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Volumn 9, Issue 8, 2004, Pages 734-755

Emerging experimental therapeutics for bipolar disorder: Insights from the molecular and cellular actions of current mood stabilizers

Author keywords

Depression; Mania; Manic depressive illness; Neurotrophic factors; PAP phosphatase; Pharmacology; Pramipexole; Valproic acid; Zinc

Indexed keywords

2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ADENOSINE RECEPTOR; ADENYLATE CYCLASE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; AR A 014418; ARACHIDONIC ACID; CARBAMAZEPINE; CYCLIC AMP; FRUCTOSE BISPHOSPHATASE; GLYCOGEN SYNTHASE KINASE 3; HISTONE DEACETYLASE; INOSITOL PHOSPHATE; INOSITOL POLYPHOSPHATE; LITHIUM; MAGNESIUM; MALEIMIDE DERIVATIVE; NEUROLEPTIC AGENT; NEUROTROPHIC FACTOR; NUCLEOTIDASE; PAULLONE DERIVATIVE; PEPTIDE DERIVATIVE; PHOSPHOGLUCOMUTASE; PROTEIN KINASE C; PYRROLE DERIVATIVE; SB 21676; SODIUM CHANNEL; SUCCINATE SEMIALDEHYDE DEHYDROGENASE; TRANQUILIZER; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; ZINC;

EID: 4243196940     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001518     Document Type: Review
Times cited : (215)

References (260)
  • 3
    • 0034531055 scopus 로고    scopus 로고
    • The economic burden of bipolar disease
    • Woods SW. The economic burden of bipolar disease. J Clin Psychiatry 2000; 61(Supp 13): 38-41.
    • (2000) J Clin Psychiatry , vol.61 , Issue.13 SUPPL. , pp. 38-41
    • Woods, S.W.1
  • 4
    • 0141497925 scopus 로고    scopus 로고
    • Social and economic burden of mood disorders
    • Simon GE. Social and economic burden of mood disorders. Biol Psychiatry 2003; 54: 208-215.
    • (2003) Biol Psychiatry , vol.54 , pp. 208-215
    • Simon, G.E.1
  • 5
    • 0042477758 scopus 로고    scopus 로고
    • Insurance expenditures on bipolar disorder: Clinical and parity implications
    • Peele PB, Xu Y, Kupfer DJ. Insurance expenditures on bipolar disorder: clinical and parity implications. Am J Psychiatry 2003; 160: 1286-1290.
    • (2003) Am J Psychiatry , vol.160 , pp. 1286-1290
    • Peele, P.B.1    Xu, Y.2    Kupfer, D.J.3
  • 8
    • 0141831646 scopus 로고    scopus 로고
    • Mood disorders and medical illness: A major public health problem
    • Evans DL, Charney DS. Mood disorders and medical illness: a major public health problem. Biol Psychiatry 2003; 54: 177-180.
    • (2003) Biol Psychiatry , vol.54 , pp. 177-180
    • Evans, D.L.1    Charney, D.S.2
  • 9
    • 0037799006 scopus 로고    scopus 로고
    • Safety of available agents used to treat bipolar disorder: Focus on weight gain
    • Nemeroff CB. Safety of available agents used to treat bipolar disorder: focus on weight gain. J Clin Psychiatry 2003; 64: 532-539.
    • (2003) J Clin Psychiatry , vol.64 , pp. 532-539
    • Nemeroff, C.B.1
  • 10
    • 0011763375 scopus 로고    scopus 로고
    • Current and emerging treatments for acute mania and long-term prophylaxis for bipolar disorder
    • Davis KL, Charney DS, Coyle JT, Nemeroff CB (eds). Lippincott Williams & Wilkins: Philadelphia
    • Keck Jr PE, Manji HK. Current and emerging treatments for acute mania and long-term prophylaxis for bipolar disorder. In: Davis KL, Charney DS, Coyle JT, Nemeroff CB (eds). Neuropsychopharmacology: The Fifth Generation of Progress. Lippincott Williams & Wilkins: Philadelphia, 2002 pp 1109-1118.
    • (2002) Neuropsychopharmacology: The Fifth Generation of Progress , pp. 1109-1118
    • Keck Jr., P.E.1    Manji, H.K.2
  • 12
    • 0036342208 scopus 로고    scopus 로고
    • Antiepileptic drugs in psychiatry-focus on randomized controlled trial
    • Muzina DJ, El-Sayegh S, Calabrese JR. Antiepileptic drugs in psychiatry-focus on randomized controlled trial. Epilepsy Res 2002; 50: 195-202.
    • (2002) Epilepsy Res , vol.50 , pp. 195-202
    • Muzina, D.J.1    El-Sayegh, S.2    Calabrese, J.R.3
  • 14
    • 4243165658 scopus 로고    scopus 로고
    • Emerging experimental therapeutics for bipolar disorder: Clues from the molecular pathophysiology
    • in press
    • Quiroz J, Singh J, Gould TD, Zarate CA, Manji HK. Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology. Mol Psychiatry, in press.
    • Mol Psychiatry
    • Quiroz, J.1    Singh, J.2    Gould, T.D.3    Zarate, C.A.4    Manji, H.K.5
  • 15
    • 0036705074 scopus 로고    scopus 로고
    • Signaling networks in the pathophysiology and treatment of mood disorders
    • Gould TD, Manji HK. Signaling networks in the pathophysiology and treatment of mood disorders. J Psychosom Res 2002; 53: 687-697.
    • (2002) J Psychosom Res , vol.53 , pp. 687-697
    • Gould, T.D.1    Manji, H.K.2
  • 16
    • 0033014180 scopus 로고    scopus 로고
    • The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3
    • Chen G, Huang LD, Jiang YM, Manji HK. The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3. J Neurochem 1999; 72: 1327-1330.
    • (1999) J Neurochem , vol.72 , pp. 1327-1330
    • Chen, G.1    Huang, L.D.2    Jiang, Y.M.3    Manji, H.K.4
  • 18
    • 4243133277 scopus 로고    scopus 로고
    • The cellular neurobiology of severe mood and anxiety disorders: Implications for the development of novel therapeutics
    • Charney DS (ed). American Psychiatric Press. Inc.: Washington
    • Gould TD, Gray NA, Manji HK. The cellular neurobiology of severe mood and anxiety disorders: implications for the development of novel therapeutics. In: Charney DS (ed). Molecular Neurobiology for the Clinician. American Psychiatric Press. Inc.: Washington, 2003 pp 123-227.
    • (2003) Molecular Neurobiology for the Clinician , pp. 123-227
    • Gould, T.D.1    Gray, N.A.2    Manji, H.K.3
  • 19
    • 0037688084 scopus 로고    scopus 로고
    • Finding the intracellular signaling pathways affected by mood disorder treatments
    • Coyle JT, Duman RS. Finding the intracellular signaling pathways affected by mood disorder treatments. Neuron 2003; 38: 157-160.
