
Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain
-
10.1074/jbc.M110785200. 12084708
-
Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain. C Russo V Dolcini S Salis V Venezia N Zambrano T Russo G Schettini, J Biol Chem 2002 277 38 35282 35288 10.1074/jbc.M110785200 12084708
-
(2002)
J Biol Chem
, vol.277
, Issue.38
, pp. 35282-35288
-
-
Russo, C.1
Dolcini, V.2
Salis, S.3
Venezia, V.4
Zambrano, N.5
Russo, T.6
Schettini, G.7
-
53
-
-
0032213730
-
Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain
-
10.1016/S0166-2236(98)01282-X. 9829689
-
Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain. E Cattaneo PG Pelicci, Trends Neurosci 1998 21 11 476 481 10.1016/S0166-2236(98)01282-X 9829689
-
(1998)
Trends Neurosci
, vol.21
, Issue.11
, pp. 476-481
-
-
Cattaneo, E.1
Pelicci, P.G.2
-
54
-
-
0028243655
-
Direct interaction between Shc and the platelet-derived growth factor beta-receptor
-
8195171
-
Direct interaction between Shc and the platelet-derived growth factor beta-receptor. K Yokote S Mori K Hansen J McGlade T Pawson CH Heldin L Claesson-Welsh, J Biol Chem 1994 269 21 15337 15343 8195171
-
(1994)
J Biol Chem
, vol.269
, Issue.21
, pp. 15337-15343
-
-
Yokote, K.1
Mori, S.2
Hansen, K.3
McGlade, J.4
Pawson, T.5
Heldin, C.H.6
Claesson-Welsh, L.7
-
55
-
-
85047700252
-
Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis
-
10.1038/sj.onc.1205261. 11896612
-
Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis. C Saucier V Papavasiliou A Palazzo MA Naujokas R Kremer M Park, Oncogene 2002 21 12 1800 1811 10.1038/sj.onc.1205261 11896612
-
(2002)
Oncogene
, vol.21
, Issue.12
, pp. 1800-1811
-
-
Saucier, C.1
Papavasiliou, V.2
Palazzo, A.3
Naujokas, M.A.4
Kremer, R.5
Park, M.6
-
56
-
-
0037452461
-
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
-
12571362. 10.1073/pnas.0336359100
-
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. C Napoli I Martin-Padura F de Nigris M Giorgio G Mansueto P Somma M Condorelli G Sica G De Rosa P Pelicci, Proc Natl Acad Sci USA 2003 100 4 2112 2116 12571362 10.1073/pnas.0336359100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.4
, pp. 2112-2116
-
-
Napoli, C.1
Martin-Padura, I.2
De Nigris, F.3
Giorgio, M.4
Mansueto, G.5
Somma, P.6
Condorelli, M.7
Sica, G.8
De Rosa, G.9
Pelicci, P.10
-
57
-
-
0035137171
-
Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: Implications for human breast cancer
-
11238891. 10.1128/MCB.21.5.1540-1551.2001
-
Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer. D Dankort B Maslikowski N Warner N Kanno H Kim Z Wang MF Moran RG Oshima RD Cardiff WJ Muller, Mol Cell Biol 2001 21 5 1540 1551 11238891 10.1128/MCB.21.5.1540-1551. 2001
-
(2001)
Mol Cell Biol
, vol.21
, Issue.5
, pp. 1540-1551
-
-
Dankort, D.1
Maslikowski, B.2
Warner, N.3
Kanno, N.4
Kim, H.5
Wang, Z.6
Moran, M.F.7
Oshima, R.G.8
Cardiff, R.D.9
Muller, W.J.10
-
58
-
-
51849131587
-
Focal adhesion components are essential for mammalian cell cytokinesis
-
18787414
-
Focal adhesion components are essential for mammalian cell cytokinesis. SH Shafikhani K Mostov J Engel, Cell Cycle 2008 7 18 2868 2876 18787414
-
(2008)
Cell Cycle
, vol.7
, Issue.18
, pp. 2868-2876
-
-
Shafikhani, S.H.1
Mostov, K.2
Engel, J.3
-
59
-
-
0028881018
-
Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G
-
8524240
-
Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G. T Gotoh S Hattori S Nakamura H Kitayama M Noda Y Takai K Kaibuchi H Matsui O Hatase H Takahashi et al., Mol Cell Biol 1995 15 12 6746 6753 8524240
-
(1995)
Mol Cell Biol
, vol.15
, Issue.12
, pp. 6746-6753
-
-
Gotoh, T.1
Hattori, S.2
Nakamura, S.3
Kitayama, H.4
