-
1
-
-
0025312728
-
A genetic model for colorectal tumourigenesis
-
Fearon ER, Vogelstein B. A genetic model for colorectal tumourigenesis. Cell 1990; 61: 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
2
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87: 159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
3
-
-
0030818746
-
The interactions of APC, E-cadherin and β-catenin in tumour development and progression
-
Ilyas M, Tomlinson IPM. The interactions of APC, E-cadherin and β-catenin in tumour development and progression. J Pathol 1997; 182: 128-137.
-
(1997)
J Pathol
, vol.182
, pp. 128-137
-
-
Ilyas, M.1
Tomlinson, I.P.M.2
-
4
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
-
Behrens J, Jerchow BA, Würtele M, et al. Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β. Science 1998; 280: 596-599.
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Würtele, M.3
-
5
-
-
0032483439
-
Identification of c-myc as a target of the APC pathway
-
He TC, Sparks AB, Rago C, et al. Identification of c-myc as a target of the APC pathway. Science 1998; 281: 1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
-
6
-
-
0031806044
-
The molecular role of myc in growth and transformation: Recent discoveries lead to new insights
-
Facchini LM, Penn LZ. The molecular role of myc in growth and transformation: recent discoveries lead to new insights. FASEB J 1998; 12: 633-651.
-
(1998)
FASEB J
, vol.12
, pp. 633-651
-
-
Facchini, L.M.1
Penn, L.Z.2
-
7
-
-
0033613854
-
Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-Myc
-
Wu KJ, Polack A, Dalla-Favera R. Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-Myc. Science 1999; 283: 676-679.
-
(1999)
Science
, vol.283
, pp. 676-679
-
-
Wu, K.J.1
Polack, A.2
Dalla-Favera, R.3
-
8
-
-
0033548034
-
Unlimited mileage from lelomerase?
-
Lange de T, Depinho RA. Unlimited mileage from lelomerase? Science 1999; 283: 947-949.
-
(1999)
Science
, vol.283
, pp. 947-949
-
-
De Lange, T.1
Depinho, R.A.2
-
9
-
-
0024376173
-
Ras oncogenes in human colon cancer: A review
-
Bos JL. Ras oncogenes in human colon cancer: a review. Cancer Res 1989; 49: 4682-4686.
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4686
-
-
Bos, J.L.1
-
10
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone MH, Roy N, Stennicke HR, et al. Regulation of cell death protease caspase-9 by phosphorylation. Science 1998; 282: 1318-1321.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
-
12
-
-
0033119801
-
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O, McCormick F. β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999; 398: 422-426.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
13
-
-
0030592522
-
Deleted in colorectal cancer (DCC) encodes a netrin receptor
-
Keino-Masu K, Masu M, Hinck L, et al. Deleted in colorectal cancer (DCC) encodes a netrin receptor. Cell 1996; 87: 175-185.
-
(1996)
Cell
, vol.87
, pp. 175-185
-
-
Keino-Masu, K.1
Masu, M.2
Hinck, L.3
-
14
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Hoque ATMS, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996; 271: 350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.M.S.3
-
15
-
-
15844390729
-
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
-
Thiagalingam S, Lengauer C, Leach FS, et al. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nature 1996; 13: 343-346.
-
(1996)
Nature
, vol.13
, pp. 343-346
-
-
Thiagalingam, S.1
Lengauer, C.2
Leach, F.S.3
-
16
-
-
0030460085
-
Cancer gets mad: DPC4 and other TGFβ pathway genes in human cancer
-
Moskaluk CA, Kern SE. Cancer gets mad: DPC4 and other TGFβ pathway genes in human cancer. Biochim Biophys Acta 1996; 1288: M31-M33.
-
(1996)
Biochim Biophys Acta
, vol.1288
-
-
Moskaluk, C.A.1
Kern, S.E.2
-
17
-
-
16044369574
-
MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
Eppert K, Scherer SW, Ozcelik H, et al. MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 1996; 86: 543-552.
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
Scherer, S.W.2
Ozcelik, H.3
-
18
-
-
2642605344
-
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
-
de Caestecker MP, Parks WT, Frank CJ, et al. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev 1998; 12: 1587-1592.
-
(1998)
Genes Dev
, vol.12
, pp. 1587-1592
-
-
De Caestecker, M.P.1
Parks, W.T.2
Frank, C.J.3
-
19
-
-
0028785603
-
Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
-
Parsons R, Myeroff LL, Liu B, et al. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res 1995; 55: 5548-5550.
-
(1995)
Cancer Res
, vol.55
, pp. 5548-5550
-
-
Parsons, R.1
Myeroff, L.L.2
Liu, B.3
-
20
-
-
0030237476
-
p53 - Integrating the complexity
-
Hall PA, Meek D, Lane DP. p53 - integrating the complexity. J Pathol 1996; 180: 1-5.
-
(1996)
J Pathol
, vol.180
, pp. 1-5
-
-
Hall, P.A.1
Meek, D.2
Lane, D.P.3
-
21
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88: 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
22
-
-
0032931517
-
The p53 pathway
-
Prives C, Hall PA. The p53 pathway. J Pathol 1999; 187: 112-126.
-
(1999)
J Pathol
, vol.187
, pp. 112-126
-
-
Prives, C.1
Hall, P.A.2
-
23
-
-
0031048236
-
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
-
Loda M, Cukor B, Tam SW, et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nature Med 1997; 3: 231-234.
