BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: Functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis

Endocrinology

Volumn 147, Issue 2, 2006, Pages 1014-1019

  Mitsutake, Norisato ^a   Miyagishi, Makoto ^b   Mitsutake, Shin ^a   Akeno, Nagako ^a   Mesa Jr , Cleo ^a   Knauf, Jeffrey A ^a   Zhang, Lei ^a   Taira, Kazunari ^b   Fagin, James A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; DOXYCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN RET; RAF PROTEIN; RAS PROTEIN; SMALL INTERFERING RNA; SODIUM IODIDE SYMPORTER;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL LINE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE CONTROL; GENE REARRANGEMENT; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA VECTOR; SIGNAL TRANSDUCTION; THYROID CANCER; THYROID CELL;

ANIMALS; CARCINOMA, PAPILLARY; CELLS, CULTURED; CLONE CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; ISOENZYMES; ONCOGENE PROTEINS, FUSION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF; PROTO-ONCOGENE PROTEINS C-RET; RATS; RNA; THYROID GLAND; THYROID NEOPLASMS;

EID: 30944445020     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-0280     Document Type: Article

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