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Volumn 83, Issue 2, 1998, Pages 554-559

Absence of activating mutations of the genes encoding the α-subunits of G11 and G(q) in thyroid neoplasia

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; AMINO ACID; DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOLIPASE C; THYROTROPIN RECEPTOR;

EID: 0031764971     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.2.554     Document Type: Article
Times cited : (9)

References (48)
  • 1
    • 0030030847 scopus 로고
    • The human thyrotropin receptor: A heptahelical receptor capable of stimulating members of all four G protein families
    • Laugwitz K-L, Allgeier A, Offermans S, et al. 1995 The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families. Proc Natl Acad Sci USA. 93:116-120.
    • (1995) Proc Natl Acad Sci USA , vol.93 , pp. 116-120
    • Laugwitz, K.-L.1    Allgeier, A.2    Offermans, S.3
  • 3
    • 0026743033 scopus 로고
    • The thyrotropin receptor and the regulation of thyrocyte function and growth
    • Vassart G, Dumont JE. 1992 The thyrotropin receptor and the regulation of thyrocyte function and growth. Endocr Rev. 13:596-611.
    • (1992) Endocr Rev , vol.13 , pp. 596-611
    • Vassart, G.1    Dumont, J.E.2
  • 5
    • 0023522307 scopus 로고
    • s and adenylate cyclase activity in human GH-secreting pituitary adenomas
    • s and adenylate cyclase activity in human GH-secreting pituitary adenomas. Nature. 330:566-568.
    • (1987) Nature , vol.330 , pp. 566-568
    • Vallar, L.1    Spada, A.2    Giannattasio, G.3
  • 6
    • 0027369421 scopus 로고
    • Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
    • Parma J, Duprez L, Van Sande J, et al. 1993 Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature. 365:649-651.
    • (1993) Nature , vol.365 , pp. 649-651
    • Parma, J.1    Duprez, L.2    Van Sande, J.3
  • 7
    • 0029964174 scopus 로고    scopus 로고
    • Thyrotropin receptor gene alterations in thyroid hyperfunctioning adenomas
    • Russo D, Arturi F, Suarez HG, et al. 1996 Thyrotropin receptor gene alterations in thyroid hyperfunctioning adenomas. J Clin Endocrinol Metab. 81:1548-1551.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1548-1551
    • Russo, D.1    Arturi, F.2    Suarez, H.G.3
  • 8
    • 0025127424 scopus 로고
    • Two C protein oncogenes in human endocrine tumors
    • Lyons J, Landis CA, Harsh G, et al. 1990 Two C protein oncogenes in human endocrine tumors. Science. 249:655-659.
    • (1990) Science , vol.249 , pp. 655-659
    • Lyons, J.1    Landis, C.A.2    Harsh, G.3
  • 12
    • 0026664955 scopus 로고
    • Mutational activation of ras and gsp oncogenes in differentiated thyroid cancer and their biological implications
    • Goretzki PE, Lyons J, Stacy-Phipps S, et al. 1992 Mutational activation of ras and gsp oncogenes in differentiated thyroid cancer and their biological implications. World J Surg. 16:576-582.
    • (1992) World J Surg , vol.16 , pp. 576-582
    • Goretzki, P.E.1    Lyons, J.2    Stacy-Phipps, S.3
  • 14
    • 0029799977 scopus 로고    scopus 로고
    • Structural studies of the thyrotropin receptor and Gs α in human thyroid cancers: Low prevalence of mutations predicts infrequent involvement in malignant transformation
    • Spambalg D, Sharifi N, Elisei R, Gross JL, Medeiros-Neto G, Fagin JA. 1996 Structural studies of the thyrotropin receptor and Gs α in human thyroid cancers: low prevalence of mutations predicts infrequent involvement in malignant transformation. J din Endocrinol Metab. 81:3898-3901.
    • (1996) J Din Endocrinol Metab , vol.81 , pp. 3898-3901
    • Spambalg, D.1    Sharifi, N.2    Elisei, R.3    Gross, J.L.4    Medeiros-Neto, G.5    Fagin, J.A.6
  • 15
    • 0028808086 scopus 로고
    • Activating mutations of the TSH receptor in differentiated thyroid carcinomas
    • Russo D, Arturi F, Schlumberger M, et al. 1995 Activating mutations of the TSH receptor in differentiated thyroid carcinomas. Oncogene. 11:1907-1911.