-
(1997)
Nature Med
, vol.3
, pp. 231-234
-
-
Loda, M.1
Cukor, B.2
Tam, S.W.3
-
25
-
-
0032189630
-
Drosophila CBP represses the transciption factor TCF to antagonize Wingless signalling
-
Waltzer L, Bienz M. Drosophila CBP represses the transciption factor TCF to antagonize Wingless signalling. Nature 1998; 395: 521-525.
-
(1998)
Nature
, vol.395
, pp. 521-525
-
-
Waltzer, L.1
Bienz, M.2
-
26
-
-
0032522978
-
Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene
-
Sevignani C, Wlodarski P, Kirillova J, et al. Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene. J Clin Invest 1998; 101: 1572-1580.
-
(1998)
J Clin Invest
, vol.101
, pp. 1572-1580
-
-
Sevignani, C.1
Wlodarski, P.2
Kirillova, J.3
-
27
-
-
0027138093
-
K-ras mutations in putative preneoplastic lesions in human colon
-
Pretlow TP, Brasitus TA, Fulton NC, Cheyer C, Kaplan EL. K-ras mutations in putative preneoplastic lesions in human colon. J Natl Cancer Inst 1993; 85: 2004-2007.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 2004-2007
-
-
Pretlow, T.P.1
Brasitus, T.A.2
Fulton, N.C.3
Cheyer, C.4
Kaplan, E.L.5
-
28
-
-
17144464406
-
Aberrant crypt foci of the colon as precursors of adenoma and cancer
-
Takayama T, Katsuki S, Takahashi Y, et al. Aberrant crypt foci of the colon as precursors of adenoma and cancer. N Engl J Med 1998; 339: 1277-1284.
-
(1998)
N Engl J Med
, vol.339
, pp. 1277-1284
-
-
Takayama, T.1
Katsuki, S.2
Takahashi, Y.3
-
29
-
-
0030333066
-
The conceptual and practical impact of Ki-ras mutation in colorectal neoplasia
-
Arends JW, Bosman FT. The conceptual and practical impact of Ki-ras mutation in colorectal neoplasia. J Pathol 1996; 180: 355-356.
-
(1996)
J Pathol
, vol.180
, pp. 355-356
-
-
Arends, J.W.1
Bosman, F.T.2
-
30
-
-
0027973077
-
Molecular determinants of dysplasia in colorectal lesions
-
Jen J, Powell SM, Papadopoulos N, et al. Molecular determinants of dysplasia in colorectal lesions. Cancer Res 1994; 54: 5523-5526.
-
(1994)
Cancer Res
, vol.54
, pp. 5523-5526
-
-
Jen, J.1
Powell, S.M.2
Papadopoulos, N.3
-
31
-
-
0028062973
-
Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons
-
Smith AJ, Stern HS, Penner M, et al. Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons. Cancer Res. 1994; 54: 5527-5530.
-
(1994)
Cancer Res.
, vol.54
, pp. 5527-5530
-
-
Smith, A.J.1
Stern, H.S.2
Penner, M.3
-
32
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Ape genes
-
Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF, Taketo MM. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Ape genes. Cell 1998; 92: 645-656.
-
(1998)
Cell
, vol.92
, pp. 645-656
-
-
Takaku, K.1
Oshima, M.2
Miyoshi, H.3
Matsui, M.4
Seldin, M.F.5
Taketo, M.M.6
-
33
-
-
0033011006
-
Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog
-
Tomlinson I, Bodmer W. Selection, the mutation rate and cancer: ensuring that the tail does not wag the dog. Nature Med 1999; 5: 11-12.
-
(1999)
Nature Med
, vol.5
, pp. 11-12
-
-
Tomlinson, I.1
Bodmer, W.2
-
35
-
-
0028792347
-
Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy
-
Clarke AR, Cummings MC, Harrison DJ. Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy. Oncogene 1995; 11: 1913-1920.
-
(1995)
Oncogene
, vol.11
, pp. 1913-1920
-
-
Clarke, A.R.1
Cummings, M.C.2
Harrison, D.J.3
-
36
-
-
0032146118
-
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability
-
Cunningham JM, Christensen ER, Tester DJ, et al. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. Cancer Res 1998; 58: 3455-3460.
-
(1998)
Cancer Res
, vol.58
, pp. 3455-3460
-
-
Cunningham, J.M.1
Christensen, E.R.2
Tester, D.J.3
-
37
-
-
0029842219
-
In situ hybridization and flow cytometric analysis of colorectal tumours suggests two routes of tumourigenesis characterized by gain of chromosome 7 or loss of chromosomes 17 and 18
-
Herbergs J, Hopman AHN, de Bruïne AP, Ramaekers FCS, Arends JW. In situ hybridization and flow cytometric analysis of colorectal tumours suggests two routes of tumourigenesis characterized by gain of chromosome 7 or loss of chromosomes 17 and 18. J Pathol 1996; 179: 243-247.
-
(1996)
J Pathol
, vol.179
, pp. 243-247
-
-
Herbergs, J.1
Hopman, A.H.N.2
De Bruïne, A.P.3
Ramaekers, F.C.S.4
Arends, J.W.5
-
38
-
-
0342977695
-
Deletion of 1p36 as a primary chromosomal aberration in intestinal tumorigenesis
-
Bardi G, Pandis N, Fenger C, Kronborg O, Bomme L, Heim S. Deletion of 1p36 as a primary chromosomal aberration in intestinal tumorigenesis. Cancer Res 1993; 10: 190-196.
-
(1993)
Cancer Res
, vol.10
, pp. 190-196
-
-
Bardi, G.1
Pandis, N.2
Fenger, C.3
Kronborg, O.4
Bomme, L.5
Heim, S.6
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