Association studies between common variants in prolyl isomerase Pin1 and the risk for late-onset Alzheimer's disease

Neuroscience Letters

Volumn 419, Issue 1, 2007, Pages 15-17

  Nowotny, Petra ^a   Bertelsen, Sarah ^a   Hinrichs, Anthony L ^a   Kauwe, John S K ^a   Mayo, Kevin ^a   Jacquart, Sarah ^a   Morris, John C ^a   Goate, Alison ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Genotyping; Late onset Alzheimer's disease; Pin1

Indexed keywords

PEPTIDYLPROLYL ISOMERASE PIN1;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; LATE ONSET ALZHEIMER DISEASE; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; FEMALE; HUMANS; MALE; META-ANALYSIS; MIDDLE AGED; PEPTIDYLPROLYL ISOMERASE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 34247867974     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.03.071     Document Type: Article

References (10)

1. Lambert J.C., Bensemain F., Chapuis J., Cottel D., and Amouyel P. Association study of the PIN1 gene with Alzheimer's disease. Neurosci. Lett. 402 3 (2006) 259-261
2. Li Y., Nowotny P., Holmans P., Smemo S., Kauwe J.S., Hinrichs A.L., Tacey K., Doil L., van Luchene R., Garcia V., Rowland C., Schrodi S., Leong D., Gogic G., Chan J., Cravchik A., Ross D., Lau K., Kwok S., Chang S.Y., Catanese J., Sninsky J., White T.J., Hardy J., Powell J., Lovestone S., Morris J.C., Thal L., Owen M., Williams J., Goate A., and Grupe A. Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proc. Natl. Acad. Sci. USA 101 44 (2004) 15688-15693
3. Lu K.P. Pinning down cell signaling, cancer and Alzheimer's disease. Trends Biochem. Sci. 29 4 (2004) 200-209
4. Lu P.J., Wulf G., Zhou X.Z., Davies P., and Lu K.P. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein. Nature 399 6738 (1999) 784-788
5. Morris J.C., Ernesto C., Schafer K., Coats M., Leon S., Sano M., Thal L.J., and Woodbury P. Clinical dementia rating training and reliability in multicenter studies: the Alzheimer's Disease Cooperative Study experience. Neurology 48 6 (1997) 1508-1510
6. Myers A., Wavrant De-Vrieze F., Holmans P., Hamshere M., Crook R., Compton D., Marshall H., Meyer D., Shears S., Booth J., Ramic D., Knowles H., Morris J.C., Williams N., Norton N., Abraham R., Kehoe P., Williams H., Rudrasingham V., Rice F., Giles P., Tunstall N., Jones L., Lovestone S., Williams J., Owen M.J., Hardy J., and Goate A. Full genome screen for Alzheimer disease: stage II analysis. Am. J. Med. Genet. 114 2 (2002) 235-244
7. Pastorino L., Sun A., Lu P.J., Zhou X.Z., Balastik M., Finn G., Wulf G., Lim J., Li S.H., Li X., Xia W., Nicholson L.K., and Lu K.P. The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. Nature 440 7083 (2006) 528-534
8. Poli M., Gatta L.B., Dominici R., Lovati C., Mariani C., Albertini A., and Finazzi D. DNA sequence variations in the prolyl isomerase Pin1 gene and Alzheimer's disease. Neurosci. Lett. 389 2 (2005) 66-70
9. Segat L., Pontillo A., Annoni G., Trabattoni D., Vergani C., Clerici M., Arosio B., and Crovella S. PIN1 promoter polymorphisms are associated with Alzheimer's disease. Neurobiol. Aging (2005)
10. Wijsman E.M., Daw E.W., Yu C.E., Payami H., Steinbart E.J., Nochlin D., Conlon E.M., Bird T.D., and Schellenberg G.D. Evidence for a novel late-onset Alzheimer disease locus on chromosome 19p13.2. Am. J. Hum. Genet. 75 3 (2004) 398-409