Noda, M.5
Takai, Y.6
Kaibuchi, K.7
Matsui, H.8
Hatase, O.9
Takahashi, H.10
-
60
-
-
0033604512
-
Ras and Rap1: Two highly related small GTPases with distinct function
-
10.1006/excr.1999.4695. 10579920
-
Ras and Rap1: two highly related small GTPases with distinct function. FJ Zwartkruis JL Bos, Exp Cell Res 1999 253 1 157 165 10.1006/excr.1999.4695 10579920
-
(1999)
Exp Cell Res
, vol.253
, Issue.1
, pp. 157-165
-
-
Zwartkruis, F.J.1
Bos, J.L.2
-
61
-
-
0035947724
-
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells
-
10.1074/jbc.M008870200. 11278445
-
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells. S Kao RK Jaiswal W Kolch GE Landreth, J Biol Chem 2001 276 21 18169 18177 10.1074/jbc.M008870200 11278445
-
(2001)
J Biol Chem
, vol.276
, Issue.21
, pp. 18169-18177
-
-
Kao, S.1
Jaiswal, R.K.2
Kolch, W.3
Landreth, G.E.4
-
62
-
-
0036015163
-
The Nck family of adapter proteins: Regulators of actin cytoskeleton
-
10.1016/S0898-6568(02)00027-X. 12034353
-
The Nck family of adapter proteins: regulators of actin cytoskeleton. L Buday L Wunderlich P Tamas, Cell Signal 2002 14 9 723 731 10.1016/S0898-6568(02) 00027-X 12034353
-
(2002)
Cell Signal
, vol.14
, Issue.9
, pp. 723-731
-
-
Buday, L.1
Wunderlich, L.2
Tamas, P.3
-
63
-
-
0034048704
-
Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease
-
10.1006/geno.1999.6053. 10673335
-
Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease. T Suzuki K Nishiyama A Yamamoto J Inazawa T Iwaki T Yamada I Kanazawa Y Sakaki, Genomics 2000 63 2 246 254 10.1006/geno.1999.6053 10673335
-
(2000)
Genomics
, vol.63
, Issue.2
, pp. 246-254
-
-
Suzuki, T.1
Nishiyama, K.2
Yamamoto, A.3
Inazawa, J.4
Iwaki, T.5
Yamada, T.6
Kanazawa, I.7
Sakaki, Y.8
-
64
-
-
0035807755
-
Human Nck-associated protein 1 and its binding protein affect the metabolism of beta-amyloid precursor protein with Swedish mutation
-
10.1016/S0304-3940(01)02370-9. 11720776
-
Human Nck-associated protein 1 and its binding protein affect the metabolism of beta-amyloid precursor protein with Swedish mutation. A Yamamoto C Behl, Neurosci Lett 2001 316 1 50 54 10.1016/S0304-3940(01)02370-9 11720776
-
(2001)
Neurosci Lett
, vol.316
, Issue.1
, pp. 50-54
-
-
Yamamoto, A.1
Behl, C.2
-
65
-
-
2542423595
-
The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling
-
10.1074/jbc.M311479200. 15031292
-
The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling. MS Perkinton CL Standen KF Lau S Kesavapany HL Byers M Ward DM McLoughlin CC Miller, J Biol Chem 2004 279 21 22084 22091 10.1074/jbc.M311479200 15031292
-
(2004)
J Biol Chem
, vol.279
, Issue.21
, pp. 22084-22091
-
-
Perkinton, M.S.1
Standen, C.L.2
Lau, K.F.3
Kesavapany, S.4
Byers, H.L.5
Ward, M.6
McLoughlin, D.M.7
Miller, C.C.8
-
66
-
-
34248203118
-
Src family kinases and lipid mediators in control of allergic inflammation
-
10.1111/j.1600-065X.2007.00505.x. 17498064
-
Src family kinases and lipid mediators in control of allergic inflammation. J Rivera A Olivera, Immunol Rev 2007 217 255 268 10.1111/j.1600-065X.2007.00505.x 17498064
-
(2007)
Immunol Rev
, vol.217
, pp. 255-268
-
-
Rivera, J.1
Olivera, A.2
-
67
-
-
0024869241
-
Function, location, and regulation of the src protein-tyrosine kinase
-
2484925
-
Function, location, and regulation of the src protein-tyrosine kinase. H Varmus H Hirai D Morgan J Kaplan JM Bishop, Princess Takamatsu Symp 1989 20 63 70 2484925
-
(1989)
Princess Takamatsu Symp
, vol.20
, pp. 63-70
-
-
Varmus, H.1
Hirai, H.2
Morgan, D.3
Kaplan, J.4
Bishop, J.M.5
-
68
-
-
33748657133
-
PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling
-
10.1080/13813450600711359. 16931451
