-
1
-
-
0030030847
-
The human thyrotropin receptor: A heptahelical receptor capable of stimulating members of all four G protein families
-
Laugwitz K-L, Allgeier A, Offermans S, et al. 1995 The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families. Proc Natl Acad Sci USA. 93:116-120.
-
(1995)
Proc Natl Acad Sci USA
, vol.93
, pp. 116-120
-
-
Laugwitz, K.-L.1
Allgeier, A.2
Offermans, S.3
-
3
-
-
0026743033
-
The thyrotropin receptor and the regulation of thyrocyte function and growth
-
Vassart G, Dumont JE. 1992 The thyrotropin receptor and the regulation of thyrocyte function and growth. Endocr Rev. 13:596-611.
-
(1992)
Endocr Rev
, vol.13
, pp. 596-611
-
-
Vassart, G.1
Dumont, J.E.2
-
5
-
-
0023522307
-
s and adenylate cyclase activity in human GH-secreting pituitary adenomas
-
s and adenylate cyclase activity in human GH-secreting pituitary adenomas. Nature. 330:566-568.
-
(1987)
Nature
, vol.330
, pp. 566-568
-
-
Vallar, L.1
Spada, A.2
Giannattasio, G.3
-
6
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
Parma J, Duprez L, Van Sande J, et al. 1993 Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature. 365:649-651.
-
(1993)
Nature
, vol.365
, pp. 649-651
-
-
Parma, J.1
Duprez, L.2
Van Sande, J.3
-
7
-
-
0029964174
-
Thyrotropin receptor gene alterations in thyroid hyperfunctioning adenomas
-
Russo D, Arturi F, Suarez HG, et al. 1996 Thyrotropin receptor gene alterations in thyroid hyperfunctioning adenomas. J Clin Endocrinol Metab. 81:1548-1551.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1548-1551
-
-
Russo, D.1
Arturi, F.2
Suarez, H.G.3
-
8
-
-
0025127424
-
Two C protein oncogenes in human endocrine tumors
-
Lyons J, Landis CA, Harsh G, et al. 1990 Two C protein oncogenes in human endocrine tumors. Science. 249:655-659.
-
(1990)
Science
, vol.249
, pp. 655-659
-
-
Lyons, J.1
Landis, C.A.2
Harsh, G.3
-
9
-
-
0026009016
-
Activating point mutations in the gsp oncogene in human thyroid adenomas
-
O'Sullivan C, Barton CM, Staddon SL, Brown CL, Lemoine NR. 1991 Activating point mutations in the gsp oncogene in human thyroid adenomas. Mol Carcinog. 4:345-349.
-
(1991)
Mol Carcinog
, vol.4
, pp. 345-349
-
-
O'Sullivan, C.1
Barton, C.M.2
Staddon, S.L.3
Brown, C.L.4
Lemoine, N.R.5
-
10
-
-
0025865247
-
gsp mutations in human thyroid tumors
-
Suarez HG, du Villard JA, Caillou B, Schlumberger M, Parmentier C, Monier R. 1991 gsp mutations in human thyroid tumors. Oncogene. 6:677-679.
-
(1991)
Oncogene
, vol.6
, pp. 677-679
-
-
Suarez, H.G.1
Du Villard, J.A.2
Caillou, B.3
Schlumberger, M.4
Parmentier, C.5
Monier, R.6
-
12
-
-
0026664955
-
Mutational activation of ras and gsp oncogenes in differentiated thyroid cancer and their biological implications
-
Goretzki PE, Lyons J, Stacy-Phipps S, et al. 1992 Mutational activation of ras and gsp oncogenes in differentiated thyroid cancer and their biological implications. World J Surg. 16:576-582.
