Cyclopamine inhibition of Sonic hedgehog signal transduction is not mediated through effects on cholesterol transport

Developmental Biology

Volumn 224, Issue 2, 2000, Pages 440-452

  Incardona, John P ^a   Gaffield, William ^b   Lange, Yvonne ^c   Cooney, Adele ^d   Pentchev, Peter G ^d   Liu, Sharon ^e   Watson, John A ^e   Kapur, Raj P ^a   Roelink, Henk ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b WESTERN REGIONAL RESEARCH CENTER   (United States)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Holoprosencephaly; Memb rane trafficking; Neural development; Progesterone; Teratogen; U18666A

Indexed keywords

3BETA (2 DIETHYLAMINOETHOXY)ANDROST 5 EN 17 ONE; ALKALOID DERIVATIVE; CELL RECEPTOR; CYCLOPAMINE; CYCLOPAMINE 4 EN 3 ONE; CYCLOPOSINE; JERVINE; NERVE PROTEIN; NIEMANN PICK C1 PROTEIN; PROGESTERONE; PROTEIN PATCHED; SOLASODINE; SONIC HEDGEHOG PROTEIN; STEROID; TETRAHYDROJERVINE; TOMATIDINE; UNCLASSIFIED DRUG; VERATRAMINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CHICK EMBRYO; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYCLOPIA; HOLOPROSENCEPHALY; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STEROL ANALYSIS; STRUCTURE ACTIVITY RELATION; TERATOGENICITY;

ANIMALIA; CYCLOPIA; ERINACEIDAE;

EID: 0034663090     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2000.9775     Document Type: Article

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