-
1
-
-
33645307434
-
Pathogenetic mechanisms in thyroid follicular-cell neoplasia
-
Kondo T., Ezzat S., and Asa S.L. Pathogenetic mechanisms in thyroid follicular-cell neoplasia. Nat Rev Cancer 6 4 (2006) 292-306
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.4
, pp. 292-306
-
-
Kondo, T.1
Ezzat, S.2
Asa, S.L.3
-
2
-
-
0028217602
-
Role of the cyclic adenosine 3′,5′-monophosphate and the phosphatidylinositol-Ca2+ cascades in mediating the effects of thyrotropin and iodide on hormone synthesis and secretion in human thyroid slices
-
Corvilain B., Laurent E., Lecomte M., et al. Role of the cyclic adenosine 3′,5′-monophosphate and the phosphatidylinositol-Ca2+ cascades in mediating the effects of thyrotropin and iodide on hormone synthesis and secretion in human thyroid slices. J Clin Endocrinol Metab 79 1 (1994) 152-159
-
(1994)
J Clin Endocrinol Metab
, vol.79
, Issue.1
, pp. 152-159
-
-
Corvilain, B.1
Laurent, E.2
Lecomte, M.3
-
3
-
-
0024614795
-
The cyclic AMP-mediated stimulation of cell proliferation
-
Dumont J.E., Jauniaux J.C., and Roger P.P. The cyclic AMP-mediated stimulation of cell proliferation. Trends Biochem Sci 14 2 (1989) 67-71
-
(1989)
Trends Biochem Sci
, vol.14
, Issue.2
, pp. 67-71
-
-
Dumont, J.E.1
Jauniaux, J.C.2
Roger, P.P.3
-
4
-
-
0024404145
-
GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours
-
Landis C.A., Masters S.B., Spada A., et al. GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 340 6236 (1989) 692-696
-
(1989)
Nature
, vol.340
, Issue.6236
, pp. 692-696
-
-
Landis, C.A.1
Masters, S.B.2
Spada, A.3
-
5
-
-
0025127424
-
Two G protein oncogenes in human endocrine tumors
-
Lyons J., Landis C.A., Harsh G., et al. Two G protein oncogenes in human endocrine tumors. Science 249 4969 (1990) 655-659
-
(1990)
Science
, vol.249
, Issue.4969
, pp. 655-659
-
-
Lyons, J.1
Landis, C.A.2
Harsh, G.3
-
6
-
-
0025865247
-
Gsp mutations in human thyroid tumours
-
Suarez H.G., du Villard J.A., Caillou B., et al. Gsp mutations in human thyroid tumours. Oncogene 6 4 (1991) 677-679
-
(1991)
Oncogene
, vol.6
, Issue.4
, pp. 677-679
-
-
Suarez, H.G.1
du Villard, J.A.2
Caillou, B.3
-
7
-
-
0026009016
-
Activating point mutations of the gsp oncogene in human thyroid adenomas
-
O'Sullivan C., Barton C.M., Staddon S.L., et al. Activating point mutations of the gsp oncogene in human thyroid adenomas. Mol Carcinog 4 5 (1991) 345-349
-
(1991)
Mol Carcinog
, vol.4
, Issue.5
, pp. 345-349
-
-
O'Sullivan, C.1
Barton, C.M.2
Staddon, S.L.3
-
8
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
Parma J., Duprez L., Van Sande J., et al. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature 365 6447 (1993) 649-651
-
(1993)
Nature
, vol.365
, Issue.6447
, pp. 649-651
-
-
Parma, J.1
Duprez, L.2
Van Sande, J.3
-
9
-
-
0029044073
-
Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3′,5′-monophosphate and inositol phosphate-Ca2+ cascades
-
Parma J., Van Sande J., Swillens S., et al. Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3′,5′-monophosphate and inositol phosphate-Ca2+ cascades. Mol Endocrinol 9 6 (1995) 725-733
-
(1995)
Mol Endocrinol
, vol.9
, Issue.6
, pp. 725-733
-
-
Parma, J.1
Van Sande, J.2
Swillens, S.3
-
10
-
-
0036353475
-
Somatic mutations in thyroid nodular disease
-
Krohn K., and Paschke R. Somatic mutations in thyroid nodular disease. Mol Genet Metab 75 3 (2002) 202-208
-
(2002)
Mol Genet Metab
, vol.75
, Issue.3
, pp. 202-208
-
-
Krohn, K.1
Paschke, R.2
-
11
-
-
0034463802
-
Detection of thyroid-stimulating hormone receptor and Gsalpha mutations: in 75 toxic thyroid nodules by denaturing gradient gel electrophoresis
-
Trulzsch B., Krohn K., Wonerow P., et al. Detection of thyroid-stimulating hormone receptor and Gsalpha mutations: in 75 toxic thyroid nodules by denaturing gradient gel electrophoresis. J Mol Med 78 12 (2001) 684-691
-
(2001)
J Mol Med
, vol.78
, Issue.12
, pp. 684-691
-
-
Trulzsch, B.1
Krohn, K.2
Wonerow, P.3
-
12
-
-
0031738399
-
Clonal origin of toxic thyroid nodules with constitutively activating thyrotropin receptor mutations
-
Krohn K., Führer D., Holzapfel H.P., et al. Clonal origin of toxic thyroid nodules with constitutively activating thyrotropin receptor mutations. J Clin Endocrinol Metab 83 1 (1998) 130-134
-
(1998)
J Clin Endocrinol Metab
, vol.83
, Issue.1
, pp. 130-134
-
-
Krohn, K.1
Führer, D.2
Holzapfel, H.P.3
-
13
-
-
0033306856
-
Functioning and nonfunctioning thyroid adenomas involve different molecular pathogenetic mechanisms
-
Tonacchera M., Vitti P., Agretti P., et al. Functioning and nonfunctioning thyroid adenomas involve different molecular pathogenetic mechanisms. J Clin Endocrinol Metab 84 11 (1999) 4155-4158
-
(1999)
J Clin Endocrinol Metab
, vol.84
, Issue.11
, pp. 4155-4158
-
-
Tonacchera, M.1
Vitti, P.2
Agretti, P.3
-
14
-
-
0028316849
-
Molecular basis of thyroid cancer
-
Farid N.R., Shi Y., and Zou M. Molecular basis of thyroid cancer. Endocr Rev 15 2 (1994) 202-232
-
(1994)
Endocr Rev
, vol.15
, Issue.2
, pp. 202-232
-
-
Farid, N.R.1
Shi, Y.2
Zou, M.3
-
15
-
-
0028671806
-
Oncogenes and anti-oncogenes in human epithelial thyroid tumors
-
Said S., Schlumberger M., and Suarez H.G. Oncogenes and anti-oncogenes in human epithelial thyroid tumors. J Endocrinol Invest 17 5 (1994) 371-379
-
(1994)
J Endocrinol Invest
, vol.17
, Issue.5
, pp. 371-379
-
-
Said, S.1
Schlumberger, M.2
Suarez, H.G.3
-
16
-
-
0034980681
-
Mutation analysis of the Epac-Rap1 signaling pathway in cold thyroid follicular adenomas
-
Vanvooren V., Allgeier A., Nguyen M., et al. Mutation analysis of the Epac-Rap1 signaling pathway in cold thyroid follicular adenomas. Eur J Endocrinol 144 6 (2001) 605-610
-
(2001)
Eur J Endocrinol
, vol.144
, Issue.6
, pp. 605-610
-
-
Vanvooren, V.1
Allgeier, A.2
Nguyen, M.3
-
17
-
-
30344476973
-
PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma
-
Castro P., Rebocho A.P., Soares R.J., et al. PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma. J Clin Endocrinol Metab 91 1 (2006) 213-220
-
(2006)
J Clin Endocrinol Metab
, vol.91
, Issue.1
, pp. 213-220
-
-
Castro, P.1
Rebocho, A.P.2
Soares, R.J.3
-
18
-
-
0033984548
-
Role of Ras mutation in the progression of thyroid carcinoma of follicular epithelial origin
-
Motoi N., Sakamoto A., Yamochi T., et al. Role of Ras mutation in the progression of thyroid carcinoma of follicular epithelial origin. Pathol Res Pract 196 1 (2000) 1-7
-
(2000)
Pathol Res Pract
, vol.196
, Issue.1
, pp. 1-7
-
-
Motoi, N.1
Sakamoto, A.2
Yamochi, T.3
-
20
-
-
0032935093
-
Genetic analysis of the TSH receptor gene in differentiated human thyroid carcinomas
-
Cetani F., Tonacchera M., Pinchera A., et al. Genetic analysis of the TSH receptor gene in differentiated human thyroid carcinomas. J Endocrinol Invest 22 4 (1999) 273-278
-
(1999)
J Endocrinol Invest
, vol.22
, Issue.4
, pp. 273-278
-
-
Cetani, F.1
Tonacchera, M.2
Pinchera, A.3
-
21
-
-
0029799977
-
Structural studies of the thyrotropin receptor and Gs alpha in human thyroid cancers: low prevalence of mutations predicts infrequent involvement in malignant transformation
-
Spambalg D., Sharifi N., Elisei R., et al. Structural studies of the thyrotropin receptor and Gs alpha in human thyroid cancers: low prevalence of mutations predicts infrequent involvement in malignant transformation. J Clin Endocrinol Metab 81 11 (1996) 3898-3901
-
(1996)
J Clin Endocrinol Metab
, vol.81
, Issue.11
, pp. 3898-3901
-
-
Spambalg, D.1
Sharifi, N.2
Elisei, R.3
-
22
-
-
0031764971
-
Absence of activating mutations of the genes encoding the alpha-subunits of G11 and Gq in thyroid neoplasia
-
Ringel M.D., Saji M., Schwindinger W.F., et al. Absence of activating mutations of the genes encoding the alpha-subunits of G11 and Gq in thyroid neoplasia. J Clin Endocrinol Metab 83 2 (1998) 554-559
-
(1998)
J Clin Endocrinol Metab
, vol.83
, Issue.2
, pp. 554-559
-
-
Ringel, M.D.1
Saji, M.2
Schwindinger, W.F.3
-
23
-
-
33745223872
-
Follicular carcinoma presenting as autonomous functioning thyroid nodule and containing an activating mutation of the TSH receptor (T620I) and a mutation of the Ki-RAS (G12C) genes
-
Niepomniszcze H., Suarez H., Pitoia F., et al. Follicular carcinoma presenting as autonomous functioning thyroid nodule and containing an activating mutation of the TSH receptor (T620I) and a mutation of the Ki-RAS (G12C) genes. Thyroid 16 5 (2006) 497-503
-
(2006)
Thyroid
, vol.16
, Issue.5
, pp. 497-503
-
-
Niepomniszcze, H.1
Suarez, H.2
Pitoia, F.3
-
24
-
-
0029838821
-
Clinical Review 84: Thyroid autonomy: mechanism and clinical effects
-
Dremier S., Coppee F., Delange F., et al. Clinical Review 84: Thyroid autonomy: mechanism and clinical effects. J Clin Endocrinol Metab 81 12 (1996) 4187-4193
-
(1996)
J Clin Endocrinol Metab
, vol.81
, Issue.12
, pp. 4187-4193
-
-
Dremier, S.1
Coppee, F.2
Delange, F.3
-
25
-
-
10044235331
-
Does a Leu 512 Arg thyrotropin receptor mutation cause an autonomously functioning papillary carcinoma?
