Stem cell engineering for the treatment of severe hemoglobinopathies

Current Molecular Medicine

Volumn 8, Issue 7, 2008, Pages 690-697

  Sadelain, Michel ^a   Boulad, Farid ^a   Lisowki, Leszek ^a   Moi, Paolo ^a   Riviere, Isabelle ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; BETA GLOBIN; BUSULFAN; GAMMA GLOBIN; HEMOGLOBIN; LENTIVIRUS VECTOR; MELPHALAN; RETROVIRUS VECTOR; RIBOZYME; GLOBIN;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ALLOGENIC BONE MARROW TRANSPLANTATION; ALPHA THALASSEMIA; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BETA THALASSEMIA; BIOENGINEERING; CANCER RISK; CELL DIFFERENTIATION; CELL MATURATION; CELL NUCLEUS TRANSPLANTATION; CLINICAL TRIAL; DISEASE FREE SURVIVAL; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; DRUG SYNTHESIS; EMBRYONIC STEM CELL; ENGRAFTMENT; ERYTHROPOIESIS; GAMMA RADIATION; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; GENETIC RECOMBINATION; GENOMIC INSTABILITY; GRAFT VERSUS HOST REACTION; HEMOGLOBIN SYNTHESIS; HEMOGLOBINOPATHY; HLA MATCHING; HUMAN; IMMUNE DEFICIENCY; IN VIVO STUDY; LEUKEMIA; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PLURIPOTENT STEM CELL; RETROPOSON; REVIEW; RNA INTERFERENCE; RNA SPLICING; SICKLE CELL ANEMIA; SOMATIC CELL; STEM CELL GENE THERAPY; SURVIVAL TIME; TRANSCRIPTION REGULATION; TRANSGENE; TRANSPOSON; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; VIRUS REPLICATION; CYTOLOGY; GENE THERAPY; GENETICS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; METHODOLOGY; TISSUE ENGINEERING;

MUS;

GENE THERAPY; GLOBINS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HEMOGLOBINOPATHIES; HUMANS; TISSUE ENGINEERING;

EID: 59249088795     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652408786241357     Document Type: Review

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