메뉴 건너뛰기




Volumn 22, Issue 6, 2003, Pages 1325-1335

GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction

Author keywords

Co localization; GRIM 19; Interaction; Repression; Stat3

Indexed keywords

GENE PRODUCT; STAT3 PROTEIN;

EID: 0037451235     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg135     Document Type: Article
Times cited : (204)

References (54)
  • 1
    • 0034657958 scopus 로고    scopus 로고
    • Roles of STAT3 defined in tissue-specific gene targeting
    • Akira, S. (2000) Roles of STAT3 defined in tissue-specific gene targeting. Oncogene, 19, 2607-2611.
    • (2000) Oncogene , vol.19 , pp. 2607-2611
    • Akira, S.1
  • 2
    • 0028303977 scopus 로고
    • Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
    • Akira, S. et al. (1994) Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell, 77, 63-71.
    • (1994) Cell , vol.77 , pp. 63-71
    • Akira, S.1
  • 3
    • 0034721920 scopus 로고    scopus 로고
    • Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-β and retinoic acid combination, using a genetic approach
    • Angell, J.E., Lindner, D.J., Shapiro, P.S., Hofmann, E.R. and Kalvakolanu, D.V. (2000) Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-β and retinoic acid combination, using a genetic approach. J. Biol. Chem., 275, 33416-33426.
    • (2000) J. Biol. Chem. , vol.275 , pp. 33416-33426
    • Angell, J.E.1    Lindner, D.J.2    Shapiro, P.S.3    Hofmann, E.R.4    Kalvakolanu, D.V.5
  • 4
    • 0032499801 scopus 로고    scopus 로고
    • Three-dimensional structure of the Stat3b homodimer bound to DNA
    • Becker, S., Groner, B. and Müller, C.W. (1998) Three-dimensional structure of the Stat3b homodimer bound to DNA. Nature, 394, 145-151.
    • (1998) Nature , vol.394 , pp. 145-151
    • Becker, S.1    Groner, B.2    Müller, C.W.3
  • 8
    • 0029916933 scopus 로고    scopus 로고
    • Activation and association of Stat3 with Src in v-Src-transfromed cell lines
    • Cao, X., Tay, A., Guy, G.R. and Tan, Y.H. (1996) Activation and association of Stat3 with Src in v-Src-transfromed cell lines. Mol. Cell. Biol., 16, 1595-1603.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1595-1603
    • Cao, X.1    Tay, A.2    Guy, G.R.3    Tan, Y.H.4
  • 9
    • 0032984589 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
    • Catlett-Falcone, R. et al. (1999) Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity, 10, 105-115.
    • (1999) Immunity , vol.10 , pp. 105-115
    • Catlett-Falcone, R.1
  • 10
    • 0032577678 scopus 로고    scopus 로고
    • Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
    • Chen, X., Vinkemeier, U., Zhao, Y., Jeruzalmi, D., Darnell, J.E., Jr and Kuriyan, J. (1998) Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell, 93, 827-839.
    • (1998) Cell , vol.93 , pp. 827-839
    • Chen, X.1    Vinkemeier, U.2    Zhao, Y.3    Jeruzalmi, D.4    Darnell J.E., Jr.5    Kuriyan, J.6
  • 11
    • 0030725378 scopus 로고    scopus 로고
    • Specific inhibition of Stat3 signal transduction by PIAS3
    • Chung, C.D., Liao, J., Liu, B., Rao, X., Jay, P., Berta, P. and Shuai, K. (1997) Specific inhibition of Stat3 signal transduction by PIAS3. Science, 278, 1803-1805.
    • (1997) Science , vol.278 , pp. 1803-1805
    • Chung, C.D.1    Liao, J.2    Liu, B.3    Rao, X.4    Jay, P.5    Berta, P.6    Shuai, K.7
  • 12
    • 0033198919 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
    • D'Amours, D., Desnoyers, S., D'Silva, I. and Poirier, G.G. (1999) Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J., 342, 249-268.
