-
1
-
-
0028825189
-
RET/PTC oncogene activation is an early event in thyroid carcinogenesis
-
Viglietto, G., Chiappetta, G., Martinez-Tello, F. J., Fukunaga, F. H., Tallini, G., Rigopoulou, D., Visconti, R., Mastro, A., Santoro, M., and Fusco, A. RET/PTC oncogene activation is an early event in thyroid carcinogenesis. Oncogene, 11: 1207-1210, 1995.
-
(1995)
Oncogene
, vol.11
, pp. 1207-1210
-
-
Viglietto, G.1
Chiappetta, G.2
Martinez-Tello, F.J.3
Fukunaga, F.H.4
Tallini, G.5
Rigopoulou, D.6
Visconti, R.7
Mastro, A.8
Santoro, M.9
Fusco, A.10
-
2
-
-
0028821932
-
Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident
-
Fugazzola, L., Pilotti, S., Pinchera, A., Vorontsova, T. V., Mondellini, P., Bongarzone, I., Greco, A., Astakhova, L., Butti, M. G., Demidchik, E. P., and et al. Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident. Cancer Res., 55: 5617-5620, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 5617-5620
-
-
Fugazzola, L.1
Pilotti, S.2
Pinchera, A.3
Vorontsova, T.V.4
Mondellini, P.5
Bongarzone, I.6
Greco, A.7
Astakhova, L.8
Butti, M.G.9
Demidchik, E.P.10
-
3
-
-
0030941779
-
Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children
-
Nikiforov, Y. E., Rowland, J. M., Bove, K. E., Monforte-Munoz, H., and Fagin, J. A. Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children. Cancer Res., 57: 1690-1694, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 1690-1694
-
-
Nikiforov, Y.E.1
Rowland, J.M.2
Bove, K.E.3
Monforte-Munoz, H.4
Fagin, J.A.5
-
4
-
-
0030929178
-
High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation
-
Bounacer, A., Wicker, R., Caillou, B., Cailleux, A. F., Sarasin, A., Schlumberger, M., and Suarez, H. G. High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation. Oncogene, 15: 1263-1273, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 1263-1273
-
-
Bounacer, A.1
Wicker, R.2
Caillou, B.3
Cailleux, A.F.4
Sarasin, A.5
Schlumberger, M.6
Suarez, H.G.7
-
5
-
-
6244280442
-
High prevalence of RET rearrangement in thyroid tumors of children from Belarus after the Chernobyl reactor accident
-
Klugbauer, S., Lengfelder, E., Demidchik, E. P., and Rabes, H. M. High prevalence of RET rearrangement in thyroid tumors of children from Belarus after the Chernobyl reactor accident. Oncogene, 11: 2459-2467, 1995.
-
(1995)
Oncogene
, vol.11
, pp. 2459-2467
-
-
Klugbauer, S.1
Lengfelder, E.2
Demidchik, E.P.3
Rabes, H.M.4
-
6
-
-
0034613291
-
Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells
-
Nikiforova, M. N., Stringer, J. R., Blough, R., Medvedovic, M., Fagin, J. A., and Nikiforov, Y. E. Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. Science (Wash. DC), 290: 138-141, 2000.
-
(2000)
Science (Wash. DC)
, vol.290
, pp. 138-141
-
-
Nikiforova, M.N.1
Stringer, J.R.2
Blough, R.3
Medvedovic, M.4
Fagin, J.A.5
Nikiforov, Y.E.6
-
7
-
-
0028914404
-
Rearrangements of TRK proto-oncogene in papillary thyroid carcinomas
-
Pierotti, M. A., Bongarzone, I., Borrello, M. G., Mariani, C., Miranda, C., Sozzi, G., and Greco, A. Rearrangements of TRK proto-oncogene in papillary thyroid carcinomas. J. Endocrinol. Investig., 18: 130-133, 1995.
-
(1995)
J. Endocrinol. Investig.
, vol.18
, pp. 130-133
-
-
Pierotti, M.A.1
Bongarzone, I.2
Borrello, M.G.3
Mariani, C.4
Miranda, C.5
Sozzi, G.6
Greco, A.7
-
8
-
-
0025185363
-
Point mutations of ras oncogenes are an early event in thyroid tumorigenesis
-
Namba, H., Rubin, S. A., and Fagin, J. A. Point mutations of ras oncogenes are an early event in thyroid tumorigenesis. Mol. Endocrinol., 4: 1474-1479, 1990.
