-
1
-
-
0023663887
-
Positionindependent, high-level expression of the human β-globin gene in transgenic mice
-
Grosveld F Blom van Assendelft G Greaves DR Kollias G Positionindependent, high-level expression of the human β-globin gene in transgenic mice Cell 51 1987 975 985
-
(1987)
Cell
, vol.51
, pp. 975-985
-
-
Grosveld, F1
Blom van Assendelft, G2
Greaves, DR3
Kollias, G4
-
2
-
-
0021014396
-
Beta-globin gene inactivation by DNA translocation in γβ-thalassemia
-
Kioussis D Vanin E deLange T Flavell RA Grosveld FG Beta-globin gene inactivation by DNA translocation in γβ-thalassemia Nature 306 1983 662 666
-
(1983)
Nature
, vol.306
, pp. 662-666
-
-
Kioussis, D1
Vanin, E2
deLange, T3
Flavell, RA4
Grosveld, FG5
-
3
-
-
0012953756
-
γδβ thalassemia due to a de novo mutation deleting the 5′ β-globin gene activation region hypersensitive sites
-
Driscoll M Dobkin C Alter B γδβ thalassemia due to a de novo mutation deleting the 5′ β-globin gene activation region hypersensitive sites Proc Natl Acad Sci USA 86 1989 7470 7474
-
(1989)
, pp. 7470-7474
-
-
Driscoll, M1
Dobkin, C2
Alter, B3
-
5
-
-
85119794677
-
Hemoglobin switching
-
in press Grosveld F Stamatoyannopoulos G Hemoglobin switching The Molecular Basis of Blood Diseases 1999 WB Saunders Company Philadelphia
-
(1999)
-
-
Grosveld, F1
Stamatoyannopoulos, G2
-
6
-
-
0344272073
-
The β-like globin domain in human erythroid cells
-
Tuan D Solomon W Li Q London I The β-like globin domain in human erythroid cells Proc Natl Acad Sci USA 82 1985 6384 6388
-
(1985)
, pp. 6384-6388
-
-
Tuan, D1
Solomon, W2
Li, Q3
London, I4
-
7
-
-
0022450433
-
A developmentally stable chromatin structure in the human β-globin cluster
-
Forrester W Thompson C Elder J Groudine M A developmentally stable chromatin structure in the human β-globin cluster Proc Natl Acad Sci USA 83 1986 1359 1363
-
(1986)
, pp. 1359-1363
-
-
Forrester, W1
Thompson, C2
Elder, J3
Groudine, M4
-
8
-
-
0024558096
-
Human CD2 3′-flanking sequences confer high-level, T cell-specific, positionindependent gene expression in transgenic mice
-
Greaves DR Wilson FD Lang G Kioussis D Human CD2 3′-flanking sequences confer high-level, T cell-specific, positionindependent gene expression in transgenic mice Cell 56 1989 979 986
-
(1989)
Cell
, vol.56
, pp. 979-986
-
-
Greaves, DR1
Wilson, FD2
Lang, G3
Kioussis, D4
-
9
-
-
0030726908
-
Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals
-
Kioussis D Festenstein R Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals Curr Opin Genet Dev 7 1997 614 619
-
(1997)
Curr Opin Genet Dev
, vol.7
, pp. 614-619
-
-
Kioussis, D1
Festenstein, R2
-
10
-
-
0029912235
-
Locus control region function and heterochromatin-induced position effect variegation
-
Festenstein R Toliani M Corbella P Mamalaki C Parrington J Fox M Jones M Kioussis D Locus control region function and heterochromatin-induced position effect variegation Science 271 1996 1123 1125
-
(1996)
Science
, vol.271
, pp. 1123-1125
-
-
Festenstein, R1
Toliani, M2
Corbella, P3
Mamalaki, C4
Parrington, J5
Fox, M6
Jones, M7
Kioussis, D8
-
11
-
-
16044372786
-
Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription
-
Milot E Stouboulis J Trimborn T Wijgerde M de Boer E Langeveld A Tan-Un K Vergeer W Yannoutsos N Grosveld F Fraser P Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription Cell 87 1996 105 114
-
(1996)
Cell
, vol.87
, pp. 105-114
-
-
Milot, E1
Stouboulis, J2
Trimborn, T3
Wijgerde, M4
de Boer, E5
Langeveld, A6
Tan-Un, K7
Vergeer, W8
Yannoutsos, N9
Grosveld, F10
Fraser, P11
-
12
-
-
0025107556
-
A deletion of the human betaglobin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus
-
Forrester WC Epner E Driscoll MC Enver T Brice M Papayannopoulou T Groudine M A deletion of the human betaglobin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus Genes Dev 4 1990 1637 1649
-
(1990)
Genes Dev
, vol.4
