Globin gene transfer: A paradigm for transgene regulation and vector safety

Gene Therapy and Regulation

Volumn 2, Issue 2, 2004, Pages 149-175

  Rivella, Stefano ^a,b   Lisowski, Leszek ^a   Sadelain, Michel ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Hemoglobinopathies; Insertional mutagenesis; Lentiviral vectors; Mouse models; Sickle cell disease; Stem cell gene therapy; Thalassemia

Indexed keywords

GLOBIN; HEMOGLOBIN; LENTIVIRUS VECTOR;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; BETA THALASSEMIA; CELL DIFFERENTIATION; CELL LINEAGE; ERYTHROID CELL; GENE EXPRESSION; GENE INSERTION; GENE TRANSFER; HEMOGLOBIN SYNTHESIS; HEMOGLOBINOPATHY; HUMAN; MOUSE; MUTAGENESIS; NONHUMAN; ONCOGENE; REVIEW; SAFETY; SICKLE CELL ANEMIA; STEM CELL GENE THERAPY; TRANSCRIPTION REGULATION; TRANSGENE;

ANIMALIA; INSERTION SEQUENCES; LENTIVIRUS;

EID: 1342302771     PISSN: 13889532     EISSN: None     Source Type: Journal    
DOI: 10.1163/156855803322664637     Document Type: Review

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