Effects of FK506 and rapamycin on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes

Biochemical Pharmacology

Volumn 66, Issue 3, 2003, Pages 439-445

  Tuñón, María Jesús ^a   Sánchez Campos, Sonia ^a   Gutiérrez, Belén ^a   Culebras, Jesús M ^b   González Gallego, Javier ^a  

^a UNIVERSITY OF LEÓN   (Spain)

^b Hospital of Leon   (Spain)

Author keywords

FK506; LPS; Nitric oxide; Nuclear factor B; Rapamycin; Rat cultured hepatocytes

Indexed keywords

DICHLORODIHYDROFLUORESCEIN DIACETATE; FLUORESCEIN DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; TACROLIMUS; UNCLASSIFIED DRUG;

ACUTE GRAFT REJECTION; ANALYTIC METHOD; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVATION; EXPERIMENT; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; INHIBITION KINETICS; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STIMULATION; WESTERN BLOTTING;

EID: 0041695625     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00288-0     Document Type: Article

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