-
1
-
-
0025228661
-
Human γ- To β-globin gene switching in transgenic mice
-
Behringer, R. R., T. M. Ryan, R. D. Palmiter, R. L. Brinster, and T. M. Townes. 1990. Human γ- to β-globin gene switching in transgenic mice. Genes Dev. 4:380-389.
-
(1990)
Genes Dev.
, vol.4
, pp. 380-389
-
-
Behringer, R.R.1
Ryan, T.M.2
Palmiter, R.D.3
Brinster, R.L.4
Townes, T.M.5
-
2
-
-
0029558513
-
Synergistic regulation of human β-globin gene switching by locus control region elements HS3 and HS4
-
Bungert, J., U. Dave, K. C. Lim, K. Lieuw, J. Shavit, Q. Liu, and J. Engel. 1995. Synergistic regulation of human β-globin gene switching by locus control region elements HS3 and HS4. Genes Dev. 9:3083-3096.
-
(1995)
Genes Dev.
, vol.9
, pp. 3083-3096
-
-
Bungert, J.1
Dave, U.2
Lim, K.C.3
Lieuw, K.4
Shavit, J.5
Liu, Q.6
Engel, J.7
-
3
-
-
0022600521
-
An embryonic pattern of expression of a human fetal globin gene in transgenic mice
-
Chada, K., J. Magram, and F. Costantini. 1986. An embryonic pattern of expression of a human fetal globin gene in transgenic mice. Nature (London) 319:685-688.
-
(1986)
Nature (London)
, vol.319
, pp. 685-688
-
-
Chada, K.1
Magram, J.2
Costantini, F.3
-
4
-
-
0021911408
-
Specific expression of a foreign β-globin gene in erythroid cells of transgenic mice
-
Chada, K., J. Magram, K. Raphael, G. Radice, E. Lacy, and F. Costantini. 1985. Specific expression of a foreign β-globin gene in erythroid cells of transgenic mice. Nature (London) 314:377-380.
-
(1985)
Nature (London)
, vol.314
, pp. 377-380
-
-
Chada, K.1
Magram, J.2
Raphael, K.3
Radice, G.4
Lacy, E.5
Costantini, F.6
-
5
-
-
0025370230
-
Erythroid-specific nuclease-hypersensitive sites flanking the human β-globin domain
-
Dhar, V., A. Nandi, C. L. Schildkraul, and A. Skoultchi. 1990. Erythroid-specific nuclease-hypersensitive sites flanking the human β-globin domain. Mol. Cell. Biol. 10:4324-4333.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 4324-4333
-
-
Dhar, V.1
Nandi, A.2
Schildkraul, C.L.3
Skoultchi, A.4
-
6
-
-
0025891950
-
Human γ-globin genes silenced independently of other genes in the β-globin locus
-
Dillon, N., and F. Grosveld. 1991. Human γ-globin genes silenced independently of other genes in the β-globin locus. Nature (London) 350:252-254.
-
(1991)
Nature (London)
, vol.350
, pp. 252-254
-
-
Dillon, N.1
Grosveld, F.2
-
7
-
-
0012953756
-
γδβ-Thalassemia due to a de novo mutation deleting the 5′ β-globin gene activation-region hypersensitive sites
-
Driscoll, M., C. Dobkin, and B. Alter. 1989. γδβ-Thalassemia due to a de novo mutation deleting the 5′ β-globin gene activation-region hypersensitive sites. Proc. Natl. Acad. Sci. USA 86:7470-7474.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7470-7474
-
-
Driscoll, M.1
Dobkin, C.2
Alter, B.3
-
8
-
-
0030050402
-
A dominant chromatin opening activity in 5′ hypersensitive site 3 of the human β-globin locus control region
-
7a.Ellis, J., K. C. Tan-Un, A. Harper, D. Michalovich, N. Yannoutsos, S. Philipsen, and F. Grosveld. 1996. A dominant chromatin opening activity in 5′ hypersensitive site 3 of the human β-globin locus control region. EMBO J. 15:562-568.
-
(1996)
EMBO J.
