Poorly differentiated and anaplastic thyroid carcinomas: Chromosomal and oligo-array profile of five new cell lines

British Journal of Cancer

Volumn 96, Issue 8, 2007, Pages 1237-1245

  Rodrigues, R F ^a   Roque, L ^a   Krug, T ^b   Leite, V ^a  

^a Portuguese Cancer Institute   (Portugal)

^b Gene Express Lda   (Portugal)

Author keywords

CGH; Expression; Profile; Thyroid

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; UVOMORULIN;

ADULT; AGED; AMPLICON; ANAPLASTIC CARCINOMA; ARTICLE; CANCER CELL CULTURE; CELL ADHESION; CELL MOTILITY; CELL TYPE; CHROMOSOME ANALYSIS; DOWN REGULATION; FEMALE; GENE AMPLIFICATION; GENE TARGETING; HUMAN; HUMAN CELL; MALE; MICROARRAY ANALYSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYROID CARCINOMA; TUMOR DIFFERENTIATION;

AGED; CELL LINE, TUMOR; CHROMOSOME ABERRATIONS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; THYROID NEOPLASMS;

EID: 34247253321     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603578     Document Type: Article

References (35)

1. Abe Y, Matsumuto S, Kito K, Ueda N (2000) Cloning and expression of a novel MAPKK-like protein kinase, lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cells. J Biol Chem 275: 21525-21531
2. Adams RR, Carmena M, Earnshaw WC (2001) Chromosomal passengers and the (aurora) ABCs of mitosis. Trends Cell Biol 11: 49-54
3. Asakawa H, Kobayashi T, Komoike Y, Yanagawa T, Takahashi M, Wakasugi E, Maruyama H, Tamaki Y, Matsuzawa Y, Moden M (1996) Establishment of anaplastic thyroid carcinoma cell lines useful for analysis of chemosensivity and cancerigenesis. J Clin Endocrinol Metab 81: 3547-3552
4. Brodeur GM (2003) Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3: 203-216
5. DeLellis RA, Williams ED (2004) Tumors of the thyroid and parathyroid. In World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of Endocrine Organs DeLellis RA, Lloyd RV, Heitz PU, Eng C (eds) pp 49-93. Lyon: IARC Press
6. Elisei R, Pinchera A, Romei C, Gryczynska M, Pohl V, Maenhaut C, Fugazzola L, Pacini F (1994) Expression of thyrotropin receptor (TSH-R), thyroglobulin, thyroperoxidase, and calcitonin messenger ribonucleic acids in thyroid carcinomas: evidence of TSH-R gene transcript in medullary histotype. J Clin Endocrinol Metab 78: 867-871
7. Garcia-Rostan G, Tallini G, Herrero A, D'Aquila TG, Carcangiu ML, Rimm DL (1999) Frequent mutation and nuclear localization of β-catenin in anaplastic thyroid carcinoma. Cancer Res 59: 1811-1815
8. Guo Y, Mazar AP, Lebrun JJ, Rabbani SA (2002) An antiangiogenic urokinase-derived peptide combined with tamoxifen decreases tumor growth and metastasis in a syngeneic model of breast cancer. Cancer Res 62: 4678-4684
9. Hemmer S, Wasenius VM, Knuutila S, Franssila K, Joensuu H (1999) DNA copy number changes in thyroid carcinoma. Am J Pathol 154: 1539-1547
10. Hochhaus A (2004) Imabitinib mesylate (Glivec, Gleevec) in the treatment of chronic myelogenous leukaemia (CML) and gastrointestinal stromal tumors (GIST). Ann Hematol 83(Suppl 1): S65-S66
11. Hosoda K, Nakao K, Tamura N, Arai H, Ogawa Y, Suga S, Nakanishi S, Imura H (1992) Organization, structure, chromosomal assignment, and expression of the gene encoding the human endothelin-A receptor. J Biol Chem 26: 18797-18804
12. Katoh M, Katoh M (2003) CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family. Int J Mol Med 11: 683-689
13. Kim JY, Ahn HJ, Ryu JH, Suk K, Park JH (2004) BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1 alpha. J Exp Med 199: 113-124
14. Kitamura Y, Shimizu K, Ito K, Tanaka S, Emi M (2001) Allelotyping of follicular thyroid carcinoma: frequent allelic losses in chromosome arms 7q, 11p, and 22q. J Clin Endocrinol Metab 86: 4268-4272
15. Kotani M, Detheux M, Vandenbogaerde A, Communi D, Vanderwinden JM, Le Poul E, Brezillon S, Tyldesley R, Suarez-Huerta N, Vandeput F, Blanpain C, Schiffmann SN, Vassart G, Parmentier M (2001) The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein- coupled receptor GPR54. J Biol Chem 276: 34631-34636