-
(1992)
World J Surg
, vol.16
, pp. 576-582
-
-
Goretzki, P.E.1
Lyons, J.2
Stacy-Phipps, S.3
-
13
-
-
0031035250
-
G protein and thyrotropin receptor mutations in thyroid neoplasia
-
Esapa C, Foster S, Johnson S, Jameson JL, Kendall-Taylor P, Harris PE. 1997 G protein and thyrotropin receptor mutations in thyroid neoplasia. J Clin Endocrinol Metab. 82:493-496.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 493-496
-
-
Esapa, C.1
Foster, S.2
Johnson, S.3
Jameson, J.L.4
Kendall-Taylor, P.5
Harris, P.E.6
-
14
-
-
0029799977
-
Structural studies of the thyrotropin receptor and Gs α in human thyroid cancers: Low prevalence of mutations predicts infrequent involvement in malignant transformation
-
Spambalg D, Sharifi N, Elisei R, Gross JL, Medeiros-Neto G, Fagin JA. 1996 Structural studies of the thyrotropin receptor and Gs α in human thyroid cancers: low prevalence of mutations predicts infrequent involvement in malignant transformation. J din Endocrinol Metab. 81:3898-3901.
-
(1996)
J Din Endocrinol Metab
, vol.81
, pp. 3898-3901
-
-
Spambalg, D.1
Sharifi, N.2
Elisei, R.3
Gross, J.L.4
Medeiros-Neto, G.5
Fagin, J.A.6
-
15
-
-
0028808086
-
Activating mutations of the TSH receptor in differentiated thyroid carcinomas
-
Russo D, Arturi F, Schlumberger M, et al. 1995 Activating mutations of the TSH receptor in differentiated thyroid carcinomas. Oncogene. 11:1907-1911.
-
(1995)
Oncogene
, vol.11
, pp. 1907-1911
-
-
Russo, D.1
Arturi, F.2
Schlumberger, M.3
-
16
-
-
0029004783
-
Point mutations in the thyrotropin receptor in human thyroid tumors
-
Ohno M, Endo T, Ohta K, Gunji K, Onaya T. 1995 Point mutations in the thyrotropin receptor in human thyroid tumors. Thyroid. 5:97-100.
-
(1995)
Thyroid
, vol.5
, pp. 97-100
-
-
Ohno, M.1
Endo, T.2
Ohta, K.3
Gunji, K.4
Onaya, T.5
-
17
-
-
0031059155
-
Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma
-
Russo D, Tumino S, Arturi F, et al. 1997 Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma. J Clin Endocrinol Metab. 82:735-738.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 735-738
-
-
Russo, D.1
Tumino, S.2
Arturi, F.3
-
18
-
-
0028240982
-
Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism
-
Duprez L, Parma J, Van Sande J, et al. 1993 Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism. Nat Genet. 7:396-401.
-
(1993)
Nat Genet
, vol.7
, pp. 396-401
-
-
Duprez, L.1
Parma, J.2
Van Sande, J.3
-
19
-
-
0028891649
-
Congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene
-
Kopp P, Van Sande J, Parma J, et al. 1995 Congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene. N Engl J Med. 332:150-154.
-
(1995)
N Engl J Med
, vol.332
, pp. 150-154
-
-
Kopp, P.1
Van Sande, J.2
Parma, J.3
-
20
-
-
0027988614
-
Oncogenic potential of guanine nucleotide stimulatory factor α-subunit in thyroid glands of transgenic mice
-
Michiels F, Caillou B, Talbot M, et al. 1994 Oncogenic potential of guanine nucleotide stimulatory factor α-subunit in thyroid glands of transgenic mice. Proc Natl Acad Sci USA. 91:10488-10492.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10488-10492
-
-
Michiels, F.1
Caillou, B.2
Talbot, M.3
-
21
-
-
0026499881
-
Thyroid expression of an A2 adenosine receptor induces thyroid hyperplasia and hyperthyroidism
-
Ledent C, Dumont JE, Vassart G, Parmentier M. 1992 Thyroid expression of an A2 adenosine receptor induces thyroid hyperplasia and hyperthyroidism. EMBO J. 11:537-542.