, pp. 1637-1649
-
-
Forrester, WC1
Epner, E2
Driscoll, MC3
Enver, T4
Brice, M5
Papayannopoulou, T6
Groudine, M7
-
14
-
-
0022549802
-
Regulated expression of human A gamma-, beta-, and hybrid gamma beta-globin genes in transgenic mice: manipulation of the developmental expression patterns
-
Kollias G Wrighton N Hurst J Grosveld F Regulated expression of human A gamma-, beta-, and hybrid gamma beta-globin genes in transgenic mice: manipulation of the developmental expression patterns Cell 46 1986 89 94
-
(1986)
Cell
, vol.46
, pp. 89-94
-
-
Kollias, G1
Wrighton, N2
Hurst, J3
Grosveld, F4
-
15
-
-
0023442125
-
A 3′ enhancer contributes to the stage specific expression of the human β-globin gene
-
Trudel M Costantini F A 3′ enhancer contributes to the stage specific expression of the human β-globin gene Genes Dev 1 1987 954 961
-
(1987)
Genes Dev
, vol.1
, pp. 954-961
-
-
Trudel, M1
Costantini, F2
-
16
-
-
0023547189
-
Two 3′ sequences direct adult erythroid specific expression of human β-globin genes in mice
-
Behringer R Hammer R Brinster R Palmiter R Townes T Two 3′ sequences direct adult erythroid specific expression of human β-globin genes in mice Proc Natl Acad Sci USA 84 1987 7056 7060
-
(1987)
, pp. 7056-7060
-
-
Behringer, R1
Hammer, R2
Brinster, R3
Palmiter, R4
Townes, T5
-
17
-
-
0022100680
-
Erythroid-specific expression of human beta-globin genes in transgenic mice
-
Townes TM Lingrel JB Chen HY Brinster RL Palmiter RD Erythroid-specific expression of human beta-globin genes in transgenic mice EMBO J 4 1985 1715 1723
-
(1985)
EMBO J
, vol.4
, pp. 1715-1723
-
-
Townes, TM1
Lingrel, JB2
Chen, HY3
Brinster, RL4
Palmiter, RD5
-
18
-
-
0021810522
-
Developmental regulation of a cloned adult β-globin gene in transgenic mice
-
Magram J Chada K Costantini F Developmental regulation of a cloned adult β-globin gene in transgenic mice Nature 315 1985 338 340
-
(1985)
Nature
, vol.315
, pp. 338-340
-
-
Magram, J1
Chada, K2
Costantini, F3
-
19
-
-
0029670543
-
Position effects and genetic disease
-
Milot E Fraser P Grosveld F Position effects and genetic disease Trends Genet 12 1996 123 126
-
(1996)
Trends Genet
, vol.12
, pp. 123-126
-
-
Milot, E1
Fraser, P2
Grosveld, F3
-
20
-
-
0026027982
-
A position effect assay for boundaries of higher order chromosomal domains
-
Kellum R Schedl P A position effect assay for boundaries of higher order chromosomal domains Cell 64 1991 941 950
-
(1991)
Cell
, vol.64
, pp. 941-950
-
-
Kellum, R1
Schedl, P2
-
21
-
-
0028138645
-
Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice
-
Bonifer C Yannoutsos N Kruger G Grosveld F Sippel AE Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice Nucleic Acids Res 22 1994 4202 4210
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4202-4210
-
-
Bonifer, C1
Yannoutsos, N2
Kruger, G3
Grosveld, F4
Sippel, AE5
-
22
-
-
0032530174
-
Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators
-
Pikaart MJ Recillas-Targa F Felsenfeld G Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators Genes Dev 12 1998 2852 2862
-
(1998)
Genes Dev
, vol.12
, pp. 2852-2862
-
-
Pikaart, MJ1
Recillas-Targa, F2
Felsenfeld, G3
-
24
-
-
0030298416
-
The vagaries of variegating transgenes
-
Martin D Whitelaw E The vagaries of variegating transgenes Bioessays 18 1996 919 923
-
(1996)
Bioessays
, vol.18
, pp. 919-923
-
-
Martin, D1
Whitelaw, E2
-
25
-
-
0027211845
-
A novel erythroid cell specific murine transcription factor that binds to the CACCC elements and is related to the Kruppel family of nuclear proteins
-
Miller I Bieker J A novel erythroid cell specific murine transcription factor that binds to the CACCC elements and is related to the Kruppel family of nuclear proteins Mol Cell Biol 13 1993 2776 2786
-
(1993)
Mol Cell Biol
, vol.13
, pp. 2776-2786
-
-
Miller, I1
Bieker, J2
-
26
-
-
0029861514
-