, vol.15
, pp. 562-568
-
-
Ellis, J.1
Tan-Un, K.C.2
Harper, A.3
Michalovich, D.4
Yannoutsos, N.5
Philipsen, S.6
Grosveld, F.7
-
9
-
-
0025329590
-
Developmental regulation of human fetal-to adult globin gene switching in transgenic mice
-
Enver, T., N. Raich, A. J. Ebens, T. Papayannopoulou, F. Costantini, and G. Stamatoyannopoulos. 1990. Developmental regulation of human fetal-to adult globin gene switching in transgenic mice. Nature (London) 344:309-313.
-
(1990)
Nature (London)
, vol.344
, pp. 309-313
-
-
Enver, T.1
Raich, N.2
Ebens, A.J.3
Papayannopoulou, T.4
Costantini, F.5
Stamatoyannopoulos, G.6
-
10
-
-
0029091902
-
Targeted deletion of 5′ HS-2 of the murine β-globin LCR reveals that it is not essential for proper regulation of the β-globin locus
-
Fiering, S., E. Epner, K. Robinson, Y. Zhuang, A. Telling, M. Hu, D. I. K. Martin, T. Enver, T. J. Ley, and M. Groudine. 1995. Targeted deletion of 5′ HS-2 of the murine β-globin LCR reveals that it is not essential for proper regulation of the β-globin locus. Genes Dev. 9:2203-2213.
-
(1995)
Genes Dev.
, vol.9
, pp. 2203-2213
-
-
Fiering, S.1
Epner, E.2
Robinson, K.3
Zhuang, Y.4
Telling, A.5
Hu, M.6
Martin, D.I.K.7
Enver, T.8
Ley, T.J.9
Groudine, M.10
-
11
-
-
0027305095
-
An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: Analysis of the β-globin locus control region
-
Fiering, S., C. Kim, E. Epner, and M. Groudine. 1993. An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the β-globin locus control region. Proc. Natl. Acad. Sci. USA 90:8469-8473.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8469-8473
-
-
Fiering, S.1
Kim, C.2
Epner, E.3
Groudine, M.4
-
12
-
-
1842345950
-
Molecular analysis of the human β-globin locus activation region
-
Forrester, W., U. Novak, R. Gelinas, and M. Groudine. 1989. Molecular analysis of the human β-globin locus activation region. Proc. Natl. Acad. Sci. USA 86:5439-5443.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5439-5443
-
-
Forrester, W.1
Novak, U.2
Gelinas, R.3
Groudine, M.4
-
13
-
-
0022450433
-
A developmentally stable chromatin structure in the human β-globin gene cluster
-
Forrester, W. C., C. Thompson, J. T. Elder, and M. Groudine. 1986. A developmentally stable chromatin structure in the human β-globin gene cluster. Proc. Natl. Acad. Sci. USA 83:1359-1363.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 1359-1363
-
-
Forrester, W.C.1
Thompson, C.2
Elder, J.T.3
Groudine, M.4
-
14
-
-
0025369610
-
DNase1 hypersensitive sites 1, 2, and 3 of the human β-globin dominant control region direct position-independent expression
-
Fraser, P., J. Hurst, P. Collis, and F. Grosveld. 1990. DNase1 hypersensitive sites 1, 2, and 3 of the human β-globin dominant control region direct position-independent expression. Nucleic Acids Res. 18:3503-3507.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 3503-3507
-
-
Fraser, P.1
Hurst, J.2
Collis, P.3
Grosveld, F.4
-
15
-
-
0027417886
-
Each hypersensitive site of the human β-globin locus control region confers a different developmental pattern of expression on the globin genes
-
Fraser, P., S. Pruzina, M. Antoniou, and F. Grosveld. 1993. Each hypersensitive site of the human β-globin locus control region confers a different developmental pattern of expression on the globin genes. Genes Dev. 7:106-113.
-
(1993)
Genes Dev.
, vol.7
, pp. 106-113
-
-
Fraser, P.1
Pruzina, S.2
Antoniou, M.3
Grosveld, F.4
-
16
-
-
0027443269
-
Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human β-globin locus in transgenic mice
-
Gaensler, K., M. Kitamura, and Y. Kan. 1993. Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human β-globin locus in transgenic mice. Proc. Natl. Acad. Sci. USA 90:11381-11385.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11381-11385
-
-
Gaensler, K.1
Kitamura, M.2
Kan, Y.3
-
17
-
-
0023663887
-
Position-independent, high-level expression of the human β-globin gene in transgenic mice
-
Grosveld, F., G. van Assendelft, D. Greaves, and G. Kollias. 1987. Position-independent, high-level expression of the human β-globin gene in transgenic mice. Cell 51:975-985.