-
Gozu H., Avsar M., Bircan R., et al. Does a Leu 512 Arg thyrotropin receptor mutation cause an autonomously functioning papillary carcinoma?. Thyroid 14 11 (2004) 975-980
-
(2004)
Thyroid
, vol.14
, Issue.11
, pp. 975-980
-
-
Gozu, H.1
Avsar, M.2
Bircan, R.3
-
26
-
-
0034487437
-
A Phe 486 thyrotropin receptor mutation in an autonomously functioning follicular carcinoma that was causing hyperthyroidism
-
Camacho P., Gordon D., Chiefari E., et al. A Phe 486 thyrotropin receptor mutation in an autonomously functioning follicular carcinoma that was causing hyperthyroidism. Thyroid 10 11 (2000) 1009-1012
-
(2000)
Thyroid
, vol.10
, Issue.11
, pp. 1009-1012
-
-
Camacho, P.1
Gordon, D.2
Chiefari, E.3
-
27
-
-
0033025188
-
A Val 677 activating mutation of the thyrotropin receptor in a Hürthle cell thyroid carcinoma associated with thyrotoxicosis
-
Russo D., Wong M.G., Costante G., et al. A Val 677 activating mutation of the thyrotropin receptor in a Hürthle cell thyroid carcinoma associated with thyrotoxicosis. Thyroid 9 1 (1999) 13-17
-
(1999)
Thyroid
, vol.9
, Issue.1
, pp. 13-17
-
-
Russo, D.1
Wong, M.G.2
Costante, G.3
-
28
-
-
0024376173
-
Ras oncogenes in human cancer: a review
-
Bos J.L. Ras oncogenes in human cancer: a review. Cancer Res 49 17 (1989) 4682-4689
-
(1989)
Cancer Res
, vol.49
, Issue.17
, pp. 4682-4689
-
-
Bos, J.L.1
-
29
-
-
0034762203
-
The Raf/MEK/ERK pathway: new concepts of activation
-
Peyssonnaux C., and Eychene A. The Raf/MEK/ERK pathway: new concepts of activation. Biol Cell 93 1-2 (2001) 53-62
-
(2001)
Biol Cell
, vol.93
, Issue.1-2
, pp. 53-62
-
-
Peyssonnaux, C.1
Eychene, A.2
-
30
-
-
0037564807
-
Specific pattern of RAS oncogene mutations in follicular thyroid tumors
-
Vasko V., Ferrand M., Di Cristofaro J., et al. Specific pattern of RAS oncogene mutations in follicular thyroid tumors. J Clin Endocrinol Metab 88 6 (2003) 2745-2752
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.6
, pp. 2745-2752
-
-
Vasko, V.1
Ferrand, M.2
Di Cristofaro, J.3
-
31
-
-
0030693895
-
Oncogenes and antioncogenes involved in human thyroid carcinogenesis
-
Lazzereschi D., Mincione G., Coppa A., et al. Oncogenes and antioncogenes involved in human thyroid carcinogenesis. J Exp Clin Cancer Res 16 3 (1997) 325-332
-
(1997)
J Exp Clin Cancer Res
, vol.16
, Issue.3
, pp. 325-332
-
-
Lazzereschi, D.1
Mincione, G.2
Coppa, A.3
-
32
-
-
0032940645
-
Oncogene profile of papillary thyroid carcinoma
-
Sugg S.L., Ezzat S., Zheng L., et al. Oncogene profile of papillary thyroid carcinoma. Surgery 125 1 (1999) 46-52
-
(1999)
Surgery
, vol.125
, Issue.1
, pp. 46-52
-
-
Sugg, S.L.1
Ezzat, S.2
Zheng, L.3
-
33
-
-
0012683188
-
RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma
-
Nikiforova M.N., Lynch R.A., Biddinger P.W., et al. RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma. J Clin Endocrinol Metab 88 5 (2003) 2318-2326
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.5
, pp. 2318-2326
-
-
Nikiforova, M.N.1
Lynch, R.A.2
Biddinger, P.W.3
-
34
-
-
85047687680
-
Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations
-
Zhu Z., Gandhi M., Nikiforova M.N., et al. Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations. Am J Clin Pathol 120 1 (2003) 71-77
-
(2003)
Am J Clin Pathol
, vol.120
, Issue.1
, pp. 71-77
-
-
Zhu, Z.1
Gandhi, M.2
Nikiforova, M.N.3
-
35
-
-
33745135726
-
Molecular genetic study comparing follicular variant versus classic papillary thyroid carcinomas: association of N-ras mutation in codon 61 with follicular variant
-
Di Cristofaro J., Marcy M., Vasko V., et al. Molecular genetic study comparing follicular variant versus classic papillary thyroid carcinomas: association of N-ras mutation in codon 61 with follicular variant. Hum Pathol 37 7 (2006) 824-830
-
(2006)
Hum Pathol
, vol.37
, Issue.7
, pp. 824-830
-
-
Di Cristofaro, J.1
Marcy, M.2
Vasko, V.3
-
36
-
-
33645232222
-
Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas
-
Adeniran A.J., Zhu Z., Gandhi M., et al. Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas. Am J Surg Pathol 30 2 (2006) 216-222
-
(2006)
Am J Surg Pathol
, vol.30
, Issue.2
, pp. 216-222
-
-
Adeniran, A.J.1
Zhu, Z.2
Gandhi, M.3
-
37
-
-
21444459537
-
Chromosomal instability, aneuploidy, and gene mutations in human sporadic colorectal adenomas
-
Giaretti W., Molinu S., Ceccarelli J., et al. Chromosomal instability, aneuploidy, and gene mutations in human sporadic colorectal adenomas. Cell Oncol 26 5-6 (2004) 301-305
-
(2004)
Cell Oncol
, vol.26
, Issue.5-6
, pp. 301-305
-
-
Giaretti, W.1
Molinu, S.2
Ceccarelli, J.3
-
38
-
-
0028946895
-
K-ras-2 G-C and G-T transversions correlate with DNA aneuploidy in colorectal adenomas
-
Giaretti W., Pujic N., Rapallo A., et al. K-ras-2 G-C and G-T transversions correlate with DNA aneuploidy in colorectal adenomas. Gastroenterology 108 4 (1995) 1040-1047
-
(1995)
Gastroenterology
, vol.108
, Issue.4
, pp. 1040-1047
-
-
Giaretti, W.1
Pujic, N.2
Rapallo, A.3
-
39
-
-
0031715339
-
Specific K-ras2 mutations in human sporadic colorectal adenomas are associated with DNA near-diploid aneuploidy and inhibition of proliferation
-
Giaretti W., Rapallo A., Geido E., et al. Specific K-ras2 mutations in human sporadic colorectal adenomas are associated with DNA near-diploid aneuploidy and inhibition of proliferation. Am J Pathol 153 4 (1998) 1201-1209
-
(1998)
Am J Pathol
, vol.153
, Issue.4
, pp. 1201-1209
-
-
Giaretti, W.1
Rapallo, A.2
Geido, E.3
-
40
-
-
0036256349
-
Minireview: Branded from the start-distinct oncogenic initiating events may determine tumor fate in the thyroid
-
Fagin J.A. Minireview: Branded from the start-distinct oncogenic initiating events may determine tumor fate in the thyroid. Mol Endocrinol 16 5 (2002) 903-911
-
(2002)
Mol Endocrinol
, vol.16
, Issue.5
, pp. 903-911
-
-
Fagin, J.A.1
-
41
-
-
0020031840
-
The diagnostic value of flow cytometric DNA measurements in selected disorders of the human thyroid
-
Johannessen J.V., Sobrinho-Simões M., Lindmo T., et al. The diagnostic value of flow cytometric DNA measurements in selected disorders of the human thyroid. Am J Clin Pathol 77 1 (1982) 20-25
-
(1982)
Am J Clin Pathol
, vol.77
, Issue.1
, pp. 20-25
-
-
Johannessen, J.V.1
Sobrinho-Simões, M.2
Lindmo, T.3
-
42
-
-
0027989606
-
A characteristic sequence of trisomies starting with trisomy 7 in benign thyroid tumors
-
Belge G., Thode B., Rippe V., et al. A characteristic sequence of trisomies starting with trisomy 7 in benign thyroid tumors. Hum Genet 94 2 (1994) 198-202
-
(1994)
Hum Genet
, vol.94
, Issue.2
, pp. 198-202
-
-
Belge, G.1
Thode, B.2
Rippe, V.3
-
43
-
-
0031664987
-
Comparison of benign and malignant follicular thyroid tumours by comparative genomic hybridization
-
Hemmer S., Wasenius V.M., Knuutila S., et al. Comparison of benign and malignant follicular thyroid tumours by comparative genomic hybridization. Br J Cancer 78 8 (1998) 1012-1017
-
(1998)
Br J Cancer
, vol.78
, Issue.8
, pp. 1012-1017
-
-
Hemmer, S.1
Wasenius, V.M.2
Knuutila, S.3
-
44
-
-
0032828356
-
Interphase cytogenetic analysis of normal tissue of thyroid gland by fluorescence in situ hybridization
-
Barril N., Carvalho-Sales A.B., and Tajara E.H. Interphase cytogenetic analysis of normal tissue of thyroid gland by fluorescence in situ hybridization. Cancer Genet Cytogenet 114 2 (1999) 162-164
-
(1999)
Cancer Genet Cytogenet
, vol.114
, Issue.2
, pp. 162-164
-
-
Barril, N.1
Carvalho-Sales, A.B.2
Tajara, E.H.3
-
45
-
-
0035074949
-
Fetal adenomas and minimally invasive follicular carcinomas of the thyroid frequently display a triploid or near triploid DNA pattern
-
Castro P., Sansonetty F., Soares P., et al. Fetal adenomas and minimally invasive follicular carcinomas of the thyroid frequently display a triploid or near triploid DNA pattern. Virchows Arch 438 4 (2001) 336-342
-
(2001)
Virchows Arch
, vol.438
, Issue.4
, pp. 336-342
-
-
Castro, P.1
Sansonetty, F.2
Soares, P.3
-
46
-
-
0026081996
-
DNA aneuploidy in follicular thyroid neoplasia
-
Cusick E.L., Ewen S.W., Krukowski Z.H., et al. DNA aneuploidy in follicular thyroid neoplasia. Br J Surg 78 1 (1991) 94-96
-
(1991)
Br J Surg
, vol.78
, Issue.1
, pp. 94-96
-
-
Cusick, E.L.1
Ewen, S.W.2
Krukowski, Z.H.3
-
47
-
-
0025017228
-
Frequency and degree of aneuploidy in benign and malignant thyroid neoplasms
-
Schelfhout L.J., Cornelisse C.J., Goslings B.M., et al. Frequency and degree of aneuploidy in benign and malignant thyroid neoplasms. Int J Cancer 45 1 (1990) 16-20
-
(1990)
Int J Cancer
, vol.45
, Issue.1
, pp. 16-20
-
-
Schelfhout, L.J.1
Cornelisse, C.J.2
Goslings, B.M.3
-
48
-
-
0032533146
-
DNA ploidy in papillary carcinoma of the thyroid gland in children and adolescents
-
Stern Y., Segal K., Medalia O., et al. DNA ploidy in papillary carcinoma of the thyroid gland in children and adolescents. Int J Pediatr Otorhinolaryngol 46 1-2 (1998) 67-70
-
(1998)
Int J Pediatr Otorhinolaryngol
, vol.46
, Issue.1-2
, pp. 67-70
-
-
Stern, Y.1
Segal, K.2
Medalia, O.3
-
49
-
-
0023951007
-
A comparative study of DNA cytometry methods for benign and malignant thyroid tissue
-
Hostetter A.L., Hrafnkelsson J., Wingren S.O., et al. A comparative study of DNA cytometry methods for benign and malignant thyroid tissue. Am J Clin Pathol 89 6 (1988) 760-763
-
(1988)
Am J Clin Pathol
, vol.89
, Issue.6
, pp. 760-763
-
-
Hostetter, A.L.1
Hrafnkelsson, J.2
Wingren, S.O.3
-
50
-
-
0029010491
-
Recent advances in cytometry, cytogenetics and molecular genetics of thyroid tumours and tumour-like lesions
-
Soares P., and Sobrinho-Simões M. Recent advances in cytometry, cytogenetics and molecular genetics of thyroid tumours and tumour-like lesions. Pathol Res Pract 191 4 (1995) 304-317
-
(1995)
Pathol Res Pract
, vol.191
, Issue.4
, pp. 304-317
-
-
Soares, P.1
Sobrinho-Simões, M.2
-
51
-
-
0030831349
-
Heterogeneity of nuclear DNA pattern and its relationship with cell cycle activity parameters in multinodular goitre
-
Francia G., Azzolina L., Mantovani T., et al. Heterogeneity of nuclear DNA pattern and its relationship with cell cycle activity parameters in multinodular goitre. Clin Endocrinol (Oxf) 46 6 (1997) 649-654
-
(1997)
Clin Endocrinol (Oxf)
, vol.46
, Issue.6
, pp. 649-654
-
-
Francia, G.1
Azzolina, L.2
Mantovani, T.3
-
52
-
-
0022539856
-
Flow cytometric DNA measurements in human thyroid tumors
-
Christov K. Flow cytometric DNA measurements in human thyroid tumors. Virchows Arch B Cell Pathol Incl Mol Pathol 51 3 (1986) 255-263
-
(1986)
Virchows Arch B Cell Pathol Incl Mol Pathol
, vol.51
, Issue.3
, pp. 255-263
-
-
Christov, K.1
-
53
-
-
0025972629
-
Stereology, flow cytometry, and immunohistochemistry of follicular neoplasms of the thyroid gland
-
Schurmann G., Mattfeldt T., Feichter G., et al. Stereology, flow cytometry, and immunohistochemistry of follicular neoplasms of the thyroid gland. Hum Pathol 22 2 (1991) 179-184
-
(1991)
Hum Pathol
, vol.22
, Issue.2
, pp. 179-184
-
-
Schurmann, G.1
Mattfeldt, T.2
Feichter, G.3
-
54
-
-
21344452129
-
Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes
-
Castro P., Eknaes M., Teixeira M.R., et al. Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes. J Pathol 206 3 (2005) 305-311
-
(2005)
J Pathol
, vol.206
, Issue.3
, pp. 305-311
-
-
Castro, P.1
Eknaes, M.2
Teixeira, M.R.3
-
55
-
-
0023690656
-
DNA aneuploidy in adenomas of endocrine organs
-
Joensuu H., and Klemi P.J. DNA aneuploidy in adenomas of endocrine organs. Am J Pathol 132 1 (1988) 145-151
-
(1988)
Am J Pathol
, vol.132
, Issue.1
, pp. 145-151
-
-
Joensuu, H.1
Klemi, P.J.2
-
56
-
-
0033603629
-
