-
1
-
-
0030825407
-
Chemokines
-
B.J. Rollins Chemokines Blood 90 1997 909 928
-
(1997)
Blood
, vol.90
, pp. 909-928
-
-
Rollins, B.J.1
-
2
-
-
0032509889
-
Chemokines-chemotactic cytokines that mediate inflammation
-
A.D. Luster Chemokines-chemotactic cytokines that mediate inflammation New Engl. J. Med. 338 1998 436 445
-
(1998)
New Engl. J. Med.
, vol.338
, pp. 436-445
-
-
Luster, A.D.1
-
3
-
-
23844432299
-
Multi-faceted strategies to combat disease by interference with the chemokine system
-
Z. Johnson Multi-faceted strategies to combat disease by interference with the chemokine system Trends Immunol. 26 2005 268 274
-
(2005)
Trends Immunol.
, vol.26
, pp. 268-274
-
-
Johnson, Z.1
-
5
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
M.J. Leckie Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response Lancet 356 2000 2144 2148
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
-
6
-
-
4544304222
-
Defining a link with asthma in mice congenitally deficient in eosinophils
-
J.J. Lee Defining a link with asthma in mice congenitally deficient in eosinophils Science 305 2004 1773 1776
-
(2004)
Science
, vol.305
, pp. 1773-1776
-
-
Lee, J.J.1
-
7
-
-
4544274172
-
A critical role for eosinophils in allergic airways remodeling
-
A.A. Humbles A critical role for eosinophils in allergic airways remodeling Science 305 2004 1776 1779
-
(2004)
Science
, vol.305
, pp. 1776-1779
-
-
Humbles, A.A.1
-
8
-
-
0037022386
-
The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness
-
A.A. Humbles The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness Proc. Natl. Acad. Sci. U. S. A. 99 2002 1479 1484
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 1479-1484
-
-
Humbles, A.A.1
-
9
-
-
0036199934
-
CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation
-
W. Ma CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation J. Clin. Invest. 109 2002 621 628
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 621-628
-
-
Ma, W.1
-
10
-
-
0022555496
-
Identification of C5ades arg and an anionic neutrophil-activating peptide (ANAP) in psoriatic scales
-
J.M. Schroder, and E. Christophers Identification of C5ades arg and an anionic neutrophil-activating peptide (ANAP) in psoriatic scales J. Invest. Dermatol. 87 1986 53 58
-
(1986)
J. Invest. Dermatol.
, vol.87
, pp. 53-58
-
-
Schroder, J.M.1
Christophers, E.2
-
11
-
-
0034578357
-
Plasma level of IL-8 in patients with psoriasis and its correlation with psoriasis area and severity index and the clinical type of the disease
-
A. Pietrzak Plasma level of IL-8 in patients with psoriasis and its correlation with psoriasis area and severity index and the clinical type of the disease Ann. Univ. Mariae Curie Sklodowska [Med] 55 2000 261 267
-
(2000)
Ann. Univ. Mariae Curie Sklodowska [Med]
, vol.55
, pp. 261-267
-
-
Pietrzak, A.1
-
12
-
-
0032822643
-
Fully human anti-interleukin-8 monoclonal antibodies: Potential therapeutics for the treatment of inflammatory disease states
-
X.D. Yang Fully human anti-interleukin-8 monoclonal antibodies: potential therapeutics for the treatment of inflammatory disease states J. Leukoc. Biol. 66 1999 401 410
-
(1999)