    • (1999) Biochem. J. , vol.342 , pp. 249-268
    • D'Amours, D.1    Desnoyers, S.2    D'Silva, I.3    Poirier, G.G.4
  • 13
    • 0028817880 scopus 로고
    • Jak-STAT signaling induced by the v-abl oncogene
    • Danial, N.N., Pernis, A. and Rothman, P.B. (1995) Jak-STAT signaling induced by the v-abl oncogene. Science, 269, 1875-1877.
    • (1995) Science , vol.269 , pp. 1875-1877
    • Danial, N.N.1    Pernis, A.2    Rothman, P.B.3
  • 14
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell, J.E., Jr, Kerr, I.M. and Stark, G.R. (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science, 264, 1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell J.E., Jr.1    Kerr, I.M.2    Stark, G.R.3
  • 16
    • 0030839112 scopus 로고    scopus 로고
    • A new protein containing an SH2 domain that inhibits JAK kinases
    • Endo, T.A. et al. (1997) A new protein containing an SH2 domain that inhibits JAK kinases. Nature, 387, 921-924.
    • (1997) Nature , vol.387 , pp. 921-924
    • Endo, T.A.1
  • 17
    • 0035914435 scopus 로고    scopus 로고
    • GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I)
    • Fearnley, I.M., Carroll, J., Shannon, R.J., Runswick, M.J., Walker, J.E. and Hirst, J. (2001) GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I). J. Biol. Chem., 276, 38345-38348.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38345-38348
    • Fearnley, I.M.1    Carroll, J.2    Shannon, R.J.3    Runswick, M.J.4    Walker, J.E.5    Hirst, J.6
  • 18
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp 130: Involvement of STAT3 in anti-apoptosis
    • Fukada, T., Hibi, M., Yamanaka, Y., Takahashi-Tezuka, M., Fujitani, Y., Yamaguchi, T., Nakajima, K. and Hirano, T. (1996) Two signals are necessary for cell proliferation induced by a cytokine receptor gp 130: involvement of STAT3 in anti-apoptosis. Immunity, 5, 449-460.
    • (1996) Immunity , vol.5 , pp. 449-460
    • Fukada, T.1    Hibi, M.2    Yamanaka, Y.3    Takahashi-Tezuka, M.4    Fujitani, Y.5    Yamaguchi, T.6    Nakajima, K.7    Hirano, T.8
  • 19
    • 12944272024 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo
    • Grandis, J.R. et al. (2000) Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc. Natl Acad. Sci. USA, 97, 4227-4232.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4227-4232
    • Grandis, J.R.1
  • 20
    • 0029972194 scopus 로고    scopus 로고
    • The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase
    • Haspel, R.L., Salditt-Georgieff, M. and Darnell, J.E., Jr (1996) The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J., 15, 6262-6268.
    • (1996) EMBO J. , vol.15 , pp. 6262-6268
    • Haspel, R.L.1    Salditt-Georgieff, M.2    Darnell J.E., Jr.3
  • 21
    • 0032168152 scopus 로고    scopus 로고
    • Interleukin-6-type cytokine signaling through the gp130/Jak/STAT pathway
    • Heinrich, P.C., Behrmann, I., Muller-Newen, G., Schaper, F. and Graeve,L. (1998) Interleukin-6-type cytokine signaling through the gp130/Jak/ STAT pathway. Biochem. J., 334, 297-314.