Image analysis of papillary thyroid carcinoma fine-needle aspirates: significant association between aneuploidy and death from disease
-
Sturgis C.D., Caraway N.P., Johnston D.A., et al. Image analysis of papillary thyroid carcinoma fine-needle aspirates: significant association between aneuploidy and death from disease. Cancer 87 3 (1999) 155-160
-
(1999)
Cancer
, vol.87
, Issue.3
, pp. 155-160
-
-
Sturgis, C.D.1
Caraway, N.P.2
Johnston, D.A.3
-
57
-
-
0037358438
-
Chromosome imbalances in thyroid follicular neoplasms: a comparison between follicular adenomas and carcinomas
-
Roque L., Rodrigues R., Pinto A., et al. Chromosome imbalances in thyroid follicular neoplasms: a comparison between follicular adenomas and carcinomas. Genes Chromosomes Cancer 36 3 (2003) 292-302
-
(2003)
Genes Chromosomes Cancer
, vol.36
, Issue.3
, pp. 292-302
-
-
Roque, L.1
Rodrigues, R.2
Pinto, A.3
-
58
-
-
1342280436
-
Chromosomal imbalances associated with anaplastic transformation of follicular thyroid carcinomas
-
Rodrigues R.F., Roque L., Rosa-Santos J., et al. Chromosomal imbalances associated with anaplastic transformation of follicular thyroid carcinomas. Br J Cancer 90 2 (2004) 492-496
-
(2004)
Br J Cancer
, vol.90
, Issue.2
, pp. 492-496
-
-
Rodrigues, R.F.1
Roque, L.2
Rosa-Santos, J.3
-
59
-
-
23644459338
-
A subset of the follicular variant of papillary thyroid carcinoma harbors the PAX8-PPARgamma translocation
-
Castro P., Roque L., Magalhaes J., et al. A subset of the follicular variant of papillary thyroid carcinoma harbors the PAX8-PPARgamma translocation. Int J Surg Pathol 13 3 (2005) 235-238
-
(2005)
Int J Surg Pathol
, vol.13
, Issue.3
, pp. 235-238
-
-
Castro, P.1
Roque, L.2
Magalhaes, J.3
-
61
-
-
0029076415
-
Detection of numerical alterations for chromosomes 7 and 12 in benign thyroid lesions by in situ hybridization. Histological implications
-
Criado B., Barros A., Suijkerbuijk R.F., et al. Detection of numerical alterations for chromosomes 7 and 12 in benign thyroid lesions by in situ hybridization. Histological implications. Am J Pathol 147 1 (1995) 136-144
-
(1995)
Am J Pathol
, vol.147
, Issue.1
, pp. 136-144
-
-
Criado, B.1
Barros, A.2
Suijkerbuijk, R.F.3
-
62
-
-
0032007043
-
Cytogenetic investigations of 340 thyroid hyperplasias and adenomas revealing correlations between cytogenetic findings and histology
-
Belge G., Roque L., Soares J., et al. Cytogenetic investigations of 340 thyroid hyperplasias and adenomas revealing correlations between cytogenetic findings and histology. Cancer Genet Cytogenet 101 1 (1998) 42-48
-
(1998)
Cancer Genet Cytogenet
, vol.101
, Issue.1
, pp. 42-48
-
-
Belge, G.1
Roque, L.2
Soares, J.3
-
63
-
-
0035889953
-
Karyotypic characterization of papillary thyroid carcinomas
-
Roque L., Nunes V.M., Ribeiro C., et al. Karyotypic characterization of papillary thyroid carcinomas. Cancer 92 10 (2001) 2529-2538
-
(2001)
Cancer
, vol.92
, Issue.10
, pp. 2529-2538
-
-
Roque, L.1
Nunes, V.M.2
Ribeiro, C.3
-
64
-
-
28444485337
-
Molecular pathology of well-differentiated thyroid carcinomas
-
Sobrinho-Simões M., Preto A., Rocha A.S., et al. Molecular pathology of well-differentiated thyroid carcinomas. Virchows Arch 447 5 (2005) 787-793
-
(2005)
Virchows Arch
, vol.447
, Issue.5
, pp. 787-793
-
-
Sobrinho-Simões, M.1
Preto, A.2
Rocha, A.S.3
-
65
-
-
0036223590
-
Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1
-
Ouyang B., Knauf J.A., Ain K., et al. Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1. Clin Endocrinol (Oxf) 56 3 (2002) 341-350
-
(2002)
Clin Endocrinol (Oxf)
, vol.56
, Issue.3
, pp. 341-350
-
-
Ouyang, B.1
Knauf, J.A.2
Ain, K.3
-
66
-
-
23044442140
-
Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells
-
Kim D., Pemberton H., Stratford A.L., et al. Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells. Oncogene 24 30 (2005) 4861-4866
-
(2005)
Oncogene
, vol.24
, Issue.30
, pp. 4861-4866
-
-
Kim, D.1
Pemberton, H.2
Stratford, A.L.3
-
67
-
-
33746789351
-
H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid
-
Castro P., Soares P., Gusmao L., et al. H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid. Oncogene 25 33 (2006) 4620-4627
-
(2006)
Oncogene
, vol.25
, Issue.33
, pp. 4620-4627
-
-
Castro, P.1
Soares, P.2
Gusmao, L.3
-
68
-
-
0034714190
-
PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma
-
[corrected]
-
Kroll T.G., Sarraf P., Pecciarini L., et al. PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma. [corrected]. Science 289 5483 (2000) 1357-1360
-
(2000)
Science
, vol.289
, Issue.5483
, pp. 1357-1360
-
-
Kroll, T.G.1
Sarraf, P.2
Pecciarini, L.3
-
69
-
-
0036344885
-
Expression of PAX8-PPAR gamma 1 rearrangements in both follicular thyroid carcinomas and adenomas
-
Marques A.R., Espadinha C., Catarino A.L., et al. Expression of PAX8-PPAR gamma 1 rearrangements in both follicular thyroid carcinomas and adenomas. J Clin Endocrinol Metab 87 8 (2002) 3947-3952
-
(2002)
J Clin Endocrinol Metab
, vol.87
, Issue.8
, pp. 3947-3952
-
-
Marques, A.R.1
Espadinha, C.2
Catarino, A.L.3
-
70
-
-
0037238701
-
Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas
-
Cheung L., Messina M., Gill A., et al. Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas. J Clin Endocrinol Metab 88 1 (2003) 354-357
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.1
, pp. 354-357
-
-
Cheung, L.1
Messina, M.2
Gill, A.3
-
71
-
-
0027330108
-
Deletion of 3p25-->pter in a primary follicular thyroid carcinoma and its metastasis
-
Roque L., Castedo S., Clode A., et al. Deletion of 3p25-->pter in a primary follicular thyroid carcinoma and its metastasis. Genes Chromosomes Cancer 8 3 (1993) 199-203
-
(1993)
Genes Chromosomes Cancer
, vol.8
, Issue.3
, pp. 199-203
-
-
Roque, L.1
Castedo, S.2
Clode, A.3
-
72
-
-
0027070675
-
A t(2;3)(q12-13;p24-25) in follicular thyroid adenomas
-
Sozzi G., Miozzo M., Cariani T.C., et al. A t(2;3)(q12-13;p24-25) in follicular thyroid adenomas. Cancer Genet Cytogenet 64 1 (1992) 38-41
-
(1992)
Cancer Genet Cytogenet
, vol.64
, Issue.1
, pp. 38-41
-
-
Sozzi, G.1
Miozzo, M.2
Cariani, T.C.3
-
73
-
-
0025035484
-
Frequent occurrence of cytogenetic abnormalities in sporadic nonmedullary thyroid carcinoma
-
Jenkins R.B., Hay I.D., Herath J.F., et al. Frequent occurrence of cytogenetic abnormalities in sporadic nonmedullary thyroid carcinoma. Cancer 66 6 (1990) 1213-1220
-
(1990)
Cancer
, vol.66
, Issue.6
, pp. 1213-1220
-
-
Jenkins, R.B.1
Hay, I.D.2
Herath, J.F.3
-
74
-
-
0343294296
-
Balanced translocation (3;7)(p25;q34): another mechanism of tumorigenesis in follicular thyroid carcinoma?
-
Lui W.O., Kytola S., Anfalk L., et al. Balanced translocation (3;7)(p25;q34): another mechanism of tumorigenesis in follicular thyroid carcinoma?. Cancer Genet Cytogenet 119 2 (2000) 109-112
-
(2000)
Cancer Genet Cytogenet
, vol.119
, Issue.2
, pp. 109-112
-
-
Lui, W.O.1
Kytola, S.2
Anfalk, L.3
-
75
-
-
2442697906
-
The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition
-
Gregory Powell J., Wang X., Allard B.L., et al. The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition. Oncogene 23 20 (2004) 3634-3641
-
(2004)
Oncogene
, vol.23
, Issue.20
, pp. 3634-3641
-
-
Gregory Powell, J.1
Wang, X.2
Allard, B.L.3
-
76
-
-
20144367845
-
Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines
-
Park J.W., Zarnegar R., Kanauchi H., et al. Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines. Thyroid 15 3 (2005) 222-231
-
(2005)
Thyroid
, vol.15
, Issue.3
, pp. 222-231
-
-
Park, J.W.1
Zarnegar, R.2
Kanauchi, H.3
-
77
-
-
21244436087
-
Follicular thyroid tumors with the PAX8-PPARgamma1 rearrangement display characteristic genetic alterations
-
Lacroix L., Lazar V., Michiels S., et al. Follicular thyroid tumors with the PAX8-PPARgamma1 rearrangement display characteristic genetic alterations. Am J Pathol 167 1 (2005) 223-231
-
(2005)
Am J Pathol
, vol.167
, Issue.1
, pp. 223-231
-
-
Lacroix, L.1
Lazar, V.2
Michiels, S.3
-
78
-
-
4344592171
-
Underexpression of peroxisome proliferator-activated receptor (PPAR)gamma in PAX8/PPARgamma-negative thyroid tumours
-
Marques A.R., Espadinha C., Frias M.J., et al. Underexpression of peroxisome proliferator-activated receptor (PPAR)gamma in PAX8/PPARgamma-negative thyroid tumours. Br J Cancer 91 4 (2004) 732-738
-
(2004)
Br J Cancer
, vol.91
, Issue.4
, pp. 732-738
-
-
Marques, A.R.1
Espadinha, C.2
Frias, M.J.3
-
79
-
-
18144377130
-
PPARgamma staining as a surrogate for PAX8/PPARgamma fusion oncogene expression in follicular neoplasms: clinicopathological correlation and histopathological diagnostic value
-
Sahin M., Allard B.L., Yates M., et al. PPARgamma staining as a surrogate for PAX8/PPARgamma fusion oncogene expression in follicular neoplasms: clinicopathological correlation and histopathological diagnostic value. J Clin Endocrinol Metab 90 1 (2005) 463-468
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.1
, pp. 463-468
-
-
Sahin, M.1
Allard, B.L.2
Yates, M.3
-
80
-
-
0037379904
-
High Prevalence of BRAF Mutations in Thyroid Cancer: Genetic Evidence for Constitutive Activation of the RET/PTC-RAS-BRAF Signaling Pathway in Papillary Thyroid Carcinoma
-
Kimura E.T., Nikiforova M.N., Zhu Z., et al. High Prevalence of BRAF Mutations in Thyroid Cancer: Genetic Evidence for Constitutive Activation of the RET/PTC-RAS-BRAF Signaling Pathway in Papillary Thyroid Carcinoma. Cancer Res 63 7 (2003) 1454-1457
-
(2003)
Cancer Res
, vol.63
, Issue.7
, pp. 1454-1457
-
-
Kimura, E.T.1
Nikiforova, M.N.2
Zhu, Z.3
-
81
-
-
0043170833
-
BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC
-
Soares P., Trovisco V., Rocha A.S., et al. BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC. Oncogene 22 29 (2003) 4578-4580
-
(2003)
Oncogene
, vol.22
, Issue.29
, pp. 4578-4580
-
-
Soares, P.1
Trovisco, V.2
Rocha, A.S.3
-
82
-
-
9144219691
-
Mutations of the BRAF gene in papillary thyroid carcinoma in a Korean population
-
Kim K.H., Kang D.W., Kim S.H., et al. Mutations of the BRAF gene in papillary thyroid carcinoma in a Korean population. Yonsei Med J 45 5 (2004) 818-821
-
(2004)
Yonsei Med J
, vol.45
, Issue.5
, pp. 818-821
-
-
Kim, K.H.1
Kang, D.W.2
Kim, S.H.3
-
83
-
-
6044219917
-
Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer
-
Frattini M., Ferrario C., Bressan P., et al. Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer. Oncogene 23 44 (2004) 7436-7440
-
(2004)
Oncogene
, vol.23
, Issue.44
, pp. 7436-7440
-
-
Frattini, M.1
Ferrario, C.2
Bressan, P.3
-
84
-
-
2442568538
-
V599E Mutation Is the Leading Genetic Event in Adult Sporadic Papillary Thyroid Carcinomas
-
V599E Mutation Is the Leading Genetic Event in Adult Sporadic Papillary Thyroid Carcinomas. J Clin Endocrinol Metab 89 5 (2004) 2414-2420
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.5
, pp. 2414-2420
-
-
Puxeddu, E.1
Moretti, S.2
Elisei, R.3
-
85
-
-
30944445020
-
BRAF mediates RET/PTC-induced MAPK activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis
-
Mitsutake N., Miyagishi M., Mitsutake S., et al. BRAF mediates RET/PTC-induced MAPK activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis. Endocrinology 147 2 (2006) 1014-1019
-
(2006)
Endocrinology
, vol.147
, Issue.2
, pp. 1014-1019
-
-
Mitsutake, N.1
Miyagishi, M.2
Mitsutake, S.3
-
86
-
-
20144387455
-
The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells
-
Melillo R.M., Castellone M.D., Guarino V., et al. The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells. J Clin Invest 115 4 (2005) 1068-1081
-
(2005)
J Clin Invest
, vol.115
, Issue.4
, pp. 1068-1081
-
-
Melillo, R.M.1
Castellone, M.D.2
Guarino, V.3
-
87
-
-
10744222003
-
BRAF Mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas
-
Nikiforova M.N., Kimura E.T., Gandhi M., et al. BRAF Mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas. J Clin Endocrinol Metab 88 11 (2003) 5399-5404
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.11
, pp. 5399-5404
-
-
Nikiforova, M.N.1
Kimura, E.T.2
Gandhi, M.3
-
88
-
-
21544464303
-
Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients' age but not with tumour aggressiveness
-
Trovisco V., Soares P., Preto A., et al. Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients' age but not with tumour aggressiveness. Virchows Arch 446 6 (2005) 589-595
-
(2005)
Virchows Arch
, vol.446
, Issue.6
, pp. 589-595
-
-
Trovisco, V.1
Soares, P.2
Preto, A.3
-
89
-
-
1142287286
-
BRAF mutations are associated with some histological types of papillary thyroid carcinoma
-
Trovisco V., Vieira D.C.I., Soares P., et al. BRAF mutations are associated with some histological types of papillary thyroid carcinoma. J Pathol 202 2 (2004) 247-251
-
(2004)
J Pathol
, vol.202
, Issue.2
, pp. 247-251
-
-
Trovisco, V.1
Vieira, D.C.I.2
Soares, P.3
-
90
-
-
4143051232
-
BRAF mutations in an Italian cohort of thyroid cancers
-
Fugazzola L., Mannavola D., Cirello V., et al. BRAF mutations in an Italian cohort of thyroid cancers. Clin Endocrinol (Oxf) 61 2 (2004) 239-243
-
(2004)
Clin Endocrinol (Oxf)
, vol.61
, Issue.2
, pp. 239-243
-
-
Fugazzola, L.1
Mannavola, D.2
Cirello, V.3
-
91
-
-
21544476746
-
A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma
-
Trovisco V., Soares P., Soares R., et al. A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma. Hum Pathol 36 6 (2005) 694-697
-
(2005)
Hum Pathol
, vol.36
, Issue.6
, pp. 694-697
-
-
Trovisco, V.1
Soares, P.2
Soares, R.3
-
92
-
-
17044395065
-
Investigation of BRAF mutation in a series of papillary thyroid carcinoma and matched-lymph node metastasis reveals a new mutation in metastasis
-
Oler G., Ebina K.N., Michaluart Jr. P., et al. Investigation of BRAF mutation in a series of papillary thyroid carcinoma and matched-lymph node metastasis reveals a new mutation in metastasis. Clin Endocrinol (Oxf) 62 4 (2005) 509-511
-
(2005)
Clin Endocrinol (Oxf)
, vol.62
, Issue.4
, pp. 509-511
-
-
Oler, G.1
Ebina, K.N.2
Michaluart Jr., P.3
-
93
-
-
33644947163
-
Genotyping of an Italian papillary thyroid carcinoma cohort revealed high prevalence of BRAF mutations, absence of RAS mutations and allowed the detection of a new mutation of BRAF oncoprotein (BRAF(V599lns)
-
Carta C., Moretti S., Passeri L., et al. Genotyping of an Italian papillary thyroid carcinoma cohort revealed high prevalence of BRAF mutations, absence of RAS mutations and allowed the detection of a new mutation of BRAF oncoprotein (BRAF(V599lns). Clin Endocrinol (Oxf) 64 1 (2006) 105-109
-
(2006)
Clin Endocrinol (Oxf)
, vol.64
, Issue.1
, pp. 105-109
-
-
Carta, C.1
Moretti, S.2
Passeri, L.3
-
94
-
-
33847068350
-
Functional characterization of the T1799-1801del and A1799-1816ins BRAF mutations in papillary thyroid cancer
-
Hou P., Liu D., and Xing M. Functional characterization of the T1799-1801del and A1799-1816ins BRAF mutations in papillary thyroid cancer. Cell Cycle 6 3 (2007) 377-379
-
(2007)
Cell Cycle
, vol.6
, Issue.3
, pp. 377-379
-
-
Hou, P.1
Liu, D.2
Xing, M.3
-
95
-
-
34047260938
-
BRAF T1799A mutation occurring in a case of malignant struma ovarii
-
Flavin R., Smyth P., Crotty P., et al. BRAF T1799A mutation occurring in a case of malignant struma ovarii. Int J Surg Pathol 15 2 (2007) 116-120
-
(2007)
Int J Surg Pathol
, vol.15
, Issue.2
, pp. 116-120
-
-
Flavin, R.1
Smyth, P.2
Crotty, P.3
-
96
-
-
34548287649
-
BRAF in papillary thyroid carcinoma of ovary (Struma Ovarii)
-
Schmidt J., Derr V., Heinrich M.C., et al. BRAF in papillary thyroid carcinoma of ovary (Struma Ovarii). Am J Surg Pathol 31 9 (2007) 1337-1343
-
(2007)
Am J Surg Pathol
, vol.31
, Issue.9
, pp. 1337-1343
-
-
Schmidt, J.1
Derr, V.2
Heinrich, M.C.3
-
97
-
-
12144289677
-
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
-
Wan P.T., Garnett M.J., Roe S.M., et al. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 116 6 (2004) 855-867
-
(2004)
Cell
, vol.116
, Issue.6
, pp. 855-867
-
-
Wan, P.T.1
Garnett, M.J.2
Roe, S.M.3
-
98
-
-
0036144208
-
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma
-
Basolo F., Giannini R., Monaco C., et al. Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma. Am J Pathol 160 1 (2002) 247-254
-
(2002)
Am J Pathol
, vol.160
, Issue.1
, pp. 247-254
-
-
Basolo, F.1
Giannini, R.2
Monaco, C.3
-
99
-
-
16644384144
-
The BRAFT1796A transversion is a prevalent mutational event in human thyroid microcarcinoma
-
Sedliarou I., Saenko V., Lantsov D., et al. The BRAFT1796A transversion is a prevalent mutational event in human thyroid microcarcinoma. Int J Oncol 25 6 (2004) 1729-1735
-
(2004)
Int J Oncol
, vol.25
, Issue.6
, pp. 1729-1735
-
-
Sedliarou, I.1
Saenko, V.2
Lantsov, D.3
-
100
-
-
27744512441
-
The BRAF mutation is not associated with poor prognostic factors in Korean patients with conventional papillary thyroid microcarcinoma
-
Kim T.Y., Kim W.B., Song J.Y., et al. The BRAF mutation is not associated with poor prognostic factors in Korean patients with conventional papillary thyroid microcarcinoma. Clin Endocrinol (Oxf) 63 5 (2005) 588-593
-
(2005)
Clin Endocrinol (Oxf)
, vol.63
, Issue.5
, pp. 588-593
-
-
Kim, T.Y.1
Kim, W.B.2
Song, J.Y.3
-
101
-
-
34249940475
-
Presence of BRAF V600E in Very Early Stages of Papillary Thyroid Carcinoma
-
Ugolini C., Giannini R., Lupi C., et al. Presence of BRAF V600E in Very Early Stages of Papillary Thyroid Carcinoma. Thyroid 17 5 (2007) 381-388
-
(2007)
Thyroid
, vol.17
, Issue.5
, pp. 381-388
-
-
Ugolini, C.1
Giannini, R.2
Lupi, C.3
-
102
-
-
20144372793
-
Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation
-
Knauf J.A., Ma X., Smith E.P., et al. Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation. Cancer Res 65 10 (2005) 4238-4245
-
(2005)
Cancer Res
, vol.65
, Issue.10
, pp. 4238-4245
-
-
Knauf, J.A.1
Ma, X.2
Smith, E.P.3
-
103
-
-
34347208361
-
BRAF V600E maintains proliferation, transformation, and tumorigenicity of BRAF-mutant papillary thyroid cancer cells
-
Liu D., Liu Z., Condouris S., et al. BRAF V600E maintains proliferation, transformation, and tumorigenicity of BRAF-mutant papillary thyroid cancer cells. J Clin Endocrinol Metab 92 6 (2007) 2264-2271
-
(2007)
J Clin Endocrinol Metab
, vol.92
, Issue.6
, pp. 2264-2271
-
-
Liu, D.1
Liu, Z.2
Condouris, S.3
-
104
-
-
33745074644
-
Correlation between B-RAFV600E mutation and clinico-pathologic parameters in papillary thyroid carcinoma: data from a multicentric Italian study and review of the literature
-
Fugazzola L., Puxeddu E., Avenia N., et al. Correlation between B-RAFV600E mutation and clinico-pathologic parameters in papillary thyroid carcinoma: data from a multicentric Italian study and review of the literature. Endocr Relat Cancer 13 2 (2006) 455-464
-
(2006)
Endocr Relat Cancer
, vol.13
, Issue.2
, pp. 455-464
-
-
Fugazzola, L.1
Puxeddu, E.2
Avenia, N.3
-
105
-
-
0041589377
-
High Prevalence of BRAF Gene Mutation in Papillary Thyroid Carcinomas and Thyroid Tumor Cell Lines
-
Xu X., Quiros R.M., Gattuso P., et al. High Prevalence of BRAF Gene Mutation in Papillary Thyroid Carcinomas and Thyroid Tumor Cell Lines. Cancer Res 63 15 (2003) 4561-4567
-
(2003)
Cancer Res
, vol.63
, Issue.15
, pp. 4561-4567
-
-
Xu, X.1
Quiros, R.M.2
Gattuso, P.3
-
106
-
-
33747369828
-
The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma
-
Kim T.Y., Kim W.B., Rhee Y.S., et al. The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma. Clin Endocrinol (Oxf) 65 3 (2006) 364-368
-
(2006)
Clin Endocrinol (Oxf)
, vol.65
, Issue.3
, pp. 364-368
-
-
Kim, T.Y.1
Kim, W.B.2
Rhee, Y.S.3
-
107
-
-
33748291679
-
BRAF mutation analysis in fine needle aspiration (FNA) cytology of the thyroid
-
Jin L., Sebo T.J., Nakamura N., et al. BRAF mutation analysis in fine needle aspiration (FNA) cytology of the thyroid. Diagn Mol Pathol 15 3 (2006) 136-143
-
(2006)
Diagn Mol Pathol
, vol.15
, Issue.3
, pp. 136-143
-
-
Jin, L.1
Sebo, T.J.2
Nakamura, N.3
-
108
-
-
28744442816
-
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer
-
Xing M., Westra W.H., Tufano R.P., et al. BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer. J Clin Endocrinol Metab 90 12 (2005) 6373-6379
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.12
, pp. 6373-6379
-
-
Xing, M.1
Westra, W.H.2
Tufano, R.P.3
-
109
-
-
0141453014
-
Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers
-
Namba H., Nakashima M., Hayashi T., et al. Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers. J Clin Endocrinol Metab 88 9 (2003) 4393-4397
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.9
, pp. 4393-4397
-
-
Namba, H.1
Nakashima, M.2
Hayashi, T.3
-
110
-
-
26644473629
-
No correlation between BRAFV600E mutation and clinicopathological features of papillary thyroid carcinomas in Taiwan
-
Liu R.T., Chen Y.J., Chou F.F., et al. No correlation between BRAFV600E mutation and clinicopathological features of papillary thyroid carcinomas in Taiwan. Clin Endocrinol (Oxf) 63 4 (2005) 461-466
-
(2005)
Clin Endocrinol (Oxf)
, vol.63
, Issue.4
, pp. 461-466
-
-
Liu, R.T.1
Chen, Y.J.2
Chou, F.F.3
-
111
-
-
33750068250
-
Detection of BRAFV600E mutation on fine needle aspiration specimens of thyroid nodule refines cyto-pathology diagnosis, especially in BRAF600E mutation-prevalent area
-
Chung K.W., Yang S.K., Lee G.K., et al. Detection of BRAFV600E mutation on fine needle aspiration specimens of thyroid nodule refines cyto-pathology diagnosis, especially in BRAF600E mutation-prevalent area. Clin Endocrinol (Oxf) 65 5 (2006) 660-666
-
(2006)
Clin Endocrinol (Oxf)
, vol.65
, Issue.5
, pp. 660-666
-
-
Chung, K.W.1
Yang, S.K.2
Lee, G.K.3
-
112
-
-
33644586429
-
Detection of BRAF mutation in thyroid papillary carcinomas by mutant allele-specific PCR amplification (MASA)
-
Sapio M.R., Posca D., Troncone G., et al. Detection of BRAF mutation in thyroid papillary carcinomas by mutant allele-specific PCR amplification (MASA). Eur J Endocrinol 154 2 (2006) 341-348
-
(2006)
Eur J Endocrinol
, vol.154
, Issue.2
, pp. 341-348
-
-
Sapio, M.R.1
Posca, D.2
Troncone, G.3
-
113
-
-
33745136727
-
B-RAF mutations in the etiopathogenesis, diagnosis, and prognosis of thyroid carcinomas
-
Trovisco V., Soares P., and Sobrinho-Simões M. B-RAF mutations in the etiopathogenesis, diagnosis, and prognosis of thyroid carcinomas. Hum Pathol 37 7 (2006) 781-786
-
(2006)
Hum Pathol
, vol.37
, Issue.7
, pp. 781-786
-
-
Trovisco, V.1
Soares, P.2
Sobrinho-Simões, M.3
-
114
-
-
24344505403
-
High prevalence and possible de novo formation of BRAF mutation in metastasized papillary thyroid cancer in lymph nodes
-
Vasko V., Hu S., Wu G., et al. High prevalence and possible de novo formation of BRAF mutation in metastasized papillary thyroid cancer in lymph nodes. J Clin Endocrinol Metab 90 9 (2005) 5265-5269
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.9
, pp. 5265-5269
-
-
Vasko, V.1
Hu, S.2
Wu, G.3
-
115
-
-
33750308218
-
Lymphatic mapping establishes the role of BRAF gene mutation in papillary thyroid carcinoma
-
Kim J., Giuliano A.E., Turner R.R., et al. Lymphatic mapping establishes the role of BRAF gene mutation in papillary thyroid carcinoma. Ann Surg 244 5 (2006) 799-804
-
(2006)
Ann Surg
, vol.244
, Issue.5
, pp. 799-804
-
-
Kim, J.1
Giuliano, A.E.2
Turner, R.R.3
-
116
-
-
43849087055
-
-
Trovisco V, Couto JP, Cameselle-Teijeiro J, et al. Aquisition of BRAF gene mutations is not a requirement for nodal metastization of PTC. Clin Endocrinology, in press.
