The 5′HS4 core element of the human β-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis

Journal of Molecular Biology

Volumn 312, Issue 1, 2001, Pages 17-26

  Navas, Patrick A ^a   Peterson, Kenneth R ^b   Li, Qiliang ^a   McArthur, Michael ^a   Stamatoyannopoulos, George ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Developmental regulation; DNase I hypersensitive sites; Locus control region; YAC transgenic mice; globin

Indexed keywords

BETA GLOBIN; DEOXYRIBONUCLEASE I; DEOXYRIBONUCLEASE I HYPERSENSITIVE SITE 4; GAMMA GLOBIN; TYPE I SITE SPECIFIC DEOXYRIBONUCLEASE; UNCLASSIFIED DRUG; GLOBIN;

ADULT; ARTICLE; BINDING SITE; CHROMATIN STRUCTURE; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; ERYTHROID CELL; ERYTHROPOIESIS; FETUS LIVER; GENE DELETION; GENE DUPLICATION; GENE EXPRESSION; GENE LOCUS; GENE STRUCTURE; HUMAN; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATOR GENE; TRANSGENIC MOUSE; YEAST ARTIFICIAL CHROMOSOME; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; LIVER; METABOLISM; PRENATAL DEVELOPMENT; REGULATORY SEQUENCE;

MUS MUSCULUS;

ANIMALS; CHROMOSOMES, ARTIFICIAL, YEAST; DEOXYRIBONUCLEASE I; ERYTHROPOIESIS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLOBINS; HUMANS; LIVER; MICE; MICE, TRANSGENIC; REGULATORY SEQUENCES, NUCLEIC ACID; SEQUENCE DELETION;

EID: 0035822898     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4939     Document Type: Article

References (35)

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