Control of daughter cell fates during asymmetric division: Interaction of Numb and Notch

Neuron

Volumn 17, Issue 1, 1996, Pages 27-41

  Guo, Ming ^a   Jan, Lily Yeh ^a   Jan, Yuh Nung ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HYBRID PROTEIN; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; RECEPTOR PROTEIN;

ANIMAL TISSUE; ARTICLE; CELL COMMUNICATION; CELL DIVISION; CELL INTERACTION; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SENSE ORGAN; STEM CELL;

EID: 0030199973     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80278-0     Document Type: Article

References (79)

1. Artavanis-Tsakonas, S., and Simpson, P. (1991). Choosing a cell fate: a view from the Notch locus. Trends Genet. 7, 403-408.
2. Artavanis-Tsakonas, S., Matsuno, K., and Fortini, M.E. (1995). Notch signaling. Science 268, 225-232.
3. Ashburner, M. (1982). The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase III: hypomorphic mutations affecting the expression of Hairless. Genetics 101, 447-459.
4. Ashburner, M. (1989). Drosophila: A Laboratory Handbook (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
5. Axelrod, J.D., Matsuno, K., Artavanis-Tsakonas, S., and Perrimon, N. (1996). Interaction between wingless and Notch signaling pathways mediated by Dishevelled. Science 277, 1826-1832.
6. Bailey, A., and Posakony, J. (1995). Suppressor of Hairless directly activates transcription of Enhancer of split complex genes in response to Notch receptor activity. Genes Dev. 9, 2609-2622.
7. Bang, A., Bailey, A., and Posakony, J. (1995). Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulates the activity of the Notch signaling pathway. Dev. Biol. 172, 479-494.
8. Bartel, P., Chien, C.T., Sternglanz, R., and Fields, S. (1993). Using the two-hybrid system to detect protein-protein interactions. In Cellular Interactions in Development: A Practical Approach, D.A. Hartley, ed. (Oxford: Oxford University Press), pp. 153-179.
9. Bate, C.M. (1978). Development of sensory systems in arthropods. In Handbook of Sensory Physiology, M. Jacobson, ed. (New York: Springer-Verlag), pp. 1-53.
10. Bier, E., Ackerman, L., Barbel, S., Jan, L.Y., and Jan, Y.N. (1988). Identification and characterization of a neuron-specific nuclear antigen in Drosophila. Science 240, 913-916.
11. Bierkamp, C., and Campos-Ortega, J.A. (1993). A zebrafish homologue of the Drosophila neurogenic gene Notch and its pattern of transcription during early embryogenesis. Mech. Dev. 43, 87-100.
12. Blochlinger, K., Bodmer, R., Jan, L.Y., and Jan, Y.N. (1990). Patterns of expression of Cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos. Genes Dev. 4, 1322-1331.
13. Bodmer, R., and Jan, Y.N. (1987). Morphological differentiation of the embryonic peripheral neurons in Drosophila. Roux's Arch. Dev. Biol. 196, 69-77.
14. Bodmer, R., Carretto, R., and Jan, Y.N. (1989). Neurogenesis of the peripheral nervous system in Drosophila melanogaster embryos: DMA replication patterns and cell lineages. Neuron 3, 21-32.
15. Bork, P., and Margolis, B. (1995). A phosphotyrosine interaction domain. Cell 80, 693-694.
16. Brand, A.H., and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
17. Brand, M., Jarman, A.P., Jan, L.Y., and Jan, Y.N. (1993). asense is a Drosophila neural precursor gene and is capable of initiating sense organ formation. Development 119, 1-17.
18. Brewster, R., and Bodmer, R. (1995). Origin and specification of type II sensory neurons in Drosophila. Development 121, 2923-2936.
19. Brown, J.L., Sonoda, S., Ueda, H., Scott, M., and Wu, C. (1991). Repression of the Drosophila fushi tarazu (ftz) segmentation gene. EMBO J. 10, 665-674.
20. Cagan, R.L., and Ready, D.F. (1989). Notch is required for successive cell decisions in the developing Drosophila retina. Genes Dev. 3, 1099-1112.
21. Campos-Ortega, J.A. (1988). Cellular interactions during early neurogenesis in Drosophila melanogaster. Trends Neurosci. 11, 400-405.
22. Campos-Ortega, J.A., and Hartenstein, V. (1985). The Embryonic Development of Drosophila melanogaster (New York: Springer-Verlag).
23. Campuzano, S., and Modolell, J. (1992). Patterning of the Drosophila nervous system: the achaete-scute gene complex. Trends Genet. 8, 202-208.
24. Corbin, V., Michelson, A.M., Abmayr, S.M., Neel, V., Alcamo, E., Maniatis, T., and Young, M.W. (1991). A role for the Drosophila neurogenic genes in mesoderm differentiation. Cell 67, 311-323.