-
Trovisco V, Couto JP, Cameselle-Teijeiro J, et al. Aquisition of BRAF gene mutations is not a requirement for nodal metastization of PTC. Clin Endocrinology, in press.
-
-
-
-
117
-
-
1942470097
-
Mutational analysis of BRAF in fine needle aspiration biopsies of the thyroid: a potential application for the preoperative assessment of thyroid nodules
-
Cohen Y., Rosenbaum E., Clark D.P., et al. Mutational analysis of BRAF in fine needle aspiration biopsies of the thyroid: a potential application for the preoperative assessment of thyroid nodules. Clin Cancer Res 10 8 (2004) 2761-2765
-
(2004)
Clin Cancer Res
, vol.10
, Issue.8
, pp. 2761-2765
-
-
Cohen, Y.1
Rosenbaum, E.2
Clark, D.P.3
-
118
-
-
2942692120
-
Detection of BRAF mutation on fine needle aspiration biopsy specimens: a new diagnostic tool for papillary thyroid cancer
-
Xing M., Tufano R.P., Tufaro A.P., et al. Detection of BRAF mutation on fine needle aspiration biopsy specimens: a new diagnostic tool for papillary thyroid cancer. J Clin Endocrinol Metab 89 6 (2004) 2867-2872
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.6
, pp. 2867-2872
-
-
Xing, M.1
Tufano, R.P.2
Tufaro, A.P.3
-
119
-
-
10044286181
-
A rapid and simple detection method for the BRAF(T1796A) mutation in fine-needle aspirated thyroid carcinoma cells
-
Hayashida N., Namba H., Kumagai A., et al. A rapid and simple detection method for the BRAF(T1796A) mutation in fine-needle aspirated thyroid carcinoma cells. Thyroid 14 11 (2004) 910-915
-
(2004)
Thyroid
, vol.14
, Issue.11
, pp. 910-915
-
-
Hayashida, N.1
Namba, H.2
Kumagai, A.3
-
120
-
-
6344231395
-
Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma
-
Salvatore G., Giannini R., Faviana P., et al. Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma. J Clin Endocrinol Metab 89 10 (2004) 5175-5180
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.10
, pp. 5175-5180
-
-
Salvatore, G.1
Giannini, R.2
Faviana, P.3
-
121
-
-
14344250602
-
Searching for RET/PTC rearrangements and BRAF V599E mutation in thyroid aspirates might contribute to establish a preoperative diagnosis of papillary thyroid carcinoma
-
Domingues R., Mendonca E., Sobrinho L., et al. Searching for RET/PTC rearrangements and BRAF V599E mutation in thyroid aspirates might contribute to establish a preoperative diagnosis of papillary thyroid carcinoma. Cytopathology 16 1 (2005) 27-31
-
(2005)
Cytopathology
, vol.16
, Issue.1
, pp. 27-31
-
-
Domingues, R.1
Mendonca, E.2
Sobrinho, L.3
-
122
-
-
0032948862
-
Follicular variant of papillary carcinoma. Cytologic and histologic correlation
-
Baloch Z.W., Gupta P.K., Yu G.H., et al. Follicular variant of papillary carcinoma. Cytologic and histologic correlation. Am J Clin Pathol 111 2 (1999) 216-222
-
(1999)
Am J Clin Pathol
, vol.111
, Issue.2
, pp. 216-222
-
-
Baloch, Z.W.1
Gupta, P.K.2
Yu, G.H.3
-
123
-
-
0036632771
-
Cancer after nuclear fallout: lessons from the Chernobyl accident
-
Williams D. Cancer after nuclear fallout: lessons from the Chernobyl accident. Nat Rev Cancer 2 7 (2002) 543-549
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.7
, pp. 543-549
-
-
Williams, D.1
-
124
-
-
0030941779
-
Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children
-
Nikiforov Y.E., Rowland J.M., Bove K.E., et al. Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children. Cancer Res 57 9 (1997) 1690-1694
-
(1997)
Cancer Res
, vol.57
, Issue.9
, pp. 1690-1694
-
-
Nikiforov, Y.E.1
Rowland, J.M.2
Bove, K.E.3
-
125
-
-
2442642971
-
Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas
-
Nikiforova M.N., Ciampi R., Salvatore G., et al. Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas. Cancer Lett 209 1 (2004) 1-6
-
(2004)
Cancer Lett
, vol.209
, Issue.1
, pp. 1-6
-
-
Nikiforova, M.N.1
Ciampi, R.2
Salvatore, G.3
-
126
-
-
4544324693
-
BRAF Mutations Are Not a Major Event in Post-Chernobyl Childhood Thyroid Carcinomas
-
Lima J., Trovisco V., Soares P., et al. BRAF Mutations Are Not a Major Event in Post-Chernobyl Childhood Thyroid Carcinomas. J Clin Endocrinol Metab 89 9 (2004) 4267-4271
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.9
, pp. 4267-4271
-
-
Lima, J.1
Trovisco, V.2
Soares, P.3
-
127
-
-
4544314992
-
Low Frequency of BRAFT1796A Mutations in Childhood Thyroid Carcinomas
-
Kumagai A., Namba H., Saenko V.A., et al. Low Frequency of BRAFT1796A Mutations in Childhood Thyroid Carcinomas. J Clin Endocrinol Metab 89 9 (2004) 4280-4284
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.9
, pp. 4280-4284
-
-
Kumagai, A.1
Namba, H.2
Saenko, V.A.3
-
128
-
-
17844394699
-
Dose-dependent generation of RET/PTC in human thyroid cells after in vitro exposure to gamma-radiation: a model of carcinogenic chromosomal rearrangement induced by ionizing radiation
-
Caudill C.M., Zhu Z., Ciampi R., et al. Dose-dependent generation of RET/PTC in human thyroid cells after in vitro exposure to gamma-radiation: a model of carcinogenic chromosomal rearrangement induced by ionizing radiation. J Clin Endocrinol Metab 90 4 (2005) 2364-2369
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.4
, pp. 2364-2369
-
-
Caudill, C.M.1
Zhu, Z.2
Ciampi, R.3
-
129
-
-
85047691154
-
Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer
-
Ciampi R., Knauf J.A., Kerler R., et al. Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer. J Clin Invest 115 1 (2005) 94-101
-
(2005)
J Clin Invest
, vol.115
, Issue.1
, pp. 94-101
-
-
Ciampi, R.1
Knauf, J.A.2
Kerler, R.3
-
130
-
-
0141815693
-
Regulation of Raf through phosphorylation and N terminus-C terminus interaction
-
Chong H., and Guan K.L. Regulation of Raf through phosphorylation and N terminus-C terminus interaction. J Biol Chem 278 38 (2003) 36269-36276
-
(2003)
J Biol Chem
, vol.278
, Issue.38
, pp. 36269-36276
-
-
Chong, H.1
Guan, K.L.2
-
131
-
-
0037500256
-
Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition
-
Tran N.H., and Frost J.A. Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition. J Biol Chem 278 13 (2003) 11221-11226
-
(2003)
J Biol Chem
, vol.278
, Issue.13
, pp. 11221-11226
-
-
Tran, N.H.1
Frost, J.A.2
-
132
-
-
18144373477
-
B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms
-
Tran N.H., Wu X., and Frost J.A. B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms. J Biol Chem 280 16 (2005) 16244-16253
-
(2005)
J Biol Chem
, vol.280
, Issue.16
, pp. 16244-16253
-
-
Tran, N.H.1
Wu, X.2
Frost, J.A.3
-
133
-
-
18744402183
-
BRAF mutations are uncommon in papillary thyroid cancer of young patients
-
Penko K., Livezey J., Fenton C., et al. BRAF mutations are uncommon in papillary thyroid cancer of young patients. Thyroid 15 4 (2005) 320-325
-
(2005)
Thyroid
, vol.15
, Issue.4
, pp. 320-325
-
-
Penko, K.1
Livezey, J.2
Fenton, C.3
-
134
-
-
17144394374
-
Frequency of BRAF T1796A mutation in papillary thyroid carcinoma relates to age of patient at diagnosis and not to radiation exposure
-
Powell N., Jeremiah S., Morishita M., et al. Frequency of BRAF T1796A mutation in papillary thyroid carcinoma relates to age of patient at diagnosis and not to radiation exposure. J Pathol 205 5 (2005) 558-564
-
(2005)
J Pathol
, vol.205
, Issue.5
, pp. 558-564
-
-
Powell, N.1
Jeremiah, S.2
Morishita, M.3
-
135
-
-
33947095518
-
The presence of BRAF point mutation in adult papillary thyroid carcinomas from atomic bomb survivors correlates with radiation dose
-
Takahashi K., Eguchi H., Arihiro K., et al. The presence of BRAF point mutation in adult papillary thyroid carcinomas from atomic bomb survivors correlates with radiation dose. Mol Carcinog 46 3 (2007) 242-248
-
(2007)
Mol Carcinog
, vol.46
, Issue.3
, pp. 242-248
-
-
Takahashi, K.1
Eguchi, H.2
Arihiro, K.3
-
136
-
-
21644440921
-
Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery
-
Thompson N., and Lyons J. Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery. Curr Opin Pharmacol 5 4 (2005) 350-356
-
(2005)
Curr Opin Pharmacol
, vol.5
, Issue.4
, pp. 350-356
-
-
Thompson, N.1
Lyons, J.2
-
137
-
-
33645069923
-
BRAF is a therapeutic target in aggressive thyroid carcinoma
-
Salvatore G., De Falco V., Salerno P., et al. BRAF is a therapeutic target in aggressive thyroid carcinoma. Clin Cancer Res 12 5 (2006) 1623-1629
-
(2006)
Clin Cancer Res
, vol.12
, Issue.5
, pp. 1623-1629
-
-
Salvatore, G.1
De Falco, V.2
Salerno, P.3
-
138
-
-
43849113816
-
-
Preto and colleagues, submitted.
-
Preto and colleagues, submitted.