-
PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling. M Vinciguerra M Foti, Arch Physiol Biochem 2006 112 2 89 104 10.1080/13813450600711359 16931451
-
(2006)
Arch Physiol Biochem
, vol.112
, Issue.2
, pp. 89-104
-
-
Vinciguerra, M.1
Foti, M.2
-
69
-
-
0032788884
-
Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells
-
10409724
-
Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells. H Kim H Baumann, Mol Cell Biol 1999 19 8 5326 5338 10409724
-
(1999)
Mol Cell Biol
, vol.19
, Issue.8
, pp. 5326-5338
-
-
Kim, H.1
Baumann, H.2
-
70
-
-
30944456676
-
The latest phospholipase C, PLCeta, is implicated in neuronal function
-
10.1016/j.tibs.2005.11.003. 16310357
-
The latest phospholipase C, PLCeta, is implicated in neuronal function. S Cockcroft, Trends Biochem Sci 2006 31 1 4 7 10.1016/j.tibs.2005.11.003 16310357
-
(2006)
Trends Biochem Sci
, vol.31
, Issue.1
, pp. 4-7
-
-
Cockcroft, S.1
-
71
-
-
0037205493
-
Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade
-
10.1074/jbc.M108372200. 11912189
-
Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. H Taru K Iijima M Hase Y Kirino Y Yagi T Suzuki, J Biol Chem 2002 277 22 20070 20078 10.1074/jbc.M108372200 11912189
-
(2002)
J Biol Chem
, vol.277
, Issue.22
, pp. 20070-20078
-
-
Taru, H.1
Iijima, K.2
Hase, M.3
Kirino, Y.4
Yagi, Y.5
Suzuki, T.6
-
73
-
-
0032508714
-
A mammalian scaffold complex that selectively mediates MAP kinase activation
-
10.1126/science.281.5383.1671. 9733513
-
A mammalian scaffold complex that selectively mediates MAP kinase activation. AJ Whitmarsh J Cavanagh C Tournier J Yasuda RJ Davis, Science 1998 281 5383 1671 1674 10.1126/science.281.5383.1671 9733513
-
(1998)
Science
, vol.281
, Issue.5383
, pp. 1671-1674
-
-
Whitmarsh, A.J.1
Cavanagh, J.2
Tournier, C.3
Yasuda, J.4
Davis, R.J.5
-
74
-
-
0030826412
-
A cytoplasmic inhibitor of the JNK signal transduction pathway
-
10.1126/science.277.5326.693. 9235893
-
A cytoplasmic inhibitor of the JNK signal transduction pathway. M Dickens JS Rogers J Cavanagh A Raitano Z Xia JR Halpern ME Greenberg CL Sawyers RJ Davis, Science 1997 277 5326 693 696 10.1126/science.277.5326.693 9235893
-
(1997)
Science
, vol.277
, Issue.5326
, pp. 693-696
-
-
Dickens, M.1
Rogers, J.S.2
Cavanagh, J.3
Raitano, A.4
Xia, Z.5
Halpern, J.R.6
Greenberg, M.E.7
Sawyers, C.L.8
Davis, R.J.9
-
75
-
-
0033066680
-
The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids
-
10373567
-
The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids. BW Howell LM Lanier R Frank FB Gertler JA Cooper, Mol Cell Biol 1999 19 7 5179 5188 10373567
-
(1999)
Mol Cell Biol
, vol.19
, Issue.7
, pp. 5179-5188
-
-
Howell, B.W.1
Lanier, L.M.2
Frank, R.3
Gertler, F.B.4
Cooper, J.A.5
-
76
-
-
0033198295
-
Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1
-
10460257
-
Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1. R Homayouni DS Rice M Sheldon T Curran, J Neurosci 1999 19 17 7507 7515 10460257
-
(1999)
J Neurosci
, vol.19
, Issue.17
, pp. 7507-7515
-
-
Homayouni, R.1
Rice, D.S.2
Sheldon, M.3
Curran, T.4
-
77
-
-
0033556251
-
Cutting edge: Protective effects of notch-1 on TCR-induced apoptosis
-
9916679
-
Cutting edge: protective effects of notch-1 on TCR-induced apoptosis. BM Jehn W Bielke WS Pear BA Osborne, J Immunol 1999 162 2 635 638 9916679
-
(1999)
J Immunol
, vol.162
, Issue.2
, pp. 635-638
-
-
Jehn, B.M.1
Bielke, W.2
Pear, W.S.3
Osborne, B.A.4
-
78
-
-
54449093012
-
Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: Implications for Alzheimer disease pathogenesis
-
10.1074/jbc.M802072200. 18599481
-
Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis. GA Kyriazis Z Wei M Vandermey DG Jo O Xin MP Mattson SL Chan, J Biol Chem 2008 283 37 25492 25502 10.1074/jbc.M802072200 18599481
-
(2008)
J Biol Chem
, vol.283
, Issue.37
, pp. 25492-25502
-
-
Kyriazis, G.A.1
Wei, Z.2
Vandermey, M.3
Jo, D.G.4
Xin, O.5
Mattson, M.P.6
Chan, S.L.7
-
79
-
-
0032510834
-
The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion
-
10.1074/jbc.273.24.14761. 9614075
-
The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. JP Borg Y Yang M De Taddeo-Borg B Margolis RS Turner, J Biol Chem 1998 273 24 14761 14766 10.1074/jbc.273.24.14761 9614075
-
(1998)
J Biol Chem
, vol.273
, Issue.24
, pp. 14761-14766
-
-
Borg, J.P.1
Yang, Y.2
De Taddeo-Borg, M.3
Margolis, B.4
Turner, R.S.5
-
80
-
-
0029805132
-
The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein
-
8887653
-
The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. JP Borg J Ooi E Levy B Margolis, Mol Cell Biol 1996 16 11 6229 6241 8887653
-
(1996)
Mol Cell Biol
, vol.16
, Issue.11
, pp. 6229-6241
-
-
Borg, J.P.1
Ooi, J.2
Levy, E.3
Margolis, B.4
-
81
-
-
0034603030
-
Synaptic assembly of the brain in the absence of neurotransmitter secretion
-
10.1126/science.287.5454.864. 10657302
-
Synaptic assembly of the brain in the absence of neurotransmitter secretion. M Verhage AS Maia JJ Plomp AB Brussaard JH Heeroma H Vermeer RF Toonen RE Hammer TK van den Berg M Missler et al., Science 2000 287 5454 864 869 10.1126/science.287.5454.864 10657302
-
(2000)
Science
, vol.287
, Issue.5454
, pp. 864-869
-
-
Verhage, M.1
Maia, A.S.2
Plomp, J.J.3
Brussaard, A.B.4
Heeroma, J.H.5
Vermeer, H.6
Toonen, R.F.7
Hammer, R.E.8
Van Den Berg, T.K.9
Missler, M.10
-
82
-
-
33846613222
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
-
17220890. 10.1038/ng1943
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. E Rogaeva Y Meng JH Lee Y Gu T Kawarai F Zou T Katayama CT Baldwin R Cheng H Hasegawa et al., Nat Genet 2007 39 2 168 177 17220890 10.1038/ng1943
-
(2007)
Nat Genet
, vol.39
, Issue.2
, pp. 168-177
-
-
Rogaeva, E.1
Meng, Y.2
Lee, J.H.3
Gu, Y.4
Kawarai, T.5
Zou, F.6
Katayama, T.7
Baldwin, C.T.8
Cheng, R.9
Hasegawa, H.10
-
83
-
-
0033638180
-
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
-
10.1016/S1097-2765(05)00083-3. 11090625
-
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins. XZ Zhou O Kops A Werner PJ Lu M Shen G Stoller G Kullertz M Stark G Fischer KP Lu, Mol Cell 2000 6 4 873 883 10.1016/S1097-2765(05)00083-3 11090625
-
(2000)
Mol Cell
, vol.6
, Issue.4
, pp. 873-883
-
-
Zhou, X.Z.1
Kops, O.2
Werner, A.3
Lu, P.J.4
Shen, M.5
Stoller, G.6
Kullertz, G.7
Stark, M.8
Fischer, G.9
Lu, K.P.10
-
84
-
-
34247867974
-
Association studies between common variants in prolyl isomerase Pin1 and the risk for late-onset Alzheimer's disease
-
17482359. 10.1016/j.neulet.2007.03.071
-
Association studies between common variants in prolyl isomerase Pin1 and the risk for late-onset Alzheimer's disease. P Nowotny S Bertelsen AL Hinrichs JS Kauwe K Mayo S Jacquart JC Morris A Goate, Neurosci Lett 2007 419 1 15 17 17482359 10.1016/j.neulet.2007.03.071
-
(2007)
Neurosci Lett
, vol.419
, Issue.1
, pp. 15-17
-
-
Nowotny, P.1
Bertelsen, S.2
Hinrichs, A.L.3
Kauwe, J.S.4
Mayo, K.5
Jacquart, S.6
Morris, J.C.7
Goate, A.8
-
85
-
-
0042203565
-
SH2 and PTB domains in tyrosine kinase signaling
-
10.1126/stke.2003.191.re12. 12865499
-
SH2 and PTB domains in tyrosine kinase signaling. J Schlessinger MA Lemmon, Sci STKE 2003 2003 191 RE12 10.1126/stke.2003.191.re12 12865499
-
(2003)
Sci STKE
, vol.2003
, Issue.191
-
-
Schlessinger, J.1
Lemmon, M.A.2
-
86
-
-
0035118308
-
Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain
-
10.1006/nbdi.2000.0357. 11162251
-
Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain. C Russo S Salis V Dolcini V Venezia XH Song JK Teller G Schettini, Neurobiol Dis 2001 8 1 173 180 10.1006/nbdi.2000.0357 11162251
-
(2001)
Neurobiol Dis
, vol.8
, Issue.1
, pp. 173-180
-
-
Russo, C.1
Salis, S.2
Dolcini, V.3
Venezia, V.4
Song, X.H.5
Teller, J.K.6
Schettini, G.7
-
87
-
-
15944366164
-
Interaction of Tau with Fe65 links tau to APP
-
10.1016/j.nbd.2004.10.011. 15686969
-
Interaction of Tau with Fe65 links tau to APP. C Barbato N Canu N Zambrano A Serafino G Minopoli MT Ciotti G Amadoro T Russo P Calissano, Neurobiol Dis 2005 18 2 399 408 10.1016/j.nbd.2004.10.011 15686969
-
(2005)
Neurobiol Dis
, vol.18
, Issue.2
, pp. 399-408
-
-
Barbato, C.1
Canu, N.2
Zambrano, N.3
Serafino, A.4
Minopoli, G.5
Ciotti, M.T.6
Amadoro, G.7
Russo, T.8
Calissano, P.9
-
88
-
-
17844399784
-
The amyloid precursor protein and its network of interacting proteins: Physiological and pathological implications
-
10.1016/j.brainresrev.2004.12.016. 15850665
-
The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications. C Russo V Venezia E Repetto M Nizzari E Violani P Carlo G Schettini, Brain Res Brain Res Rev 2005 48 2 257 264 10.1016/j.brainresrev.2004.12.016 15850665
-
(2005)
Brain Res Brain Res Rev
, vol.48
, Issue.2
, pp. 257-264
-
-
Russo, C.1
Venezia, V.2
Repetto, E.3
Nizzari, M.4
Violani, E.5
Carlo, P.6
Schettini, G.7
-
89
-
-
51849128358
-
Class I PI3K in oncogenic cellular transformation
-
10.1038/onc.2008.244. 18794883
-
Class I PI3K in oncogenic cellular transformation. L Zhao PK Vogt, Oncogene 2008 27 41 5486 5496 10.1038/onc.2008.244 18794883
-
(2008)
Oncogene
, vol.27
, Issue.41
, pp. 5486-5496
-
-
Zhao, L.1
Vogt, P.K.2
-
90
-
-
0032937828
-
Cycling, stressed-out and nervous: Cellular functions of c-Abl
-
10.1016/S0962-8924(99)01549-4. 10322452
-
Cycling, stressed-out and nervous: cellular functions of c-Abl. RA Van Etten, Trends Cell Biol 1999 9 5 179 186 10.1016/S0962-8924(99)01549-4 10322452
-
(1999)
Trends Cell Biol
, vol.9
, Issue.5
, pp. 179-186
-
-
Van Etten, R.A.1
-
91
-
-
0034064630
-
c-Abl: Activation and nuclear targets
-
10.1038/sj.cdd.4400626. 10713716
-
c-Abl: activation and nuclear targets. Y Shaul, Cell Death Differ 2000 7 1 10 16 10.1038/sj.cdd.4400626 10713716
-
(2000)
Cell Death Differ
, vol.7
, Issue.1
, pp. 10-16
-
-
Shaul, Y.1
-
92
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
10.1038/372739a0. 7997261
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. JC Lee JT Laydon PC McDonnell TF Gallagher S Kumar D Green D McNulty MJ Blumenthal JR Heys SW Landvatter et al., Nature 1994 372 6508 739 746 10.1038/372739a0 7997261
-
(1994)
Nature
, vol.372
, Issue.6508
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
93
-
-
0032587404
-
The engagement of beta1 integrins on promonocytic cells promotes phosphorylation of Syk and formation of a protein complex containing Lyn and beta1 integrin
-
10.1002/(SICI)1521-4141(199905)29:05〈1426::AID-IMMU1426〉3.0. CO;2-J. 10359096
-
The engagement of beta1 integrins on promonocytic cells promotes phosphorylation of Syk and formation of a protein complex containing Lyn and beta1 integrin. LA Miller JJ Hong MS Kinch ML Harrison RL Geahlen, Eur J Immunol 1999 29 5 1426 1434 10.1002/(SICI)1521-4141(199905)29:05〈1426::AID- IMMU1426〉3.0.CO;2-J 10359096
-
(1999)
Eur J Immunol
, vol.29
, Issue.5
, pp. 1426-1434
-
-
Miller, L.A.1
Hong, J.J.2
Kinch, M.S.3
Harrison, M.L.4
Geahlen, R.L.5
-
94
-
-
0029005762
-
Integrinmediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase
-
10.1074/jbc.270.27.16189. 7541794
-
Integrinmediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase. TH Lin C Rosales K Mondal JB Bolen S Haskill RL Juliano, J Biol Chem 1995 270 27 16189 16197 10.1074/jbc.270.27.16189 7541794
-
(1995)
J Biol Chem
, vol.270
, Issue.27
, pp. 16189-16197
-
-
Lin, T.H.1
Rosales, C.2
Mondal, K.3
Bolen, J.B.4
Haskill, S.5
Juliano, R.L.6
-
95
-
-
1842689293
-
Amyloid precursor protein mediates proinflammatory activation of monocytic lineage cells
-
10.1074/jbc.M313747200. 14732706
-
Amyloid precursor protein mediates proinflammatory activation of monocytic lineage cells. CM Sondag CK Combs, J Biol Chem 2004 279 14 14456 14463 10.1074/jbc.M313747200 14732706
-
(2004)
J Biol Chem
, vol.279
, Issue.14
, pp. 14456-14463
-
-
Sondag, C.M.1
Combs, C.K.2
-
96
-
-
0028878979
-
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development
-
10.1016/0092-8674(95)90498-0. 7859288
-
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development. TL Tang RM Freeman Jr AM O'Reilly BG Neel SY Sokol, Cell 1995 80 3 473 483 10.1016/0092-8674(95)90498-0 7859288
-
(1995)
Cell
, vol.80
, Issue.3
, pp. 473-483
-
-
Tang, T.L.1
Freeman Jr., R.M.2
O'Reilly, A.M.3
Neel, B.G.4
Sokol, S.Y.5
-
97
-
-
0028123457
-
A new function for a phosphotyrosine phosphatase: Linking GRB2-Sos to a receptor tyrosine kinase
-
8264620
-
A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase. W Li R Nishimura A Kashishian AG Batzer WJ Kim JA Cooper J Schlessinger, Mol Cell Biol 1994 14 1 509 517 8264620
-
(1994)
Mol Cell Biol
, vol.14
, Issue.1
, pp. 509-517
-
-
Li, W.1
Nishimura, R.2
Kashishian, A.3
Batzer, A.G.4
Kim, W.J.5
Cooper, J.A.6
Schlessinger, J.7
-
98
-
-
0033578719
-
Glycosylphosphatidylinositolanchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein
-
10.1074/jbc.274.38.26810. 10480887
-
Glycosylphosphatidylinositolanchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein. K Sambamurti D Sevlever T Koothan LM Refolo I Pinnix S Gandhi L Onstead L Younkin CM Prada D Yager et al., J Biol Chem 1999 274 38 26810 26814 10.1074/jbc.274.38.26810 10480887
-
(1999)
J Biol Chem
, vol.274
, Issue.38
, pp. 26810-26814
-
-
Sambamurti, K.1
Sevlever, D.2
Koothan, T.3
Refolo, L.M.4
Pinnix, I.5
Gandhi, S.6
Onstead, L.7
Younkin, L.8
Prada, C.M.9
Yager, D.10
-
99
-
-
34447309716
-
Presenilin dependence of phospholipase C and protein kinase C signaling
-
10.1111/j.1471-4159.2007.04571.x. 17437536
-
Presenilin dependence of phospholipase C and protein kinase C signaling. N Dehvari A Cedazo-Minguez O Isacsson T Nilsson B Winblad H Karlstrom E Benedikz RF Cowburn, J Neurochem 2007 102 3 848 857 10.1111/j.1471-4159.2007.04571.x 17437536
-
(2007)
J Neurochem
, vol.102
, Issue.3
, pp. 848-857
-
-
Dehvari, N.1
Cedazo-Minguez, A.2
Isacsson, O.3
Nilsson, T.4
Winblad, B.5
Karlstrom, H.6
Benedikz, E.7
Cowburn, R.F.8
-
100
-
-
0037178872
-
Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism
-
10.1074/jbc.M203713200. 12023290
-
Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism. H Taru Y Kirino T Suzuki, J Biol Chem 2002 277 30 27567 27574 10.1074/jbc.M203713200 12023290
-
(2002)
J Biol Chem
, vol.277
, Issue.30
, pp. 27567-27574
-
-
Taru, H.1
Kirino, Y.2
Suzuki, T.3
-
101
-
-
10344247703
-
Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner
-
10.1074/jbc.M405329200. 15347684
-
Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner. E Ghersi C Noviello L D'Adamio, J Biol Chem 2004 279 47 49105 49112 10.1074/jbc.M405329200 15347684
-
(2004)
J Biol Chem
, vol.279
, Issue.47
, pp. 49105-49112
-
-
Ghersi, E.1
Noviello, C.2
D'Adamio, L.3
