-
1
-
-
24344462460
-
Thyroid and parathyroid tumors
-
DeLellis RA, Lloyd RV, Heitz PU, Eng C, editors. International Agency for Research on Cancer (Lyons, France): IARC Press
-
DeLellis RA, Williams ED. Thyroid and parathyroid tumors. In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, editors. Tumours of endocrine organs. World Health Organization classification of tumors. International Agency for Research on Cancer (Lyons, France): IARC Press: 2004. p. 51-6.
-
(2004)
Tumours of Endocrine Organs. World Health Organization Classification of Tumors
, pp. 51-56
-
-
DeLellis, R.A.1
Williams, E.D.2
-
2
-
-
0037425748
-
Thyroid carcinoma
-
Sherman SI. Thyroid carcinoma. Lancet 2003;361:501-11.
-
(2003)
Lancet
, vol.361
, pp. 501-511
-
-
Sherman, S.I.1
-
3
-
-
23844527993
-
Undiffer-entiated (anaplastic) carcinoma
-
DeLellis RA, Lloyd RV, Heitz PU, Eng C, editors. International Agency for Research on Cancer (Lyons, France): IARC Press
-
Ordonez N, Baloch Z, Matias-Guiu X, et al. Undiffer-entiated (anaplastic) carcinoma. In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, editors. Tumours of endocrine organs, World Health Organization classification of tumors. International Agency for Research on Cancer (Lyons, France): IARC Press: 2004. p. 77-80.
-
(2004)
Tumours of Endocrine Organs, World Health Organization Classification of Tumors
, pp. 77-80
-
-
Ordonez, N.1
Baloch, Z.2
Matias-Guiu, X.3
-
4
-
-
0031755746
-
Anaplastic thyroid carcinoma: A therapeutic challenge
-
Ain KB. Anaplastic thyroid carcinoma: a therapeutic challenge. Semin Surg Oncol 1999;16:64-9.
-
(1999)
Semin Surg Oncol
, vol.16
, pp. 64-69
-
-
Ain, K.B.1
-
5
-
-
0037249255
-
Anaplastic thyroid cancer
-
Pasieka JL. Anaplastic thyroid cancer. Curr Opin Oncol 2003;15:78-83.
-
(2003)
Curr Opin Oncol
, vol.15
, pp. 78-83
-
-
Pasieka, J.L.1
-
6
-
-
0042885906
-
BRAF as a potential therapeutic target in melanoma and other malignancies
-
Tuveson DA, Weber BL, Herlyn M. BRAF as a potential therapeutic target in melanoma and other malignancies. Cancer Cell 2003;4:95-8.
-
(2003)
Cancer Cell
, vol.4
, pp. 95-98
-
-
Tuveson, D.A.1
Weber, B.L.2
Herlyn, M.3
-
7
-
-
0037379904
-
High prevalence of BR AF mutations in thyroid cancer: Genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
-
Kimura ET, Nikiforova MN, Zhu Z, Knauf JA, Nikiforov YE, Fagin JA. High prevalence of BR AF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res 2003;63:1454-7.
-
(2003)
Cancer Res
, vol.63
, pp. 1454-1457
-
-
Kimura, E.T.1
Nikiforova, M.N.2
Zhu, Z.3
Knauf, J.A.4
Nikiforov, Y.E.5
Fagin, J.A.6
-
8
-
-
0038664387
-
BRAF mutation in papillary thyroid carcinoma
-
Cohen Y, Xing M, Mambo E, et al. BRAF mutation in papillary thyroid carcinoma. J Natl Cancer Inst 2003;95:625-7.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 625-627
-
-
Cohen, Y.1
Xing, M.2
Mambo, E.3
-
9
-
-
0043170833
-
BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesisof PTC
-
Soares P, Trovisco V, Rocha AS, et al. BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesisof PTC Oncogene 2003;22:4578-80.
-
(2003)
Oncogene
, vol.22
, pp. 4578-4580
-
-
Soares, P.1
Trovisco, V.2
Rocha, A.S.3
-
10
-
-
0041589377
-
High prevalence of BRAF gene mutation in papillary thyroid carcinomas and thyroid tumor cell lines
-
Xu X, Quiros RM, Gattuso P, Ain KB, Prinz RA. High prevalence of BRAF gene mutation in papillary thyroid carcinomas and thyroid tumor cell lines. Cancer Res 2003;63:4561-7.