-
-
-
-
139
-
-
33645698808
-
Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo
-
Ouyang B., Knauf J.A., Smith E.P., et al. Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo. Clin Cancer Res 12 6 (2006) 1785-1793
-
(2006)
Clin Cancer Res
, vol.12
, Issue.6
, pp. 1785-1793
-
-
Ouyang, B.1
Knauf, J.A.2
Smith, E.P.3
-
140
-
-
28244444919
-
Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin
-
da Rocha Dias S., Friedlos F., Light Y., et al. Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin. Cancer Res 65 23 (2005) 10686-10691
-
(2005)
Cancer Res
, vol.65
, Issue.23
, pp. 10686-10691
-
-
da Rocha Dias, S.1
Friedlos, F.2
Light, Y.3
-
141
-
-
30444441778
-
V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors
-
Grbovic O.M., Basso A.D., Sawai A., et al. V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors. Proc Natl Acad Sci USA 103 1 (2006) 57-62
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.1
, pp. 57-62
-
-
Grbovic, O.M.1
Basso, A.D.2
Sawai, A.3
-
142
-
-
0033623273
-
Hurthle cell tumours of the thyroid. A review with emphasis on mitochondrial abnormalities with clinical relevance
-
Máximo V., and Sobrinho-Simões M. Hurthle cell tumours of the thyroid. A review with emphasis on mitochondrial abnormalities with clinical relevance. Virchows Arch 437 2 (2000) 107-115
-
(2000)
Virchows Arch
, vol.437
, Issue.2
, pp. 107-115
-
-
Máximo, V.1
Sobrinho-Simões, M.2
-
143
-
-
0034335425
-
Molecular basis off Hürthle cell papillary thyroid carcinoma
-
Cheung C.C., Ezzat S., Ramyar L., et al. Molecular basis off Hürthle cell papillary thyroid carcinoma. J Clin Endocrinol Metab 85 2 (2000) 878-882
-
(2000)
J Clin Endocrinol Metab
, vol.85
, Issue.2
, pp. 878-882
-
-
Cheung, C.C.1
Ezzat, S.2
Ramyar, L.3
-
144
-
-
0036095510
-
Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors
-
Máximo V., Soares P., Lima J., et al. Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors. Am J Pathol 160 5 (2002) 1857-1865
-
(2002)
Am J Pathol
, vol.160
, Issue.5
, pp. 1857-1865
-
-
Máximo, V.1
Soares, P.2
Lima, J.3
-
145
-
-
34547480470
-
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors
-
Gasparre G., Porcelli A.M., Bonora E., et al. Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors. Proc Natl Acad Sci USA 104 21 (2007) 9001-9006
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.21
, pp. 9001-9006
-
-
Gasparre, G.1
Porcelli, A.M.2
Bonora, E.3
-
146
-
-
0031719197
-
The common deletion of mitochondrial DNA is found in goiters and thyroid tumors with and without oxyphil cell change
-
Máximo V., Soares P., Rocha A.S., et al. The common deletion of mitochondrial DNA is found in goiters and thyroid tumors with and without oxyphil cell change. Ultrastruct Pathol 22 3 (1998) 271-273
-
(1998)
Ultrastruct Pathol
, vol.22
, Issue.3
, pp. 271-273
-
-
Máximo, V.1
Soares, P.2
Rocha, A.S.3
-
147
-
-
0033673552
-
Mitochondrial DNA 'common' deletion in Hürthle cell lesions of the thyroid
-
Máximo V., and Sobrinho-Simões M. Mitochondrial DNA 'common' deletion in Hürthle cell lesions of the thyroid. J Pathol 192 4 (2000) 561-562
-
(2000)
J Pathol
, vol.192
, Issue.4
, pp. 561-562
-
-
Máximo, V.1
Sobrinho-Simões, M.2
-
148
-
-
0029003333
-
Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems
-
Attardi G., Yoneda M., and Chomyn A. Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems. Biochim Biophys Acta 1271 1 (1995) 241-248
-
(1995)
Biochim Biophys Acta
, vol.1271
, Issue.1
, pp. 241-248
-
-
Attardi, G.1
Yoneda, M.2
Chomyn, A.3
-
149
-
-
0000648576
-
Coordinate expression of nuclear and mitochondrial genes involved in energy production in carcinoma and oncocytoma
-
Heddi A., Faure-Vigny H., Wallace D.C., et al. Coordinate expression of nuclear and mitochondrial genes involved in energy production in carcinoma and oncocytoma. Biochim Biophys Acta 1316 3 (1996) 203-209
-
(1996)
Biochim Biophys Acta
, vol.1316
, Issue.3
, pp. 203-209
-
-
Heddi, A.1
Faure-Vigny, H.2
Wallace, D.C.3
-
150
-
-
13544270239
-
Hürthle (oncocytic) cell tumors of thyroid: etiopathogenesis, diagnosis and clinical significance
-
Sobrinho-Simões M., Máximo V., Castro I.V., et al. Hürthle (oncocytic) cell tumors of thyroid: etiopathogenesis, diagnosis and clinical significance. Int J Surg Pathol 13 1 (2005) 29-35
-
(2005)
Int J Surg Pathol
, vol.13
, Issue.1
, pp. 29-35
-
-
Sobrinho-Simões, M.1
Máximo, V.2
Castro, I.V.3
-
151
-
-
0034643388
-
Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours
-
Yeh J.J., Lunetta K.L., Van Orsouw N.J., et al. Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours. Oncogene 19 16 (2000) 2060-2066
-
(2000)
Oncogene
, vol.19
, Issue.16
, pp. 2060-2066
-
-
Yeh, J.J.1
Lunetta, K.L.2
Van Orsouw, N.J.3
-
152
-
-
0034721920
-
Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach
-
Angell J.E., Lindner D.J., Shapiro P.S., et al. Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach. J Biol Chem 275 43 (2000) 33416-33426
-
(2000)
J Biol Chem
, vol.275
, Issue.43
, pp. 33416-33426
-
-
Angell, J.E.1
Lindner, D.J.2
Shapiro, P.S.3
-
153
-
-
0033910295
-
Chromosomal localization of human GRIM-19, a novel IFN-beta and retinoic acid-activated regulator of cell death
-
Chidambaram N.V., Angell J.E., Ling W., et al. Chromosomal localization of human GRIM-19, a novel IFN-beta and retinoic acid-activated regulator of cell death. J Interferon Cytokine Res 20 7 (2000) 661-665
-
(2000)
J Interferon Cytokine Res
, vol.20
, Issue.7
, pp. 661-665
-
-
Chidambaram, N.V.1
Angell, J.E.2
Ling, W.3
-
154
-
-
0037451235
-
GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction
-
Lufei C., Ma J., Huang G., et al. GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction. EMBO J 22 6 (2003) 1325-1335
-
(2003)
EMBO J
, vol.22
, Issue.6
, pp. 1325-1335
-
-
Lufei, C.1
Ma, J.2
Huang, G.3
-
155
-
-
0035914435
-
GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I)
-
Fearnley I.M., Carroll J., Shannon R.J., et al. GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I). J Biol Chem 276 42 (2001) 38345-38348
-
(2001)
J Biol Chem
, vol.276
, Issue.42
, pp. 38345-38348
-
-
Fearnley, I.M.1
Carroll, J.2
Shannon, R.J.3
-
156
-
-
20344366798
-
Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hürthle cell) tumours of the thyroid
-
Máximo V., Botelho T., Capela J., et al. Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hürthle cell) tumours of the thyroid. Br J Cancer 92 10 (2005) 1982-1989
-
(2005)
Br J Cancer
, vol.92
, Issue.10
, pp. 1982-1989
-
-
Máximo, V.1
Botelho, T.2
Capela, J.3
-
157
-
-
43849106093
-
-
Lima J, Máximo V, Soares P, et al. Mitochondria and oncocytomas. In: Singh KK, editor. Mitochondria and Cancer. New York: Springer, in press.
-
Lima J, Máximo V, Soares P, et al. Mitochondria and oncocytomas. In: Singh KK, editor. Mitochondria and Cancer. New York: Springer, in press.
-
-
-
-
158
-
-
0037364314
-
A role for mitochondrial enzymes in inherited neoplasia and beyond
-
Eng C., Kiuru M., Fernandez M.J., et al. A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat Rev Cancer 3 3 (2003) 193-202
-
(2003)
Nat Rev Cancer
, vol.3
, Issue.3
, pp. 193-202
-
-
Eng, C.1
Kiuru, M.2
Fernandez, M.J.3
-
159
-
-
28544446058
-
Mitochondrial tumour suppressors: a genetic and biochemical update
-
Gottlieb E., and Tomlinson I.P. Mitochondrial tumour suppressors: a genetic and biochemical update. Nat Rev Cancer 5 11 (2005) 857-866
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.11
, pp. 857-866
-
-
Gottlieb, E.1
Tomlinson, I.P.2
-
160
-
-
0242320354
-
Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasia
-
Lima J., Teixeira-Gomes J., Soares P., et al. Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasia. J Clin Endocrinol Metab 88 10 (2003) 4932-4937
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.10
, pp. 4932-4937
-
-
Lima, J.1
Teixeira-Gomes, J.2
Soares, P.3
-
161
-
-
29144458355
-
No mutations but an increased frequency of SDHx polymorphisms in patients with sporadic and familial medullary thyroid carcinoma
-
Montani M., Schmitt A.M., Schmid S., et al. No mutations but an increased frequency of SDHx polymorphisms in patients with sporadic and familial medullary thyroid carcinoma. Endocr Relat Cancer 12 4 (2005) 1011-1016
-
(2005)
Endocr Relat Cancer
, vol.12
, Issue.4
, pp. 1011-1016
-
-
Montani, M.1
Schmitt, A.M.2
Schmid, S.3
-
162
-
-
20244385554
-
Succinate dehydrogenase D variants do not constitute a risk factor for developing C cell hyperplasia or sporadic medullary thyroid carcinoma
-
Cascon A., Cebrian A., Pollan M., et al. Succinate dehydrogenase D variants do not constitute a risk factor for developing C cell hyperplasia or sporadic medullary thyroid carcinoma. J Clin Endocrinol Metab 90 4 (2005) 2127-2130
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.4
, pp. 2127-2130
-
-
Cascon, A.1
Cebrian, A.2
Pollan, M.3
-
163
-
-
32244449268
-
Association of mitochondrial DNA transversion mutations with familial medullary thyroid carcinoma/multiple endocrine neoplasia type 2 syndrome
-
Abu-Amero K.K., Alzahrani A.S., Zou M., et al. Association of mitochondrial DNA transversion mutations with familial medullary thyroid carcinoma/multiple endocrine neoplasia type 2 syndrome. Oncogene 25 5 (2006) 677-684
-
(2006)
Oncogene
, vol.25
, Issue.5
, pp. 677-684
-
-
Abu-Amero, K.K.1
Alzahrani, A.S.2
Zou, M.3
-
164
-
-
0027215123
-
Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland
-
Donghi R., Longoni A., Pilotti S., et al. Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland. J Clin Invest 91 4 (1993) 1753-1760
-
(1993)
J Clin Invest
, vol.91
, Issue.4
, pp. 1753-1760
-
-
Donghi, R.1
Longoni, A.2
Pilotti, S.3
-
165
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
Fagin J.A., Matsuo K., Karmakar A., et al. High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 91 1 (1993) 179-184
-
(1993)
J Clin Invest
, vol.91
, Issue.1
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
-
166
-
-
0025865948
-
Mutation of the p53 gene in a differentiated human thyroid carcinoma cell line, but not in primary thyroid tumours
-
Wright P.A., Lemoine N.R., Goretzki P.E., et al. Mutation of the p53 gene in a differentiated human thyroid carcinoma cell line, but not in primary thyroid tumours. Oncogene 6 9 (1991) 1693-1697
-
(1991)
Oncogene
, vol.6
, Issue.9
, pp. 1693-1697
-
-
Wright, P.A.1
Lemoine, N.R.2
Goretzki, P.E.3
-
167
-
-
0026575904
-
Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland
-
Ito T., Seyama T., Mizuno T., et al. Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland. Cancer Res 52 5 (1992) 1369-1371
-
(1992)
Cancer Res
, vol.52
, Issue.5
, pp. 1369-1371
-
-
Ito, T.1
Seyama, T.2
Mizuno, T.3
-
168
-
-
0031783481
-
Prevalences of Gs alpha, ras, p53 mutations and ret/PTC rearrangement in differentiated thyroid tumours in a Korean population
-
Park K.Y., Koh J.M., Kim Y.I., et al. Prevalences of Gs alpha, ras, p53 mutations and ret/PTC rearrangement in differentiated thyroid tumours in a Korean population. Clin Endocrinol (Oxf) 49 3 (1998) 317-323