    • (1998) Biochem. J. , vol.334 , pp. 297-314
    • Heinrich, P.C.1    Behrmann, I.2    Muller-Newen, G.3    Schaper, F.4    Graeve, L.5
  • 23
    • 0029909271 scopus 로고    scopus 로고
    • Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex
    • Horvath, C.M., Stark, G.R., Kerr, I.M. and Darnell, J.E., Jr (1996) Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex. Mol. Cell. Biol., 16, 6957-6964.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6957-6964
    • Horvath, C.M.1    Stark, G.R.2    Kerr, I.M.3    Darnell J.E., Jr.4
  • 24
    • 0036440556 scopus 로고    scopus 로고
    • Characterization of monoclonal antibodies against GRIM-19, a novel IFN-β and retinoic acid-activated regulator of cell death
    • Hu, J., Angell, J.E., Zhang, J., Ma, X., Seo, T., Raha, A., Hayashi, J., Choe, J. and Kalvakolanu, D.V. (2002) Characterization of monoclonal antibodies against GRIM-19, a novel IFN-β and retinoic acid-activated regulator of cell death. J. Interferon Cytokine Res., 22, 1017-1026.
    • (2002) J. Interferon Cytokine Res. , vol.22 , pp. 1017-1026
    • Hu, J.1    Angell, J.E.2    Zhang, J.3    Ma, X.4    Seo, T.5    Raha, A.6    Hayashi, J.7    Choe, J.8    Kalvakolanu, D.V.9
  • 25
    • 0035313701 scopus 로고    scopus 로고
    • The Stat family in cytokine signaling
    • Ihle, J.N. (2001) The Stat family in cytokine signaling. Curr. Opin. Cell Biol., 13, 211-217.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 211-217
    • Ihle, J.N.1
  • 26
    • 0032542211 scopus 로고    scopus 로고
    • Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)
    • Jain, N., Zhang, T., Fong, S.L., Lim, C.P. and Cao, X. (1998) Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK). Oncogene, 17, 3157-3167.
    • (1998) Oncogene , vol.17 , pp. 3157-3167
    • Jain, N.1    Zhang, T.2    Fong, S.L.3    Lim, C.P.4    Cao, X.5
  • 27
    • 0033588229 scopus 로고    scopus 로고
    • Protein kinase Cδ associates with and phosphorylates Stat3 in an interleukin-6-dependent manner
    • Jain, N., Zhang, T., Kee, W.H., Li, W. and Cao, X. (1999) Protein kinase Cδ associates with and phosphorylates Stat3 in an interleukin-6-dependent manner. J. Biol. Chem., 274, 24392-24400.
    • (1999) J. Biol. Chem. , vol.274 , pp. 24392-24400
    • Jain, N.1    Zhang, T.2    Kee, W.H.3    Li, W.4    Cao, X.5
  • 28
    • 0000413462 scopus 로고    scopus 로고
    • Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway
    • Kim, T.K. and Maniatis, T. (1996) Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway. Science, 273, 1717-1719.
    • (1996) Science , vol.273 , pp. 1717-1719
    • Kim, T.K.1    Maniatis, T.2
  • 29
    • 0034029917 scopus 로고    scopus 로고
    • Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics
    • Lai, C.H., Chou, C.Y., Ch'ang, L.Y., Liu, C.S. and Lin, W. (2000) Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. Genome Res., 10, 703-713.
    • (2000) Genome Res. , vol.10 , pp. 703-713
    • Lai, C.H.1    Chou, C.Y.2    Ch'ang, L.Y.3    Liu, C.S.4    Lin, W.5
  • 30
    • 0028079763 scopus 로고
    • Vitamin A, differentiation and cancer
    • Love, J.M. and Gudas, L.J. (1994) Vitamin A, differentiation and cancer. Curr. Opin. Cell Biol., 6, 825-831.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 825-831
    • Love, J.M.1    Gudas, L.J.2
  • 32
    • 0025819331 scopus 로고
    • CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells
    • Metzelaar, M.J., Wijngaard, P.L., Peters, P.J., Sixma, J.J., Nieuwenhuis, H.K. and Clevers, H.C. (1991) CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells. J. Biol. Chem., 266, 3239-3245.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3239-3245
    • Metzelaar, M.J.1    Wijngaard, P.L.2    Peters, P.J.3    Sixma, J.J.4    Nieuwenhuis, H.K.5    Clevers, H.C.6
  • 33
    • 0036055754 scopus 로고    scopus 로고
    • Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3
    • Meyer, T., Gavenis, K. and Vinkemeier, U. (2002) Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3. Exp. Cell Res., 272, 45-55.
