Correction of the sickle cell mutation in embryonic stem cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 4, 2006, Pages 1036-1040

  Chang, Judy C ^a   Ye, Lin ^a   Kan, Yuet Wai ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

thalassemia; Correction of mutation; Hematopoietic differentiation; Homologous recombination; Sickle cell anemia

Indexed keywords

BETA GLOBIN; HEMOGLOBIN A; HEMOGLOBIN S;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA THALASSEMIA; BLASTOCYST; BONE MARROW TRANSPLANTATION; CARDIOPULMONARY INSUFFICIENCY; CELL DIFFERENTIATION; CLONING; CONTROLLED STUDY; DNA SEQUENCE; EMBRYONIC STEM CELL; FEASIBILITY STUDY; GENE MUTATION; GENOTYPE; HEMATOPOIETIC CELL; HISTOCOMPATIBILITY; HOMOLOGOUS RECOMBINATION; INFECTION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUALITY OF LIFE; SICKLE CELL ANEMIA; STROKE; SURVIVAL; TECHNOLOGY; TRANSGENIC MOUSE; TREATMENT INDICATION;

ANEMIA, SICKLE CELL; ANIMALS; BETA-THALASSEMIA; BLASTOCYST; BLOTTING, SOUTHERN; CELL DIFFERENTIATION; CELL LINE; EMBRYO; GENETIC VECTORS; GENOTYPE; GLOBINS; HEMATOPOIETIC STEM CELLS; HEMOGLOBIN A; HEMOGLOBIN, SICKLE; HEMOGLOBINS; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; MUTATION; RECOMBINATION, GENETIC; STEM CELLS; TRANSGENES;

ANIMALIA; MUS MUSCULUS;

EID: 32244434403     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510177103     Document Type: Article

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