-
(1998)
Clin Endocrinol (Oxf)
, vol.49
, Issue.3
, pp. 317-323
-
-
Park, K.Y.1
Koh, J.M.2
Kim, Y.I.3
-
169
-
-
0027520294
-
p53 mutations in all stages of thyroid carcinomas
-
Zou M., Shi Y., and Farid N.R. p53 mutations in all stages of thyroid carcinomas. J Clin Endocrinol Metab 77 4 (1993) 1054-1058
-
(1993)
J Clin Endocrinol Metab
, vol.77
, Issue.4
, pp. 1054-1058
-
-
Zou, M.1
Shi, Y.2
Farid, N.R.3
-
170
-
-
0028214385
-
Immunohistochemical detection of p53 in differentiated, poorly differentiated and undifferentiated carcinomas of the thyroid
-
Soares P., Cameselle-Teijeiro J., and Sobrinho-Simões M. Immunohistochemical detection of p53 in differentiated, poorly differentiated and undifferentiated carcinomas of the thyroid. Histopathology 24 3 (1994) 205-210
-
(1994)
Histopathology
, vol.24
, Issue.3
, pp. 205-210
-
-
Soares, P.1
Cameselle-Teijeiro, J.2
Sobrinho-Simões, M.3
-
171
-
-
33845565405
-
Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression
-
[discussion: 905-6]
-
Saltman B., Singh B., Hedvat C.V., et al. Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression. Surgery 140 6 (2006) 899-905 [discussion: 905-6]
-
(2006)
Surgery
, vol.140
, Issue.6
, pp. 899-905
-
-
Saltman, B.1
Singh, B.2
Hedvat, C.V.3
-
172
-
-
0034103928
-
Molecular interactions in the Vogelstein model of colorectal carcinoma
-
Arends J.W. Molecular interactions in the Vogelstein model of colorectal carcinoma. J Pathol 190 4 (2000) 412-416
-
(2000)
J Pathol
, vol.190
, Issue.4
, pp. 412-416
-
-
Arends, J.W.1
-
173
-
-
0027189664
-
Genetic alterations in thyroid tumor progression: association with p53 gene mutations
-
Ito T., Seyama T., Mizuno T., et al. Genetic alterations in thyroid tumor progression: association with p53 gene mutations. Jpn J Cancer Res 84 5 (1993) 526-531
-
(1993)
Jpn J Cancer Res
, vol.84
, Issue.5
, pp. 526-531
-
-
Ito, T.1
Seyama, T.2
Mizuno, T.3
-
174
-
-
18844437226
-
Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations
-
Quiros R.M., Ding H.G., Gattuso P., et al. Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations. Cancer 103 11 (2005) 2261-2268
-
(2005)
Cancer
, vol.103
, Issue.11
, pp. 2261-2268
-
-
Quiros, R.M.1
Ding, H.G.2
Gattuso, P.3
-
175
-
-
85025576916
-
Origin and progression of thyroid epithelial tumours: cellular and molecular mechanisms
-
Wynford-Thomas D. Origin and progression of thyroid epithelial tumours: cellular and molecular mechanisms. Horm Res 47 4-6 (1997) 145-157
-
(1997)
Horm Res
, vol.47
, Issue.4-6
, pp. 145-157
-
-
Wynford-Thomas, D.1
-
176
-
-
0031815216
-
The influence of cell context on the selection pressure for p53 mutation in human cancer
-
Wynford-Thomas D., and Blaydes J. The influence of cell context on the selection pressure for p53 mutation in human cancer. Carcinogenesis 19 1 (1998) 29-36
-
(1998)
Carcinogenesis
, vol.19
, Issue.1
, pp. 29-36
-
-
Wynford-Thomas, D.1
Blaydes, J.2
-
177
-
-
0037364095
-
Anaplastic thyroid cancer: cytogenetic patterns by comparative genomic hybridization
-
Miura D., Wada N., Chin K., et al. Anaplastic thyroid cancer: cytogenetic patterns by comparative genomic hybridization. Thyroid 13 3 (2003) 283-290
-
(2003)
Thyroid
, vol.13
, Issue.3
, pp. 283-290
-
-
Miura, D.1
Wada, N.2
Chin, K.3
-
178
-
-
34247253321
-
Poorly differentiated and anaplastic thyroid carcinomas: chromosomal and oligo-array profile of five new cell lines
-
Rodrigues R.F., Roque L., Krug T., et al. Poorly differentiated and anaplastic thyroid carcinomas: chromosomal and oligo-array profile of five new cell lines. Br J Cancer 96 8 (2007) 1237-1245
-
(2007)
Br J Cancer
, vol.96
, Issue.8
, pp. 1237-1245
-
-
Rodrigues, R.F.1
Roque, L.2
Krug, T.3
-
179
-
-
0036841090
-
Genome-wide appraisal of thyroid cancer progression
-
Wreesmann V.B., Ghossein R.A., Patel S.G., et al. Genome-wide appraisal of thyroid cancer progression. Am J Pathol 161 5 (2002) 1549-1556
-
(2002)
Am J Pathol
, vol.161
, Issue.5
, pp. 1549-1556
-
-
Wreesmann, V.B.1
Ghossein, R.A.2
Patel, S.G.3
-
180
-
-
0034876933
-
Bcl2, p53 and bax in thyroid tumors and their relation to apoptosis
-
Farid P., Gomb S.Z., Peter I., et al. Bcl2, p53 and bax in thyroid tumors and their relation to apoptosis. Neoplasma 48 4 (2001) 299-301
-
(2001)
Neoplasma
, vol.48
, Issue.4
, pp. 299-301
-
-
Farid, P.1
Gomb, S.Z.2
Peter, I.3
-
181
-
-
0035877135
-
Bax expression in benign and malignant thyroid tumours: dysregulation of wild-type P53 is associated with a high Bax and P21 expression in thyroid carcinoma
-
Hermann S., Sturm I., Mrozek A., et al. Bax expression in benign and malignant thyroid tumours: dysregulation of wild-type P53 is associated with a high Bax and P21 expression in thyroid carcinoma. Int J Cancer 92 6 (2001) 805-811
-
(2001)
Int J Cancer
, vol.92
, Issue.6
, pp. 805-811
-
-
Hermann, S.1
Sturm, I.2
Mrozek, A.3
-
182
-
-
0031912856
-
Apoptosis in thyroid neoplasms: relationship with p53 and bcl-2 expression
-
Moore D., Ohene-Fianko D., Garcia B., et al. Apoptosis in thyroid neoplasms: relationship with p53 and bcl-2 expression. Histopathology 32 1 (1998) 35-42
-
(1998)
Histopathology
, vol.32
, Issue.1
, pp. 35-42
-
-
Moore, D.1
Ohene-Fianko, D.2
Garcia, B.3
-
183
-
-
0033561515
-
Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma
-
Garcia-Rostan G., Tallini G., Herrero A., et al. Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma. Cancer Res 59 8 (1999) 1811-1815
-
(1999)
Cancer Res
, vol.59
, Issue.8
, pp. 1811-1815
-
-
Garcia-Rostan, G.1
Tallini, G.2
Herrero, A.3
-
184
-
-
0030045908
-
Infrequent CDKN2 mutation in human differentiated thyroid cancers
-
Tung W.S., Shevlin D.W., Bartsch D., et al. Infrequent CDKN2 mutation in human differentiated thyroid cancers. Mol Carcinog 15 1 (1996) 5-10
-
(1996)
Mol Carcinog
, vol.15
, Issue.1
, pp. 5-10
-
-
Tung, W.S.1
Shevlin, D.W.2
Bartsch, D.3
-
185
-
-
0033951970
-
N-ras mutation in poorly differentiated thyroid carcinomas: correlation with bone metastases and inverse correlation to thyroglobulin expression
-
Basolo F., Pisaturo F., Pollina L.E., et al. N-ras mutation in poorly differentiated thyroid carcinomas: correlation with bone metastases and inverse correlation to thyroglobulin expression. Thyroid 10 1 (2000) 19-23
-
(2000)
Thyroid
, vol.10
, Issue.1
, pp. 19-23
-
-
Basolo, F.1
Pisaturo, F.2
Pollina, L.E.3
-
186
-
-
0028030757
-
Selective activation of ras oncogenes in follicular and undifferentiated thyroid carcinomas
-
Manenti G., Pilotti S., Re F.C., et al. Selective activation of ras oncogenes in follicular and undifferentiated thyroid carcinomas. Eur J Cancer 30A 7 (1994) 987-993
-
(1994)
Eur J Cancer
, vol.30 A
, Issue.7
, pp. 987-993
-
-
Manenti, G.1
Pilotti, S.2
Re, F.C.3
-
187
-
-
0142135475
-
BRAF mutations in papillary carcinomas of the thyroid
-
Fukushima T., Suzuki S., Mashiko M., et al. BRAF mutations in papillary carcinomas of the thyroid. Oncogene 22 41 (2003) 6455-6457
-
(2003)
Oncogene
, vol.22
, Issue.41
, pp. 6455-6457
-
-
Fukushima, T.1
Suzuki, S.2
Mashiko, M.3
-
188
-
-
0141465066
-
Ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer
-
Garcia-Rostan G., Zhao H., Camp R.L., et al. Ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer. J Clin Oncol 21 17 (2003) 3226-3235
-
(2003)
J Clin Oncol
, vol.21
, Issue.17
, pp. 3226-3235
-
-
Garcia-Rostan, G.1
Zhao, H.2
Camp, R.L.3
-
189
-
-
34347251976
-
High prevalence and mutual exclusivity of genetic alterations in the phosphatidylinositol-3-kinase/akt pathway in thyroid tumors
-
Wang Y., Hou P., Yu H., et al. High prevalence and mutual exclusivity of genetic alterations in the phosphatidylinositol-3-kinase/akt pathway in thyroid tumors. J Clin Endocrinol Metab 92 6 (2007) 2387-2390
-
(2007)
J Clin Endocrinol Metab
, vol.92
, Issue.6
, pp. 2387-2390
-
-
Wang, Y.1
Hou, P.2
Yu, H.3
-
190
-
-
33947284529
-
Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer
-
Hou P., Liu D., Shan Y., et al. Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer. Clin Cancer Res 13 4 (2007) 1161-1170
-
(2007)
Clin Cancer Res
, vol.13
, Issue.4
, pp. 1161-1170
-
-
Hou, P.1
Liu, D.2
Shan, Y.3
-
191
-
-
0035108299
-
Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis
-
Garcia-Rostan G., Camp R.L., Herrero A., et al. Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis. Am J Pathol 158 3 (2001) 987-996
-
(2001)
Am J Pathol
, vol.158
, Issue.3
, pp. 987-996
-
-
Garcia-Rostan, G.1
Camp, R.L.2
Herrero, A.3
-
192
-
-
34247357463
-
Overexpression of Wnt-1 in thyrocytes enhances cellular growth but suppresses transcription of the thyroperoxidase gene via different signaling mechanisms
-
Kim W.B., Lewis C.J., McCall K.D., et al. Overexpression of Wnt-1 in thyrocytes enhances cellular growth but suppresses transcription of the thyroperoxidase gene via different signaling mechanisms. J Endocrinol 193 1 (2007) 93-106
-
(2007)
J Endocrinol
, vol.193
, Issue.1
, pp. 93-106
-
-
Kim, W.B.1
Lewis, C.J.2
McCall, K.D.3
-
193
-
-
0038170599
-
E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas
-
Rocha A.S., Soares P., Fonseca E., et al. E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas. Histopathology 42 6 (2003) 580-587
-
(2003)
Histopathology
, vol.42
, Issue.6
, pp. 580-587
-
-
Rocha, A.S.1
Soares, P.2
Fonseca, E.3
-
194
-
-
19944426556
-
Immunohistochemical and sequencing analyses of the Wnt signaling components in Japanese anaplastic thyroid cancers
-
Kurihara T., Ikeda S., Ishizaki Y., et al. Immunohistochemical and sequencing analyses of the Wnt signaling components in Japanese anaplastic thyroid cancers. Thyroid 14 12 (2004) 1020-1029
-
(2004)
Thyroid
, vol.14
, Issue.12
, pp. 1020-1029
-
-
Kurihara, T.1
Ikeda, S.2
Ishizaki, Y.3
-
195
-
-
0036084567
-
Poorly differentiated carcinomas of the thyroid gland: a review of the clinicopathologic features of a series of 28 cases of a heterogeneous, clinically aggressive group of thyroid tumors
-
Sobrinho-Simões M., Sambade C., Fonseca E., et al. Poorly differentiated carcinomas of the thyroid gland: a review of the clinicopathologic features of a series of 28 cases of a heterogeneous, clinically aggressive group of thyroid tumors. Int J Surg Pathol 10 2 (2002) 123-131
-
(2002)
Int J Surg Pathol
, vol.10
, Issue.2
, pp. 123-131
-
-
Sobrinho-Simões, M.1
Sambade, C.2
Fonseca, E.3
-
196
-
-
0035057361
-
Somatic but not germline mutation of the APC gene in a case of cribriform-morular variant of papillary thyroid carcinoma
-
Cameselle-Teijeiro J., Ruiz-Ponte C., Loidi L., et al. Somatic but not germline mutation of the APC gene in a case of cribriform-morular variant of papillary thyroid carcinoma. Am J Clin Pathol 115 4 (2001) 486-493
-
(2001)
Am J Clin Pathol
, vol.115
, Issue.4
, pp. 486-493
-
-
Cameselle-Teijeiro, J.1
Ruiz-Ponte, C.2
Loidi, L.3
-
197
-
-
0032908038
-
Cribriform-morular variant of papillary carcinoma: a distinctive variant representing the sporadic counterpart of familial adenomatous polyposis-associated thyroid carcinoma?
