Potential of flavonoids as anti-inflammatory agents: Modulation of pro-inflammatory gene expression and signal transduction pathways

Current Drug Metabolism

Volumn 10, Issue 3, 2009, Pages 256-271

  Tunon M J ^a   Garcia Mediavilla M V ^a   Sanchez Campos S ^a   Gonzalez Gallego J ^a  

^a UNIVERSITY OF LEÓN   (Spain)

Author keywords

Adhesion molecules; Cyclooxygenase; Flavonoids; Inflammation; Lipooxygenase; Mitogen activated protein kinases; Nitric oxide synthase; Nuclear factor kappa B

Indexed keywords

APIGENIN; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE; C REACTIVE PROTEIN; CCAAT ENHANCER BINDING PROTEIN; CHEMOKINE RECEPTOR CXCR4; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPIGALLOCATECHIN GALLATE; FLAVONOID; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; KAEMPFEROL; LEUKOTRIENE; LUTEOLIN; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; NEURONAL NITRIC OXIDE SYNTHASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROSTAGLANDIN SYNTHASE; PROSTANOID; QUERCETIN; STAT PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ALLERGIC ENCEPHALOMYELITIS; ANTIINFLAMMATORY ACTIVITY; CELL ADHESION; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG STRUCTURE; DRUG TARGETING; ENDOTHELIUM CELL; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HUMAN; INFLAMMATION; MACROPHAGE ACTIVATION; NONHUMAN; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYCLOOXYGENASE 2; CYTOKINES; FLAVONOIDS; GENE EXPRESSION REGULATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; SIGNAL TRANSDUCTION;

EID: 65549150307     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920009787846369     Document Type: Review

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