-
3
-
-
0031954313
-
Neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer
-
Toronto Breast Cancer Study Group
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 1340-1349
-
-
Andrulis, I.L.1
Bull, S.B.2
Blackstein, M.E.3
Sutherland, D.4
Mak, C.5
Sidlofsky, S.6
Pritzker, K.P.7
Hartwick, R.W.8
Hanna, W.9
Lickley, L.10
Wilkinson, R.11
Qizilbash, A.12
Ambus, U.13
Lipa, M.14
Weizel, H.15
Katz, A.16
Baida, M.17
Mariz, S.18
Stoik, G.19
Dacamara, P.20
Strongitharm, D.21
Geddie, W.22
McCready, D.23
more..
-
4
-
-
0032823487
-
Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer
-
(1999)
Semin. Oncol.
, vol.26
, pp. 78-83
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
Rosen, P.P.11
Twaddell, T.12
Henderson, I.C.13
Norton, L.14
-
7
-
-
0032438571
-
Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation
-
(1998)
Cell
, vol.95
, pp. 793-803
-
-
Cheng, A.M.1
Saxton, T.M.2
Sakai, R.3
Kulkarni, S.4
Mbamalu, G.5
Vogel, W.6
Tortorice, C.G.7
Cardiff, R.D.8
Cross, J.C.9
Muller, W.J.10
Pawson, T.11
-
14
-
-
0029932755
-
Oneogenic Neu/ ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 7992-7998
-
-
Galang, C.K.1
Garcia-Ramirez, J.2
Solski, P.A.3
Westwick, J.K.4
Der, C.J.5
Neznanov, N.N.6
Oshima, R.G.7
Hauser, C.A.8
-
16
-
-
0029910522
-
A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3
-
(1996)
EMBO J.
, vol.15
, pp. 6197-6204
-
-
Gotoh, N.1
Tojo, A.2
Shibuya, M.3
-
17
-
-
0030899807
-
Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activatecl protein kinase activation
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1824-1831
-
-
Gotoh, N.1
Toyoda, M.2
Shibuya, M.3
-
22
-
-
0033553561
-
Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14376-14381
-
-
Ichiba, T.1
Hashimoto, Y.2
Nakaya, M.3
Kuraishi, Y.4
Tanaka, S.5
Kurata, T.6
Mochizuki, N.7
Matsuda, M.8
-
25
-
-
0026726820
-
Reversion of middle T antigen-transformed Rat-2 cells by Krev-1: Implications for the role of p21c-ras in polyomavirus-mediated transformation
-
(1992)
Oncogene
, vol.7
, pp. 1687-1698
-
-
Jelinek, M.A.1
Hassell, J.A.2
-
27
-
-
0028174305
-
Involvement of pp60c-src with two major signaling pathways in human breast cancer
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 83-87
-
-
Luttrell, D.K.1
Lee, A.2
Lansing, T.J.3
Crosby, R.M.4
Jung, K.D.5
Willard, D.6
Luther, M.7
Rodriguez, M.8
Berman, J.9
Gilmer, T.M.10
-
31
-
-
0028808080
-
Activation of Src family kinases in Neu-induced mammary tumors correlates with their association with distinct sets of tyrosine phosphorylated proteins in vivo
-
(1995)
Oncogene
, vol.11
, pp. 1801-1810
-
-
Muthuswamy, S.K.1
Muller, W.J.2
-
33
-
-
0029165834
-
Direct and specific interaction of c-Src with Neu is involved in signaling by the epidermal growth factor receptor
-
(1995)
Oncogene
, vol.11
, pp. 271-279
-
-
Muthuswamy, S.K.1
Muller, W.J.2
-
36
-
-
0028859279
-
Protein modules and signalling networks