-
Cameselle-Teijeiro J., and Chan J.K. Cribriform-morular variant of papillary carcinoma: a distinctive variant representing the sporadic counterpart of familial adenomatous polyposis-associated thyroid carcinoma?. Mod Pathol 12 4 (1999) 400-411
-
(1999)
Mod Pathol
, vol.12
, Issue.4
, pp. 400-411
-
-
Cameselle-Teijeiro, J.1
Chan, J.K.2
-
198
-
-
3042806973
-
BRAF mutations typical of papillary thyroid carcinoma are more frequently detected in undifferentiated than in insular and insular-like poorly differentiated carcinomas
-
Soares P., Trovisco V., Rocha A.S., et al. BRAF mutations typical of papillary thyroid carcinoma are more frequently detected in undifferentiated than in insular and insular-like poorly differentiated carcinomas. Virchows Arch 444 6 (2004) 572-576
-
(2004)
Virchows Arch
, vol.444
, Issue.6
, pp. 572-576
-
-
Soares, P.1
Trovisco, V.2
Rocha, A.S.3
-
200
-
-
0028038994
-
Papillary and follicular thyroid carcinomas with an insular component
-
Ashfaq R., Vuitch F., Delgado R., et al. Papillary and follicular thyroid carcinomas with an insular component. Cancer 73 2 (1994) 416-423
-
(1994)
Cancer
, vol.73
, Issue.2
, pp. 416-423
-
-
Ashfaq, R.1
Vuitch, F.2
Delgado, R.3
-
201
-
-
0021165886
-
Poorly differentiated ("insular") thyroid carcinoma. A reinterpretation of Langhans' "wuchernde Struma"
-
Carcangiu M.L., Zampi G., and Rosai J. Poorly differentiated ("insular") thyroid carcinoma. A reinterpretation of Langhans' "wuchernde Struma". Am J Surg Pathol 8 9 (1984) 655-668
-
(1984)
Am J Surg Pathol
, vol.8
, Issue.9
, pp. 655-668
-
-
Carcangiu, M.L.1
Zampi, G.2
Rosai, J.3
-
202
-
-
0027522721
-
Poorly differentiated thyroid carcinomas with primordial cell component. A group of aggressive lesions sharing insular, trabecular, and solid patterns
-
Papotti M., Botto Micca F., Favero A., et al. Poorly differentiated thyroid carcinomas with primordial cell component. A group of aggressive lesions sharing insular, trabecular, and solid patterns. Am J Surg Pathol 17 3 (1993) 291-301
-
(1993)
Am J Surg Pathol
, vol.17
, Issue.3
, pp. 291-301
-
-
Papotti, M.1
Botto Micca, F.2
Favero, A.3
-
203
-
-
34248581994
-
BRAF V600E mutation in anaplastic thyroid carcinomas and their accompanying differentiated carcinomas
-
Takano T., Ito Y., Hirokawa M., et al. BRAF V600E mutation in anaplastic thyroid carcinomas and their accompanying differentiated carcinomas. Br J Cancer 96 10 (2007) 1549-1553
-
(2007)
Br J Cancer
, vol.96
, Issue.10
, pp. 1549-1553
-
-
Takano, T.1
Ito, Y.2
Hirokawa, M.3
-
204
-
-
0031933680
-
RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes
-
Tallini G., Santoro M., Helie M., et al. RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes. Clin Cancer Res 4 2 (1998) 287-294
-
(1998)
Clin Cancer Res
, vol.4
, Issue.2
, pp. 287-294
-
-
Tallini, G.1
Santoro, M.2
Helie, M.3
-
205
-
-
23844446683
-
Uncommon mutation, but common amplifications, of the PIK3CA gene in thyroid tumors
-
Wu G., Mambo E., Guo Z., et al. Uncommon mutation, but common amplifications, of the PIK3CA gene in thyroid tumors. J Clin Endocrinol Metab 90 8 (2005) 4688-4693
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.8
, pp. 4688-4693
-
-
Wu, G.1
Mambo, E.2
Guo, Z.3
-
206
-
-
28544452359
-
Mutation of the PIK3CA gene in anaplastic thyroid cancer
-
Garcia-Rostan G., Costa A.M., Pereira-Castro I., et al. Mutation of the PIK3CA gene in anaplastic thyroid cancer. Cancer Res 65 22 (2005) 10199-10207
-
(2005)
Cancer Res
, vol.65
, Issue.22
, pp. 10199-10207
-
-
Garcia-Rostan, G.1
Costa, A.M.2
Pereira-Castro, I.3
-
207
-
-
24344485471
-
Letter re: uncommon mutation but common amplifications of the PIK3CA gene in thyroid tumors
-
Liu D., Mambo E., Ladenson P.W., et al. Letter re: uncommon mutation but common amplifications of the PIK3CA gene in thyroid tumors. J Clin Endocrinol Metab 90 9 (2005) 5509
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.9
, pp. 5509
-
-
Liu, D.1
Mambo, E.2
Ladenson, P.W.3
-
208
-
-
18244390747
-
RET activation and clinicopathologic features in poorly differentiated thyroid tumors
-
Santoro M., Papotti M., Chiappetta G., et al. RET activation and clinicopathologic features in poorly differentiated thyroid tumors. J Clin Endocrinol Metab 87 1 (2002) 370-379
-
(2002)
J Clin Endocrinol Metab
, vol.87
, Issue.1
, pp. 370-379
-
-
Santoro, M.1
Papotti, M.2
Chiappetta, G.3
-
209
-
-
0141564533
-
Involvement of the PAX8/peroxisome proliferator-activated receptor gamma rearrangement in follicular thyroid tumors
-
Dwight T., Thoppe S.R., Foukakis T., et al. Involvement of the PAX8/peroxisome proliferator-activated receptor gamma rearrangement in follicular thyroid tumors. J Clin Endocrinol Metab 88 9 (2003) 4440-4445
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.9
, pp. 4440-4445
-
-
Dwight, T.1
Thoppe, S.R.2
Foukakis, T.3
-
210
-
-
33947135790
-
RET oncogene amplification in thyroid cancer: correlations with radiation-associated and high-grade malignancy
-
Nakashima M., Takamura N., Namba H., et al. RET oncogene amplification in thyroid cancer: correlations with radiation-associated and high-grade malignancy. Hum Pathol 38 4 (2007) 621-628
-
(2007)
Hum Pathol
, vol.38
, Issue.4
, pp. 621-628
-
-
Nakashima, M.1
Takamura, N.2
Namba, H.3
-
211
-
-
0029093051
-
Rarity of oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in Japan
-
Takeshita A., Nagayama Y., Yokoyama N., et al. Rarity of oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in Japan. J Clin Endocrinol Metab 80 9 (1995) 2607-2611
-
(1995)
J Clin Endocrinol Metab
, vol.80
, Issue.9
, pp. 2607-2611
-
-
Takeshita, A.1
Nagayama, Y.2
Yokoyama, N.3
-
212
-
-
0029782050
-
Low incidence of the stimulatory G protein alpha-subunit mutations in autonomously functioning thyroid adenomas in Japan
-
Tanaka K., Nagayama Y., Takeshita A., et al. Low incidence of the stimulatory G protein alpha-subunit mutations in autonomously functioning thyroid adenomas in Japan. Thyroid 6 3 (1996) 195-199
-
(1996)
Thyroid
, vol.6
, Issue.3
, pp. 195-199
-
-
Tanaka, K.1
Nagayama, Y.2
Takeshita, A.3
-
213
-
-
0030215518
-
TSH receptor and Gs-alpha gene mutations in the pathogenesis of toxic thyroid adenomas-a note of caution
-
Derwahl M. TSH receptor and Gs-alpha gene mutations in the pathogenesis of toxic thyroid adenomas-a note of caution. J Clin Endocrinol Metab 81 8 (1996) 2783-2785
-
(1996)
J Clin Endocrinol Metab
, vol.81
, Issue.8
, pp. 2783-2785
-
-
Derwahl, M.1
-
214
-
-
8544221172
-
Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas
-
Parma J., Duprez L., Van Sande J., et al. Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas. J Clin Endocrinol Metab 82 8 (1997) 2695-2701
-
(1997)
J Clin Endocrinol Metab
, vol.82
, Issue.8
, pp. 2695-2701
-
-
Parma, J.1
Duprez, L.2
Van Sande, J.3
-
215
-
-
0030724982
-
New pathophysiological mechanisms for hyperthyroidism
-
Vassart G. New pathophysiological mechanisms for hyperthyroidism. Horm Res 48 Suppl 4 (1997) 47-50
-
(1997)
Horm Res
, vol.48
, Issue.SUPPL. 4
, pp. 47-50
-
-
Vassart, G.1
-
216
-
-
0030710212
-
Somatic mutations in the thyrotropin receptor gene and not in the Gs alpha protein gene in 31 toxic thyroid nodules
-
Führer D., Holzapfel H.P., Wonerow P., et al. Somatic mutations in the thyrotropin receptor gene and not in the Gs alpha protein gene in 31 toxic thyroid nodules. J Clin Endocrinol Metab 82 11 (1997) 3885-3891
-
(1997)
J Clin Endocrinol Metab
, vol.82
, Issue.11
, pp. 3885-3891
-
-
Führer, D.1
Holzapfel, H.P.2
Wonerow, P.3
-
217
-
-
0031773273
-
The extracellular thyrotropin receptor domain is not a major candidate for mutations in toxic thyroid nodules
-
Führer D., Kubisch C., Scheibler U., et al. The extracellular thyrotropin receptor domain is not a major candidate for mutations in toxic thyroid nodules. Thyroid 8 11 (1998) 997-1001
-
(1998)
Thyroid
, vol.8
, Issue.11
, pp. 997-1001
-
-
Führer, D.1
Kubisch, C.2
Scheibler, U.3
-
218
-
-
17744383626
-
Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter
-
Tonacchera M., Agretti P., Chiovato L., et al. Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter. J Clin Endocrinol Metab 85 6 (2000) 2270-2274
-
(2000)
J Clin Endocrinol Metab
, vol.85
, Issue.6
, pp. 2270-2274
-
-
Tonacchera, M.1
Agretti, P.2
Chiovato, L.3
-
219
-
-
0034828723
-
Ras mutations are rare in solitary cold and toxic thyroid nodules
-
Krohn K., Reske A., Ackermann F., et al. Ras mutations are rare in solitary cold and toxic thyroid nodules. Clin Endocrinol (Oxf) 55 2 (2001) 241-248
-
(2001)
Clin Endocrinol (Oxf)
, vol.55
, Issue.2
, pp. 241-248
-
-
Krohn, K.1
Reske, A.2
Ackermann, F.3
-
220
-
-
0028927822
-
Genetic alterations in thyroid hyperfunctioning adenomas
-
Russo D., Arturi F., Wicker R., et al. Genetic alterations in thyroid hyperfunctioning adenomas. J Clin Endocrinol Metab 80 4 (1995) 1347-1351
-
(1995)
J Clin Endocrinol Metab
, vol.80
, Issue.4
, pp. 1347-1351
-
-
Russo, D.1
Arturi, F.2
Wicker, R.3
-
221
-
-
0031059155
-
Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma
-
Russo D., Tumino S., Arturi F., et al. Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma. J Clin Endocrinol Metab 82 3 (1997) 735-738
-
(1997)
J Clin Endocrinol Metab
, vol.82
, Issue.3
, pp. 735-738
-
-
Russo, D.1
Tumino, S.2
Arturi, F.3
-
222
-
-
0033775588
-
No evidence of thyrotropin receptor and Gs(alpha) gene mutation in high iodine uptake thyroid carcinoma
-
Bourasseau I., Savagner F., Rodien P., et al. No evidence of thyrotropin receptor and Gs(alpha) gene mutation in high iodine uptake thyroid carcinoma. Thyroid 10 9 (2000) 761-765
-
(2000)
Thyroid
, vol.10
, Issue.9
, pp. 761-765
-
-
Bourasseau, I.1
Savagner, F.2
Rodien, P.3
-
223
-
-
0347717977
-
Two somatic TSH receptor mutations in a patient with toxic metastasising follicular thyroid carcinoma and non-functional lung metastases
-
Führer D., Tannapfel A., Sabri O., et al. Two somatic TSH receptor mutations in a patient with toxic metastasising follicular thyroid carcinoma and non-functional lung metastases. Endocr Relat Cancer 10 4 (2003) 591-600
-
(2003)
Endocr Relat Cancer
, vol.10
, Issue.4
, pp. 591-600
-
-
Führer, D.1
Tannapfel, A.2
Sabri, O.3
-
224
-
-
0027407475
-
Overexpression of p53 as a possible prognostic factor in human thyroid carcinoma
-
Dobashi Y., Sakamoto A., Sugimura H., et al. Overexpression of p53 as a possible prognostic factor in human thyroid carcinoma. Am J Surg Pathol 17 4 (1993) 375-381
-
(1993)
Am J Surg Pathol
, vol.17
, Issue.4
, pp. 375-381
-
-
Dobashi, Y.1
Sakamoto, A.2
Sugimura, H.3
-
225
-
-
0029867407
-
p53 gene mutation in thyroid carcinoma
-
Ho Y.S., Tseng S.C., Chin T.Y., et al. p53 gene mutation in thyroid carcinoma. Cancer Lett 103 1 (1996) 57-63
-
(1996)
Cancer Lett
, vol.103
, Issue.1
, pp. 57-63
-
-
Ho, Y.S.1
Tseng, S.C.2
Chin, T.Y.3
-
226
-
-
0032968315
-
Mutations of p53 in thyroid carcinoma with an insular component
-
Takeuchi Y., Daa T., Kashima K., et al. Mutations of p53 in thyroid carcinoma with an insular component. Thyroid 9 4 (1999) 377-381
-
(1999)
Thyroid
, vol.9
, Issue.4
, pp. 377-381
-
-
Takeuchi, Y.1
Daa, T.2
Kashima, K.3
-
227
-
-
0030024078
-
Ras oncogene mutations in thyroid tumors: polymerase chain reaction-restriction-fragment-length polymorphism analysis from paraffin-embedded tissues
-
Capella G., Matias-Guiu X., Ampudia X., et al. Ras oncogene mutations in thyroid tumors: polymerase chain reaction-restriction-fragment-length polymorphism analysis from paraffin-embedded tissues. Diagn Mol Pathol 5 1 (1996) 45-52
-
(1996)
Diagn Mol Pathol
, vol.5
, Issue.1
, pp. 45-52
-
-
Capella, G.1
Matias-Guiu, X.2
Ampudia, X.3
-
228
-
-
0030700727
-
Insular carcinoma: a distinct de novo entity among follicular carcinomas of the thyroid gland
-
Pilotti S., Collini P., Mariani L., et al. Insular carcinoma: a distinct de novo entity among follicular carcinomas of the thyroid gland. Am J Surg Pathol 21 12 (1997) 1466-1473
-
(1997)
Am J Surg Pathol
, vol.21
, Issue.12
, pp. 1466-1473
-
-
Pilotti, S.1
Collini, P.2
Mariani, L.3
-
229
-
-
33645964665
-
Roles of RAS and BRAF mutations in thyroid carcinogenesis
-
Fukushima T., and Takenoshita S. Roles of RAS and BRAF mutations in thyroid carcinogenesis. Fukushima J Med Sci 51 2 (2005) 67-75
-
(2005)
Fukushima J Med Sci
, vol.51
, Issue.2
, pp. 67-75
-
-
Fukushima, T.1
Takenoshita, S.2
|