Mapping protein energy landscapes with amide hydrogen exchange and mass spectrometry: I. A generalized model for a two-state protein and comparison with experiment

Protein Science

Volumn 14, Issue 2, 2005, Pages 543-557

  Xiao, Hui ^a   Hoerner, Joshua K ^a   Eyles, Stephen J ^a   Dobo, Andras ^a   Voigtman, Edward ^a   Mel'Čuk, Andre I ^a   Kaltashov, Igor A ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Amide hydrogen exchange; Mass spectrometry; Protein dynamics; Protein energy landscape; Protein equilibrium states

Indexed keywords

AMIDE; CHYMOTRYPSIN INHIBITOR; HYDROGEN; SOLVENT;

ALGORITHM; AMIDE HYDROGEN EXCHANGE; ARTICLE; CHEMICAL ANALYSIS; ENERGY TRANSFER; EQUILIBRIUM CONSTANT; EXPERIMENT; IONIZATION; ISOTOPE LABELING; KINETICS; MASS SPECTROMETRY; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN ENERGY LANDSCAPE;

ALGORITHMS; HORDEUM; HYDROGEN; IONS; KINETICS; MASS SPECTROMETRY; MODELS, CHEMICAL; MODELS, STATISTICAL; MODELS, THEORETICAL; PEPTIDES; PLANT PROTEINS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEINS; PROTEOMICS; TEMPERATURE; TIME FACTORS;

EID: 13244258262     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.041001705     Document Type: Article

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