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Volumn 9, Issue 2, 1999, Pages 152-157

Activation by locus control regions?

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN;

EID: 0032928813     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(99)80023-9     Document Type: Article
Times cited : (131)

References (45)
  • 1
    • 0023663887 scopus 로고
    • Positionindependent, high-level expression of the human β-globin gene in transgenic mice
    • Grosveld F Blom van Assendelft G Greaves DR Kollias G Positionindependent, high-level expression of the human β-globin gene in transgenic mice Cell 51 1987 975 985
    • (1987) Cell , vol.51 , pp. 975-985
    • Grosveld, F1    Blom van Assendelft, G2    Greaves, DR3    Kollias, G4
  • 2
    • 0021014396 scopus 로고
    • Beta-globin gene inactivation by DNA translocation in γβ-thalassemia
    • Kioussis D Vanin E deLange T Flavell RA Grosveld FG Beta-globin gene inactivation by DNA translocation in γβ-thalassemia Nature 306 1983 662 666
    • (1983) Nature , vol.306 , pp. 662-666
    • Kioussis, D1    Vanin, E2    deLange, T3    Flavell, RA4    Grosveld, FG5
  • 3
    • 0012953756 scopus 로고
    • γδβ thalassemia due to a de novo mutation deleting the 5′ β-globin gene activation region hypersensitive sites
    • Driscoll M Dobkin C Alter B γδβ thalassemia due to a de novo mutation deleting the 5′ β-globin gene activation region hypersensitive sites Proc Natl Acad Sci USA 86 1989 7470 7474
    • (1989) , pp. 7470-7474
    • Driscoll, M1    Dobkin, C2    Alter, B3
  • 4
    • 0022351149 scopus 로고
    • A distant gene deletion affects β-globin function in an atypical γδβ thalassemia
    • Curtin P Piratsu M Kan Y Gobert-Jones J Stephens A Lehmann H A distant gene deletion affects β-globin function in an atypical γδβ thalassemia J Clin Invest 76 1985 1554 1558
    • (1985) J Clin Invest , vol.76 , pp. 1554-1558
    • Curtin, P1    Piratsu, M2    Kan, Y3    Gobert-Jones, J4    Stephens, A5    Lehmann, H6
  • 5
    • 85119794677 scopus 로고    scopus 로고
    • Hemoglobin switching
    • in press Grosveld F Stamatoyannopoulos G Hemoglobin switching The Molecular Basis of Blood Diseases 1999 WB Saunders Company Philadelphia
    • (1999)
    • Grosveld, F1    Stamatoyannopoulos, G2
  • 6
    • 0344272073 scopus 로고
    • The β-like globin domain in human erythroid cells
    • Tuan D Solomon W Li Q London I The β-like globin domain in human erythroid cells Proc Natl Acad Sci USA 82 1985 6384 6388
    • (1985) , pp. 6384-6388
    • Tuan, D1    Solomon, W2    Li, Q3    London, I4
  • 7
    • 0022450433 scopus 로고
    • A developmentally stable chromatin structure in the human β-globin cluster
    • Forrester W Thompson C Elder J Groudine M A developmentally stable chromatin structure in the human β-globin cluster Proc Natl Acad Sci USA 83 1986 1359 1363
    • (1986) , pp. 1359-1363
    • Forrester, W1    Thompson, C2    Elder, J3    Groudine, M4
  • 8
    • 0024558096 scopus 로고
    • Human CD2 3′-flanking sequences confer high-level, T cell-specific, positionindependent gene expression in transgenic mice
    • Greaves DR Wilson FD Lang G Kioussis D Human CD2 3′-flanking sequences confer high-level, T cell-specific, positionindependent gene expression in transgenic mice Cell 56 1989 979 986
    • (1989) Cell , vol.56 , pp. 979-986
    • Greaves, DR1    Wilson, FD2    Lang, G3    Kioussis, D4
  • 9
    • 0030726908 scopus 로고    scopus 로고
    • Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals
    • Kioussis D Festenstein R Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals Curr Opin Genet Dev 7 1997 614 619
    • (1997) Curr Opin Genet Dev , vol.7 , pp. 614-619
    • Kioussis, D1    Festenstein, R2
  • 12
    • 0025107556 scopus 로고
    • A deletion of the human betaglobin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus
    • Forrester WC Epner E Driscoll MC Enver T Brice M Papayannopoulou T Groudine M A deletion of the human betaglobin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus Genes Dev 4 1990 1637 1649
    • (1990) Genes Dev , vol.4 , pp. 1637-1649
    • Forrester, WC1    Epner, E2    Driscoll, MC3    Enver, T4    Brice, M5    Papayannopoulou, T6    Groudine, M7
  • 13
    • 0021755204 scopus 로고
    • DNA sequences required for regulated expression of β-globin genes in murine erythroleukemia cells
    • Wright S de Boer E Rosenthal A Flavell R Grosveld F DNA sequences required for regulated expression of β-globin genes in murine erythroleukemia cells Phil Trans Royal Soc Lond (B) 307 1984 271 282
    • (1984) Phil Trans Royal Soc Lond (B) , vol.307 , pp. 271-282
    • Wright, S1    de Boer, E2    Rosenthal, A3    Flavell, R4    Grosveld, F5
  • 14
    • 0022549802 scopus 로고
    • Regulated expression of human A gamma-, beta-, and hybrid gamma beta-globin genes in transgenic mice: manipulation of the developmental expression patterns
    • Kollias G Wrighton N Hurst J Grosveld F Regulated expression of human A gamma-, beta-, and hybrid gamma beta-globin genes in transgenic mice: manipulation of the developmental expression patterns Cell 46 1986 89 94
    • (1986) Cell , vol.46 , pp. 89-94
    • Kollias, G1    Wrighton, N2    Hurst, J3    Grosveld, F4
  • 15
    • 0023442125 scopus 로고
    • A 3′ enhancer contributes to the stage specific expression of the human β-globin gene
    • Trudel M Costantini F A 3′ enhancer contributes to the stage specific expression of the human β-globin gene Genes Dev 1 1987 954 961
    • (1987) Genes Dev , vol.1 , pp. 954-961
    • Trudel, M1    Costantini, F2
  • 16
    • 0023547189 scopus 로고
    • Two 3′ sequences direct adult erythroid specific expression of human β-globin genes in mice
    • Behringer R Hammer R Brinster R Palmiter R Townes T Two 3′ sequences direct adult erythroid specific expression of human β-globin genes in mice Proc Natl Acad Sci USA 84 1987 7056 7060
    • (1987) , pp. 7056-7060
    • Behringer, R1    Hammer, R2    Brinster, R3    Palmiter, R4    Townes, T5
  • 17
    • 0022100680 scopus 로고
    • Erythroid-specific expression of human beta-globin genes in transgenic mice
    • Townes TM Lingrel JB Chen HY Brinster RL Palmiter RD Erythroid-specific expression of human beta-globin genes in transgenic mice EMBO J 4 1985 1715 1723
    • (1985) EMBO J , vol.4 , pp. 1715-1723
    • Townes, TM1    Lingrel, JB2    Chen, HY3    Brinster, RL4    Palmiter, RD5
  • 18
    • 0021810522 scopus 로고
    • Developmental regulation of a cloned adult β-globin gene in transgenic mice
    • Magram J Chada K Costantini F Developmental regulation of a cloned adult β-globin gene in transgenic mice Nature 315 1985 338 340
    • (1985) Nature , vol.315 , pp. 338-340
    • Magram, J1    Chada, K2    Costantini, F3
  • 19
    • 0029670543 scopus 로고    scopus 로고
    • Position effects and genetic disease
    • Milot E Fraser P Grosveld F Position effects and genetic disease Trends Genet 12 1996 123 126
    • (1996) Trends Genet , vol.12 , pp. 123-126
    • Milot, E1    Fraser, P2    Grosveld, F3
  • 20