-
(1992)
EMBO J
, vol.11
, pp. 537-542
-
-
Ledent, C.1
Dumont, J.E.2
Vassart, G.3
Parmentier, M.4
-
22
-
-
0030741024
-
Thyroid-specific expression of cholera toxin A1 subunit causes thyroid hyperplasia and hyperthyroidism in transgenic mice
-
Zeiger MA, Saji M, Gesev Y, et al. 1997 Thyroid-specific expression of cholera toxin A1 subunit causes thyroid hyperplasia and hyperthyroidism in transgenic mice. Endocrinology. 138:3133-3140.
-
(1997)
Endocrinology
, vol.138
, pp. 3133-3140
-
-
Zeiger, M.A.1
Saji, M.2
Gesev, Y.3
-
23
-
-
0029053861
-
Expression of functional stimulatory guanine nucleotide binding protein in nonfunctioning thyroid adenomas is not correlated to adenylate cyclase activity and growth of these tumors
-
Hamacher C, Studer H, Zbaeren J, Schatz H, Derwahl M. 1995 Expression of functional stimulatory guanine nucleotide binding protein in nonfunctioning thyroid adenomas is not correlated to adenylate cyclase activity and growth of these tumors. J Clin Endocrinol Metab. 80:1724-1732.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 1724-1732
-
-
Hamacher, C.1
Studer, H.2
Zbaeren, J.3
Schatz, H.4
Derwahl, M.5
-
24
-
-
0025860413
-
Activation of the beta 1 isozyme of phospholipase C by alpha-subunits of the Gq class of G protein
-
Taylor SJ, Chae HZ, Rhee SG, Exton JH. 1991 Activation of the beta 1 isozyme of phospholipase C by alpha-subunits of the Gq class of G protein. Nature. 350:516-518.
-
(1991)
Nature
, vol.350
, pp. 516-518
-
-
Taylor, S.J.1
Chae, H.Z.2
Rhee, S.G.3
Exton, J.H.4
-
25
-
-
0021832410
-
Thorbol esters stimulate growth and inhibit differentiation in cultured thyroid cells
-
Bacharach LK, Eggo MC, Mak WW, Burrow GN. 1985 Thorbol esters stimulate growth and inhibit differentiation in cultured thyroid cells. Endocrinology. 116:1603-1609.
-
(1985)
Endocrinology
, vol.116
, pp. 1603-1609
-
-
Bacharach, L.K.1
Eggo, M.C.2
Mak, W.W.3
Burrow, G.N.4
-
26
-
-
0027252699
-
Increased phospholipase C activity in neoplastic thyroid membrane
-
Kobayashi K, Shaver J, Liang W, Siperstein A, Duh Q-Y, Clark O. 1993 Increased phospholipase C activity in neoplastic thyroid membrane. Thyroid. 3:25-29.
-
(1993)
Thyroid
, vol.3
, pp. 25-29
-
-
Kobayashi, K.1
Shaver, J.2
Liang, W.3
Siperstein, A.4
Duh, Q.-Y.5
Clark, O.6
-
27
-
-
0027422083
-
Thyrotropin stimulates invasion and growth of follicular thyroid cancer cells via PKC-rather than PKC-activation
-
Hoelting T, Tezelman S, Siperstein AE, Duh Q-Y, Clark O. 1993 Thyrotropin stimulates invasion and growth of follicular thyroid cancer cells via PKC-rather than PKC-activation. Biochem Biophys Res Commun. 195:1230-1236.
-
(1993)
Biochem Biophys Res Commun
, vol.195
, pp. 1230-1236
-
-
Hoelting, T.1
Tezelman, S.2
Siperstein, A.E.3
Duh, Q.-Y.4
Clark, O.5
-
29
-
-
0031035909
-
1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells
-
1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells. Endocrinology. 138:369:378.
-
(1997)
Endocrinology
, vol.138
, pp. 369
-
-
Ledent, C.1
Denef, J.-F.2
Cottecchia, S.3
-
30
-
-
0024375478
-
Characterization of a human follicular thyroid carcinoma cell line (UCLa RO82 W-1)
-
Eastor B, Van Herle AJ, Juillard GJF, et al. 1989 Characterization of a human follicular thyroid carcinoma cell line (UCLA RO82 W-1). Virchows Arch B Cell Pathol. 57:167-174.