    • (2003) Neuron , vol.38 , pp. 157-160
    • Coyle, J.T.1    Duman, R.S.2
  • 21
    • 0033564972 scopus 로고    scopus 로고
    • Comparison of fluorescence, (31)P NMR, and (7)Li NMR spectroscopic methods for investigating Li(+)/Mg(2+) competition for biomolecules
    • Amari L, Layden B, Rong Q, Geraldes CF, Mota de Freitas D. Comparison of fluorescence, (31)P NMR, and (7)Li NMR spectroscopic methods for investigating Li(+)/Mg(2+) competition for biomolecules. Anal Biochem 1999; 272: 1-7.
    • (1999) Anal Biochem , vol.272 , pp. 1-7
    • Amari, L.1    Layden, B.2    Rong, Q.3    Geraldes, C.F.4    Mota De Freitas, D.5
  • 22
    • 0034805180 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
    • Ryves WJ, Harwood AJ. Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem Biophys Res Commun 2001; 280: 720-725.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 720-725
    • Ryves, W.J.1    Harwood, A.J.2
  • 24
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000; 351: 95-105.
    • (2000) Biochem J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 25
    • 0029036695 scopus 로고
    • Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure
    • York JD, Ponder JW, Majerus PW. Definition of a metal-dependent/Li(+)- inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. Proc Natl Acad Sci USA 1995; 92: 5149-5153.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5149-5153
    • York, J.D.1    Ponder, J.W.2    Majerus, P.W.3
  • 26
    • 0033532046 scopus 로고    scopus 로고
    • Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3′-nucleotidase inhibited by inositol 1,4-bisphosphate
    • Spiegelberg BD, Xiong JP, Smith JJ, Gu RF, York JD. Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3′-nucleotidase inhibited by inositol 1,4-bisphosphate. J Biol Chem 1999; 274: 13619-13628.
    • (1999) J Biol Chem , vol.274 , pp. 13619-13628
    • Spiegelberg, B.D.1    Xiong, J.P.2    Smith, J.J.3    Gu, R.F.4    York, J.D.5
  • 27
    • 0020044028 scopus 로고
    • Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose-1,6-diphosphate levels in rat muscles, brain and liver
    • Nordenberg J, Kaplansky M, Beery E, Klein S, Beitner R. Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose-1,6-diphosphate levels in rat muscles, brain and liver. Biochem Pharmacol 1982; 31: 1025-1031.
    • (1982) Biochem Pharmacol , vol.31 , pp. 1025-1031
    • Nordenberg, J.1    Kaplansky, M.2    Beery, E.3    Klein, S.4    Beitner, R.5
  • 28
    • 0021765663 scopus 로고
    • Enzyme-bound intermediates in the conversion of glucose 1-phosphate to glucose 6-phosphate by phosphoglucomutase. Phosphorus NMR studies
    • Rhyu GI, Ray Jr WJ, Markley JL. Enzyme-bound intermediates in the conversion of glucose 1-phosphate to glucose 6-phosphate by phosphoglucomutase. Phosphorus NMR studies. Biochemistry 1984; 23: 252-260.
    • (1984) Biochemistry , vol.23 , pp. 252-260
    • Rhyu, G.I.1    Ray Jr., W.J.2    Markley, J.L.3
  • 29
    • 0017861963 scopus 로고
    • The binding of lithium and of anionic metabolites to phosphoglucomutase
    • Ray Jr WJ, Szymanki ES, Ng L. The binding of lithium and of anionic metabolites to phosphoglucomutase. Biochim Biophys Acta 1978; 522: 434-442.
    • (1978) Biochim Biophys Acta , vol.522 , pp. 434-442
    • Ray Jr., W.J.1    Szymanki, E.S.2    Ng, L.3
  • 31
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein PS, Melton DA. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA 1996; 93: 8455-8459.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 32
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
    • Stambolic V, Ruel L, Woodgett JR. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr Biol 1996; 6: 1664-1668.
    • (1996) Curr Biol , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 33
    • 0036810240 scopus 로고    scopus 로고
    • Lithium and valproic acid: Parallels and contrasts in diverse signaling contexts
    • Gurvich N, Klein PS. Lithium and valproic acid: parallels and contrasts in diverse signaling contexts. Pharmacol Ther 2002; 96: 45-66.
    • (2002) Pharmacol Ther , vol.96 , pp. 45-66
    • Gurvich, N.1    Klein, P.S.2
  • 34
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through beta-catenin
    • Moon RT, Bowerman B, Boutros M, Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science 2002; 296: 1644-1646.
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 35
    • 0035909112 scopus 로고    scopus 로고
    • Judging a protein by more than its name: Gsk-3
    • Woodgett JR. Judging a protein by more than its name: gsk-3. Sci STKE 2001; 2001: RE12.
    • (2001) Sci STKE , vol.2001
    • Woodgett, J.R.1
  • 37
    • 0035808457 scopus 로고    scopus 로고
    • Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/ p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?
    • Leclerc S, Garnier M, Hoessel R, Marko D, Bibb JA, Snyder GL et al. Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/ p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? J Biol Chem 2001; 276: 251-260.
    • (2001) J Biol Chem , vol.276 , pp. 251-260
    • Leclerc, S.1    Garnier, M.2    Hoessel, R.3    Marko, D.4    Bibb, J.A.5    Snyder, G.L.6
  • 38
    • 0035848403 scopus 로고    scopus 로고
    • 3-Anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)
    • Smith DG, Buffet M, Fenwick AE, Haigh D, Ife RJ, Saunders M et al. 3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3). Bioorg Med Chem Lett 2001; 11: 635-639.
    • (2001) Bioorg Med Chem Lett , vol.11 , pp. 635-639
    • Smith, D.G.1    Buffet, M.2    Fenwick, A.E.3    Haigh, D.4    Ife, R.J.5    Saunders, M.6
  • 39
    • 0242664588 scopus 로고    scopus 로고
    • Structural insights and biological effects of glycogen synthase kinase 3 specific inhibitor AR-A014418
    • Bhat RV, Xue Y, Berg S, Hellberg S, Ormo M, Nilsson Y et al. Structural insights and biological effects of glycogen synthase kinase 3 specific inhibitor AR-A014418. J Biol Chem 2003; 278: 45937-45945.
    • (2003) J Biol Chem , vol.278 , pp. 45937-45945
    • Bhat, R.V.1    Xue, Y.2    Berg, S.3    Hellberg, S.4    Ormo, M.5    Nilsson, Y.6
  • 40
    • 0036302960 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle
    • Nikoulina SE, Ciaraldi TP, Mudaliar S, Carter L, Johnson K, Henry RR. Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle. Diabetes 2002; 51: 2190-2198.
    • (2002) Diabetes , vol.51 , pp. 2190-2198
    • Nikoulina, S.E.1    Ciaraldi, T.P.2    Mudaliar, S.3    Carter, L.4    Johnson, K.5    Henry, R.R.6
  • 41
    • 0037075791 scopus 로고    scopus 로고
    • First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease
    • Martinez A, Alonso M, Castro A, Perez C, Moreno FJ. First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease. J Med Chem 2002; 45: 1292-1299.