    • 0026027982 scopus 로고
    • A position effect assay for boundaries of higher order chromosomal domains
    • Kellum R Schedl P A position effect assay for boundaries of higher order chromosomal domains Cell 64 1991 941 950
    • (1991) Cell , vol.64 , pp. 941-950
    • Kellum, R1    Schedl, P2
  • 21
    • 0028138645 scopus 로고
    • Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice
    • Bonifer C Yannoutsos N Kruger G Grosveld F Sippel AE Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice Nucleic Acids Res 22 1994 4202 4210
    • (1994) Nucleic Acids Res , vol.22 , pp. 4202-4210
    • Bonifer, C1    Yannoutsos, N2    Kruger, G3    Grosveld, F4    Sippel, AE5
  • 22
    • 0032530174 scopus 로고    scopus 로고
    • Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators
    • Pikaart MJ Recillas-Targa F Felsenfeld G Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators Genes Dev 12 1998 2852 2862
    • (1998) Genes Dev , vol.12 , pp. 2852-2862
    • Pikaart, MJ1    Recillas-Targa, F2    Felsenfeld, G3
  • 24
    • 0030298416 scopus 로고    scopus 로고
    • The vagaries of variegating transgenes
    • Martin D Whitelaw E The vagaries of variegating transgenes Bioessays 18 1996 919 923
    • (1996) Bioessays , vol.18 , pp. 919-923
    • Martin, D1    Whitelaw, E2
  • 25
    • 0027211845 scopus 로고
    • A novel erythroid cell specific murine transcription factor that binds to the CACCC elements and is related to the Kruppel family of nuclear proteins
    • Miller I Bieker J A novel erythroid cell specific murine transcription factor that binds to the CACCC elements and is related to the Kruppel family of nuclear proteins Mol Cell Biol 13 1993 2776 2786
    • (1993) Mol Cell Biol , vol.13 , pp. 2776-2786
    • Miller, I1    Bieker, J2
  • 26
    • 0029861514 scopus 로고    scopus 로고
    • Silencing of fetal human globin expression is impaired in the absemce of the adult β globin activator protein EKLF
    • Perkins A Gaensler K Orkin S Silencing of fetal human globin expression is impaired in the absemce of the adult β globin activator protein EKLF Proc Natl Acad Sci USA 93 1996 12267 12271
    • (1996) , pp. 12267-12271
    • Perkins, A1    Gaensler, K2    Orkin, S3
  • 28
    • 0032530169 scopus 로고    scopus 로고
    • Altered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the beta-globin locus control region in vivo
    • Gillemans N Tewari R Lindeboom F Rottier R de Wit T Wijgerde M Grosveld F Philipsen S Altered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the beta-globin locus control region in vivo Genes Dev 12 1998 2863 2873 •• of outstanding interest
    • (1998) Genes Dev , vol.12 , pp. 2863-2873
    • Gillemans, N1    Tewari, R2    Lindeboom, F3    Rottier, R4    de Wit, T5    Wijgerde, M6    Grosveld, F7    Philipsen, S8
  • 29
    • 0032475845 scopus 로고    scopus 로고
    • A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissuespecific transcriptional regulation by EKLF in vitro
    • Armstrong JA Bieker JJ Emerson BM A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissuespecific transcriptional regulation by EKLF in vitro Cell 5 1998 93 104 •• of outstanding interest
    • (1998) Cell , vol.5 , pp. 93-104
    • Armstrong, JA1    Bieker, JJ2    Emerson, BM3
  • 30
    • 0027305095 scopus 로고
    • An ‘in-out’ strategy using targeted FLP recombinase for the functional dissection of complex regulatory elements: analysis of the β-globin locus control region