-
(1995)
Nature
, vol.373
, pp. 573-580
-
-
Pawson, T.1
-
37
-
-
0028806256
-
Analysis of protein-protein interactions involved in the activation of the Sbc/Grb-2 pathway by the ErbB-2 kinase
-
(1995)
Oncogene
, vol.11
, pp. 1519-1529
-
-
Ricci, A.1
Lanfrancone, L.2
Chiari, R.3
Belardo, G.4
Pertica, C.5
Natali, P.G.6
Pelicci, P.G.7
Segatto, O.8
-
38
-
-
0026757356
-
smg/rap1/Krev-1 p21s inhibit the signal pathway to the c-fos promoter/enhancer from c-Ki-ras p21 but not from c-raf-1 kinase in NIH3T3 cells
-
(1992)
Oncogene
, vol.7
, pp. 1705-1711
-
-
Sakoda, T.1
Kaibuchi, K.2
Kishi, K.3
Kishida, S.4
Doi, K.5
Hoshino, M.6
Hattori, S.7
Takai, Y.8
-
40
-
-
0025757238
-
erb-2 determine the specificity of signal transduction
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 3191-3202
-
-
Segatto, O.1
Lonardo, F.2
Wexler, D.3
Fazioli, F.4
Pierce, J.H.5
Bottaro, D.P.6
White, M.F.7
Di Fiore, P.P.8
-
41
-
-
0027165366
-
Shc products are substrates of erbB-2 kinase
-
(1993)
Oncogene
, vol.8
, pp. 2105-2112
-
-
Segatto, O.1
Pelicci, G.2
Giuli, S.3
Digiesi, G.4
Di Fiore, P.P.5
McGlade, J.6
Pawson, T.7
Pelicci, P.G.8
-
45
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovaian cancer
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
Press, M.F.11
-
46
-
-
0028343550
-
The SH2 protein GRB7 is coamplified, overexpressed and in a tight complex with HER2 in breast cancer
-
(1994)
EMBO J.
, vol.13
, pp. 1331-1340
-
-
Stein, D.1
Wu, J.2
Fuqua, S.A.3
Roonprapaunt, C.4
Yajnik, V.5
D'Eutachio, P.6
Moskow, J.J.7
Buchberg, A.M.8
Osborne, C.K.9
Margolis, B.10
-
47
-
-
0030022174
-
Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation
-
(1996)
EMBO J.
, vol.15
, pp. 810-816
-
-
Urano, T.1
Emkey, R.2
Feig, L.A.3
-
48
-
-
0027211693
-
Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
-
(1993)
Cell
, vol.73
, pp. 321-334
-
-
Valius, M.1
Kazlauskas, A.2
-
52
-
-
0030036079
-
Requirement for the adapter protein GRB2 in EGF receptor endocytosis
-
(1996)
Science
, vol.272
, pp. 1935-1939
-
-
Wang, Z.1
Moran, M.F.2
-
54
-
-
0031948388
-
Requirement for both Shc and phosphatidylinositol 3′kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2344-2359
-
-
Webster, M.A.1
Hutchinson, J.N.2
Rauh, M.J.3
Muthuswamy, S.K.4
Anton, M.5
Tortorice, C.G.6
Cardiff, R.D.7
Graham, F.L.8
Hassell, J.A.9
Muller, W.J.10
-
55
-
-
0032079317
-
Defective trophoblast function in mice with a targeted mutation of Ets2
-
(1998)
Genes Dev.
, vol.12
, pp. 1315-1326
-
-
Yamamoto, H.1
Flannery, M.L.2
Kupriyanov, S.3
Pearce, J.4
McKercher, S.R.5
Henkel, G.W.6
Maki, R.A.7
Werb, Z.8
Oshima, R.G.9
-
56
-
-
0030048767
-
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 538-547
-
-
Yang, B.S.1
Hauser, C.A.2
Henkel, G.3
Colman, M.S.4
Van Beveren, C.5
Stacey, K.J.6
Hume, D.A.7
Maki, R.A.8
Ostrowski, M.C.9
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