    • (2002) J Med Chem , vol.45 , pp. 1292-1299
    • Martinez, A.1    Alonso, M.2    Castro, A.3    Perez, C.4    Moreno, F.J.5
  • 42
    • 0038811796 scopus 로고    scopus 로고
    • Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3
    • Plotkin B, Kaidanovich O, Talior I, Eldar-Finkelman H. Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3. J Pharmacol Exp Ther 2003; 305: 974-980.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 974-980
    • Plotkin, B.1    Kaidanovich, O.2    Talior, I.3    Eldar-Finkelman, H.4
  • 43
    • 0026659202 scopus 로고
    • Inositol phosphate biochemistry
    • Majerus PW. Inositol phosphate biochemistry. Annu Rev Biochem 1992; 61: 225-250.
    • (1992) Annu Rev Biochem , vol.61 , pp. 225-250
    • Majerus, P.W.1
  • 44
    • 0024341795 scopus 로고
    • Neural and developmental actions of lithium: A unifying hypothesis
    • Berridge MJ, Downes CP, Hanley MR. Neural and developmental actions of lithium: a unifying hypothesis. Cell 1989; 59: 411-419.
    • (1989) Cell , vol.59 , pp. 411-419
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 45
    • 0030898340 scopus 로고    scopus 로고
    • Inositol monophosphatase inhibitors - Lithium mimetics?
    • Atack JR. Inositol monophosphatase inhibitors - lithium mimetics? Med Res Rev 1997; 17: 215-224.
    • (1997) Med Res Rev , vol.17 , pp. 215-224
    • Atack, J.R.1
  • 46
    • 0027458537 scopus 로고
    • In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330
    • Atack JR, Cook SM, Watt AP, Fletcher SR, Ragan CI. In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330. J Neurochem 1993; 60: 652-658.
    • (1993) J Neurochem , vol.60 , pp. 652-658
    • Atack, J.R.1    Cook, S.M.2    Watt, A.P.3    Fletcher, S.R.4    Ragan, C.I.5
  • 47
    • 0028339390 scopus 로고
    • Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers
    • Atack JR, Prior AM, Fletcher SR, Quirk K, McKernan R, Ragan CI. Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers. J Pharmacol Exp Ther 1994; 270: 70-76.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 70-76
    • Atack, J.R.1    Prior, A.M.2    Fletcher, S.R.3    Quirk, K.4    McKernan, R.5    Ragan, C.I.6
  • 48
    • 1442284539 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3: A target for novel bipolar disolder treatments
    • Gould TD, Zarate CA, Manji HK. Glycogen synthase kinase-3: a target for novel bipolar disolder treatments. J Clin Psychiatry 2004; 65: 10-21.
    • (2004) J Clin Psychiatry , vol.65 , pp. 10-21
    • Gould, T.D.1    Zarate, C.A.2    Manji, H.K.3
  • 50
    • 0016231591 scopus 로고
    • Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes
    • Naccarato WF, Ray RE, Wells WW. Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes. Arch Biochem Biophys 1974; 164: 194-201.
    • (1974) Arch Biochem Biophys , vol.164 , pp. 194-201
    • Naccarato, W.F.1    Ray, R.E.2    Wells, W.W.3
  • 51
    • 0019127799 scopus 로고
    • The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain
    • Hallcher LM, Sherman WR. The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain. J Biol Chem 1980; 255: 10896-10901.
    • (1980) J Biol Chem , vol.255 , pp. 10896-10901
    • Hallcher, L.M.1    Sherman, W.R.2
  • 52
    • 0023706194 scopus 로고
    • The dephosphorylation of inositol 1,4-bisphosphate to inositol in liver and brain involves two distinct Li+-sensitive enzymes and proceeds via inositol 4-phosphate
    • Ragan CI, Watling KJ, Gee NS, Aspley S, Jackson RG, Reid GG et al. The dephosphorylation of inositol 1,4-bisphosphate to inositol in liver and brain involves two distinct Li+-sensitive enzymes and proceeds via inositol 4-phosphate. Biochem J 1988; 249: 143-148.
    • (1988) Biochem J , vol.249 , pp. 143-148
    • Ragan, C.I.1    Watling, K.J.2    Gee, N.S.3    Aspley, S.4    Jackson, R.G.5    Reid, G.G.6
  • 53
    • 0023705726 scopus 로고
    • Properties of inositol polyphosphate 1-phosphatase
    • Inhorn RC, Majerus PW. Properties of inositol polyphosphate 1-phosphatase. J Biol Chem 1988; 263: 14559-14565.
    • (1988) J Biol Chem , vol.263 , pp. 14559-14565
    • Inhorn, R.C.1    Majerus, P.W.2
  • 54
    • 0020465411 scopus 로고
    • Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands
    • Berridge MJ, Downes CP, Hanley MR. Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem J 1982; 206: 587-595.
    • (1982) Biochem J , vol.206 , pp. 587-595
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 55
    • 0025912111 scopus 로고
    • Lithium and the phosphoinositide cycle: An example of uncompetitive inhibition and its pharmacological consequences
    • Nahorski SR, Ragan CI, Challiss RA. Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences. Trends Pharmacol Sci 1991; 12: 297-303.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 297-303
    • Nahorski, S.R.1    Ragan, C.I.2    Challiss, R.A.3
  • 56
    • 0015242494 scopus 로고
    • Reduced brain inositol in lithium-treated rats
    • Allison JH, Stewart MA. Reduced brain inositol in lithium-treated rats. Nat New Biol 1971; 233: 267-268.
    • (1971) Nat New Biol , vol.233 , pp. 267-268
    • Allison, J.H.1    Stewart, M.A.2
  • 57
    • 0008836304 scopus 로고    scopus 로고
    • Lithium, phosphatidylinositol signaling, and bipolar disorder
    • Manji HK, Bowden CL, Belmaker RH (eds). American Psychiatric Press, Inc.: Washington, DC
    • Atack, JR. Lithium, phosphatidylinositol signaling, and bipolar disorder. In: Manji HK, Bowden CL, Belmaker RH (eds). Bipolar Medications: Mechanism of Action. American Psychiatric Press, Inc.: Washington, DC, 2000.
    • (2000) Bipolar Medications: Mechanism of Action
    • Atack, J.R.1
  • 58
    • 0032744013 scopus 로고    scopus 로고
    • Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness
    • Moore GJ, Bebchuk JM, Parrish JK, Faulk MW, Arfken CL, Strahl-Bevacqua J et al. Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness. Am J Psychiatry 1999; 156: 1902-1908.
    • (1999) Am J Psychiatry , vol.156 , pp. 1902-1908
    • Moore, G.J.1    Bebchuk, J.M.2    Parrish, J.K.3    Faulk, M.W.4    Arfken, C.L.5    Strahl-Bevacqua, J.6
  • 60
    • 0026493674 scopus 로고
    • Structure of inositol monophosphatase, the putative target of lithium therapy
    • Bone R, Springer JP, Atack JR. Structure of inositol monophosphatase, the putative target of lithium therapy. Proc Natl Acad Sci USA 1992; 89: 10031-10035.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10031-10035
    • Bone, R.1    Springer, J.P.2    Atack, J.R.3
  • 61
    • 0022622039 scopus 로고
    • Lithium-induced respecification of pattern in Xenopus laevis embryos
    • Kao KR, Masui Y, Elinson RP. Lithium-induced respecification of pattern in Xenopus laevis embryos. Nature 1986; 322: 371-373.