    • Fiering S Kirn C Epner E Groudine M An ‘in-out’ strategy using targeted FLP recombinase for the functional dissection of complex regulatory elements: analysis of the β-globin locus control region Proc Natl Acad Sci USA 90 1993 8469 8473
    • (1993) , pp. 8469-8473
    • Fiering, S1    Kirn, C2    Epner, E3    Groudine, M4
  • 31
    • 0029091902 scopus 로고
    • Targeted deletion of 5′HS2 of the murine β-globin LCR reveals that it is not essential for the regulation of the β-globin locus
    • Fiering S Epner E Robinson K Zhuang Y Telling A Hu M Martin D Enver T Groudine M Targeted deletion of 5′HS2 of the murine β-globin LCR reveals that it is not essential for the regulation of the β-globin locus Genes Dev 9 1995 2203 2213
    • (1995) Genes Dev , vol.9 , pp. 2203-2213
    • Fiering, S1    Epner, E2    Robinson, K3    Zhuang, Y4    Telling, A5    Hu, M6    Martin, D7    Enver, T8    Groudine, M9
  • 32
    • 0029954767 scopus 로고    scopus 로고
    • Analysis of mice containing a targeted deletion of β-globin locus control region 5′ hypersensitive site 3
    • Hug B Wesselschmidt R Ffiering S Bender M Epner E Groudine M Ley T Analysis of mice containing a targeted deletion of β-globin locus control region 5′ hypersensitive site 3 Mol Cell Biol 16 1996 2906 2912
    • (1996) Mol Cell Biol , vol.16 , pp. 2906-2912
    • Hug, B1    Wesselschmidt, R2    Ffiering, S3    Bender, M4    Epner, E5    Groudine, M6    Ley, T7
  • 33
    • 0031708415 scopus 로고    scopus 로고
    • The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells
    • Reik A Telling A Zitnik G Cimbora D Epner E Groudine M The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells Mol Cell Biol 18 1998 5992 6000 •• of outstanding interest
    • (1998) Mol Cell Biol , vol.18 , pp. 5992-6000
    • Reik, A1    Telling, A2    Zitnik, G3    Cimbora, D4    Epner, E5    Groudine, M6
  • 34
    • 0032185226 scopus 로고    scopus 로고
    • The β-globin LCR is not required for an open chromatin structure or developmentally regulated transcription of the native mouse β-globin locus
    • Epner E Reik A Cimbora D Telling A Bender M Fiering S Enver T Martin D Kennedy M Keller G Groudine M The β-globin LCR is not required for an open chromatin structure or developmentally regulated transcription of the native mouse β-globin locus Mol Cell 2 1998 447 455 •• of outstanding interest
    • (1998) Mol Cell , vol.2 , pp. 447-455
    • Epner, E1    Reik, A2    Cimbora, D3    Telling, A4    Bender, M5    Fiering, S6    Enver, T7    Martin, D8    Kennedy, M9    Keller, G10    Groudine, M11
  • 35
    • 0029957832 scopus 로고    scopus 로고
    • Effect of deletion of HS3 or HS2 of the human β-globin locus control regioin on the developmnetal regulation of globin gene expression in β-globin locus YAC transgenic mice
    • Peterson KR Clegg C Navas P Norton E Kimrough T Stamatoyannopoulos G Effect of deletion of HS3 or HS2 of the human β-globin locus control regioin on the developmnetal regulation of globin gene expression in β-globin locus YAC transgenic mice Proc Natl Acad Sci USA 93 1996 6605 6609
    • (1996) , pp. 6605-6609
    • Peterson, KR1    Clegg, C2    Navas, P3    Norton, E4    Kimrough, T5    Stamatoyannopoulos, G6
  • 36
    • 0029558513 scopus 로고
    • Synergistic regulation of human β-globin gene switching by LCR elements HS3 and HS4
    • Bungert J Dave U Lim K Lieuw K Shavit J Liu Q Engel D Synergistic regulation of human β-globin gene switching by LCR elements HS3 and HS4 Genes Dev 9 1995 3083 3096
    • (1995) Genes Dev , vol.9 , pp. 3083-3096