    • (1995) Oncogene , vol.11 , pp. 1907-1911
    • Russo, D.1    Arturi, F.2    Schlumberger, M.3
  • 16
    • 0029004783 scopus 로고
    • Point mutations in the thyrotropin receptor in human thyroid tumors
    • Ohno M, Endo T, Ohta K, Gunji K, Onaya T. 1995 Point mutations in the thyrotropin receptor in human thyroid tumors. Thyroid. 5:97-100.
    • (1995) Thyroid , vol.5 , pp. 97-100
    • Ohno, M.1    Endo, T.2    Ohta, K.3    Gunji, K.4    Onaya, T.5
  • 17
    • 0031059155 scopus 로고    scopus 로고
    • Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma
    • Russo D, Tumino S, Arturi F, et al. 1997 Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma. J Clin Endocrinol Metab. 82:735-738.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 735-738
    • Russo, D.1    Tumino, S.2    Arturi, F.3
  • 18
    • 0028240982 scopus 로고
    • Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism
    • Duprez L, Parma J, Van Sande J, et al. 1993 Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism. Nat Genet. 7:396-401.
    • (1993) Nat Genet , vol.7 , pp. 396-401
    • Duprez, L.1    Parma, J.2    Van Sande, J.3
  • 19
    • 0028891649 scopus 로고
    • Congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene
    • Kopp P, Van Sande J, Parma J, et al. 1995 Congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene. N Engl J Med. 332:150-154.
    • (1995) N Engl J Med , vol.332 , pp. 150-154
    • Kopp, P.1    Van Sande, J.2    Parma, J.3
  • 20
    • 0027988614 scopus 로고
    • Oncogenic potential of guanine nucleotide stimulatory factor α-subunit in thyroid glands of transgenic mice
    • Michiels F, Caillou B, Talbot M, et al. 1994 Oncogenic potential of guanine nucleotide stimulatory factor α-subunit in thyroid glands of transgenic mice. Proc Natl Acad Sci USA. 91:10488-10492.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10488-10492
    • Michiels, F.1    Caillou, B.2    Talbot, M.3
  • 21
    • 0026499881 scopus 로고
    • Thyroid expression of an A2 adenosine receptor induces thyroid hyperplasia and hyperthyroidism
    • Ledent C, Dumont JE, Vassart G, Parmentier M. 1992 Thyroid expression of an A2 adenosine receptor induces thyroid hyperplasia and hyperthyroidism. EMBO J. 11:537-542.
    • (1992) EMBO J , vol.11 , pp. 537-542
    • Ledent, C.1    Dumont, J.E.2    Vassart, G.3    Parmentier, M.4
  • 22
    • 0030741024 scopus 로고    scopus 로고
    • Thyroid-specific expression of cholera toxin A1 subunit causes thyroid hyperplasia and hyperthyroidism in transgenic mice
    • Zeiger MA, Saji M, Gesev Y, et al. 1997 Thyroid-specific expression of cholera toxin A1 subunit causes thyroid hyperplasia and hyperthyroidism in transgenic mice. Endocrinology. 138:3133-3140.
    • (1997) Endocrinology , vol.138 , pp. 3133-3140
    • Zeiger, M.A.1    Saji, M.2    Gesev, Y.3
  • 23
    • 0029053861 scopus 로고
    • Expression of functional stimulatory guanine nucleotide binding protein in nonfunctioning thyroid adenomas is not correlated to adenylate cyclase activity and growth of these tumors
    • Hamacher C, Studer H, Zbaeren J, Schatz H, Derwahl M. 1995 Expression of functional stimulatory guanine nucleotide binding protein in nonfunctioning thyroid adenomas is not correlated to adenylate cyclase activity and growth of these tumors. J Clin Endocrinol Metab. 80:1724-1732.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1724-1732
    • Hamacher, C.1    Studer, H.2    Zbaeren, J.3    Schatz, H.4    Derwahl, M.5
  • 24
    • 0025860413 scopus 로고
    • Activation of the beta 1 isozyme of phospholipase C by alpha-subunits of the Gq class of G protein
    • Taylor SJ, Chae HZ, Rhee SG, Exton JH. 1991 Activation of the beta 1 isozyme of phospholipase C by alpha-subunits of the Gq class of G protein. Nature. 350:516-518.
