Kinetic unfolding mechanism of the inducible nitric oxide synthase oxygenase domain determined by time-resolved electrospray mass spectrometry

Biochemistry

Volumn 44, Issue 7, 2005, Pages 2276-2283

  Wilson, Derek J ^a   Rafferty, Steven P ^b   Konermann, Lars ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b TRENT UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; COMPLEXATION; MASS SPECTROMETRY; MONOMERS; NITROGEN COMPOUNDS; PH EFFECTS; PROTEINS; RELAXATION PROCESSES;

DENATURATION; HOLO MONOMERS; ON-LINE RAPID MIXING; TIME-RESOLVED ELECTROSPRAY MASS SPECTROMETRY;

ENZYME KINETICS;

APOPROTEIN; DIMER; HEME DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; OXYGENASE; TETRAHYDROBIOPTERIN;

ARTICLE; CHEMICAL REACTION KINETICS; DENATURATION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME MECHANISM; LIGAND BINDING; PH; PRIORITY JOURNAL; PROTEIN FOLDING; REACTION ANALYSIS;

ANIMALS; DIMERIZATION; HEME OXYGENASE (DECYCLIZING); HYDROGEN-ION CONCENTRATION; KINETICS; MICE; MODELS, CHEMICAL; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXYGENASES; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS;

EID: 14044268842     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047684y     Document Type: Article

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