-
(1989)
Virchows Arch B Cell Pathol
, vol.57
, pp. 167-174
-
-
Eastor, B.1
Van Herle, A.J.2
Juillard, G.J.F.3
-
31
-
-
0029561167
-
Molecular cloning of human Gαq cDNa and chromosomal localization or the Gαq gene (GNAQ) and a processed pseudogene
-
Dong Q, Shenker A, Way J, et al. 1995 Molecular cloning of human Gαq cDNA and chromosomal localization or the Gαq gene (GNAQ) and a processed pseudogene. Genomics. 30:470-475.
-
(1995)
Genomics
, vol.30
, pp. 470-475
-
-
Dong, Q.1
Shenker, A.2
Way, J.3
-
32
-
-
0025822397
-
Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells
-
Jiang M, Pandey S, Tran VT, Fong HK. 1991 Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells. Proc Natl Acad Sci USA. 88:3907-3911.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3907-3911
-
-
Jiang, M.1
Pandey, S.2
Tran, V.T.3
Fong, H.K.4
-
33
-
-
0025167972
-
Comprehensive detection of single base changes in human genomic DNa using denaturing gradient gel electrophoresis and a GC clamp
-
Abrams ES, Murdaugh SE, Lerman LS. 1990 Comprehensive detection of single base changes in human genomic DNA using denaturing gradient gel electrophoresis and a GC clamp. Genomics. 7:463-475.
-
(1990)
Genomics
, vol.7
, pp. 463-475
-
-
Abrams, E.S.1
Murdaugh, S.E.2
Lerman, L.S.3
-
34
-
-
0027210606
-
Heterogeneous mutations in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in Albright hereditary osteodystrophy
-
Miric A, Vechia JD, Levine MA. 1493 Heterogeneous mutations in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in Albright hereditary osteodystrophy. J Clin Endocrinol Metab. 17:1560-1568.
-
(1493)
J Clin Endocrinol Metab
, vol.17
, pp. 1560-1568
-
-
Miric, A.1
Vechia, J.D.2
Levine, M.A.3
-
35
-
-
0001279038
-
Preparation of genomic DNA from bacteria
-
Ausubel FM, Brent R, Kingston RE, et al., eds. Wiley
-
Wilson K. 1995 Preparation of genomic DNA from bacteria. In: Current protocols in molecular biology. Ausubel FM, Brent R, Kingston RE, et al., eds. Wiley; 2.41-2.45.
-
(1995)
Current Protocols in Molecular Biology
, pp. 241-245
-
-
Wilson, K.1
-
36
-
-
15444355236
-
Enhanced phospholipase C stimulation and transformation in NIH3T3 cells expressing Q209L Gq-α-subunits
-
Devivo M, Chen J, Codina J, Iyengar R. 1992 Enhanced phospholipase C stimulation and transformation in NIH3T3 cells expressing Q209L Gq-α-subunits. J Biol Chem. 269:17417-17423.
-
(1992)
J Biol Chem
, vol.269
, pp. 17417-17423
-
-
Devivo, M.1
Chen, J.2
Codina, J.3
Iyengar, R.4
-
37
-
-
0026725897
-
Mutated α-subunit of the Gq protein induces malignant transformation in NIH3T3 cells
-
Kalinec G, Nagaradi AJ, Hermouet S, Xu N, Gutkind JS. 1992 Mutated α-subunit of the Gq protein induces malignant transformation in NIH3T3 cells. Mol Cell Biol. 12:46887-46893.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 46887-46893
-
-
Kalinec, G.1
Nagaradi, A.J.2
Hermouet, S.3
Xu, N.4
Gutkind, J.S.5
-
39
-
-
0029981230
-
Screening of candidate oncogenes in human thyrotroph tumors: Absence of activating mutations of the Gαq, Gα11, Gαs, or thyrotropin-releasing hormone receptor genes
-
Dong Q, Brucker-Davis F, Weintraub BD, et al. 1996 Screening of candidate oncogenes in human thyrotroph tumors: absence of activating mutations of the Gαq, Gα11, Gαs, or thyrotropin-releasing hormone receptor genes. J Clin Endocrinol Metab. 81:1134-1140.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1134-1140
-
-
Dong, Q.1
Brucker-Davis, F.2
Weintraub, B.D.3
-
40
-
-
0026694168
-
Identification of a mutation in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome
-
Schwindinger WF, Francomano CA, Levine MA. 1992 Identification of a mutation in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome. Proc Natl Acad Sci USA. 898:5152-5156.