    • (1986) Nature , vol.322 , pp. 371-373
    • Kao, K.R.1    Masui, Y.2    Elinson, R.P.3
  • 62
    • 0028931511 scopus 로고
    • Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
    • He X, Saint-Jeannet JP, Woodgett JR, Varmus HE, Dawid IB. Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 1995; 374: 617-622.
    • (1995) Nature , vol.374 , pp. 617-622
    • He, X.1    Saint-Jeannet, J.P.2    Woodgett, J.R.3    Varmus, H.E.4    Dawid, I.B.5
  • 63
    • 0346688565 scopus 로고    scopus 로고
    • In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3
    • Gould TD, Chen G, Manji HK. In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 2004; 29: 32-38.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 32-38
    • Gould, T.D.1    Chen, G.2    Manji, H.K.3
  • 64
    • 0037087220 scopus 로고    scopus 로고
    • Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
    • Sun X, Sato S, Murayama O, Murayama M, Park JM, Yamaguchi H et al. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci Lett 2002; 321: 61-64.
    • (2002) Neurosci Lett , vol.321 , pp. 61-64
    • Sun, X.1    Sato, S.2    Murayama, O.3    Murayama, M.4    Park, J.M.5    Yamaguchi, H.6
  • 65
    • 0038187674 scopus 로고    scopus 로고
    • GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
    • Phiel CJ, Wilson CA, Lee VM, Klein PS. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 2003; 423: 435-439.
    • (2003) Nature , vol.423 , pp. 435-439
    • Phiel, C.J.1    Wilson, C.A.2    Lee, V.M.3    Klein, P.S.4
  • 66
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • Frame S, Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem J 2001; 359: 1-16.
    • (2001) Biochem J , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 67
    • 0036788036 scopus 로고    scopus 로고
    • The wnt signaling pathway in bipolar disorder
    • Gould TD, Manji HK. The wnt signaling pathway in bipolar disorder. Neuroscientist 2002; 8: 497-511.
    • (2002) Neuroscientist , vol.8 , pp. 497-511
    • Gould, T.D.1    Manji, H.K.2
  • 69
    • 0036214603 scopus 로고    scopus 로고
    • Mood stabilizers, glycogen synthase kinase-3beta and cell survival
    • Jope RS, Bijur GN. Mood stabilizers, glycogen synthase kinase-3beta and cell survival. Mol Psychiatry 2002; 7(Suppl 1): S35-S45.
    • (2002) Mol Psychiatry , vol.7 , Issue.1 SUPPL.
    • Jope, R.S.1    Bijur, G.N.2
  • 70
    • 0032827466 scopus 로고    scopus 로고
    • Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?
    • Manji HK, Moore GJ, Chen G. Lithium at 50: have the neuroprotective effects of this unique cation been overlooked? Biol Psychiatry 1999; 46: 929-940.
    • (1999) Biol Psychiatry , vol.46 , pp. 929-940
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 72
    • 1842420631 scopus 로고    scopus 로고
    • Rapid antidepressive-like activity of specific glycogen synthase kinase-3inhibitor and its effect on beta-catenin in mouse hippocampus
    • Kaidanovich-Beilin O, Milman A, Weizman A, Pick CG, Eldar-Finkelman H. Rapid antidepressive-like activity of specific glycogen synthase kinase-3inhibitor and its effect on beta-catenin in mouse hippocampus. Biol Psychiatry 2004; 55: 781-784.
    • (2004) Biol Psychiatry , vol.55 , pp. 781-784
    • Kaidanovich-Beilin, O.1    Milman, A.2    Weizman, A.3    Pick, C.G.4    Eldar-Finkelman, H.5
  • 76
    • 0036398986 scopus 로고    scopus 로고
    • The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes
    • Kaidanovich O, Eldar-Finkelman H. The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes. Expert Opin Ther Targets 2002; 6: 555-561.
    • (2002) Expert Opin Ther Targets , vol.6 , pp. 555-561
    • Kaidanovich, O.1    Eldar-Finkelman, H.2
  • 77
    • 0036769733 scopus 로고    scopus 로고
    • GSK3beta signalling: Casting a wide net in Alzheimer's disease
    • Bhat RV, Budd SL. GSK3beta signalling: casting a wide net in Alzheimer's disease. Neurosignals 2002; 11: 251-261.
    • (2002) Neurosignals , vol.11 , pp. 251-261
    • Bhat, R.V.1    Budd, S.L.2
  • 78
    • 0036276050 scopus 로고    scopus 로고
    • Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
    • Alvarez G, Munoz-Montano JR, Satrustegui J, Avila J, Bogonez E, Diaz-Nido J. Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord 2002; 4: 153-165.
    • (2002) Bipolar Disord , vol.4 , pp. 153-165
    • Alvarez, G.1    Munoz-Montano, J.R.2    Satrustegui, J.3    Avila, J.4    Bogonez, E.5    Diaz-Nido, J.6
  • 79
    • 0037040856 scopus 로고    scopus 로고
    • Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase - Dependent pathway is cardioprotective
    • Tong H, Imahashi K, Steenbergen C, Murphy E. Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3- kinase - dependent pathway is cardioprotective. Circ Res 2002; 90: 377-379.
    • (2002) Circ Res , vol.90 , pp. 377-379
    • Tong, H.1    Imahashi, K.2    Steenbergen, C.3    Murphy, E.4
  • 80
    • 0037609376 scopus 로고    scopus 로고
    • Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model
    • Ren M, Senatorov W, Chen RW, Chuang DM. Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model. Proc Natl Acad Sci USA 2003; 100: 6210-6215.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 6210-6215
    • Ren, M.1    Senatorov, W.2    Chen, R.W.3    Chuang, D.M.4
  • 81
    • 0034718421 scopus 로고    scopus 로고
    • Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration
    • Bhat RV, Shanley J, Correll MP, Fieles WE, Keith RA, Scott CW et al. Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration. Proc Natl Acad Sci USA 2000; 97: 11074-11079.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 11074-11079
    • Bhat, R.V.1    Shanley, J.2    Correll, M.P.3    Fieles, W.E.4    Keith, R.A.5    Scott, C.W.6
  • 82
    • 0036302005 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3beta by bivalent zinc ions: Insight into the insulin-mimetic action of zinc
    • Ilouz R, Kaidanovich O, Gurwitz D, Eldar-Finkelman H. Inhibition of glycogen synthase kinase-3beta by bivalent zinc ions: insight into the insulin-mimetic action of zinc. Biochem Biophys Res Commun 2002; 295: 102-106.
    • (2002) Biochem Biophys Res Commun , vol.295 , pp. 102-106
    • Ilouz, R.1    Kaidanovich, O.2    Gurwitz, D.3    Eldar-Finkelman, H.4
  • 83
    • 0033776383 scopus 로고    scopus 로고
    • Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
    • Coghlan MP, Culbert AA, Cross DA, Corcoran SL, Yates JW, Pearce NJ et al. Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem Biol 2000; 7: 793-803.