25. Delidakis, C., and Artavanis-Tsakonas, S. (1992). The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proc. Natl. Acad. Sci. USA 89, 8731-8735.
26. Diederich, R.J., Matsuno, K., Hing, H., and Artavanis-Tsakonas, S. (1994). Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. Development 120, 473-481.
27. Doherty, D., Feger, G., Younger-Shepherd, S., Jan, L.Y., and Jan, Y.N. (1996). Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10, 421-434.
28. Fortini, M.E., and Artavanis-Tsakonas, S. (1994). The Suppressor of Hairless protein participates in Notch receptor signaling. Cell 79, 273-282.
29. Fortini, M.E., Rebay, I., Caron, L.A., and Artavanis-Tsakonas, S. (1993). An activated Notch receptor blocks cell fate commitment in the developing Drosophila eye. Nature 365, 555-557.
30. Ghysen, A., and Dambly-Chaudiere, C. (1988). From DNA to form: the achaete-scute complex. Genes Dev. 7, 723-733.
31. Ghysen, A., Dambly-Chaudiere, C., Aceves, E., Jan, L.Y., and Jan, Y.N. (1986). Sensory neurons and peripheral pathways in Drosophila embryos. Roux's Arch. Dev. Biol. 795, 281-289.
32. Ghysen, A., Dambly-Chaudiere, C., Jan, L.Y., and Jan, Y.N. (1993). Cell interactions and gene interactions in peripheral neurogenesis. Genes Dev. 7, 723-733.
33. Giniger, E., Jan, L.Y., and Jan, Y.N. (1993). Specifying the path of the intersegmental nerve of the Drosophila embryo: a role for Delta and Notch. Development 117, 431-440.
34. Guo, M., Bier, E., Jan, L.Y., and Jan, Y.N. (1995). tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS. Neuron 14, 913-925.
35. Harrison, S., and Travers, A. (1990). The tramtrack gene encodes a Drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression pattern. EMBO J. 9, 207-216.
36. Hartenstein, V., and Posakony, J.W. (1989). Development of adult sensilla on the wing and notum of Drosophila melanogaster. Development 107, 389-405.
37. Hartenstein, V., and Posakony, J.W. (1990). A dual function of the Notch gene in Drosophila sensillum development. Dev. Biol. 142, 13-30.
38. Heitzler, P., and Simpson, P. (1991). The choice of cell fate in the epidermis of Drosophila. Cell 64, 1083-1092.
39. Horvitz, H.R., and Herskowitz, I. (1992). Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question. Cell 68, 237-255.
40. Hsieh, J.J.-D., Henkel, T., Salmon, P., Robey, E., Peterson, M.G., and Hayward, S.D. (1996). Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16, 952-959.
41. Jan, Y.N., and Jan L. Y. (1995). Maggot's hair and bug's eye: role of cell interactions and intrinsic factors in cell fate specification. Neuron 14, 1-5.
42. Kavanaugh, W.M., and Williams, L.T. (1994). An alternative to SH2 domains for binding tyrosine-phosphorylated proteins. Science 266, 1862-1865.
43. Kavanaugh, W.M., Turck, C.W., and Williams, L.T. (1995). PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine. Science 268 , 1177-1179.
44. Kidd, S., Kelley, M.R., and Young, M.W. (1986). Sequence of the Notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors. Mol. Cell. Biol. 6, 3094-3108.
45. Knoblich, J., Jan, L.Y., and Jan, Y.N. (1995). Localization of Numb and Prospero via a novel mechanism for asymmetric protein segregation. Nature 377, 624-627.
46. Knust, E., Schrons, H., Grawe, F., and Campos-Ortega, J.A. (1992). Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics 132, 505-518.
47. Kopczynski, C.C., Alton, A.K., Fechtel, K., Kooh, P.J., and Muskavitch, M.A.T. (1988). Delta, a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factor of vertebrates. Genes Dev. 2, 1723-1735.
48. Laminet, A.A., Apell, G., Conroy, L., and Kavanaugh, W.M. (1996). Affinity, specificity, and kinetics of the interaction of the SHC phosphotyrosine binding domain with asparagine-X-X-phosphotyrosine motifs of growth factor receptors. J. Biol. Chem. 271, 264-269.
49. Lecourtois, M., and Schweiguth, F. (1995). The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split complex genes triggered by Notch signaling. Genes Dev. 9, 2598-2608.
50. Lehmann, R., Jimenez, F., Dietrich, U., and Campos-Ortega, J.A. (1983). On the phenotype and development of mutants of early neurogenesis in Drosophila melanogaster. Roux's Arch. Dev. Biol. 192, 62-74.
51. Lieber, T., Kidd, S., Alcamo, E., Corbin, V., and Young, M.W. (1993). Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7, 1949-1965.
52. Luo, L., Liao, Y.J., Jan, L.Y., and Jan, Y.N. (1994). Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes Dev. 8, 1787-1802.
