PPARγ ligands induce ER stress in pancreatic β-cells: ER stress activation results in attenuation of cytokine signaling

American Journal of Physiology - Endocrinology and Metabolism

Volumn 287, Issue 6 50-6, 2004, Pages

  Weber, Sarah M ^a   Chambers, Kari T ^a   Bensch, Kenneth G ^a   Scarim, Anna L ^a   Corbett, John A ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endoplasmic reticulum; Interferon ; Peroxisome proliferator activated receptor ; Unfolded protein response

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; CIGLITAZONE; CYTOKINE; GAMMA INTERFERON; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN 70; INITIATION FACTOR 2; INITIATION FACTOR 2ALPHA; INTERLEUKIN 1; NETOGLITAZONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN J2; ROSIGLITAZONE; TROGLITAZONE; UNCLASSIFIED DRUG; 15 DEOXY DELTA(12,14) PROSTAGLANDIN J2; 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J2; DRUG DERIVATIVE; LIGAND; PROSTAGLANDIN D2; PROTEIN;

ANIMAL CELL; ARTICLE; ATTENUATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOPLASMIC RETICULUM; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; RAT; SIGNAL TRANSDUCTION; STRESS; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PANCREAS ISLET; PATHOPHYSIOLOGY; PHOSPHORYLATION; PROTEIN FOLDING; SPRAGUE DAWLEY RAT;

ANIMALS; CYTOKINES; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION; ISLETS OF LANGERHANS; LIGANDS; PHOSPHORYLATION; PPAR GAMMA; PROSTAGLANDIN D2; PROTEIN FOLDING; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STRESS;

EID: 8544267219     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00331.2004     Document Type: Article

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