-
(1992)
Proc Natl Acad Sci USA
, vol.898
, pp. 5152-5156
-
-
Schwindinger, W.F.1
Francomano, C.A.2
Levine, M.A.3
-
41
-
-
0026552008
-
Analysis of the preproPTH gene by denaturing gradient gel electrophoresis in familial isolated hypoparathyroidism
-
Miric A, Levine MA. 1992 Analysis of the preproPTH gene by denaturing gradient gel electrophoresis in familial isolated hypoparathyroidism. J Clin Endocrinol Metab. 74:509-516.
-
(1992)
J Clin Endocrinol Metab
, vol.74
, pp. 509-516
-
-
Miric, A.1
Levine, M.A.2
-
42
-
-
0029011084
-
G protein-coupled receptor systems involved in cell growth and oncogenesis
-
Dhanasekaren N, Heasley LE, Johnson GL. 1995 G protein-coupled receptor systems involved in cell growth and oncogenesis. Endocr Rev. 16:259-270.
-
(1995)
Endocr Rev
, vol.16
, pp. 259-270
-
-
Dhanasekaren, N.1
Heasley, L.E.2
Johnson, G.L.3
-
43
-
-
0028909901
-
G-protein mutations in human pituitary adrenocorticotrophic hormone-secreting adenomas
-
Williamson EA, Ince PG, Harrison D, Kendall-Taylor P, Harris PE. 1995 G-protein mutations in human pituitary adrenocorticotrophic hormone-secreting adenomas. Eur J Clin Invest. 25:128-131.
-
(1995)
Eur J Clin Invest
, vol.25
, pp. 128-131
-
-
Williamson, E.A.1
Ince, P.G.2
Harrison, D.3
Kendall-Taylor, P.4
Harris, P.E.5
-
45
-
-
0029081447
-
Mechanisms of nonneoplastic endocrine hyperplasia- A changing concept: A review focused on the thyroid gland
-
Studer H, Derwahl M. 1995 Mechanisms of nonneoplastic endocrine hyperplasia-a changing concept: a review focused on the thyroid gland. Endocr Rev. 16:411-426.
-
(1995)
Endocr Rev
, vol.16
, pp. 411-426
-
-
Studer, H.1
Derwahl, M.2
-
46
-
-
84995816299
-
Polyclonal and clonal nodules may coexist within multinodular goiters
-
Kopp P, Aeschimann S, Asmis L, Tobler A, Fey MF, Studer H. 1994 Polyclonal and clonal nodules may coexist within multinodular goiters. J Clin Endocrinol Metab. 79:134-139.
-
(1994)
J Clin Endocrinol Metab
, vol.79
, pp. 134-139
-
-
Kopp, P.1
Aeschimann, S.2
Asmis, L.3
Tobler, A.4
Fey, M.F.5
Studer, H.6
-
47
-
-
0028972039
-
2+ influx and protein kinase C activation in sustained cellular responses
-
2+ influx and protein kinase C activation in sustained cellular responses. Endocr Rev. 16:649-681.
-
(1995)
Endocr Rev
, vol.16
, pp. 649-681
-
-
Rasmussen, H.1
Isales, C.M.2
Calle, R.3
-
48
-
-
0031037296
-
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ
-
Lopez-Ilasaca M, Crespo P, Pellici PG, Gutkind JS, Wetzker R. 1997 Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ. Science. 275:394-397.
-
(1997)
Science
, vol.275
, pp. 394-397
-
-
Lopez-Ilasaca, M.1
Crespo, P.2
Pellici, P.G.3
Gutkind, J.S.4
Wetzker, R.5
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