    • Bungert, J1    Dave, U2    Lim, K3    Lieuw, K4    Shavit, J5    Liu, Q6    Engel, D7
  • 37
    • 0024747815 scopus 로고
    • High level, erythroid specific, expression of the human β globin gene in transgenic mice and the production of human hemoglobin I murine erythrocytes Genes
    • Hanscombe O Vidai M Kaeda J Luzzatto L Greaves D Grosveld F High level, erythroid specific, expression of the human β globin gene in transgenic mice and the production of human hemoglobin I murine erythrocytes Genes Dev 3 1989 1572 1581
    • (1989) Dev , vol.3 , pp. 1572-1581
    • Hanscombe, O1    Vidai, M2    Kaeda, J3    Luzzatto, L4    Greaves, D5    Grosveld, F6
  • 38
    • 0029051646 scopus 로고
    • Transcription complex stability and chromatin dynamics in vivo
    • Wijgerde M Grosveld F Fraser P Transcription complex stability and chromatin dynamics in vivo Nature 377 1995 209 213
    • (1995) Nature , vol.377 , pp. 209-213
    • Wijgerde, M1    Grosveld, F2    Fraser, P3
  • 39
    • 0027202509 scopus 로고
    • Developmental regulation of human β-globin gene transcription: a switch of loyalties?
    • Engel JD Developmental regulation of human β-globin gene transcription: a switch of loyalties? Trends Genet 9 1993 304 309
    • (1993) Trends Genet , vol.9 , pp. 304-309
    • Engel, JD1
  • 40
    • 0030219342 scopus 로고    scopus 로고
    • Regulation of β-globin gene expression: straightening out the locus
    • Martin DIK Fiering S Groudine M Regulation of β-globin gene expression: straightening out the locus Curr Opin Genet Dev 6 1996 488 495
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 488-495
    • Martin, DIK1    Fiering, S2    Groudine, M3
  • 41
    • 85119798153 scopus 로고
    • Mutational analysis of the β-globin locus control region. Initiation region interaction
    • Epner E Aladjem M Dicken E Fournier K Fiering S Wahl G Groudine M Mutational analysis of the β-globin locus control region. Initiation region interaction Blood 86 Suppl 1 1995 7a
    • (1995) Blood , vol.86 , Issue.Suppl 1 , pp. 7a
    • Epner, E1    Aladjem, M2    Dicken, E3    Fournier, K4    Fiering, S5    Wahl, G6    Groudine, M7
  • 42
    • 0032524877 scopus 로고    scopus 로고
    • The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis
    • Cavalli G Paro R The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis Cell 93 1998 505 518
    • (1998) Cell , vol.93 , pp. 505-518
    • Cavalli, G1    Paro, R2
  • 43
    • 0030743612 scopus 로고    scopus 로고
    • DNA methylation and imprinting: why bother?
    • Jaenish R DNA methylation and imprinting: why bother? Trends Genet 13 1997 323 329
    • (1997) Trends Genet , vol.13 , pp. 323-329
    • Jaenish, R1
  • 44
    • 0023815070 scopus 로고
    • Dosage dependent modifiers of PEV in Drosophila and a mass action model that explains their effect
    • Locke J Kotarski M Tartof K Dosage dependent modifiers of PEV in Drosophila and a mass action model that explains their effect Genetics 120 1988 181 198
    • (1988) Genetics , vol.120 , pp. 181-198
    • Locke, J1    Kotarski, M2    Tartof, K3
  • 45
    • 0030826364 scopus 로고    scopus 로고
    • Intergenic transcription and transduction of the human β-globin locus
    • Ashe H Monks J Wijgerde M Fraser P Proudfoot N Intergenic transcription and transduction of the human β-globin locus Genes Dev 11 1997 2494 2509
    • (1997) Genes Dev , vol.11 , pp. 2494-2509
    • Ashe, H1    Monks, J2    Wijgerde, M3    Fraser, P4    Proudfoot, N5


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