    • (2000) Chem Biol , vol.7 , pp. 793-803
    • Coghlan, M.P.1    Culbert, A.A.2    Cross, D.A.3    Corcoran, S.L.4    Yates, J.W.5    Pearce, N.J.6
  • 84
    • 0035087123 scopus 로고    scopus 로고
    • Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death
    • Cross DA, Culbert AA, Chalmers KA, Facci L, Skaper SD, Reith AD. Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death. J Neurochem 2001; 77: 94-102.
    • (2001) J Neurochem , vol.77 , pp. 94-102
    • Cross, D.A.1    Culbert, A.A.2    Chalmers, K.A.3    Facci, L.4    Skaper, S.D.5    Reith, A.D.6
  • 85
    • 0032705583 scopus 로고    scopus 로고
    • The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220) are potent inhibitors of glycogen synthase kinase-3 activity
    • Hers I, Tavare JM, Denton RM. The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220) are potent inhibitors of glycogen synthase kinase-3 activity. FEBS Lett 1999; 460: 433-436.
    • (1999) FEBS Lett , vol.460 , pp. 433-436
    • Hers, I.1    Tavare, J.M.2    Denton, R.M.3
  • 86
    • 0034010742 scopus 로고    scopus 로고
    • Inhibition of cyclin-dependent kinases GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent
    • Meijer L, Thunnissen AM, White AW, Garnier M, Nikolic M, Tsai LH et al. Inhibition of cyclin-dependent kinases GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent. Chem Biol 2000; 7: 51-63.
    • (2000) Chem Biol , vol.7 , pp. 51-63
    • Meijer, L.1    Thunnissen, A.M.2    White, A.W.3    Garnier, M.4    Nikolic, M.5    Tsai, L.H.6
  • 87
    • 0033798031 scopus 로고    scopus 로고
    • Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25
    • Leost M, Schultz C, Link A, Wu YZ, Biernat J, Mandelkow EM et al. Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25. Eur J Biochem 2000; 267: 5983-5994.
    • (2000) Eur J Biochem , vol.267 , pp. 5983-5994
    • Leost, M.1    Schultz, C.2    Link, A.3    Wu, Y.Z.4    Biernat, J.5    Mandelkow, E.M.6
  • 88
    • 0036799220 scopus 로고    scopus 로고
    • Inhibitors of glycogen synthase kinase-3: Future therapy for unmet medical needs
    • Dorronsoro I, Castro A, Martinez A. Inhibitors of glycogen synthase kinase-3: future therapy for unmet medical needs. Expert Opin Ther Patents 2002; 12: 1527-1536.
    • (2002) Expert Opin Ther Patents , vol.12 , pp. 1527-1536
    • Dorronsoro, I.1    Castro, A.2    Martinez, A.3
  • 89
    • 0036273020 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation
    • Martinez A, Castro A, Dorronsoro I, Alonso M. Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation. Med Res Rev 2002; 22: 373-384.
    • (2002) Med Res Rev , vol.22 , pp. 373-384
    • Martinez, A.1    Castro, A.2    Dorronsoro, I.3    Alonso, M.4
  • 90
    • 1642503034 scopus 로고    scopus 로고
    • Effect of zinc supplementation on antidepressant therapy in unipolar depression: A preliminary placebo-controlled study
    • Nowak G, Siwek M, Dudek D, Zieba A, Pilc A. Effect of zinc supplementation on antidepressant therapy in unipolar depression: a preliminary placebo-controlled study. Pol J Pharmacol 2003; 55: 1143-1147.
    • (2003) Pol J Pharmacol , vol.55 , pp. 1143-1147
    • Nowak, G.1    Siwek, M.2    Dudek, D.3    Zieba, A.4    Pilc, A.5
  • 91
    • 0035872392 scopus 로고    scopus 로고
    • Antidepressant-like properties of zinc in rodent forced swim test
    • Kroczka B, Branski P, Palucha A, Pilc A, Nowak G. Antidepressant-like properties of zinc in rodent forced swim test. Brain Res Bull 2001; 55: 297-300.
    • (2001) Brain Res Bull , vol.55 , pp. 297-300
    • Kroczka, B.1    Branski, P.2    Palucha, A.3    Pilc, A.4    Nowak, G.5
  • 92
    • 0037707701 scopus 로고    scopus 로고
    • Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats
    • Nowak G, Szewczyk B, Wieronska JM, Branski P, Palucha A, Pilc A et al. Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats. Brain Res Bull 2003; 61: 159-164.
    • (2003) Brain Res Bull , vol.61 , pp. 159-164
    • Nowak, G.1    Szewczyk, B.2    Wieronska, J.M.3    Branski, P.4    Palucha, A.5    Pilc, A.6
  • 93
    • 0033665173 scopus 로고    scopus 로고
    • Zinc exhibits an antidepressant-like effect in the forced swimming test in mice
    • Kroczka B, Zieba A, Dudek D, Pilc A, Nowak G. Zinc exhibits an antidepressant-like effect in the forced swimming test in mice. Pol J Pharmacol 2000; 52: 403-406.
    • (2000) Pol J Pharmacol , vol.52 , pp. 403-406
    • Kroczka, B.1    Zieba, A.2    Dudek, D.3    Pilc, A.4    Nowak, G.5
  • 95
    • 0018972024 scopus 로고
    • Purification and properties of liver fructose 1,6-bisphosphatase from C57BL/KsJ normal and diabetic mice
    • Marcus F, Hosey MM. Purification and properties of liver fructose 1,6-bisphosphatase from C57BL/KsJ normal and diabetic mice. J Biol Chem 1980; 255: 2481-2486.
    • (1980) J Biol Chem , vol.255 , pp. 2481-2486
    • Marcus, F.1    Hosey, M.M.2
  • 96
    • 0017179353 scopus 로고
    • Size-dependent allosteric effects of monovalent cations on rabbit liver fructose-1,6-bisphosphatase
    • Nakashima K, Tuboi S. Size-dependent allosteric effects of monovalent cations on rabbit liver fructose-1,6-bisphosphatase. J Biol Chem 1976; 251: 4315-4321.
    • (1976) J Biol Chem , vol.251 , pp. 4315-4321
    • Nakashima, K.1    Tuboi, S.2
  • 97
    • 0029088924 scopus 로고
    • Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase
    • Villeret V, Huang S, Fromm HJ, Lipscomb WN. Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6- bisphosphatase. Proc Natl Acad Sci USA 1995; 92: 8916-8920.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8916-8920
    • Villeret, V.1    Huang, S.2    Fromm, H.J.3    Lipscomb, W.N.4
  • 98
    • 0029980322 scopus 로고    scopus 로고
    • Kinetics and mechanisms of activation and inhibition of porcine liver fructose-1,6-bisphosphatase by monovalent cations
    • Zhang R, Villeret V, Lipscomb WN, Fromm HJ. Kinetics and mechanisms of activation and inhibition of porcine liver fructose-1,6-bisphosphatase by monovalent cations. Biochemistry 1996; 35: 3038-3043.
