Intramolecular migration of amide hydrogens in protonated peptides upon collisional activation

Journal of the American Chemical Society

Volumn 127, Issue 8, 2005, Pages 2785-2793

  Jørgensen, Thomas J D ^a,b   Gårdsvoll, Henrik ^b   Ploug, Michael ^b   Roepstorff, Peter ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b FINSEN LABORATORY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; COMPLEXATION; HYDROGEN; ION EXCHANGE; MASS SPECTROMETRY; MOLECULAR STRUCTURE; POLYPEPTIDES;

AMIDE HYDROGENS; COLLISIONAL ACTIVATION; HYDROGEN MIGRATION; NONBINDING SEQUENCES;

POLYAMIDES;

AMIDE; DEUTERIUM; HYDROGEN; PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DISSOCIATION; ELECTRON TRANSPORT; GAS; MASS SPECTROMETRY; MODEL; MOLECULAR INTERACTION; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTON TRANSPORT; RECEPTOR BINDING; SEQUENCE ANALYSIS; TIME OF FLIGHT MASS SPECTROMETRY;

AMIDES; DEUTERIUM EXCHANGE MEASUREMENT; HYDROGEN; MASS SPECTROMETRY; PEPTIDES; RECEPTORS, CELL SURFACE;

EID: 14744272834     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja043789c     Document Type: Article

References (59)

