The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells

European Journal of Pharmacology

Volumn 557, Issue 2-3, 2007, Pages 221-229

  García Mediavilla, Victoria ^a   Crespo, Irene ^a   Collado, Pilar S ^a   Esteller, Alejandro ^b   Sánchez Campos, Sonia ^a   Tuñón, María J ^a   González Gallego, Javier ^a  

^a UNIVERSITY OF LEÓN   (Spain)

^b UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

C reactive protein; Inflammation; Kaempferol; Liver; Nitric oxide; Nuclear factor kappa B; Quercetin

Indexed keywords

C REACTIVE PROTEIN; CYCLOOXYGENASE 2; CYTOKINE; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; KAEMPFEROL; MESSENGER RNA; QUERCETIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LINE; DOWN REGULATION; DRUG ACTIVATION; DRUG INHIBITION; ENZYME BLOOD LEVEL; ENZYME INHIBITION; GENE; HUMAN; HUMAN CELL; LIVER CELL; MODULATION; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; UPREGULATION;

C-REACTIVE PROTEIN; CELL LINE; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FLAVONOLS; HEPATOCYTES; HUMANS; KAEMPFEROLS; MOLECULAR STRUCTURE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; QUERCETIN;

EID: 33846582444     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.11.014     Document Type: Article

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