    • (1996) Biochemistry , vol.35 , pp. 3038-3043
    • Zhang, R.1    Villeret, V.2    Lipscomb, W.N.3    Fromm, H.J.4
  • 99
    • 0038778445 scopus 로고    scopus 로고
    • 3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: An allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site
    • Wright SW, Carlo AA, Danley DE, Hageman DL, Karam GA, Mansour MN et al. 3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site. Bioorg Med Chem Lett 2003; 13: 2055-2058.
    • (2003) Bioorg Med Chem Lett , vol.13 , pp. 2055-2058
    • Wright, S.W.1    Carlo, A.A.2    Danley, D.E.3    Hageman, D.L.4    Karam, G.A.5    Mansour, M.N.6
  • 100
    • 0039772523 scopus 로고    scopus 로고
    • A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3′-phosphoadenosine 5′-phosphate phosphatase and inositol-polyphosphate 1-phosphatase
    • Lopez-Coronado JM, Belles JM, Lesage F, Serrano R, Rodriguez PL. A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3′-phosphoadenosine 5′-phosphate phosphatase and inositol-polyphosphate 1-phosphatase. J Biol Chem 1999; 274: 16034-16039.
    • (1999) J Biol Chem , vol.274 , pp. 16034-16039
    • Lopez-Coronado, J.M.1    Belles, J.M.2    Lesage, F.3    Serrano, R.4    Rodriguez, P.L.5
  • 102
    • 0036305698 scopus 로고    scopus 로고
    • Crystal structure of an enzyme displaying both inositol-polyphosphate-1- phosphatase and 3′-phosphoadenosine-5′-phosphate phosphatase activities: A novel target of lithium therapy
    • Patel S, Yenush L, Rodriguez PL, Serrano R, Blundell TL. Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3′-phosphoadenosine-5′-phosphate phosphatase activities: a novel target of lithium therapy. J Mol Biol 2002; 315: 677-685.
    • (2002) J Mol Biol , vol.315 , pp. 677-685
    • Patel, S.1    Yenush, L.2    Rodriguez, P.L.3    Serrano, R.4    Blundell, T.L.5
  • 103
    • 0041630998 scopus 로고    scopus 로고
    • Possible role of 3′(2′)-phosphoadenosine-5′-phosphate phosphatase in the etiology and therapy of bipolar disorder
    • Agam G, Shaltiel G. Possible role of 3′(2′)-phosphoadenosine- 5′-phosphate phosphatase in the etiology and therapy of bipolar disorder. Prog Neuro-psychopharm Biol Psych 2003; 27: 723-727.
    • (2003) Prog Neuro-psychopharm Biol Psych , vol.27 , pp. 723-727
    • Agam, G.1    Shaltiel, G.2
  • 104
    • 0034257051 scopus 로고    scopus 로고
    • Mechanisms of action of valproate: A commentary
    • Johannessen CU. Mechanisms of action of valproate: a commentary. Neurochem Int 2000; 37: 103-110.
    • (2000) Neurochem Int , vol.37 , pp. 103-110
    • Johannessen, C.U.1
  • 106
    • 18244383806 scopus 로고    scopus 로고
    • Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
    • Gottlicher M, Minucci S, Zhu P, Kramer OH, Schimpf A, Giavara S et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J 2001; 20: 6969-6978.
    • (2001) EMBO J , vol.20 , pp. 6969-6978
    • Gottlicher, M.1    Minucci, S.2    Zhu, P.3    Kramer, O.H.4    Schimpf, A.5    Giavara, S.6
  • 107
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 2001; 276: 36734-36741.
    • (2001) J Biol Chem , vol.276 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 109
    • 0029057901 scopus 로고
    • Antiepileptic drug mechanisms of action
    • Macdonald RL, Kelly KM. Antiepileptic drug mechanisms of action. Epilepsia 1995; 36, (Suppl 2) S2-S12.
    • (1995) Epilepsia , vol.36 , Issue.2 SUPPL.
    • Macdonald, R.L.1    Kelly, K.M.2
  • 110
    • 0018774833 scopus 로고
    • Di-n-propylacetate and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase
    • van der Laan JW, de Boer T, Bruinvels J. Di-n-propylacetate and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase. J Neurochem 1979; 32: 1769-1780.
    • (1979) J Neurochem , vol.32 , pp. 1769-1780
    • Van Der Laan, J.W.1    De Boer, T.2    Bruinvels, J.3
  • 111
    • 0017087116 scopus 로고
    • Proceedings: Gamma-aminobutyric acid metabolism and the anticonvulsant action of ethanolamine-o-sulphate and di-n-propylacetate
    • Anlezark GM, Horton RW, Meldrum BS, Sawaya MC, Stephenson JD. Proceedings: gamma-aminobutyric acid metabolism and the anticonvulsant action of ethanolamine-o-sulphate and di-n-propylacetate. Br J Pharmacol 1976; 56: 383P-384P.
    • (1976) Br J Pharmacol , vol.56
    • Anlezark, G.M.1    Horton, R.W.2    Meldrum, B.S.3    Sawaya, M.C.4    Stephenson, J.D.5
  • 112
    • 0016730142 scopus 로고
    • Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA
    • Sawaya MC, Horton RW, Meldrum BS. Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA. Epilepsia 1975; 16: 649-655.
    • (1975) Epilepsia , vol.16 , pp. 649-655
    • Sawaya, M.C.1    Horton, R.W.2    Meldrum, B.S.3
  • 113
    • 0018084690 scopus 로고
    • Effects of the anticonvulsant sodium valproate on gamma-aminobutyrate and aldehyde metabolism in ox brain
    • Whittle SR, Turner AJ. Effects of the anticonvulsant sodium valproate on gamma-aminobutyrate and aldehyde metabolism in ox brain. J Neurochem 1978; 31: 1453-1459.
    • (1978) J Neurochem , vol.31 , pp. 1453-1459
    • Whittle, S.R.1    Turner, A.J.2
  • 114
    • 0014739411 scopus 로고
    • The operation of the gamma-aminobutyrate bypath of the tricarboxylic acid cycle in brain tissue in vitro
    • Balazs R, Machiyama Y, Hammond BJ, Julian T, Richter D. The operation of the gamma-aminobutyrate bypath of the tricarboxylic acid cycle in brain tissue in vitro. Biochem J 1970; 116: 445-461.
    • (1970) Biochem J , vol.116 , pp. 445-461
    • Balazs, R.1    Machiyama, Y.2    Hammond, B.J.3    Julian, T.4    Richter, D.5
  • 116
    • 0029996597 scopus 로고    scopus 로고
    • Effect of valproate on cerebral metabolism and blood flow: An 18F-2-deoxyglucose and 15O water positron emission tomography study
    • Gaillard WD, Zeffiro T, Fazilat S, DeCarli C, Theodore WH. Effect of valproate on cerebral metabolism and blood flow: an 18F-2-deoxyglucose and 15O water positron emission tomography study. Epilepsia 1996; 37: 515-521.
    • (1996) Epilepsia , vol.37 , pp. 515-521
    • Gaillard, W.D.1    Zeffiro, T.2    Fazilat, S.3    DeCarli, C.4    Theodore, W.H.5
  • 117
    • 0014532570 scopus 로고
    • Effects of DI-n-propylacetate, and anticonvulsive compound, on GABA metabolism
    • Godin Y, Heiner L, Mark J, Mandel P. Effects of DI-n-propylacetate, and anticonvulsive compound, on GABA metabolism. J Neurochem 1969; 16: 869-873.