1. Yan, X. G.; Watson, J.; Ho, P. S.; Deinzer, M. L. Mol. Cell. Proteomics 2004, 3, 10-23.
2. Konermann, L.; Simmons, D. A. Mass Spectrom. Rev. 2003, 22, 1-26.
3. (a) Hoofnagle, A. N.; Resing, K. A.; Ahn, N. G. Annu. Rev. Biophys. Biomol. Struct. 2003, 32, 1-25.
4. (b) Engen, J. R.; Smith, D. L. Methods Mol. Biol. 2000, 146, 95-112.
5. Wang, Y.; Gross, M. L. In Applied Electrospray Mass Spectrometry; Ganguly, A. K., Pramanik, B. N., Gross, M. L., Eds.; Marcel Dekker: New York, 2002; pp 389-410.
6. An exchange reaction is correlated if a number of otherwise protected amide hydrogens become transiently simultaneously solvated and thereby undergoes exchange. For example, a cooperative unfolding of a protein may lead to correlated exchange if the lifetime of the unfolded state is sufficiently long to allow exchange of several amide hydrogens.
7. Canet, D.; Last, A. M.; Tito, P.; Sunde, M.; Spencer, A.; Archer, D. B.; Redfield, C.; Robinson, C. V.; Dobson, C. M. Nat. Struct. Biol. 2002, 9, 308-315.
8. Engen, J. R.; Smithgall, T. E.; Gmeiner, W. H.; Smith, D. L. Biochemistry 1997, 36, 14384-14391.
9. Arrington, C. B.; Teesch, L. M.; Robertson, A. D. J. Mol. Biol. 1999, 285, 1265-1275.
10. Heegaard, N. H. H.; Jørgensen, T. J. D.; Rozlosnik, N.; Corlin, D. B.; Pedersen, J. S.; Tempesta, A. G.; Roepstorff, P.; Bauer, R.; Nissen, M. H. Biochemistry, in press.
11. Miranker, A.; Robinson, C. V.; Radford, S. E.; Aplin, R. T.; Dobson, C. M. Science 1993, 262, 896-900.
12. Jørgensen, T. J. D.; Gårdsvoll, H.; Danø, K.; Roepstorff, P.; Ploug, M. Biochemistry 2004, 43, 15044-15057.
13. Zhang, Z.; Smith, D. L. Protein Sci. 1993, 2, 522-531.
14. Deng, Y. Z.; Pan, H.; Smith, D. L. J. Am. Chem. Soc. 1999, 121, 1966-1967.
15. Kim, M. Y.; Maier, C. S.; Reed, D. J.; Deinzer, M. L. J. Am. Chem. Soc. 2001, 123, 9860-9866.
16. Kim, M. Y.; Maier, C. S.; Reed, D. J.; Ho, P. S.; Deinzer, M. L. Biochemistry 2001, 40, 14413-14421.
17. Akashi, S.; Naito, Y.; Takio, K. Anal. Chem. 1999, 71, 4974-4980.
18. Waring, A. J.; Mobley, P. W.; Gordon, L. M. Proteins 1998, 38-49.
19. Eyles, S. J.; Speir, J. P.; Kruppa, G. H.; Gierasch, L. M.; Kaltashov, I. A. J. Am. Chem. Soc. 2000, 122, 495-500.
20. Hoerner, J. K.; Xiao, H.; Dobo, A.; Kaltashov, I. A. J. Am. Chem. Soc. 2004, 126, 7709-7717.
21. Demmers, J. A. A.; Rijkers, D. T. S.; Haverkamp, J.; Killian, J. A.; Heck, A. J. R. J. Am. Chem. Soc. 2002, 124, 11191-11198.
22. Johnson, R. S.; Krylov, D.; Walsh, K. A. J. Mass Spectrom. 1995, 30, 386-387.
23. Harrison, A. G.; Yalcin, T. Int. J. Mass Spectrom. 1997, 165, 339-347.
24. Mueller, D. R.; Eckersley, M.; Richter, W. J. Org. Mass Spectrom. 1988, 23, 217-222.
25. McLafferty, F. W.; Guan, Z. Q.; Haupts, U.; Wood, T. D.; Kelleher, N. L. J. Am. Chem. Soc. 1998, 120, 4732-4740.
26. Ploug, M.; Østergaard, S.; Gårdsvoll, H.; Kovalski, K.; Holst-Hansen, C.; Holm, A.; Ossowski, L.; Danø, K. Biochemistry 2001, 40, 12157-12168.
27. Ploug, M.; Østergaard, S.; Hansen, L. B.; Holm, A.; Danø, K. Biochemistry 1998, 37, 3612-3622.
28. Ploug, M.; Kjalke, M.; Rønne, E.; Weidle, U.; Høyer-Hansen, G.; Danø, K. J. Biol. Chem. 1993, 268, 17539-17546.
29. Bai, Y.; Milne, J. S.; Mayne, L.; Englander, S. W. 1993, 17, 75-86.
30. Zhang, Z. Q.; Guan, S. H.; Marshall, A. G. J. Am. Soc. Mass Spectrom. 1997, 8, 659-670.
31. Ploug, M. Curr. Pharm. Des. 2003, 9, 639-652.
32. The effect of the C-terminal COOH group on the amide hydrogen exchange rate in Cha was investigated by mimicking Cha with either Phe or Ile. For both residues, the effect was negligible.
33. (a) Dongre, A. R.; Jones, J. L.; Somogyi, A.; Wysocki, V. H. J. Am. Chem. Soc. 1996, 118, 8365-8374.
34. (b) Tsaprailis, G.; Nair, H.; Somogyi, A.; Wysocki, V. H.; Zhong, W. Q.; Futrell, J. H.; Summerfield, S. G.; Gaskell, S. J. J. Am. Chem. Soc. 1999, 121, 5142-5154.
35. Tabb, D. L.; Huang, Y. Y.; Wysocki, V. H.; Yates, J. R. Anal. Chem. 2004, 76, 1243-1248.
36. Yan, X. G.; Zhang, H. D.; Watson, J.; Schimerlik, M. I.; Deinzer, M. L. Protein Sci. 2002, 11, 2113-2124.
37. Akashi, S.; Takio, K. J. Am. Soc. Mass Spectrom. 2001, 12, 1247-1253.
38. Anderegg, R. J.; Wagner, D. S.; Stevenson, C. L.; Borchardt, R. T. J. Am. Soc. Mass Spectrom. 1994, 5, 425-433.
39. Akashi, S.; Takio, K. Protein Sci. 2000, 9, 2497-2505.
40. Buijs, J.; Hakansson, K.; Hagman, C.; Hakansson, P.; Oscarsson, S. Rapid Commun. Mass Spectrom. 2000, 14, 1751-1756.
41. Kraus, M.; Janek, K.; Bienert, M.; Krause, E. Rapid Commun. Mass Spectrom. 2000, 14, 1094-1104.
42. Yamada, N.; Suzuki, E.; Hirayama, K. Rapid Commun. Mass Spectrom. 2002, 16, 293-299.
43. Kraus, M.; Bienert, M.; Krause, E. Rapid Commun. Mass Spectrom. 2003, 17, 222-228.
44. McLuckey, S. A.; Goeringer, D. E. J. Mass Spectrom. 1997, 32, 461-474.
45. Vachet, R. W.; Bishop, B. M.; Erickson, B. W.; Glish, G. L. J. Am. Chem. Soc. 1997, 119, 5481-5488.
46. Yague, J.; Paradela, A.; Ramos, M.; Ogueta, S.; Marina, A.; Barahona, F.; de Castro, J. A. L.; Vazquez, J. Anal. Chem. 2003, 75, 1524-1535.
47. Kaltashov, I. A.; Eyles, S. J. J. Mass Spectrom. 2002, 37, 557-565.
48. Harrison, A. G. Rapid Commun. Mass Spectrom. 1999, 13, 1663-1670.
49. Hagman, C.; Hakansson, P.; Buijs, J.; Hakansson, K. J. Am. Soc. Mass Spectrom. 2004, 15, 639-646.
50. Wysocki, V. H.; Tsaprailis, G.; Smith, L. L.; Breci, L. A. J. Mass Spectrom. 2000, 35, 1399-1406.
51. Yalcin, T.; Khouw, C.; Csizmadia, I. G.; Peterson, M. R.; Harrison, A. G. J. Am. Soc. Mass Spectrom. 1995, 6, 1165-1174.
52. Yalcin, T.; Csizmadia, I. G.; Peterson, M. R.; Harrison, A. G. J. Am. Soc. Mass Spectrom. 1996, 7, 233-242.
53. Klassen, J. S.; Kebarle, P. J. Am. Chem. Soc. 1997, 119, 6552-6563.
54. Cordero, M. M.; Houser, J. J.; Wesdemiotis, C. Anal. Chem. 1993, 65, 1594-1601.
55. Cordero, M. M.; Wesdemiotis, C. Org. Mass Spectrom. 1994, 29, 382-390.
56. Csonka, I. P.; Paizs, B.; Lendvay, G.; Suhai, S. Rapid Commun. Mass Spectrom. 2000, 14, 417-431.
57. Csonka, I. P.; Paizs, B.; Lendvay, G.; Suhai, S. Rapid Commun. Mass Spectrom. 2001, 15, 1457-1472.
58. Paizs, B.; Csonka, I. P.; Lendvay, G.; Suhai, S. Rapid Commun. Mass Spectrom. 2001, 15, 637-650.
59. Rodriquez, C. F.; Cunje, A.; Shoeib, T.; Chu, I. K.; Hopkinson, A. C.; Siu, K. W. M. J. Am. Chem. Soc. 2001, 123, 3006-3012.