-
(1990)
Mol. Endocrinol.
, vol.4
, pp. 1474-1479
-
-
Namba, H.1
Rubin, S.A.2
Fagin, J.A.3
-
9
-
-
0029893933
-
A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins
-
Asai, N., Murakami, H., Iwashita, T., and Takahashi, M. A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins. J. Biol. Chem., 271: 17644-17649, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17644-17649
-
-
Asai, N.1
Murakami, H.2
Iwashita, T.3
Takahashi, M.4
-
10
-
-
0028104204
-
The ins and outs of Raf kinases
-
Daum, G., Eisenmann-Tappe, I., Fries, H. W., Troppmair, J., and Rapp, U. R. The ins and outs of Raf kinases. Trends Biochem. Sci., 19: 474-480, 1994.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 474-480
-
-
Daum, G.1
Eisenmann-Tappe, I.2
Fries, H.W.3
Troppmair, J.4
Rapp, U.R.5
-
11
-
-
0034762203
-
The Raf/MEK/ERK pathway: New concepts of activation
-
Peyssonnaux, C., and Eychene, A. The Raf/MEK/ERK pathway: new concepts of activation. Biol. Cell., 93: 53-62, 2001.
-
(2001)
Biol. Cell
, vol.93
, pp. 53-62
-
-
Peyssonnaux, C.1
Eychene, A.2
-
12
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies, H., Bignell, G. R., Cox, C., Stephens, P., Edkins, S., Clegg, S., Teague, J., Woffendin, H., Garnett, M. J., Bottomley, W., Davis, N., Dicks, E., Ewing, R., Floyd, Y., Gray, K., Hall, S., Hawes, R., Hughes, J., Kosmidou, V., Menzies, A., Mould, C., Parker, A., Stevens, C., Watt, S., Hooper, S., Wilson, R., Jayatilake, H., Gusterson, B. A., Cooper, C., Shipley, J., Hargrave, D., Pritchard-Jones, K., Maitland, N., Chenevix-Trench, G., Riggins, G. J., Bigner, D. D., Palmieri, G., Cossu, A., Flanagan, A., Nicholson, A., Ho, J. W., Leung, S. Y., Yuen, S. T., Weber, B. L., Seigler, H. F., Darrow, T. L., Paterson, H., Marais, R., Marshall, C. J., Wooster, R., Stratton, M. R., and Futreal, P. A. Mutations of the BRAF gene in human cancer. Nature (Lond.), 417: 949-954, 2002.
-
(2002)
Nature (Lond.)
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmieri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
13
-
-
0037194728
-
Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status
-
Rajagopalan, H., Bardelli, A., Lengauer, C., Kinzler, K. W., Vogelstein, B., and Velculescu, V. E. Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature (Lond.), 418: 934, 2002.
-
(2002)
Nature (Lond.)
, vol.418
, pp. 934
-
-
Rajagopalan, H.1
Bardelli, A.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
Velculescu, V.E.6
-
14
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
Fagin, J. A., Matsuo, K., Karmakar, A., Chen, D. L., Tang, S. H., and Koeffler, H. P. High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J. Clin. Investig., 91: 179-184, 1993.
-
(1993)
J. Clin. Investig.
, vol.91
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Chen, D.L.4
Tang, S.H.5
Koeffler, H.P.6
-
15
-
-
0029785721
-
Prevalence of mutations of ras and p53 in benign and malignant thyroid tumors from children exposed to radiation after the Chernobyl nuclear accident
-
Nikiforov, Y. E., Nikiforova, M. N., Gnepp, D. R., and Fagin, J. A. Prevalence of mutations of ras and p53 in benign and malignant thyroid tumors from children exposed to radiation after the Chernobyl nuclear accident. Oncogene, 13: 687-693, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 687-693
-
-
Nikiforov, Y.E.1
Nikiforova, M.N.2
Gnepp, D.R.3
Fagin, J.A.4
-
16
-
-
0027944338
-
Mutations of the adenomatous polyposis coli gene in sporadic thyroid neoplasms
-
Zeki, K., Spambalg, D., Sharifi, N., Gonsky, R., and Fagin, J. A. Mutations of the adenomatous polyposis coli gene in sporadic thyroid neoplasms. J. Clin. Endocrinol., 79: 1317-1321, 1994.