    • (1969) J Neurochem , vol.16 , pp. 869-873
    • Godin, Y.1    Heiner, L.2    Mark, J.3    Mandel, P.4
  • 118
    • 0027480424 scopus 로고
    • Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain
    • Loscher W. Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain. Neurochem Res 1993; 18: 485-502.
    • (1993) Neurochem Res , vol.18 , pp. 485-502
    • Loscher, W.1
  • 119
    • 0022469420 scopus 로고
    • Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes
    • Larsson OM, Gram L, Schousboe I, Schousboe A. Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes. Neuropharmacology 1986; 25: 617-625.
    • (1986) Neuropharmacology , vol.25 , pp. 617-625
    • Larsson, O.M.1    Gram, L.2    Schousboe, I.3    Schousboe, A.4
  • 120
    • 0037237645 scopus 로고    scopus 로고
    • The emerging differential roles of GABAergic and antiglutamatergic agents in bipolar disorders
    • Ketter TA, Wang PW. The emerging differential roles of GABAergic and antiglutamatergic agents in bipolar disorders. J Clin Psychiatry 2003; 64(Suppl 3): 15-20.
    • (2003) J Clin Psychiatry , vol.64 , Issue.3 SUPPL. , pp. 15-20
    • Ketter, T.A.1    Wang, P.W.2
  • 121
    • 0242725534 scopus 로고    scopus 로고
    • Valproate and GABAergic system effects
    • Winterer G. Valproate and GABAergic system effects. Neuropsychopharmacology 2003; 28: 2050-2051.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 2050-2051
    • Winterer, G.1
  • 122
    • 0037168650 scopus 로고    scopus 로고
    • An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability
    • Tremolizzo L, Carboni G, Ruzicka WB, Mitchell CP, Sugaya I, Tueting P et al. An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proc Natl Acad Sci USA 2002; 99: 17095-17100.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 17095-17100
    • Tremolizzo, L.1    Carboni, G.2    Ruzicka, W.B.3    Mitchell, C.P.4    Sugaya, I.5    Tueting, P.6
  • 123
    • 0038380334 scopus 로고    scopus 로고
    • Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus
    • Yildirim E, Zhang Z, Uz T, Chen C, Manev R, Manev H. Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus. Neurosci Lett 2003; 345: 141-143.
    • (2003) Neurosci Lett , vol.345 , pp. 141-143
    • Yildirim, E.1    Zhang, Z.2    Uz, T.3    Chen, C.4    Manev, R.5    Manev, H.6
  • 124
    • 0842325787 scopus 로고    scopus 로고
    • Histone deacetylase is a target of valproic acid-mediated cellular differentiation
    • Gurvich N, Tsygankova OM, Meinkoth JL, Klein PS. Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Res 2004; 64: 1079-1086.
    • (2004) Cancer Res , vol.64 , pp. 1079-1086
    • Gurvich, N.1    Tsygankova, O.M.2    Meinkoth, J.L.3    Klein, P.S.4
  • 126
    • 0037452775 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
    • Hockly E, Richon VM, Woodman B, Smith DL, Zhou X, Rosa E et al. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease. Proc Natl Acad Sci USA 2003; 100: 2041-2046.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2041-2046
    • Hockly, E.1    Richon, V.M.2    Woodman, B.3    Smith, D.L.4    Zhou, X.5    Rosa, E.6
  • 127
    • 0142157600 scopus 로고    scopus 로고
    • Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice
    • Ferrante RJ, Kubilus JK, Lee J, Ryu H, Beesen A, Zucker B et al. Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. J Neurosci 2003; 23: 9418-9427.
    • (2003) J Neurosci , vol.23 , pp. 9418-9427
    • Ferrante, R.J.1    Kubilus, J.K.2    Lee, J.3    Ryu, H.4    Beesen, A.5    Zucker, B.6
  • 128
    • 0021048081 scopus 로고
    • Multiple actions of phenytoin on mouse spinal cord neurons in cell culture
    • McLean MJ, Macdonald RL. Multiple actions of phenytoin on mouse spinal cord neurons in cell culture. J Pharmacol Exp Ther 1983; 227: 779-789.
    • (1983) J Pharmacol Exp Ther , vol.227 , pp. 779-789
    • McLean, M.J.1    Macdonald, R.L.2
  • 129
    • 0024372376 scopus 로고
    • Phenytoin and carbamazepine: Potential-and frequency-dependent block of Na currents in mammalian myelinated nerve fibers
    • Schwarz JR, Grigat G. Phenytoin and carbamazepine: potential-and frequency-dependent block of Na currents in mammalian myelinated nerve fibers. Epilepsia 1989; 30: 286-294.
    • (1989) Epilepsia , vol.30 , pp. 286-294
    • Schwarz, J.R.1    Grigat, G.2
  • 130
    • 0020580701 scopus 로고
    • Modulated anticonvulsant block of sodium channels in nerve and muscle
    • Courtney KR, Etter EF. Modulated anticonvulsant block of sodium channels in nerve and muscle. Eur J Pharmacol 1983; 88: 1-9.
    • (1983) Eur J Pharmacol , vol.88 , pp. 1-9
    • Courtney, K.R.1    Etter, E.F.2
  • 131
    • 0037385145 scopus 로고    scopus 로고
    • A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder
    • Bowden CL, Calabrese JR, Sachs G, Yatham LN, Asghar SA, Hompland M et al. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch Gen Psychiatry 2003; 60: 392-400.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 392-400
    • Bowden, C.L.1    Calabrese, J.R.2    Sachs, G.3    Yatham, L.N.4    Asghar, S.A.5    Hompland, M.6
  • 132
    • 0033004838 scopus 로고    scopus 로고
    • A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression
    • Lamictal 602 Study Group
    • Calabrese JR, Bowden CL, Sachs GS, Ascher JA, Monaghan E, Rudd GD. A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. J Clin Psychiatry 1999; 60: 79-88.
    • (1999) J Clin Psychiatry , vol.60 , pp. 79-88
    • Calabrese, J.R.1    Bowden, C.L.2    Sachs, G.S.3    Ascher, J.A.4    Monaghan, E.5    Rudd, G.D.6
  • 134
    • 0347286967 scopus 로고    scopus 로고
    • Prophylactic effect of phenytoin in bipolar disorder: A controlled study
    • Mishory A, Winokur M, Bersudsky Y. Prophylactic effect of phenytoin in bipolar disorder: a controlled study. Bipolar Disord 2003; 5: 464-467.
    • (2003) Bipolar Disord , vol.5 , pp. 464-467
    • Mishory, A.1    Winokur, M.2    Bersudsky, Y.3
  • 135
    • 0011704679 scopus 로고    scopus 로고
    • Carbamazepine and adenosine receptors
    • Manji HK, Bowden CL, Belmaker RH (eds). American Psychiatric Press: Washington, DC
    • Van Calker D, Biber K, Walden J, Gebicke P, Berger M. Carbamazepine and adenosine receptors. In: Manji HK, Bowden CL, Belmaker RH (eds). Bipolar Medications: Mechanisms of Action. American Psychiatric Press: Washington, DC, 2000 pp 331-345.
