Mutation analysis of the Epac-Rap1 signaling pathway in cold thyroid follicular adenomas

European Journal of Endocrinology

Volumn 144, Issue 6, 2001, Pages 605-610

  Vanvooren, V ^a   Allgeier, A ^a   Nguyen, M ^a   Massart, C ^a   Parma, J ^a   Dumont, J E ^a   Van Sande, J ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; COMPLEMENTARY DNA; CYCLIC AMP; CYCLIC AMP BINDING PROTEIN; DNA; GLYCINE; GUANINE NUCLEOTIDE BINDING PROTEIN; RAP PROTEIN; SERINE; THYROTROPIN RECEPTOR;

ADULT; ALPHA CHAIN; ARTICLE; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; DNA FLANKING REGION; DNA STRAND; FEMALE; GENE ACTIVATION; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN POLYMORPHISM; PROTEIN TARGETING; SIGNAL TRANSDUCTION; THYROID ADENOMA; THYROID CELL; THYROID FOLLICLE; THYROID GLAND; THYROID NODULE; THYROID TUMOR;

EID: 0034980681     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1440605     Document Type: Article

References (26)

1. Constitutively active receptors as a disease-causing mechanism
2. Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter
3. - symporter gene in human thyroid tumors: A comparison study with other thyroid-specific genes
4. TSH receptor mutations and thyroid disease
5. The thyrotropin receptor (TSH-R) is not an oncogene for thyroid tumors: Structural studies of the TSH-R and the alpha-subunit of Gs in human thyroid neoplasms
6. Genetic analysis of the TSH receptor gene in differentiated human thyroid carcinomas
7. Genetic alterations in human epithelial thyroid tumours
8. Role of Ras mutations in the progression of thyroid carcinoma of follicular epithelial origin
9. Toward a molecular definition of long-term memory storage
10. cAMP-dependent protein kinase. Model for an enzyme
11. Multiple pathway signal transduction by the cAMP-dependent protein kinase
12. Activation of cyclic AMP-dependent kinase is required but may not be sufficient to mimic cyclic AMP-dependent DNA synthesis and thyroglobulin expression in dog thyroid cells
13. Cyclic nucleotide gated channels as regulators of CNS development and plasticity
14. A family of cAMP-binding proteins that directly activate Rap1
15. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
16. Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1
17. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
18. Maintenance of human T cell anergy: Blocking of IL-2 gene transcription by activated Rap1
19. 2+-mediated activation of Rap1 in human platelets
20. Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 cells induces DNA synthesis and morphological changes
21. Mitogenic and oncogenic properties of the small G protein Rap1b
22. Genetic analysis of the K-rev-1 transformation-suppressor gene
23. Alterations in the rap1 signaling pathway are common in human gliomas
24. Activation of the small G protein Rap1 in dog thyroid cells by both cAMP-dependent and -independent pathways
25. Glutathione S-transferase M1 polymorphism and lung cancer risk in African-Americans
26. Association of ACE I/D polymorphism with cardiovascular risk factors