53. Lyman, D. and Yedvobnick, B. (1995). Drosophila Notch receptor activity suppresses Hairless function during adult external sensory organ development. Genetics 141, 1491-1505.
54. Matsuno, K., Diederich, R.J., Go, M.J., Blaumueller, C.M., and Artavanis-Tsakonas, S. (1995). Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development 121, 2633-2644.
55. Parks, A., and Muskavitch, M.A.T. (1993). Delta function is required for bristle organ determination and morphogenesis in Drosophila. Dev. Biol. 157, 484-496.
56. Posakony, J.W. (1994). Nature versus nurture: asymmetric cell divisions in Drosophila bristle development. Cell 76, 415-418.
57. Read, D., and Manley, J. (1992). Alternatively spliced transcripts of the Drosophila tramtrack gene encode zinc finger proteins with distinct DMA binding specificities. EMBO J. 11, 1035-1044.
58. Read, D., Levine, M., and Manley, J. (1992). Ectopic expression of the Drosophila tramtrack gene results in multiple embryonic defects, including repression of even-skipped and fushi tarazu. Mech. Dev. 38, 183-196.
59. Rebay, I., Fleming, R.J., Fehon, R.G., Cherbas, L., Cherbas, P., and Artavanis-Tsakonas, S. (1991). Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 67, 687-699.
60. Rebay, I., Fehon, R.G., and Artavanis-Tsakonas, S. (1993). Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell 74, 319-329.
61. Rhyu, M. (1994). How sister cells acquire different fates: the role of numb in asymmetric divisions. PhD thesis, University of California, San Francisco, California.
62. Rhyu, M., Jan, L., and Jan, Y.N. (1994). Asymmetric distribution of numb protein during division of the sensory organ precursor confers distinct fates to daughter cells. Cell 76, 477-491.
63. Ruohola, H., Bremer, K.A., Baker, D., Swedlow, J.R., Jan, L.Y., and Jan, Y.N. (1991). Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila. Cell 66, 433-449.
64. Schweisguth, F., and Posakony, J.W. (1994). Antagonistic activities of Suppressor-of-Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis. Development 120, 1433-1441.
65. Spana, E., Kopczynski, C., Goodman, C., and Doe, C. (1995). Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 121, 3187-3195.
66. Struhl, G., Fitzgerald, K., and Greenwald, I. (1993). Intrinsic activity of the lin-12 and Notch intracellular domains in vivo. Cell 74, 331-345.
67. Tamura, K., Taniguchi, Y., Minoguchi, S., Saka, T., Tun, T., Furukawa, T., and Honjo, T. (1995). Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jk/ Su(H). Curr. Biol. 5, 1416-1423.
68. Tata, F., and Hartley, D.A. (1995). Inhibition of cell fate in Drosophila by Enhancer of split genes. Mech. Dev. 51, 305-315.
69. Uemura, T., Shepherd, S., Ackerman, L., Jan, L.Y., and Jan, Y.N. (1989). numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 58, 349-360.
70. Wharton, K.A., Johansen, K.M., Xu, T., and Artavanis-Tsakonas, S. (1985). Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell 43, 567-581.
71. Vaessin, H., Bremer, K., Knust, E., and Campos-Ortega, J.A. (1987). The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats. EMBO J. 6, 3431-3440.
72. Vaessin, H., Grell, E., Wolff, E., Bier, E., Jan, L.Y., and Jan., Y.N. (1991). prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell 67, 941-953.
73. van der Geer, P., and Pawson, T. (1995). The PTB domain: a new protein module implicated in signal transduction. Trends Biochem. Sci. 20, 277-280.
74. Weinmaster, G., Roberts, V.J., and Lemke, G. (1991). A homolog of Drosophila Notch expressed during mammalian development. Development 113, 199-205.
75. Weinmaster, G., Roberts, V.J., and Lemke, G. (1992). Notch2: a second mammalian Notch gene. Development 116, 931-941.
76. Xu, T., Rebay, I., Fleming, R. J., Scottgale, T.N., and Artavanis-Tsakonas, S. (1990). The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis. Genes Dev. 4, 464-475.
77. Xu, T., Caron, L.A., Fehon, R.G., and Artavanis-Tsakonas, S. (1992). The involvement of the Notch locus in Drosophila oogenesis. Development 115, 913-922.
78. Zhong, W.M., Feder, J.N., Jiang, M.M., Jan, L.Y., and Jan, Y.N. (1996). Asymmetric localization of a mammalian Numb homolog during mouse cortical neurogenesis. Neuron 17, this issue.
79. Zipursky, S.L., Venkatesh, T.R., Teplow, D.B., and Benzer, S. (1984). Neuronal development in the Drosophila retina: monoclonal antibodies as molecular probes. Cell 36, 15-26.