Intrinsic dynamics of an enzyme underlies catalysis

Nature

Volumn 438, Issue 7064, 2005, Pages 117-121

  Eisenmesser, Elan Z ^a   Millet, Oscar ^b,d   Labeikovsky, Wladimir ^a   Korzhnev, Dmitry M ^b   Wolf Watz, Magnus ^a,g   Bosco, Daryl A ^a,e   Skalicky, Jack J ^c,f   Kay, Lewis E ^b   Kern, Dorothee ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c FLORIDA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF BARCELONA   (Spain)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^g UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCATALYSTS; CATALYSIS; CHARACTERIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRESSURE EFFECTS;

INTRINSIC PROPERTY; MUTANTS; STATIC THREE-DIMENSIONAL STRUCTURES;

ENZYMES;

CYCLOPHILIN A; MUTANT PROTEIN;

BIOLOGY;

ARTICLE; BIOCATALYST; CATALYSIS; CORRELATION ANALYSIS; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; MOLECULAR EVOLUTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

EID: 27744499156     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04105     Document Type: Article

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