-
(1987)
Cell
, vol.51
, pp. 975-985
-
-
Grosveld, F.1
Van Assendelft, G.2
Greaves, D.3
Kollias, G.4
-
18
-
-
0027322429
-
Comparative analysis of the locus control region of the rabbit β-like globin gene cluster: HS3 increases transient expression of an embryonic ε-globin gene
-
Hardison, R.. J. Xu, J. Jackson, J. Mansberger, O. Selifonova, B. Crotch, J. Biesecker, H. Petryowska, and W. Miller. 1993. Comparative analysis of the locus control region of the rabbit β-like globin gene cluster: HS3 increases transient expression of an embryonic ε-globin gene. Nucleic Acids Res. 21: 1265-1272.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 1265-1272
-
-
Hardison, R.1
Xu, J.2
Jackson, J.3
Mansberger, J.4
Selifonova, O.5
Crotch, B.6
Biesecker, J.7
Petryowska, H.8
Miller, W.9
-
19
-
-
0026453360
-
Structure and function of the murine β-globin locus control region 5′ HS-3
-
Hug, B. A., A. M. Moon, and T. J. Ley. 1992. Structure and function of the murine β-globin locus control region 5′ HS-3. Nucleic Acids Res. 20:5771-5778.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 5771-5778
-
-
Hug, B.A.1
Moon, A.M.2
Ley, T.J.3
-
20
-
-
0026441126
-
The mouse β-globin locus control region: Hypersensitive sites 3 and 4
-
Jimenez, G., K. B. Gale, and T. Enver. 1992. The mouse β-globin locus control region: hypersensitive sites 3 and 4. Nucleic Acids Res. 20:5797-5803.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 5797-5803
-
-
Jimenez, G.1
Gale, K.B.2
Enver, T.3
-
21
-
-
0026704374
-
Inactivation of the human β-globin gene by targeted insertion into the β-globin locus control region
-
Kim, C., E. Epner, W. Forrester, and M. Groudine. 1992. Inactivation of the human β-globin gene by targeted insertion into the β-globin locus control region. Genes Dev. 6:928-938.
-
(1992)
Genes Dev.
, vol.6
, pp. 928-938
-
-
Kim, C.1
Epner, E.2
Forrester, W.3
Groudine, M.4
-
22
-
-
0026058715
-
The proximal element of the β globin locus control region is not functionally required in vivo
-
Kulozik, A. E., S. Bail, A. Bellan-Koch, C. R. Bartram, E. Kohne, and E. Kleihauer. 1991. The proximal element of the β globin locus control region is not functionally required in vivo. J. Clin. Invest. 87:2142-2146.
-
(1991)
J. Clin. Invest.
, vol.87
, pp. 2142-2146
-
-
Kulozik, A.E.1
Bail, S.2
Bellan-Koch, A.3
Bartram, C.R.4
Kohne, E.5
Kleihauer, E.6
-
23
-
-
0025155693
-
β-Globin locus activation regions: Conservation of organization, structure, and function
-
Li, Q., B. Zhou, P. Powers, T. Enver, and G. Stamatoyannopoulos. 1990. β-Globin locus activation regions: conservation of organization, structure, and function. Proc. Natl. Acad. Sci. USA 87:8207-8211.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 8207-8211
-
-
Li, Q.1
Zhou, B.2
Powers, P.3
Enver, T.4
Stamatoyannopoulos, G.5
-
24
-
-
0026101602
-
Primary structure of the goat β-globin locus control region
-
Li, Q., B. Zhou, P. Powers, T. Enver, and G. Stamatoyannopoulos. 1991. Primary structure of the goat β-globin locus control region. Genomics 9:488-499.
-
(1991)
Genomics
, vol.9
, pp. 488-499
-
-
Li, Q.1
Zhou, B.2
Powers, P.3
Enver, T.4
Stamatoyannopoulos, G.5
-
25
-
-
0021810522
-
Development regulation of a cloned adult β-globin gene in transgenic mice
-
Magram, J., K. Chada, and F. Costantini. 1985. Development regulation of a cloned adult β-globin gene in transgenic mice. Nature (London) 315:338-340.