    • (1991) Nature , vol.350 , pp. 516-518
    • Taylor, S.J.1    Chae, H.Z.2    Rhee, S.G.3    Exton, J.H.4
  • 25
    • 0021832410 scopus 로고
    • Thorbol esters stimulate growth and inhibit differentiation in cultured thyroid cells
    • Bacharach LK, Eggo MC, Mak WW, Burrow GN. 1985 Thorbol esters stimulate growth and inhibit differentiation in cultured thyroid cells. Endocrinology. 116:1603-1609.
    • (1985) Endocrinology , vol.116 , pp. 1603-1609
    • Bacharach, L.K.1    Eggo, M.C.2    Mak, W.W.3    Burrow, G.N.4
  • 27
    • 0027422083 scopus 로고
    • Thyrotropin stimulates invasion and growth of follicular thyroid cancer cells via PKC-rather than PKC-activation
    • Hoelting T, Tezelman S, Siperstein AE, Duh Q-Y, Clark O. 1993 Thyrotropin stimulates invasion and growth of follicular thyroid cancer cells via PKC-rather than PKC-activation. Biochem Biophys Res Commun. 195:1230-1236.
    • (1993) Biochem Biophys Res Commun , vol.195 , pp. 1230-1236
    • Hoelting, T.1    Tezelman, S.2    Siperstein, A.E.3    Duh, Q.-Y.4    Clark, O.5
  • 29
    • 0031035909 scopus 로고    scopus 로고
    • 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells
    • 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells. Endocrinology. 138:369:378.
    • (1997) Endocrinology , vol.138 , pp. 369
    • Ledent, C.1    Denef, J.-F.2    Cottecchia, S.3
  • 30
    • 0024375478 scopus 로고
    • Characterization of a human follicular thyroid carcinoma cell line (UCLa RO82 W-1)
    • Eastor B, Van Herle AJ, Juillard GJF, et al. 1989 Characterization of a human follicular thyroid carcinoma cell line (UCLA RO82 W-1). Virchows Arch B Cell Pathol. 57:167-174.
    • (1989) Virchows Arch B Cell Pathol , vol.57 , pp. 167-174
    • Eastor, B.1    Van Herle, A.J.2    Juillard, G.J.F.3
  • 31
    • 0029561167 scopus 로고
    • Molecular cloning of human Gαq cDNa and chromosomal localization or the Gαq gene (GNAQ) and a processed pseudogene
    • Dong Q, Shenker A, Way J, et al. 1995 Molecular cloning of human Gαq cDNA and chromosomal localization or the Gαq gene (GNAQ) and a processed pseudogene. Genomics. 30:470-475.
    • (1995) Genomics , vol.30 , pp. 470-475
    • Dong, Q.1    Shenker, A.2    Way, J.3
  • 32
    • 0025822397 scopus 로고
    • Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells
    • Jiang M, Pandey S, Tran VT, Fong HK. 1991 Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells. Proc Natl Acad Sci USA. 88:3907-3911.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3907-3911
    • Jiang, M.1    Pandey, S.2    Tran, V.T.3    Fong, H.K.4
  • 33
    • 0025167972 scopus 로고
    • Comprehensive detection of single base changes in human genomic DNa using denaturing gradient gel electrophoresis and a GC clamp
    • Abrams ES, Murdaugh SE, Lerman LS. 1990 Comprehensive detection of single base changes in human genomic DNA using denaturing gradient gel electrophoresis and a GC clamp. Genomics. 7:463-475.
    • (1990) Genomics , vol.7 , pp. 463-475
    • Abrams, E.S.1    Murdaugh, S.E.2    Lerman, L.S.3
  • 34
    • 0027210606 scopus 로고
    • Heterogeneous mutations in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in Albright hereditary osteodystrophy
    • Miric A, Vechia JD, Levine MA. 1493 Heterogeneous mutations in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in Albright hereditary osteodystrophy. J Clin Endocrinol Metab. 17:1560-1568.
    • (1493) J Clin Endocrinol Metab , vol.17 , pp. 1560-1568
    • Miric, A.1    Vechia, J.D.2    Levine, M.A.3
  • 35
    • 0001279038 scopus 로고
    • Preparation of genomic DNA from bacteria
    • Ausubel FM, Brent R, Kingston RE, et al., eds. Wiley
    • Wilson K. 1995 Preparation of genomic DNA from bacteria. In: Current protocols in molecular biology. Ausubel FM, Brent R, Kingston RE, et al., eds. Wiley; 2.41-2.45.