Silencing of fetal human globin expression is impaired in the absemce of the adult β globin activator protein EKLF
-
Perkins A Gaensler K Orkin S Silencing of fetal human globin expression is impaired in the absemce of the adult β globin activator protein EKLF Proc Natl Acad Sci USA 93 1996 12267 12271
-
(1996)
, pp. 12267-12271
-
-
Perkins, A1
Gaensler, K2
Orkin, S3
-
28
-
-
0032530169
-
Altered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the beta-globin locus control region in vivo
-
Gillemans N Tewari R Lindeboom F Rottier R de Wit T Wijgerde M Grosveld F Philipsen S Altered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the beta-globin locus control region in vivo Genes Dev 12 1998 2863 2873 •• of outstanding interest
-
(1998)
Genes Dev
, vol.12
, pp. 2863-2873
-
-
Gillemans, N1
Tewari, R2
Lindeboom, F3
Rottier, R4
de Wit, T5
Wijgerde, M6
Grosveld, F7
Philipsen, S8
-
29
-
-
0032475845
-
A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissuespecific transcriptional regulation by EKLF in vitro
-
Armstrong JA Bieker JJ Emerson BM A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissuespecific transcriptional regulation by EKLF in vitro Cell 5 1998 93 104 •• of outstanding interest
-
(1998)
Cell
, vol.5
, pp. 93-104
-
-
Armstrong, JA1
Bieker, JJ2
Emerson, BM3
-
30
-
-
0027305095
-
An ‘in-out’ strategy using targeted FLP recombinase for the functional dissection of complex regulatory elements: analysis of the β-globin locus control region
-
Fiering S Kirn C Epner E Groudine M An ‘in-out’ strategy using targeted FLP recombinase for the functional dissection of complex regulatory elements: analysis of the β-globin locus control region Proc Natl Acad Sci USA 90 1993 8469 8473
-
(1993)
, pp. 8469-8473
-
-
Fiering, S1
Kirn, C2
Epner, E3
Groudine, M4
-
31
-
-
0029091902
-
Targeted deletion of 5′HS2 of the murine β-globin LCR reveals that it is not essential for the regulation of the β-globin locus
-
Fiering S Epner E Robinson K Zhuang Y Telling A Hu M Martin D Enver T Groudine M Targeted deletion of 5′HS2 of the murine β-globin LCR reveals that it is not essential for the regulation of the β-globin locus Genes Dev 9 1995 2203 2213
-
(1995)
Genes Dev
, vol.9
, pp. 2203-2213
-
-
Fiering, S1
Epner, E2
Robinson, K3
Zhuang, Y4
Telling, A5
Hu, M6
Martin, D7
Enver, T8
Groudine, M9
-
32
-
-
0029954767
-
Analysis of mice containing a targeted deletion of β-globin locus control region 5′ hypersensitive site 3
-
Hug B Wesselschmidt R Ffiering S Bender M Epner E Groudine M Ley T Analysis of mice containing a targeted deletion of β-globin locus control region 5′ hypersensitive site 3 Mol Cell Biol 16 1996 2906 2912
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2906-2912
-
-
Hug, B1
Wesselschmidt, R2
Ffiering, S3
Bender, M4
Epner, E5
Groudine, M6
Ley, T7
-
33
-
-
0031708415
-
The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells
-
Reik A Telling A Zitnik G Cimbora D Epner E Groudine M The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells Mol Cell Biol 18 1998 5992 6000 •• of outstanding interest
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5992-6000
-
-
Reik, A1
Telling, A2
Zitnik, G3
Cimbora, D4
Epner, E5
Groudine, M6
-
34
-
-
0032185226
-
The β-globin LCR is not required for an open chromatin structure or developmentally regulated transcription of the native mouse β-globin locus
-
Epner E Reik A Cimbora D Telling A Bender M Fiering S Enver T Martin D Kennedy M Keller G Groudine M The β-globin LCR is not required for an open chromatin structure or developmentally regulated transcription of the native mouse β-globin locus Mol Cell 2 1998 447 455 •• of outstanding interest
-
(1998)
Mol Cell
, vol.2
, pp. 447-455
-
-
Epner, E1
Reik, A2
Cimbora, D3
Telling, A4
Bender, M5
Fiering, S6
Enver, T7
Martin, D8
Kennedy, M9
Keller, G10
Groudine, M11
-
35
-
-
0029957832
-
