Cutting edge: Protective effects of Notch-1 on TCR-induced apoptosis

Journal of Immunology

Volumn 162, Issue 2, 1999, Pages 635-638

  Jehn, Birgit M ^a,b   Bielke, Wolfgang ^a,c   Pear, Warren S ^d   Osborne, Barbara A ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE;

ANIMALS; APOPTOSIS; CELL DEATH; CELL LINE; DNA-BINDING PROTEINS; HUMANS; HYBRID CELLS; LYMPHOMA, T-CELL; MEMBRANE PROTEINS; MICE; RECEPTOR, NOTCH1; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RETROVIRIDAE; SACCHAROMYCES CEREVISIAE; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0033556251     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Liu, Z. G., S. W. Smith, K. A. McLaughlin, L. M. Schwartz, and B. A. Osborne. 1994. Apoptotic signals delivered through the T cell receptor require the immediate early gene nur77. Nature 367:281.
2. Woronicz, J. D., B. Calnan, V. Ngo, and A. Winoto. 1994. Requirement for the orphan receptor Nur77 in apoptosis of T cell hybridomas. Nature 367:277.
3. Winoto, A. 1997. Cell death in the regulation of immune responses. Curr. Opin. Immunol. 9:365.
4. Artavanis-Tsakonas, S., K. Matsuno, and M. E. Fortini. 1995. Notch signaling. Science 268:225.
5. Chan, Y. M., and Y. N. Jan. 1998. Roles for proteolysis and trafficking in notch maturation and signal transduction. Cell 94:423.
6. Ellisen, L. W., J. Bird, D. C. West, A. L. Soreng, T. C. Reynolds, S. D. Smith, and J. Sklar. 1991. TAN1. the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in lymphoblastic neoplasms. Cell 66:649.
7. Jhappan, C., D. Gallahan, C. Stahle, E. Chu, G. H. Smith, G. Merlino, and R. Callahan. 1992. Expression of an activated Notch-related int3 transgene interferes with cell differentiation and induces neoplastic transformation in the mammary and the salivary glands. Genes Dev. 6:345.
8. 1 and S phase protein phosphatase that associates with Cdk2. Cell 75:791.
9. Zervos, A. S., J. Gyuris, and R. Brent. 1993. Mxil, a protein that specifically interacts with Max to bind MycMax recognition sites. Cell 72:223.
10. + encodes a protein phosphatase that dephosphorylates p34cdc2. Mol. Biol. Cell 13:73.
11. Pear, W. S., J. C. Aster, M. L. Scott, R. P. Hasserjian, B. Soffer, J. D. Sklar, and D. Baltimore. 1996. Exclusive development of T cell neoplasms in mice transplanted with bone marrow-expressing activated Notch alleles. J. Exp. Med. 83: 2283.
12. Breeden, L., and K. Nasmyth. 1987. Similarity between the cell cycle genes of the budding yeast and fission yeast and the Notch gene of Drosophila. Nature 329: 651.
13. Lux, S. E., K. M. John, and V. Bennett. 1990. Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle proteins. Nature 344:36.
14. Hasserjian, R., J. Aster, D. Davi, D. Weinberg, and J. Sklar. 1996. Modulated expression of Notch-1 during thymocyte development. Blood 88:970.
15. Harlow, E., and D. Lane. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Press, Cold Spring Harbor, NY.