    • (2002) Exp. Cell Res. , vol.272 , pp. 45-55
    • Meyer, T.1    Gavenis, K.2    Vinkemeier, U.3
  • 34
    • 0029030937 scopus 로고
    • EEA1, an early endosome-associated protein. EEA1 is a conserved α-helical peripheral membrane protein flanked by cysteine 'fingers' and contains a calmodulin-binding IQ motif
    • Mu, F.T. et al. (1995) EEA1, an early endosome-associated protein. EEA1 is a conserved α-helical peripheral membrane protein flanked by cysteine 'fingers' and contains a calmodulin-binding IQ motif. J. Biol. Chem. 270, 13503-13511.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13503-13511
    • Mu, F.T.1
  • 35
    • 0030755934 scopus 로고    scopus 로고
    • Structure and function of a new STAT-induced STAT inhibitor
    • Naka, T. et al. (1997) Structure and function of a new STAT-induced STAT inhibitor. Nature, 387, 924-929.
    • (1997) Nature , vol.387 , pp. 924-929
    • Naka, T.1
  • 36
    • 0019877801 scopus 로고
    • Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples
    • Olmsted, J.B. (1981) Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples. J. Biol. Chem., 256, 11955-11957.
    • (1981) J. Biol. Chem. , vol.256 , pp. 11955-11957
    • Olmsted, J.B.1
  • 37
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002. New surprises in the Jak/STAT pathway
    • O'Shea, J.J., Gadina, M. and Schreiber, R.D. (2002) Cytokine signaling in 2002. New surprises in the Jak/STAT pathway. Cell, 109, S121-S131.
    • (2002) Cell , vol.109
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 38
    • 0027496114 scopus 로고
    • A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
    • Sadowski, H.B., Shuai, K., Darnell, J.E., Jr and Gilman, M.Z. (1993) A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science, 261, 1739-1743.
    • (1993) Science , vol.261 , pp. 1739-1743
    • Sadowski, H.B.1    Shuai, K.2    Darnell J.E., Jr.3    Gilman, M.Z.4
  • 39
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler, C. and Darnell, J.E. (1995) Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem., 64, 621-651.
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell, J.E.2
  • 40
    • 0035834658 scopus 로고    scopus 로고
    • Endofin, an endosomal FYVE domain protein
    • Seet, L.F. and Hong, W. (2001) Endofin, an endosomal FYVE domain protein. J. Biol. Chem., 276, 42445-42454.
    • (2001) J. Biol. Chem. , vol.276 , pp. 42445-42454
    • Seet, L.F.1    Hong, W.2
  • 42
    • 0030792590 scopus 로고    scopus 로고
    • A family of cytokine-inducible inhibitors of signaling
    • Starr, R. et al. (1997) A family of cytokine-inducible inhibitors of signaling. Nature, 387, 917-921.
    • (1997) Nature , vol.387 , pp. 917-921
    • Starr, R.1
  • 45
    • 0031953831 scopus 로고    scopus 로고
    • Stat3 activation by Src induces specific gene regulation and is required for cell transformation
    • Turkson, J., Bowman, T., Garcia, R., Caldenhoven, E., De Groot, R.P. and Jove, R. (1998) Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol. Cell. Biol., 18, 2545-2552.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2545-2552
    • Turkson, J.1    Bowman, T.2    Garcia, R.3    Caldenhoven, E.4    De Groot, R.P.5    Jove, R.6
  • 46
    • 0034082217 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling pathways
    • Yasukawa, H., Sasaki, A. and Yoshimura, A. (2000) Negative regulation of cytokine signaling pathways. Annu. Rev. Immunol., 18, 143-164.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 143-164
    • Yasukawa, H.1    Sasaki, A.2    Yoshimura, A.3
  • 47
    • 0029014206 scopus 로고
    • A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
    • Yoshimura, A., Ohkubo, T., Kiguchi, T., Jenkins, N.A., Gilbert, D.J., Copeland, N.G., Hara, T. and Miyajima, A. (1995) A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J., 14, 2816-2826.