J. Leukoc. Biol.
, vol.66
, pp. 401-410
-
-
Yang, X.D.1
-
13
-
-
0042525815
-
Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB
-
B.M. Mian Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB Clin. Cancer Res. 9 2003 3167 3175
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 3167-3175
-
-
Mian, B.M.1
-
14
-
-
0036310021
-
Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma
-
S. Huang Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma Am. J. Pathol. 161 2002 125 134
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 125-134
-
-
Huang, S.1
-
15
-
-
4544275759
-
Efficacy and safety of a monoclonal antibody recognizing interleukin-8 in COPD: A pilot study
-
D.A. Mahler Efficacy and safety of a monoclonal antibody recognizing interleukin-8 in COPD: a pilot study Chest 126 2004 926 934
-
(2004)
Chest
, vol.126
, pp. 926-934
-
-
Mahler, D.A.1
-
16
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
E.A. Berger Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease Annu. Rev. Immunol. 17 1999 657 700
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
-
17
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
M. Samson Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene Nature 382 1996 722 725
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
-
18
-
-
0032550337
-
Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity
-
M. Mack Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity J. Exp. Med. 187 1998 1215 1224
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1215-1224
-
-
MacK, M.1
-
19
-
-
5644247983
-
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
-
M.M. Lederman Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5 Science 306 2004 485 487
-
(2004)
Science
, vol.306
, pp. 485-487
-
-
Lederman, M.M.1
-
20
-
-
0033559346
-
Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients
-
T.L. Sorensen Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients J. Clin. Invest. 103 1999 807 815
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 807-815
-
-
Sorensen, T.L.1
-
21
-
-
0035157253
-
CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis
-
C. Trebst CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis Am. J. Pathol. 159 2001 1701 1710
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 1701-1710
-
-
Trebst, C.1
-
22
-
-
0033536062
-
CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1 alpha and IP-10 are expressed in demyelinating brain lesions
-
K.E. Balashov CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1 alpha and IP-10 are expressed in demyelinating brain lesions Proc. Natl. Acad. Sci. U. S. A. 96 1999 6873 6878
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 6873-6878
-
-
Balashov, K.E.1
-
23
-
-
0032572719
-
Decreased lesion formation in CCR2(-/-) Mice reveals a role for chemokines in the initiation of atherosclerosis
-
L. Boring Decreased lesion formation in CCR2(-/-) Mice reveals a role for chemokines in the initiation of atherosclerosis Nature 394 1998 894 897
-
(1998)
Nature
, vol.394
, pp. 894-897
-
-
Boring, L.1
-
24
-
-
0034596949
-
Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
-
L. Izikson Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2 J. Exp. Med. 192 2000 1075 1080
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1075-1080
-
-
Izikson, L.1
-
25
-
-
0035312350
-
Magic bullets for protein kinases
-
A.C. Bishop Magic bullets for protein kinases Trends Cell Biol. 11 2001 167 172
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 167-172
-
-
Bishop, A.C.1
-
26
-
-
16244416531
-
Identification of nonpeptidic small-molecule inhibitors of interleukin-2
-
N.D. Waal Identification of nonpeptidic small-molecule inhibitors of interleukin-2 Bioorg. Med. Chem. Lett. 15 2005 983 987
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 983-987
-
-
Waal, N.D.1
-
27
-
-
0034625144
-
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
-
T. Dragic A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5 Proc. Natl. Acad. Sci. U. S. A. 97 2000 5639 5644
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5639-5644
-
-
Dragic, T.1
-
28
-
-
0030022954
-
Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist
-
A.E.I. Proudfoot Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist J. Biol. Chem. 271 1996 2599 2603
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2599-2603
-
-
Proudfoot, A.E.I.1
-
29
-
-
0028013658
-
Two-site binding of C5a by its receptor: An alternative binding paradigm for G protein-coupled receptors
-
S.J. Siciliano Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors Proc. Natl. Acad. Sci. U. S. A. 91 1994 1214 1218
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 1214-1218
-
-
Siciliano, S.J.1
-
30
-
-
0029131699
-
A dominant negative inhibitor indicates that monocyte chemoattractant protein 1 functions as a dimer
-
Y. Zhang, and B.J. Rollins A dominant negative inhibitor indicates that monocyte chemoattractant protein 1 functions as a dimer Mol. Cell. Biol. 15 1995 4851 4855
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4851-4855
-
-
Zhang, Y.1
Rollins, B.J.2
-
31
-
-
0028952523
-
Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues
-
J.H. Gong, and I. Clark-Lewis Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues J. Exp. Med. 181 1995 631 640
-
(1995)