    • (1995) Current Protocols in Molecular Biology , pp. 241-245
    • Wilson, K.1
  • 36
    • 15444355236 scopus 로고
    • Enhanced phospholipase C stimulation and transformation in NIH3T3 cells expressing Q209L Gq-α-subunits
    • Devivo M, Chen J, Codina J, Iyengar R. 1992 Enhanced phospholipase C stimulation and transformation in NIH3T3 cells expressing Q209L Gq-α-subunits. J Biol Chem. 269:17417-17423.
    • (1992) J Biol Chem , vol.269 , pp. 17417-17423
    • Devivo, M.1    Chen, J.2    Codina, J.3    Iyengar, R.4
  • 37
    • 0026725897 scopus 로고
    • Mutated α-subunit of the Gq protein induces malignant transformation in NIH3T3 cells
    • Kalinec G, Nagaradi AJ, Hermouet S, Xu N, Gutkind JS. 1992 Mutated α-subunit of the Gq protein induces malignant transformation in NIH3T3 cells. Mol Cell Biol. 12:46887-46893.
    • (1992) Mol Cell Biol , vol.12 , pp. 46887-46893
    • Kalinec, G.1    Nagaradi, A.J.2    Hermouet, S.3    Xu, N.4    Gutkind, J.S.5
  • 39
    • 0029981230 scopus 로고    scopus 로고
    • Screening of candidate oncogenes in human thyrotroph tumors: Absence of activating mutations of the Gαq, Gα11, Gαs, or thyrotropin-releasing hormone receptor genes
    • Dong Q, Brucker-Davis F, Weintraub BD, et al. 1996 Screening of candidate oncogenes in human thyrotroph tumors: absence of activating mutations of the Gαq, Gα11, Gαs, or thyrotropin-releasing hormone receptor genes. J Clin Endocrinol Metab. 81:1134-1140.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1134-1140
    • Dong, Q.1    Brucker-Davis, F.2    Weintraub, B.D.3
  • 40
    • 0026694168 scopus 로고
    • Identification of a mutation in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome
    • Schwindinger WF, Francomano CA, Levine MA. 1992 Identification of a mutation in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome. Proc Natl Acad Sci USA. 898:5152-5156.
    • (1992) Proc Natl Acad Sci USA , vol.898 , pp. 5152-5156
    • Schwindinger, W.F.1    Francomano, C.A.2    Levine, M.A.3
  • 41
    • 0026552008 scopus 로고
    • Analysis of the preproPTH gene by denaturing gradient gel electrophoresis in familial isolated hypoparathyroidism
    • Miric A, Levine MA. 1992 Analysis of the preproPTH gene by denaturing gradient gel electrophoresis in familial isolated hypoparathyroidism. J Clin Endocrinol Metab. 74:509-516.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 509-516
    • Miric, A.1    Levine, M.A.2
  • 42
    • 0029011084 scopus 로고
    • G protein-coupled receptor systems involved in cell growth and oncogenesis
    • Dhanasekaren N, Heasley LE, Johnson GL. 1995 G protein-coupled receptor systems involved in cell growth and oncogenesis. Endocr Rev. 16:259-270.
    • (1995) Endocr Rev , vol.16 , pp. 259-270
    • Dhanasekaren, N.1    Heasley, L.E.2    Johnson, G.L.3
  • 45
    • 0029081447 scopus 로고
    • Mechanisms of nonneoplastic endocrine hyperplasia- A changing concept: A review focused on the thyroid gland
    • Studer H, Derwahl M. 1995 Mechanisms of nonneoplastic endocrine hyperplasia-a changing concept: a review focused on the thyroid gland. Endocr Rev. 16:411-426.
    • (1995) Endocr Rev , vol.16 , pp. 411-426
    • Studer, H.1    Derwahl, M.2
  • 47
    • 0028972039 scopus 로고
    • 2+ influx and protein kinase C activation in sustained cellular responses
    • 2+ influx and protein kinase C activation in sustained cellular responses. Endocr Rev. 16:649-681.
    • (1995) Endocr Rev , vol.16 , pp. 649-681
    • Rasmussen, H.1    Isales, C.M.2    Calle, R.3
  • 48
    • 0031037296 scopus 로고    scopus 로고
    • Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ
    • Lopez-Ilasaca M, Crespo P, Pellici PG, Gutkind JS, Wetzker R. 1997 Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ. Science. 275:394-397.
    • (1997) Science , vol.275 , pp. 394-397
    • Lopez-Ilasaca, M.1    Crespo, P.2    Pellici, P.G.3    Gutkind, J.S.4    Wetzker, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.