    • (1995) EMBO J. , vol.14 , pp. 2816-2826
    • Yoshimura, A.1    Ohkubo, T.2    Kiguchi, T.3    Jenkins, N.A.4    Gilbert, D.J.5    Copeland, N.G.6    Hara, T.7    Miyajima, A.8
  • 48
    • 0029069540 scopus 로고
    • Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
    • Yu, C.-L., Meyer, D.J., Campbell, G.S., Larner, A.C., Carter-Su, C., Schwartz, J. and Jove, R. (1995) Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science, 269, 81-83.
    • (1995) Science , vol.269 , pp. 81-83
    • Yu, C.-L.1    Meyer, D.J.2    Campbell, G.S.3    Larner, A.C.4    Carter-Su, C.5    Schwartz, J.6    Jove, R.7
  • 49
    • 0033834679 scopus 로고    scopus 로고
    • The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6
    • Zhang, T., Kee, W.H., Seow, K.T., Fung, W. and Cao, X. (2000) The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6. Mol. Cell. Biol., 20, 7132-7139.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7132-7139
    • Zhang, T.1    Kee, W.H.2    Seow, K.T.3    Fung, W.4    Cao, X.5
  • 50
    • 0037124037 scopus 로고    scopus 로고
    • Interdomain interaction of Stat3 regulates its SH2 domain-mediated receptor binding activity
    • Zhang, T., Seow, K.T., Ong, C.T. and Cao, X. (2002) Interdomain interaction of Stat3 regulates its SH2 domain-mediated receptor binding activity. J. Biol. Chem., 277, 17556-17563.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17556-17563
    • Zhang, T.1    Seow, K.T.2    Ong, C.T.3    Cao, X.4
  • 51
    • 0032845125 scopus 로고    scopus 로고
    • Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation
    • Zhang, X., Wrzeszczynska, M.H., Horvath, C.M. and Darnell, J.E., Jr (1999) Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation. Mol. Cell. Biol., 19, 7138-7146.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7138-7146
    • Zhang, X.1    Wrzeszczynska, M.H.2    Horvath, C.M.3    Darnell J.E., Jr.4
  • 52
    • 0028284762 scopus 로고
    • Stat3 and Stat4: Members of the family of signal transducers and activators of transcription
    • Zhong, Z., Wen, Z. and Darnell, J.E., Jr (1994a) Stat3 and Stat4: members of the family of signal transducers and activators of transcription. Proc. Natl Acad. Sci. USA, 91, 4806-4810.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4806-4810
    • Zhong, Z.1    Wen, Z.2    Darnell J.E., Jr.3
  • 53
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in respone to epidermal growth factor and interleukin-6
    • Zhong, Z., Wen, Z. and Darnell, J.E., Jr (1994b) Stat3: a STAT family member activated by tyrosine phosphorylation in respone to epidermal growth factor and interleukin-6. Science, 264, 95-98.
    • (1994) Science , vol.264 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell J.E., Jr.3
  • 54
    • 0033534562 scopus 로고    scopus 로고
    • Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNγ-mediated signaling
    • Zhu, M.-H., John, S., Berg, M. and Leonard, W.J. (1999) Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNγ-mediated signaling. Cell, 96, 121-130.
    • (1999) Cell , vol.96 , pp. 121-130
    • Zhu, M.-H.1    John, S.2    Berg, M.3    Leonard, W.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.