J. Exp. Med.
, vol.181
, pp. 631-640
-
-
Gong, J.H.1
Clark-Lewis, I.2
-
32
-
-
0033527580
-
Amino-terminally modified RANTES analogues demonstrate differential effects on RANTES receptors
-
A.E. Proudfoot Amino-terminally modified RANTES analogues demonstrate differential effects on RANTES receptors J. Biol. Chem. 274 1999 32478 32485
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32478-32485
-
-
Proudfoot, A.E.1
-
33
-
-
0026694563
-
Endothelial cell binding of NAP-1/IL-8: Role in neutrophil emigration
-
A. Rot Endothelial cell binding of NAP-1/IL-8: role in neutrophil emigration Immunol. Today 13 1992 291 294
-
(1992)
Immunol. Today
, vol.13
, pp. 291-294
-
-
Rot, A.1
-
34
-
-
0030810177
-
Glycosaminoglycans mediate cell surface oligomerization of chemokines
-
A.J. Hoogewerf Glycosaminoglycans mediate cell surface oligomerization of chemokines Biochemistry 36 1997 13570 13578
-
(1997)
Biochemistry
, vol.36
, pp. 13570-13578
-
-
Hoogewerf, A.J.1
-
35
-
-
0037452728
-
Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines
-
A.E.I. Proudfoot Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines Proc. Natl. Acad. Sci. U. S. A. 100 2003 1885 1890
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 1885-1890
-
-
Proudfoot, A.E.I.1
-
36
-
-
7944221827
-
The X-ray structure of RANTES: Heparin-derived disaccharides allows the rational design of chemokine inhibitors
-
J.P. Shaw The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors Structure (Camb) 12 2004 2081 2093
-
(2004)
Structure (Camb)
, vol.12
, pp. 2081-2093
-
-
Shaw, J.P.1
-
37
-
-
0035815694
-
The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity
-
A.E. Proudfoot The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity J. Biol. Chem. 276 2001 10620 10626
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10620-10626
-
-
Proudfoot, A.E.1
-
38
-
-
6344269426
-
Interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system
-
Z. Johnson Interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system J. Immunol. 173 2004 5776 5785
-
(2004)
J. Immunol.
, vol.173
, pp. 5776-5785
-
-
Johnson, Z.1
-
39
-
-
0141757326
-
Inactivation of TNF signaling by rationally designed dominant-negative TNF variants
-
P.M. Steed Inactivation of TNF signaling by rationally designed dominant-negative TNF variants Science 301 2003 1895 1898
-
(2003)
Science
, vol.301
, pp. 1895-1898
-
-
Steed, P.M.1
-
40
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation
-
E. Hirsch Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation Science 287 2000 1049 1053
-
(2000)
Science
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
-
41
-
-
0034635221
-
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction
-
Z. Li Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant- mediated signal transduction Science 287 2000 1046 1049
-
(2000)
Science
, vol.287
, pp. 1046-1049
-
-
Li, Z.1
-
42
-
-
0034635264
-
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
-
T. Sasaki Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration Science 287 2000 1040 1046
-
(2000)
Science
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
-
43
-
-
24744435115
-
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
-
M. Camps Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis Nat. Med. 11 2005 936 943
-
(2005)
Nat. Med.
, vol.11
, pp. 936-943
-
-
Camps, M.1
-
44
-
-
0027211704
-
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation
-
D.W. Banner Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation Cell 73 1993 431 445
-
(1993)
Cell
, vol.73
, pp. 431-445
-
-
Banner, D.W.1
-
45
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
K. Palczewski Crystal structure of rhodopsin: a G protein-coupled receptor Science 289 2000 739 745
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
-
46
-
-
0033634827
-
Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine
-
E.H. Walker Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine Mol. Cell 6 2000 909 919
-
(2000)
Mol. Cell
, vol.6
, pp. 909-919
-
-
Walker, E.H.1
|