-
102
-
-
0042357124
-
Autosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor protein
-
10.1074/jbc.M304133200. 12805363
-
Autosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor protein. C Noviello P Vito P Lopez M Abdallah L D'Adamio, J Biol Chem 2003 278 34 31843 31847 10.1074/jbc.M304133200 12805363
-
(2003)
J Biol Chem
, vol.278
, Issue.34
, pp. 31843-31847
-
-
Noviello, C.1
Vito, P.2
Lopez, P.3
Abdallah, M.4
D'Adamio, L.5
-
103
-
-
0035906961
-
Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein
-
10.1126/science.1060458. 11326085
-
Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein. CK Garcia K Wilund M Arca G Zuliani R Fellin M Maioli S Calandra S Bertolini F Cossu N Grishin et al., Science 2001 292 5520 1394 1398 10.1126/science.1060458 11326085
-
(2001)
Science
, vol.292
, Issue.5520
, pp. 1394-1398
-
-
Garcia, C.K.1
Wilund, K.2
Arca, M.3
Zuliani, G.4
Fellin, R.5
Maioli, M.6
Calandra, S.7
Bertolini, S.8
Cossu, F.9
Grishin, N.10
-
104
-
-
0036470472
-
Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion
-
11823414. 10.1093/emboj/21.3.211
-
Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion. F Rosenbauer A Kallies M Scheller KP Knobeloch CO Rock M Schwieger C Stocking I Horak, EMBO J 2002 21 3 211 220 11823414 10.1093/emboj/21.3.211
-
(2002)
EMBO J
, vol.21
, Issue.3
, pp. 211-220
-
-
Rosenbauer, F.1
Kallies, A.2
Scheller, M.3
Knobeloch, K.P.4
Rock, C.O.5
Schwieger, M.6
Stocking, C.7
Horak, I.8
-
105
-
-
0037119952
-
Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor
-
12234931. 10.1093/emboj/cdf487
-
Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor. SK Mishra PA Keyel MJ Hawryluk NR Agostinelli SC Watkins LM Traub, EMBO J 2002 21 18 4915 4926 12234931 10.1093/emboj/cdf487
-
(2002)
EMBO J
, vol.21
, Issue.18
, pp. 4915-4926
-
-
Mishra, S.K.1
Keyel, P.A.2
Hawryluk, M.J.3
Agostinelli, N.R.4
Watkins, S.C.5
Traub, L.M.6
-
106
-
-
0036363731
-
Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: Implications for neuronal death in Alzheimer's disease
-
10.1385/NMM:1:1:55. 12025816
-
Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: implications for neuronal death in Alzheimer's disease. SL Chan WA Pedersen H Zhu MP Mattson, Neuromolecular Med 2002 1 1 55 67 10.1385/NMM:1:1:55 12025816
-
(2002)
Neuromolecular Med
, vol.1
, Issue.1
, pp. 55-67
-
-
Chan, S.L.1
Pedersen, W.A.2
Zhu, H.3
Mattson, M.P.4
-
107
-
-
0034612380
-
Mouse numb is an essential gene involved in cortical neurogenesis
-
10841580. 10.1073/pnas.97.12.6844
-
Mouse numb is an essential gene involved in cortical neurogenesis. W Zhong MM Jiang MD Schonemann JJ Meneses RA Pedersen LY Jan YN Jan, Proc Natl Acad Sci USA 2000 97 12 6844 6849 10841580 10.1073/pnas.97.12.6844
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.12
, pp. 6844-6849
-
-
Zhong, W.1
Jiang, M.M.2
Schonemann, M.D.3
Meneses, J.J.4
Pedersen, R.A.5
Jan, L.Y.6
Jan, Y.N.7
-
108
-
-
0030199973
-
Control of daughter cell fates during asymmetric division: Interaction of Numb and Notch
-
10.1016/S0896-6273(00)80278-0. 8755476
-
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. M Guo LY Jan YN Jan, Neuron 1996 17 1 27 41 10.1016/S0896-6273(00)80278-0 8755476
-
(1996)
Neuron
, vol.17
, Issue.1
, pp. 27-41
-
-
Guo, M.1
Jan, L.Y.2
Jan, Y.N.3
-
109
-
-
0344012486
-
The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice
-
10.1074/jbc.M300503200. 12970358
-
The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice. JH Lee KF Lau MS Perkinton CL Standen SJ Shemilt L Mercken JD Cooper DM McLoughlin CC Miller, J Biol Chem 2003 278 47 47025 47029 10.1074/jbc.M300503200 12970358