-
(1985)
Nature (London)
, vol.315
, pp. 338-340
-
-
Magram, J.1
Chada, K.2
Costantini, F.3
-
26
-
-
11944256454
-
Conservation of the primary structure, organization, and function of the human and mouse β-globin locus-activating regions
-
Moon, A., and T. J. Ley. 1990. Conservation of the primary structure, organization, and function of the human and mouse β-globin locus-activating regions. Proc. Natl. Acad. Sci. USA 87:7693-7697.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7693-7697
-
-
Moon, A.1
Ley, T.J.2
-
27
-
-
0025779046
-
Functional properties of the β-globin locus control region in K562 erythroleukemia cells
-
Moon, A., and T. J. Ley. 1991. Functional properties of the β-globin locus control region in K562 erythroleukemia cells. Blood 77:2272-2284.
-
(1991)
Blood
, vol.77
, pp. 2272-2284
-
-
Moon, A.1
Ley, T.J.2
-
28
-
-
0027261194
-
Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human β-globin locus display proper developmental control of human globin genes
-
Peterson, K., C. Clegg, C. Huxley, B. Josephson, H. Haugen, T. Furukawa, and G. Stamatoyannopoulos. 1993. Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human β-globin locus display proper developmental control of human globin genes. Proc. Natl. Acad. Sci. USA 90:7593-7597.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7593-7597
-
-
Peterson, K.1
Clegg, C.2
Huxley, C.3
Josephson, B.4
Haugen, H.5
Furukawa, T.6
Stamatoyannopoulos, G.7
-
29
-
-
85085266538
-
Use of β-YAC mice for studying LCR function: Effect of 5′ HS-2 or HS-3 deletions on globin gene expression during development
-
Peterson, K. K., P. A. Navas, C. H. Clegg, and G. Stamatoyannopoulos. 1995. Use of β-YAC mice for studying LCR function: effect of 5′ HS-2 or HS-3 deletions on globin gene expression during development. Blood 86:586a.
-
(1995)
Blood
, vol.86
-
-
Peterson, K.K.1
Navas, P.A.2
Clegg, C.H.3
Stamatoyannopoulos, G.4
-
30
-
-
0027522759
-
The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the β globin locus control region
-
Philipsen, S., S. Pruzina, and F. Grosveld. 1993. The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the β globin locus control region. EMBO J. 12:1077-1085.
-
(1993)
EMBO J.
, vol.12
, pp. 1077-1085
-
-
Philipsen, S.1
Pruzina, S.2
Grosveld, F.3
-
31
-
-
0025292742
-
The β-globin dominant control region: Hypersensitive site 2
-
Philipsen, S., D. Talbot, P. Fraser, and F. Grosveld. 1990. The β-globin dominant control region: hypersensitive site 2. EMBO J. 9:2159-2167.
-
(1990)
EMBO J.
, vol.9
, pp. 2159-2167
-
-
Philipsen, S.1
Talbot, D.2
Fraser, P.3
Grosveld, F.4
-
32
-
-
0024494343
-
Nucleotide sequence of the BALB/c mouse β-globin complex
-
Shehee, W., D. Loeb, N. Adey, F. Burton, N. Casavant, P. Cole, C. Davies, R. McGraw, S. Schichman, D. Severynse, C. Voliva, F. Weyter, G. Wisely, M. Edgell, and C. Hutchison III. 1989. Nucleotide sequence of the BALB/c mouse β-globin complex. J. Mol. Biol. 205:41-62.
-
(1989)
J. Mol. Biol.
, vol.205
, pp. 41-62
-
-
Shehee, W.1
Loeb, D.2
Adey, N.3
Burton, F.4
Casavant, N.5
Cole, P.6
Davies, C.7
McGraw, R.8
Schichman, S.9
Severynse, D.10
Voliva, C.11
Weyter, F.12
Wisely, G.13
Edgell, M.14
Hutchison III, C.15
-
33
-
-
0026023289
-
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
-
Soriano, P., C. Montgomery, R. Geske, and A. Bradley. 1991. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64:639-702.
-
(1991)
Cell
, vol.64
, pp. 639-702
-
-
Soriano, P.1
Montgomery, C.2
Geske, R.3
Bradley, A.4
-
34
-
-
0002398438
-
Hemoglobin switching
-
G. Stamatoyannopoulos and A. W. Nienhuis (ed.), W. B. Saunders, Philadelphia
-
Stamatoyannopoulos, G., A. W. Nienhuis, P. Leder, P. W. Majerus (ed.). 1994. Hemoglobin switching, p. 107-155. In G. Stamatoyannopoulos and A. W. Nienhuis (ed.), The molecular basis of blood diseases. W. B. Saunders, Philadelphia.
