Differential modulation of cyclooxygenase-mediated prostaglandin production by the putative cancer chemopreventive flavonoids tricin, apigenin and quercetin

Cancer Chemotherapy and Pharmacology

Volumn 58, Issue 6, 2006, Pages 816-825

  Al Fayez, Mohammad ^a   Cai, Hong ^a   Tunstall, Richard ^a   Steward, William P ^a   Gescher, Andreas J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Cancer chemoprevention; Cyclooxygenase; Flavonoids; Prostaglandin E 2

Indexed keywords

APIGENIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FLAVONOID; PHORBOL ESTER; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; QUERCETIN; TRICIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER PREVENTION; CHEMOPROPHYLAXIS; COLON CANCER; COLON MUCOSA; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; IMMUNOASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; ANTICARCINOGENIC AGENTS; APIGENIN; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; HT29 CELLS; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; QUERCETIN; SHEEP; TETRADECANOYLPHORBOL ACETATE;

EID: 33748468361     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-006-0228-3     Document Type: Article

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