-
(2003)
J Biol Chem
, vol.278
, Issue.47
, pp. 47025-47029
-
-
Lee, J.H.1
Lau, K.F.2
Perkinton, M.S.3
Standen, C.L.4
Shemilt, S.J.5
Mercken, L.6
Cooper, J.D.7
McLoughlin, D.M.8
Miller, C.C.9
-
110
-
-
0033593480
-
Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein
-
10.1074/jbc.274.4.2243. 9890987
-
Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein. S Tomita T Ozaki H Taru S Oguchi S Takeda Y Yagi S Sakiyama Y Kirino T Suzuki, J Biol Chem 1999 274 4 2243 2254 10.1074/jbc.274.4.2243 9890987
-
(1999)
J Biol Chem
, vol.274
, Issue.4
, pp. 2243-2254
-
-
Tomita, S.1
Ozaki, T.2
Taru, H.3
Oguchi, S.4
Takeda, S.5
Yagi, Y.6
Sakiyama, S.7
Kirino, Y.8
Suzuki, T.9
-
111
-
-
0032575559
-
X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion
-
10.1074/jbc.273.35.22351. 9712855
-
X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion. M Sastre RS Turner E Levy, J Biol Chem 1998 273 35 22351 22357 10.1074/jbc.273.35.22351 9712855
-
(1998)
J Biol Chem
, vol.273
, Issue.35
, pp. 22351-22357
-
-
Sastre, M.1
Turner, R.S.2
Levy, E.3
-
112
-
-
0030592773
-
The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system
-
10.1016/S0014-5793(96)01128-3. 8955346
-
The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system. DM McLoughlin CC Miller, FEBS Lett 1996 397 2-3 197 200 10.1016/S0014-5793(96)01128-3 8955346
-
(1996)
FEBS Lett
, vol.397
, Issue.2-3
, pp. 197-200
-
-
McLoughlin, D.M.1
Miller, C.C.2
-
113
-
-
0034625631
-
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport
-
10.1126/science.288.5472.1796. 10846156
-
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. M Setou T Nakagawa DH Seog N Hirokawa, Science 2000 288 5472 1796 1802 10.1126/science.288.5472.1796 10846156
-
(2000)
Science
, vol.288
, Issue.5472
, pp. 1796-1802
-
-
Setou, M.1
Nakagawa, T.2
Seog, D.H.3
Hirokawa, N.4
-
114
-
-
0032544613
-
A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain
-
10.1016/S0092-8674(00)81736-5. 9753324
-
A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. S Butz M Okamoto TC Sudhof, Cell 1998 94 6 773 782 10.1016/S0092-8674(00)81736-5 9753324
-
(1998)
Cell
, vol.94
, Issue.6
, pp. 773-782
-
-
Butz, S.1
Okamoto, M.2
Sudhof, T.C.3
-
115
-
-
0033006807
-
Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease
-
10.1046/j.1460-9568.1999.00610.x. 10336668
-
Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease. DM McLoughlin NG Irving J Brownlees JP Brion K Leroy CC Miller, Eur J Neurosci 1999 11 6 1988 1994 10.1046/j.1460-9568.1999.00610.x 10336668
-
(1999)
Eur J Neurosci
, vol.11
, Issue.6
, pp. 1988-1994
-
-
McLoughlin, D.M.1
Irving, N.G.2
Brownlees, J.3
Brion, J.P.4
Leroy, K.5
Miller, C.C.6
-
116
-
-
0346435147
-
X11alpha impairs gamma-but not betacleavage of amyloid precursor protein
-
14756819
-
X11alpha impairs gamma-but not betacleavage of amyloid precursor protein. GD King K Cherian RS Turner, J Neurochem 2004 88 4 971 982 14756819
-
(2004)
J Neurochem
, vol.88
, Issue.4
, pp. 971-982
-
-
King, G.D.1
Cherian, K.2
Turner, R.S.3
-
117
-
-
0036064769
-
Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP
-
10.1016/S0006-291X(02)00678-2. 12150951
-
Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. PE Tarr C Contursi R Roncarati C Noviello E Ghersi MH Scheinfeld N Zambrano T Russo L D'Adamio, Biochem Biophys Res Commun 2002 295 2 324 329 10.1016/S0006-291X(02)00678-2 12150951
-
(2002)
Biochem Biophys Res Commun
, vol.295
, Issue.2
, pp. 324-329
-
-
Tarr, P.E.1
Contursi, C.2
Roncarati, R.3
Noviello, C.4
Ghersi, E.5
Scheinfeld, M.H.6
Zambrano, N.7
Russo, T.8
D'Adamio, L.9
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