Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches

Journal of Mass Spectrometry

Volumn 43, Issue 8, 2008, Pages 1021-1036

  Konermann, Lars ^a   Tong, Xin ^a   Pan, Yan ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Electrospray ionization; Hydrogen bonds; Protein conformation; Protein folding; Radical scavenger; Solvent exposure; Structural dynamics

Indexed keywords

CHLORINE COMPOUNDS; CONCENTRATION (PROCESS); DOPING (ADDITIVES); DYNAMICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; IONIZATION OF GASES; IONIZATION OF LIQUIDS; ISOTOPES; LABELING; MASS SPECTROMETERS; MASS SPECTROMETRY; PROTEINS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; STOICHIOMETRY; VACUUM APPLICATIONS;

ANALYTES; BINDING PARTNERS; COMPUTATIONAL SIMULATIONS; DEGREE OF SOLUTION; ELECTROSPRAY IONIZATION (ESI); GAS-PHASE; GAS-PHASE IONS; H/D EXCHANGE; HYDROGEN BONDS; HYDROGEN/DEUTERIUM EXCHANGE; HYDROXYL RADICAL; IONIZATION PROCESSES; ISOTOPE EXCHANGE; NON-COVALENT COMPLEXES; PROTEIN CONCENTRATIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURES; RADICAL SCAVENGER; RADICAL SCAVENGERS; SIMPLE METHODS; SOLVENT EXPOSURE; STRUCTURAL DYNAMICS;

ELECTROSPRAY IONIZATION;

DEUTERIUM; HYDROXYL GROUP; ION; ISOTOPE; SCAVENGER;

CONCENTRATION (PARAMETERS); ELECTROSPRAY MASS SPECTROMETRY; GAS; IONIZATION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; PROTON TRANSPORT; REVIEW; SIMULATION; STOICHIOMETRY;

ANIMALS; DEUTERIUM EXCHANGE MEASUREMENT; HUMANS; HYDROXYL RADICAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPIN LABELS;

EID: 49549086897     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1435     Document Type: Review

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