-
(2003)
Cancer Res
, vol.63
, pp. 4561-4567
-
-
Xu, X.1
Quiros, R.M.2
Gattuso, P.3
Ain, K.B.4
Prinz, R.A.5
-
11
-
-
1642323622
-
BRAF T1796A transversion mutation in various thyroid neoplasms
-
Xing M, Vasko V, Tallini G, et al. BRAF T1796A transversion mutation in various thyroid neoplasms. J Clin Endocrinol Metab 2004;89:1365-8.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1365-1368
-
-
Xing, M.1
Vasko, V.2
Tallini, G.3
-
12
-
-
10744222003
-
BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas
-
Nikiforova MN, Kimura ET, Gandhi M, et al. BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas. J Clin Endocrinol Metab 2003;88:5399-404.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5399-5404
-
-
Nikiforova, M.N.1
Kimura, E.T.2
Gandhi, M.3
-
13
-
-
0141453014
-
Clinical implication of hot spot BRAF mutation, V599E, in papillary thyroid cancers
-
Namba H, Nakashima M, Hayashi T, et al. Clinical implication of hot spot BRAF mutation, V599E, in papillary thyroid cancers. J Clin Endocrinol Metab 2003;88:4393-7.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4393-4397
-
-
Namba, H.1
Nakashima, M.2
Hayashi, T.3
-
14
-
-
28744442816
-
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer
-
Epub 2005 September 20
-
Xing M, Westra WH, Tufano RP, et al. BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer. J Clin Endocrinol Metab 2005;90:6373-9. Epub 2005 September 20.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 6373-6379
-
-
Xing, M.1
Westra, W.H.2
Tufano, R.P.3
-
15
-
-
21244457181
-
BRAF mutation in thyroid cancer
-
Xing M. BRAF mutation in thyroid cancer. Endocr Relat Cancer 2005;12:245-62.
-
(2005)
Endocr Relat Cancer
, vol.12
, pp. 245-262
-
-
Xing, M.1
-
16
-
-
12144289677
-
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
-
Wan PT, Garnett MJ, Roe SM, et al. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 2004;116:855-67.
-
(2004)
Cell
, vol.116
, pp. 855-867
-
-
Wan, P.T.1
Garnett, M.J.2
Roe, S.M.3
-
17
-
-
85047691154
-
Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer
-
Ciampi R, Knauf JA, Kerler R, et al. Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer. J Clin Invest 2005;115:94-101.
-
(2005)
J Clin Invest
, vol.115
, pp. 94-101
-
-
Ciampi, R.1
Knauf, J.A.2
Kerler, R.3
-
18
-
-
20144387455
-
The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells
-
Melillo RM, Castellone MD, Guarino V, et al. The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells. J Clin Invest 2005;115:1068-81.
-
(2005)
J Clin Invest
, vol.115
, pp. 1068-1081
-
-
Melillo, R.M.1
Castellone, M.D.2
Guarino, V.3
-
19
-
-
16844367605
-
Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells
-
Mitsutake N, Knauf JA, Mitsutake S, Mesa C, Jr., Zhang L, Fagin JA. Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells. Cancer Res 2005;65:2465-73.
-
(2005)
Cancer Res
, vol.65
, pp. 2465-2473
-
-
Mitsutake, N.1
Knauf, J.A.2
Mitsutake, S.3
Mesa Jr., C.4
Zhang, L.5
Fagin, J.A.6
-
20
-
-
20144372793
-
Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation
-
Knauf JA, Ma X, Smith EP, et al. Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation. Cancer Res 2005;65:4238-45.
-
(2005)
Cancer Res
, vol.65
, pp. 4238-4245
-
-
Knauf, J.A.1
Ma, X.2
Smith, E.P.3
-
23
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
Wilhelm SM, Carter C, Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004;64:7099-109.
-
(2004)
Cancer Res
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
-
24
-
-
20044382799
-
Phase I clinical and pharmacokinetic study of the novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
-
Strumberg D, Richly H, Hilger RA, et al. Phase I clinical and pharmacokinetic study of the novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol 2005;23:965-72.
-
(2005)
J Clin Oncol
, vol.23
, pp. 965-972
-
-
Strumberg, D.1
Richly, H.2
Hilger, R.A.3
-
25
-
-
0024419333
-
Characterization of tumor necrosis factor-α receptors in human and rat thyroid cells and regulation of the receptors by thyrotropin
-
Pang XP, Hershman JM, Chung M, et al. Characterization of tumor necrosis factor-α receptors in human and rat thyroid cells and regulation of the receptors by thyrotropin. Endocrinology 1989;125:1783-8.