-
(1994)
The Molecular Basis of Blood Diseases
, pp. 107-155
-
-
Stamatoyannopoulos, G.1
Nienhuis, A.W.2
Leder, P.3
Majerus, P.W.4
-
35
-
-
0028105984
-
Developmental regulation of human γ- And β-globin genes in the absence of the locus control region
-
Starck, J., R. Sarkar, M. Romana, A. Bhargava, A. Scarpa, M. Tanaka, J. Chamberlain, S. Weissman, and B. Forget. 1994. Developmental regulation of human γ- and β-globin genes in the absence of the locus control region. Blood 84:1656-1665.
-
(1994)
Blood
, vol.84
, pp. 1656-1665
-
-
Starck, J.1
Sarkar, R.2
Romana, M.3
Bhargava, A.4
Scarpa, A.5
Tanaka, M.6
Chamberlain, J.7
Weissman, S.8
Forget, B.9
-
36
-
-
0026655863
-
Developmental regulation of a complete 70-kb human β-globin locus in transgenic mice
-
Strouboulis, J., N. Dillon, and F. Grosveld. 1992 Developmental regulation of a complete 70-kb human β-globin locus in transgenic mice. Genes Dev. 6:1857-1864.
-
(1992)
Genes Dev.
, vol.6
, pp. 1857-1864
-
-
Strouboulis, J.1
Dillon, N.2
Grosveld, F.3
-
37
-
-
0024506821
-
A dominant control region from the human β-globin locus conferring integration site-independent gene expression
-
Talbot, D., P. Collis, M. Antoniou, M. Vidal, F. Grosveld, and D. Greaves. 1989. A dominant control region from the human β-globin locus conferring integration site-independent gene expression. Nature (London) 338:352-355.
-
(1989)
Nature (London)
, vol.338
, pp. 352-355
-
-
Talbot, D.1
Collis, P.2
Antoniou, M.3
Vidal, M.4
Grosveld, F.5
Greaves, D.6
-
38
-
-
0022100680
-
Erythroid-specific expression of human β-globin genes in transgenic mice
-
Townes, T., J. Lingrel, H. Chen, R. Brinster, R. Palmiter. 1985. Erythroid-specific expression of human β-globin genes in transgenic mice. EMBO J. 4:1715-1723.
-
(1985)
EMBO J.
, vol.4
, pp. 1715-1723
-
-
Townes, T.1
Lingrel, J.2
Chen, H.3
Brinster, R.4
Palmiter, R.5
-
39
-
-
0023440932
-
Upstream Gγ-globin and downstream β-globin sequences required for stage-specific expression in transgenic mice
-
Trudel, M., J. Magram, L. Bruckner, and F. Costantini. 1987. Upstream Gγ-globin and downstream β-globin sequences required for stage-specific expression in transgenic mice. Mol. Cell. Biol. 7:4024-4029.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 4024-4029
-
-
Trudel, M.1
Magram, J.2
Bruckner, L.3
Costantini, F.4
-
40
-
-
0344272073
-
The "β-like globin" gene domain in human erythroid cells
-
Tuan, D., W. Solomon, Q. Li, and I. London. 1985. The "β-like globin" gene domain in human erythroid cells. Proc. Natl. Acad. Sci. USA 82:6384-6388.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 6384-6388
-
-
Tuan, D.1
Solomon, W.2
Li, Q.3
London, I.4
-
41
-
-
0025055032
-
The function of normal and mutated γ-globin gene promoters in electroporated K562 erythroleukemia cells
-
Ulrich, M., and T. J. Ley. The function of normal and mutated γ-globin gene promoters in electroporated K562 erythroleukemia cells. 1990. Blood 75: 990-999.
-
(1990)
Blood
, vol.75
, pp. 990-999
-
-
Ulrich, M.1
Ley, T.J.2
-
42
-
-
0025241133
-
Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse
-
Whitelaw, E., S. Tsai, P. Hogben, and S. Orkin. 1990. Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse. Mol. Cell. Biol. 10:6596-6606.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 6596-6606
-
-
Whitelaw, E.1
Tsai, S.2
Hogben, P.3
Orkin, S.4
|