-
(1994)
J. Clin. Endocrinol.
, vol.79
, pp. 1317-1321
-
-
Zeki, K.1
Spambalg, D.2
Sharifi, N.3
Gonsky, R.4
Fagin, J.A.5
-
17
-
-
0032964297
-
BLAST 2 sequences, a new tool for comparing protein and nucleotide sequences
-
Tatusova, T. A., and Madden, T. L. BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences. FEMS Microbiol. Lett., 174: 247-250, 1999.
-
(1999)
FEMS Microbiol. Lett.
, vol.174
, pp. 247-250
-
-
Tatusova, T.A.1
Madden, T.L.2
-
18
-
-
0035122455
-
Multiplex PCR by multicolor fluorimetry and fluorescence melting curve analysis
-
Elenitoba-Johnson, K. S., Bohling, S. D., Wittwer, C. T., and King, T. C. Multiplex PCR by multicolor fluorimetry and fluorescence melting curve analysis. Nat. Med., 7: 249-253, 2001.
-
(2001)
Nat. Med.
, vol.7
, pp. 249-253
-
-
Elenitoba-Johnson, K.S.1
Bohling, S.D.2
Wittwer, C.T.3
King, T.C.4
-
19
-
-
0012683188
-
RAS point mutations and PAX8-PPARγ rearrangement in thyroid tumors: Evidence for distinct molecular pathways in thyroid follicular carcinoma
-
in press
-
Nikiforova, M. N., Lynch, R. A., Biddinger, P. W., Alexander, E. K., Dorn, G. W., Tallini, G., Kroll, T. G., and Nikiforov, Y. E. RAS point mutations and PAX8-PPARγ rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma. J. Clin. Endocrinol. Metab., in press, 2003.
-
(2003)
J. Clin. Endocrinol. Metab.
-
-
Nikiforova, M.N.1
Lynch, R.A.2
Biddinger, P.W.3
Alexander, E.K.4
Dorn, G.W.5
Tallini, G.6
Kroll, T.G.7
Nikiforov, Y.E.8
-
20
-
-
0026763062
-
Ret oucogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype
-
Santoro, M., Carlomagno, F., Hay, I. D., Herrmann, M. A., Grieco, M., Melillo, R., Pierotti, M. A., Bongarzone, I., Della Porta, G., Berger, N., and et al. Ret oucogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype. J. Clin. Investig., 89: 1517-1522, 1992.
-
(1992)
J. Clin. Investig.
, vol.89
, pp. 1517-1522
-
-
Santoro, M.1
Carlomagno, F.2
Hay, I.D.3
Herrmann, M.A.4
Grieco, M.5
Melillo, R.6
Pierotti, M.A.7
Bongarzone, I.8
Della Porta, G.9
Berger, N.10
-
21
-
-
0027548295
-
The TRK RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line
-
Santoro, M., Melillo, R. M., Grieco, M., Berlingieri, M. T., Vecchio, G., and Fusco, A. The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line. Cell Growth Differ., 4: 77-84, 1993.
-
(1993)
Cell Growth Differ.
, vol.4
, pp. 77-84
-
-
Santoro, M.1
Melillo, R.M.2
Grieco, M.3
Berlingieri, M.T.4
Vecchio, G.5
Fusco, A.6
-
22
-
-
0036295515
-
Molecular mechanisms of RET activation in human cancer
-
Santoro, M., Melillo, R. M., Carlomagno, F., Fusco, A., and Vecchio, G. Molecular mechanisms of RET activation in human cancer. Ann. N. Y. Acad. Sci., 963: 116-121, 2002.
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.963
, pp. 116-121
-
-
Santoro, M.1
Melillo, R.M.2
Carlomagno, F.3
Fusco, A.4
Vecchio, G.5
-
23
-
-
0035870623
-
RET rearrangements in radiation-induced papillary thyroid carcinomas: High prevalence of topoisomerase I sites at breakpoints and microhomology-mediated end joining in ELE1 and RET chimeric genes
-
Klugbauer, S., Pfeiffer, P., Gassenhuber, H., Beimfohr, C., and Rabes, H. M. RET rearrangements in radiation-induced papillary thyroid carcinomas: high prevalence of topoisomerase I sites at breakpoints and microhomology-mediated end joining in ELE1 and RET chimeric genes. Genomics, 73: 149-160, 2001.