-
(1989)
Endocrinology
, vol.125
, pp. 1783-1788
-
-
Pang, X.P.1
Hershman, J.M.2
Chung, M.3
-
26
-
-
9844237006
-
Cytokine production by a new undifferentiated human thyroid carcinoma cell line, FB-1
-
Fiore L, Pollina LE, Fontanini G, et al. Cytokine production by a new undifferentiated human thyroid carcinoma cell line, FB-1. J Clin Endocrinol Metab 1997;82:4094-100.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 4094-4100
-
-
Fiore, L.1
Pollina, L.E.2
Fontanini, G.3
-
27
-
-
0029823530
-
Antineoplastic activity of Taxol against human anaplastic thyroid carcinoma cell lines in vitro and in vivo
-
Ain KB, Tofiq S, Taylor KD. Antineoplastic activity of Taxol against human anaplastic thyroid carcinoma cell lines in vitro and in vivo. J Clin Endocrinol Metab 1996;81:3650-3.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 3650-3653
-
-
Ain, K.B.1
Tofiq, S.2
Taylor, K.D.3
-
28
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
Fagin JA, Matsuo K, Karmakar A, Chen DL, Tang SH, Koeffler HP. High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 1993;91:179-84.
-
(1993)
J Clin Invest
, vol.91
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Chen, D.L.4
Tang, S.H.5
Koeffler, H.P.6
-
29
-
-
0026575904
-
Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland
-
Ito T, Seyama T, Mizuno T, et al. Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland. Cancer Res 1992;52:1369-71.
-
(1992)
Cancer Res
, vol.52
, pp. 1369-1371
-
-
Ito, T.1
Seyama, T.2
Mizuno, T.3
-
30
-
-
0028556807
-
Long-term culture and functional characterization of follicular cells from adult normal human thyroids
-
Curcio F, Ambesi-Impiombato FS, Perrella G, Coon HG. Long-term culture and functional characterization of follicular cells from adult normal human thyroids. Proc Natl Acad Sci U S A 1994;91:9004-8.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 9004-9008
-
-
Curcio, F.1
Ambesi-Impiombato, F.S.2
Perrella, G.3
Coon, H.G.4
-
31
-
-
0141816881
-
Suppression of BRAF (V599E) in human melanoma abrogates transformation
-
Hingorani SR, Jacobetz MA, Robertson GP, Herlyn M, Tuveson DA. Suppression of BRAF (V599E) in human melanoma abrogates transformation. Cancer Res 2003;63:5198-202.
-
(2003)
Cancer Res
, vol.63
, pp. 5198-5202
-
-
Hingorani, S.R.1
Jacobetz, M.A.2
Robertson, G.P.3
Herlyn, M.4
Tuveson, D.A.5
-
32
-
-
0027057589
-
Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections
-
Cattoretti G, Becker MH, Key G, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 1992;168:357-63.
-
(1992)
J Pathol
, vol.168
, pp. 357-363
-
-
Cattoretti, G.1
Becker, M.H.2
Key, G.3
-
33
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
-
(1992)
J Cell Biol
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
34
-
-
10344258041
-
Targeting the mitogen-activated protein kinase cascade to treat cancer
-
Sebolt-Leopold JS, Herrera R. Targeting the mitogen-activated protein kinase cascade to treat cancer. Nat Rev Cancer 2004;4:937-47.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 937-947
-
-
Sebolt-Leopold, J.S.1
Herrera, R.2
-
35
-
-
27244457769
-
Raf: A strategic target for therapeutic development against cancer
-
Beeram M, Patnaik A, Rowinsky EK. Raf: a strategic target for therapeutic development against cancer. J Clin Oncol 2005;23:6771-90.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6771-6790
-
-
Beeram, M.1
Patnaik, A.2
Rowinsky, E.K.3
-
36
-
-
16844362816
-
Mutant V599E B-Raf regulates growth and vascular development of malignant melanoma tumors
-
Sharma A, Trivedi NR, Zimmerman MA, Tuveson DA, Smith CD, Robertson GP. Mutant V599E B-Raf regulates growth and vascular development of malignant melanoma tumors. Cancer Res 2005;65:2412-21.
-
(2005)
Cancer Res
, vol.65
, pp. 2412-2421
-
-
Sharma, A.1
Trivedi, N.R.2
Zimmerman, M.A.3
Tuveson, D.A.4
Smith, C.D.5
Robertson, G.P.6
-
37
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek J, Akinc A, Bramlage B, et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 2004;432:173-8.
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
-
38
-
-
17644383664
-
Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS
-
Raoul C, Abbas-Terki T, Bensadoun JC, et al. Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS. Nat Med 2005;11:423-8.
-
(2005)
Nat Med
, vol.11
, pp. 423-428
-
-
Raoul, C.1
Abbas-Terki, T.2
Bensadoun, J.C.3
-
39
-
-
9244222261
-
Targeted cancer therapy
-
Sawyers C. Targeted cancer therapy. Nature 2004;432:294-7.
-
(2004)
Nature
, vol.432
, pp. 294-297
-
-
Sawyers, C.1
-
40
-
-
27144443099
-
Drug discovery: Playing dirty
-
Frantz S. Drug discovery: playing dirty. Nature 2005;437:942-3.
-
(2005)
Nature
, vol.437
, pp. 942-943
-
-
Frantz, S.1
|