Effect of deletion of HS3 or HS2 of the human β-globin locus control regioin on the developmnetal regulation of globin gene expression in β-globin locus YAC transgenic mice
-
Peterson KR Clegg C Navas P Norton E Kimrough T Stamatoyannopoulos G Effect of deletion of HS3 or HS2 of the human β-globin locus control regioin on the developmnetal regulation of globin gene expression in β-globin locus YAC transgenic mice Proc Natl Acad Sci USA 93 1996 6605 6609
-
(1996)
, pp. 6605-6609
-
-
Peterson, KR1
Clegg, C2
Navas, P3
Norton, E4
Kimrough, T5
Stamatoyannopoulos, G6
-
36
-
-
0029558513
-
Synergistic regulation of human β-globin gene switching by LCR elements HS3 and HS4
-
Bungert J Dave U Lim K Lieuw K Shavit J Liu Q Engel D Synergistic regulation of human β-globin gene switching by LCR elements HS3 and HS4 Genes Dev 9 1995 3083 3096
-
(1995)
Genes Dev
, vol.9
, pp. 3083-3096
-
-
Bungert, J1
Dave, U2
Lim, K3
Lieuw, K4
Shavit, J5
Liu, Q6
Engel, D7
-
37
-
-
0024747815
-
High level, erythroid specific, expression of the human β globin gene in transgenic mice and the production of human hemoglobin I murine erythrocytes Genes
-
Hanscombe O Vidai M Kaeda J Luzzatto L Greaves D Grosveld F High level, erythroid specific, expression of the human β globin gene in transgenic mice and the production of human hemoglobin I murine erythrocytes Genes Dev 3 1989 1572 1581
-
(1989)
Dev
, vol.3
, pp. 1572-1581
-
-
Hanscombe, O1
Vidai, M2
Kaeda, J3
Luzzatto, L4
Greaves, D5
Grosveld, F6
-
38
-
-
0029051646
-
Transcription complex stability and chromatin dynamics in vivo
-
Wijgerde M Grosveld F Fraser P Transcription complex stability and chromatin dynamics in vivo Nature 377 1995 209 213
-
(1995)
Nature
, vol.377
, pp. 209-213
-
-
Wijgerde, M1
Grosveld, F2
Fraser, P3
-
39
-
-
0027202509
-
Developmental regulation of human β-globin gene transcription: a switch of loyalties?
-
Engel JD Developmental regulation of human β-globin gene transcription: a switch of loyalties? Trends Genet 9 1993 304 309
-
(1993)
Trends Genet
, vol.9
, pp. 304-309
-
-
Engel, JD1
-
40
-
-
0030219342
-
Regulation of β-globin gene expression: straightening out the locus
-
Martin DIK Fiering S Groudine M Regulation of β-globin gene expression: straightening out the locus Curr Opin Genet Dev 6 1996 488 495
-
(1996)
Curr Opin Genet Dev
, vol.6
, pp. 488-495
-
-
Martin, DIK1
Fiering, S2
Groudine, M3
-
41
-
-
85119798153
-
Mutational analysis of the β-globin locus control region. Initiation region interaction
-
Epner E Aladjem M Dicken E Fournier K Fiering S Wahl G Groudine M Mutational analysis of the β-globin locus control region. Initiation region interaction Blood 86 Suppl 1 1995 7a
-
(1995)
Blood
, vol.86
, Issue.Suppl 1
, pp. 7a
-
-
Epner, E1
Aladjem, M2
Dicken, E3
Fournier, K4
Fiering, S5
Wahl, G6
Groudine, M7
-
42
-
-
0032524877
-
The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis
-
Cavalli G Paro R The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis Cell 93 1998 505 518
-
(1998)
Cell
, vol.93
, pp. 505-518
-
-
Cavalli, G1
Paro, R2
-
43
-
-
0030743612
-
DNA methylation and imprinting: why bother?
-
Jaenish R DNA methylation and imprinting: why bother? Trends Genet 13 1997 323 329
-
(1997)
Trends Genet
, vol.13
, pp. 323-329
-
-
Jaenish, R1
-
44
-
-
0023815070
-
Dosage dependent modifiers of PEV in Drosophila and a mass action model that explains their effect
-
Locke J Kotarski M Tartof K Dosage dependent modifiers of PEV in Drosophila and a mass action model that explains their effect Genetics 120 1988 181 198
-
(1988)
Genetics
, vol.120
, pp. 181-198
-
-
Locke, J1
Kotarski, M2
Tartof, K3
-
45
-
-
0030826364
-
Intergenic transcription and transduction of the human β-globin locus
-
Ashe H Monks J Wijgerde M Fraser P Proudfoot N Intergenic transcription and transduction of the human β-globin locus Genes Dev 11 1997 2494 2509
-
(1997)
Genes Dev
, vol.11
, pp. 2494-2509
-
-
Ashe, H1
Monks, J2
Wijgerde, M3
Fraser, P4
Proudfoot, N5
|