Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-κB inactivation in RAW 264.7 macrophage cells

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 12, 2007, Pages 2345-2351

  Kim, Jong Bin ^a   Han, Ah Reum ^b   Park, Eun Young ^a   Kim, Ji Yeon ^a   Cho, Woong ^a   Lee, Jun ^b   Seo, Eun Kyoung ^b   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

^b Ewha Womans University   (South Korea)

Author keywords

Anti inflammation; Cyclooxygenase 2; Inducible nitric oxide synthase; Nuclear factor B; Poncirin; Poncirus trifoliata

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; CYTOKINE; FLAVONOID GLYCOSIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PONCIRIN; PROTEIN P50; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME REGULATION; IN VITRO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PHARMACODYNAMICS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TRIFOLIATE ORANGE;

BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLAVONOIDS; HUMANS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PONCIRUS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 36849072564     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.2345     Document Type: Article

References (39)

1. Brown K. L., Cosseau C., Gardy J. L., Hancock R. E., Trends Immunol., 28, 260-266 (2007).
2. Posadas I., Terencio M. C., Guillén I., Ferrándiz M. L., Coloma J., Payá M., Alcaraz M. J., Naunyn-Schmiedebergs Arch. Pharmacol., 361, 98-106 (2000).
3. Moncada S., Palmer R. M., Higgs E. A., Pharmacol. Rev., 43, 109-142 (1991).
4. Yun H. Y., Dawson T. T., Dawson T. M., Crit. Rev. Neurobiol., 10, 291-316 (1996).
5. Stokes K. Y., Cooper D., Tailor A., Granger D. N., Free Radic. Biol. Med., 8, 1026-1036 (2002).
6. Vane J. R., Botting R. M., Am. J. Med., 104, S2-S8 (1998).
7. Vane J. R., Bakhle Y. S., Botting R. M., Annu. Rev. Pharmacol. Toxicol., 38, 97-120 (1998).
8. Needleman P., Isakson P. C., J. Rheumatol., 49, 6-8 (1997).
9. Seybold V. S., Jia Y. P., Abrahams L.G., Pain, 105, 47-55 (2003).
10. Bishop-Bailey D., Calatayud S., Warner T. D., Hla T., Mitchell J. A., J. Environ. Pathol. Toxicol. Oncol., 21, 93-101 (2002).
11. Ishihara S., Rumi M. A., Okuyama T., Kinoshita Y., Curr. Med. Chem. Anti-Cancer Agents, 4, 379-387 (2004).
12. Chen F., Castranova V., Shi X., Demers L. M., Clin. Chem., 45, 7-17 (1999).
13. Baldwin A. S., Jr., Annu. Rev. Immunol., 14, 649-683 (1996).
14. Baeuerle P. A., Baltimore D., Cell, 87, 13-20 (1996).
15. Han A. R., Kim J. B., Lee J., Nam J. W., Lee I. S., Shim C. K., Lee K. T., Seo E. K., Chem. Pharm. Bull., 55, 1270-1273 (2007).
16. Mohamed T. K., Asian J. Chem., 16, 1753-1764 (2004).
17. Slade D., Ferreira D., Marais J. P. J., Phytochemistry, 66, 2177-2215 (2005).
18. Kim C. M., Sin M. K., Ahn D. K., Lee K. S., "Dictionary of Chinese Materia Mediaca," Jungdam Publishing, Soeul, 1997.
19. Park S. H., Park E. K., Kim D. H., Planta Med., 71, 24-27 (2005).
20. Liu J. C., Chan P., Hsu F. L., Chen Y. J., Hsieh M. H., Lo M. Y., Lin J. Y., Am. J. Chinese Med., 30, 629-636 (2002).
21. Teng C. M., Li H. L., Wu T. S., Huang S. C., Huang T. F., Thromb. Res., 66, 549-557 (1992).
22. Guiotto A., Rodighiero P., Quintily U., Pastorini G., Phytochemistry, 15, 348 (1976).
23. Kim H. M., Kim H. J., Park S. T., J. Ethnopharmacol., 66, 283-288 (1999).
24. Kim D. H., Bae E. A., Han M. J., Biol. Pharm. Bull., 22, 422-424 (1999).
25. Shin T. Y., Oh J. M., Choi B. J., Park W. H., Kim C. H., Jun C. D., Kim S. H., Toxicol. In Vitro, 20, 1071-1076 (2006).
26. Won J. H., Kim Y. H., Yun K. J., Park H. J., Choi J. W., Lee K. T., Br. J. Pharmacol., 148, 216-225 (2006).
27. Vandenberghe W., Plaisance S., Boone E., Debosscher K., Schmitz M. L., Fiers W., Haegeman G., J. Biol. Chem., 273, 3285-3290 (1998).
28. Chun Y. T., Sankawa U., Shoyakugaku Zasshi, 43, 314-323 (1989).
29. Lee Y. M., Kim C. Y., Kim Y. C., Kim H. M., Am. J. Chin. Med., 25, 51-56 (1997).
30. Lee Y. M., Kim D. K., Kim S. H., Shin T. Y., Kim H. M., J. Ethnopharmacol., 54, 77-84 (1996).
31. Szabo C., Ann. N.Y. Acad. Sci., 851, 422-425 (1998).
32. Martel-Pelletier J., Pelletier J. P., Fahmi H., Semin. Arthritis Rheum., 33, 155-167 (2003).
33. Feldmann M., Brennan F. M., Chantry D., Haworth C., Turner M., Katsikis P., Londei M., Abney E., Buchan G., Barrett K., Corcoran A., Kissonerghis M., Zheng R., Grubeck-loebenstein B., Barkley D., Chu C. Q., Field M., Maini R. N., Immunol. Rev., 119, 105-123 (1991).
34. Jun C. D., Choi B. M., Kim H. M., Chung H. T., J. Immunol., 154, 6541-6547 (1995).
35. Aggarwal B. B., Natarajan K., Eur. Cytokine Netw., 7, 93-124 (1996).
36. Pan M. H., Lin-Shiau S. Y., Ho C. T., Lin J. H., Lin J. K., Biochem. Pharmacol., 59, 357-367 (2000).
37. Yang F., Oz H. S., Barve S., de Villiers W. J., McClain C. J., Varilek G. W., Mol. Pharmacol., 60, 528-533 (2001).
38. Caivano M., FEBS Lett., 429, 249-253 (1998).
39. Meyer C. F., Wang X., Chang C., Templeton D., Tan T. H., J. Biol. Chem., 271, 8971-8976 (1996).