16. Lacroix L, Lazar V, Michiels S, Ripoche H, Dessen P, Talbot M, Caillou B, Levillain JP, Schlumberger M, Bidart JM (2005) Follicular thyroid tumors with the PAX8-PPARγ1 rearrangement display characteristic genetic alterations. Am J Pathol 167: 223-231
17. Mellilo RM, Castellone MD, Guarino V, De Falco V, Cirafici AM, Salvatore G, Caiazzo F, Basolo F, Giannini R, Kruhoffer M, Orntoft T, Fusco A, Santoro M (2005) The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenothype of thyroid cancer cells. J Clin Invest 115: 1068-1081
18. Mitelman F (1995) ISCN. An Iternational System for Human Cytogenetic Nomenclature. Switzerland: Karger Landers, Basel.
19. Mizutani K, Onda M, Asaka S, Akaishi J, Miyamoto S, Yoshida A, Nagahama M, Ito K, Emi M (2005) Overexpressed in anaplastic thyroid carcinoma-1 (OEATC-1) as a novel gene responsible for anaplastic thyroid carcinoma. Cancer 103: 1785-1790
20. Onda M, Emi M, Yoshida A, Miyamoto S, Akaishi J, Asaka S, Mizutani K, Shimizu K, Nagahama M, Ito K, Tanaka T, Tsunoda T (2004) Comprehensive gene expression profiling of anaplastic thyroid cancers with cDNA microarrays of 25 344 genes. Endocr-Relat Cancer 11: 843-854
21. Platzer P, Upender MB, Wilson K, Willis J, Lutterbaugh J, Nosrati A, Willson Jk, Mack D, Ried T, Markowitz S (2002) Silence of chromosomal amplifications in colon cancer. Cancer Res 62: 1134-1138
22. Ringel MD, Greenberg M, Chen X, Hayre N, Suzuki K, Priebat D, Saji M, Burman KD (2000) Cytotoxic activity of 2',2'- difluorodeoxycytine (gemcitabine) in poorly differentiated thyroid carcinoma cells. Thyroid 10: 865-869
23. Rocha AS, Soares P, Fonseca E, Cameselle-Teijeiro J, Oliveira MC, Sobrinho-Simões M (2003) E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas. Histopathology 42: 580-587
24. Rodrigues RF, Roque L, Rosa-Santos J, Cid O, Soares J (2004) Chromosomal imbalances associated with anaplastic transformation of follicular thyroid carcinomas. Br J Cancer 90: 492-496
25. Roque L, Soares J, Castedo S (1998) Cytogenetic and fluorescence in situ hybridization studies in a case of anaplastic thyroid carinoma. Cancer Genet Cytogenet 103: 7-10
26. Roque L, Nunes VM, Ribeiro C, Martins C, Soares J (2001) Karyotypic characterization of papillary thyroid carcinomas. Cancer 92: 2529-2538
27. Rosai J, Carcangiu ML, DeLellis R (1992) Tumors of the Thyroid Gland. Atlas of Tumor Pathology 3rd Series. Washington, DC: Armed Forces Institute of Pathology.
28. Shintani S, Ishikawa T, Nonaka T, Li C, Nakashiro K, Wong DT, Hamakawa H (2004) Growth-regulated oncogene-1 expression is associated with angiogenesis and lymph node metastasis in human oral cancer. Oncology 66: 316-322
29. Sorrentino R, Libertini S, Pallante PL, Troncone G, Palombini L, Bavetsias V, Spalletti-Cernia D, Laccetti P, Linardopoulos S, Chieffi P, Fusco A, Portella G (2005) Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation. J Clin Endocrinol Metab 90: 928-935
30. Vogelstein B, Kinzler KW (1998) The Genetic Basis of Human Cancer. USA: McGraw-Hill Companies Inc.
31. Wilkens L, Benten D, Tchinda J, Brabant G, Potter E, Dralle H, von Wasielewski R (2000) Aberrations of chromosome 5 and 8 as recurrent cytogenetic events in anaplastic carcinoma of the thyroid as detected by fluorescence in situ hybridization and comparative genomic hybridization. Virchows Arch 436: 312-318
32. Wreesmann VB, Ghossein RA, Patel, SG, Harris CP, Schnaser EA, Shaha AR, Tuttle RM, Shah JP, Rao, PH, Singh B (2002) Genome-wide appraisal of thyroid cancer progression. Am J Pathol 161: 1549-1556
33. Wynford-Thomas D (1997) Origin and progression of thyroid epithelial tumours: cellular and molecular mechanisms. Horm Res 47: 145-157
34. Yakovlev AG, Di Giovanni S, Wang G, Liu W, Stoica B, Faden AI (2004) BOK and NOXA are essential mediators of p53-dependent apoptosis. J Biol Chem 279: 28367-28374
35. Zenklusen JC, Conti CJ, Green ED (2001) Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31. Nat Genet 27: 392-398