-
(2001)
Genomics
, vol.73
, pp. 149-160
-
-
Klugbauer, S.1
Pfeiffer, P.2
Gassenhuber, H.3
Beimfohr, C.4
Rabes, H.M.5
-
24
-
-
0029781186
-
Molecular and biochemical analysis of RET/PTC4, a novel oncogenic rearrangement between RET and ELE1 genes, in a post-Chernobyl papillary thyroid cancer
-
Fugazzola, L., Pierotti, M. A., Vigano, E., Pacini, F., Vorontsova, T. V., and Bongarzone, I. Molecular and biochemical analysis of RET/PTC4, a novel oncogenic rearrangement between RET and ELE1 genes, in a post-Chernobyl papillary thyroid cancer. Oncogene. 13: 1093-1097, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 1093-1097
-
-
Fugazzola, L.1
Pierotti, M.A.2
Vigano, E.3
Pacini, F.4
Vorontsova, T.V.5
Bongarzone, I.6
-
25
-
-
0033524002
-
Chromosomal breakpoint positions suggest a direct role for radiation in inducing illegitimate recombination between the ELE1 and RET genes in radiation-induced thyroid carcinomas
-
Nikiforov, Y. E., Koshoffer, A., Nikiforova, M., Stringer, J., and Fagin, J. A. Chromosomal breakpoint positions suggest a direct role for radiation in inducing illegitimate recombination between the ELE1 and RET genes in radiation-induced thyroid carcinomas. Oncogene, 18: 6330-6334, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 6330-6334
-
-
Nikiforov, Y.E.1
Koshoffer, A.2
Nikiforova, M.3
Stringer, J.4
Fagin, J.A.5
-
26
-
-
0037117596
-
On the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b
-
Ribeiro-Neto, F., Urbani, J., Lemee, N., Lou, L., and Altschuler, D. L. On the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b. Proc. Natl. Acad. Sci. USA, 99: 5418-5423, 2002.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5418-5423
-
-
Ribeiro-Neto, F.1
Urbani, J.2
Lemee, N.3
Lou, L.4
Altschuler, D.L.5
-
27
-
-
0034659736
-
Ras mediates the cAMP-dependent activation of extracellular signal- regulated kinases (ERKs) in melanocytes
-
Busca, R., Abbe, P., Mantoux, F., Aberdam, E., Peyssonnaux, C., Eychene, A., Ortonne, J. P., and Ballotti, R. Ras mediates the cAMP-dependent activation of extracellular signal- regulated kinases (ERKs) in melanocytes. EMBO J., 19: 2900-2910, 2000.
-
(2000)
EMBO J.
, vol.19
, pp. 2900-2910
-
-
Busca, R.1
Abbe, P.2
Mantoux, F.3
Aberdam, E.4
Peyssonnaux, C.5
Eychene, A.6
Ortonne, J.P.7
Ballotti, R.8
-
28
-
-
0034721067
-
Cyclic AMP activates Ras
-
Tsygankova, O. M., Kupperman, E., Wen, W., and Meinkoth, J. L. Cyclic AMP activates Ras. Oncogene, 19: 3609-3615, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 3609-3615
-
-
Tsygankova, O.M.1
Kupperman, E.2
Wen, W.3
Meinkoth, J.L.4
-
29
-
-
0034753081
-
Thyrotropin activates mitogen-activated protein kinase pathway in FRTL- 5 by a cAMP-dependent protein kinase A-independent mechanism
-
Iacovelli, L., Capobianco, L., Salvatore, L., Sallese, M., D'Ancona, G. M., and De Blasi, A. Thyrotropin activates mitogen-activated protein kinase pathway in FRTL- 5 by a cAMP-dependent protein kinase A-independent mechanism. Mol. Pharmacol., 60: 924-933, 2001.
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 924-933
-
-
Iacovelli, L.1
Capobianco, L.2
Salvatore, L.3
Sallese, M.4
D'Ancona, G.M.5
De Blasi, A.6
-
30
-
-
0008212049
-
Prevalence of Ras mutations in thyroid neoplasia
-
Esapa, C. T., Johnson, S. J., Kendall-Taylor, P., Lennard, T. W., and Harris, P. E. Prevalence of Ras mutations in thyroid neoplasia. Clin. Endocrinol. (Oxf.), 50: 529-535, 1999.
-
(1999)
Clin. Endocrinol. (Oxf.)
, vol.50
, pp. 529-535
-
-
Esapa, C.T.1
Johnson, S.J.2
Kendall-Taylor, P.3
Lennard, T.W.4
Harris, P.E.5
|