    • (2000) Bipolar Medications: Mechanisms of Action , pp. 331-345
    • Van Calker, D.1    Biber, K.2    Walden, J.3    Gebicke, P.4    Berger, M.5
  • 136
    • 0017653593 scopus 로고
    • Cyclic AMP accumulation in cerebral cortical slices: Effect of carbamazepine, phenobarbital, and phenytoin
    • Lewin E, Bleck V. Cyclic AMP accumulation in cerebral cortical slices: effect of carbamazepine, phenobarbital, and phenytoin. Epilepsia 1977; 18: 237-242.
    • (1977) Epilepsia , vol.18 , pp. 237-242
    • Lewin, E.1    Bleck, V.2
  • 137
    • 0021037510 scopus 로고
    • Interactions of the anticonvulsant carbamazepine with adenosine receptors 2. Pharmacological studies
    • Skerritt JH, Johnston GA, Chow SC. Interactions of the anticonvulsant carbamazepine with adenosine receptors 2. Pharmacological studies. Epilepsia 1983; 24: 643-650.
    • (1983) Epilepsia , vol.24 , pp. 643-650
    • Skerritt, J.H.1    Johnston, G.A.2    Chow, S.C.3
  • 138
  • 139
    • 0019943622 scopus 로고
    • A purinergic component in the anticonvulsant action of carbamazepine?
    • Skeritt JH, Davies LP, Johnston GA. A purinergic component in the anticonvulsant action of carbamazepine? Eur J Pharmacol 1982; 82: 195-197.
    • (1982) Eur J Pharmacol , vol.82 , pp. 195-197
    • Skeritt, J.H.1    Davies, L.P.2    Johnston, G.A.3
  • 140
    • 0021171226 scopus 로고
    • Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system
    • Weir RL, Padgett W, Daly JW, Anderson SM. Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system. Epilepsia 1984; 25: 492-498.
    • (1984) Epilepsia , vol.25 , pp. 492-498
    • Weir, R.L.1    Padgett, W.2    Daly, J.W.3    Anderson, S.M.4
  • 141
    • 0024997905 scopus 로고
    • Prospective role for adenosine and adenosinergic systems in psychiatric disorders
    • Durcan MJ, Morgan PF. Prospective role for adenosine and adenosinergic systems in psychiatric disorders. Psychol Med 1990; 20: 475-486.
    • (1990) Psychol Med , vol.20 , pp. 475-486
    • Durcan, M.J.1    Morgan, P.F.2
  • 142
    • 0025756451 scopus 로고
    • Carbamazepine distinguishes between adenosine receptors that mediate different second messenger responses
    • Van Calker D, Steber R, Klotz KN, Greil W. Carbamazepine distinguishes between adenosine receptors that mediate different second messenger responses. Eur J Pharmacol 1991; 206: 285-290.
    • (1991) Eur J Pharmacol , vol.206 , pp. 285-290
    • Van Calker, D.1    Steber, R.2    Klotz, K.N.3    Greil, W.4
  • 144
    • 0023201376 scopus 로고
    • Persistent upregulation of brain adenosine receptors in response to chronic carbamazepine treatment
    • Marangos PJ, Montgomery P, Weiss SR, Patel J, Post RM. Persistent upregulation of brain adenosine receptors in response to chronic carbamazepine treatment. Clin Neuropharmacol 1987; 10: 443-448.
    • (1987) Clin Neuropharmacol , vol.10 , pp. 443-448
    • Marangos, P.J.1    Montgomery, P.2    Weiss, S.R.3    Patel, J.4    Post, R.M.5
  • 145
    • 0030272949 scopus 로고    scopus 로고
    • Carbamazepine inhibits the potentiation by adenosine analogues of agonist induced inositolphosphate formation in hippocampal astrocyte cultures
    • Biber K, Walden J, Gebicke-Harter P, Berger M, van Calker D. Carbamazepine inhibits the potentiation by adenosine analogues of agonist induced inositolphosphate formation in hippocampal astrocyte cultures. Biol Psychiatry 1996; 40: 563-567.
    • (1996) Biol Psychiatry , vol.40 , pp. 563-567
    • Biber, K.1    Walden, J.2    Gebicke-Harter, P.3    Berger, M.4    Van Calker, D.5
  • 146
    • 0030777011 scopus 로고    scopus 로고
    • Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists
    • Maemoto T, Finlayson K, Olverman HJ, Akahane A, Horton RW, Butcher SP. Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists. Br J Pharmacol 1997; 122: 1202-1208.
    • (1997) Br J Pharmacol , vol.122 , pp. 1202-1208
    • Maemoto, T.1    Finlayson, K.2    Olverman, H.J.3    Akahane, A.4    Horton, R.W.5    Butcher, S.P.6
  • 147
    • 0018344034 scopus 로고
    • Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum
    • Palmer GC. Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum. Exp Neurol 1979; 63: 322-335.
    • (1979) Exp Neurol , vol.63 , pp. 322-335
    • Palmer, G.C.1
  • 148
    • 0018409148 scopus 로고
    • Anticonvulsant drug actions on in vitro and in vivo levels of cyclic AMP in the mouse brain
    • Palmer GC, Jones DJ, Medina MA, Stavinoha WB. Anticonvulsant drug actions on in vitro and in vivo levels of cyclic AMP in the mouse brain. Epilepsia 1979; 20: 95-104.
    • (1979) Epilepsia , vol.20 , pp. 95-104
    • Palmer, G.C.1    Jones, D.J.2    Medina, M.A.3    Stavinoha, W.B.4
  • 149
    • 0018357697 scopus 로고
    • Inhibitory effects of anticonvulsant drugs on cyclic nucleotide accumulation in brain
    • Ferrendelli JA, Kinscherf DA. Inhibitory effects of anticonvulsant drugs on cyclic nucleotide accumulation in brain. Ann Neurol 1979; 5: 533-538.
    • (1979) Ann Neurol , vol.5 , pp. 533-538
    • Ferrendelli, J.A.1    Kinscherf, D.A.2
  • 150
    • 0025267418 scopus 로고
    • Chronic carbamazepine down-regulates adenosine A2 receptors: Studies with the putative selective adenosine antagonists PD115,199 and PD116,948
    • Elphick M, Taghavi Z, Powell T, Godfrey PP. Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948. Psychopharmacology 1990; 100: 522-529.
    • (1990) Psychopharmacology , vol.100 , pp. 522-529
    • Elphick, M.1    Taghavi, Z.2    Powell, T.3    Godfrey, P.P.4
  • 152
    • 0026065035 scopus 로고
    • Differential effect of lithium on fos protooncogene expression mediated by receptor and postreceptor activators of protein kinase C and cyclic adenosine monophosphate: Model for its antimanic action
    • Divish MM, Sheftel G, Boyle A, Kalasapudi VD, Papolos DF, Lachman HM. Differential effect of lithium on fos protooncogene expression mediated by receptor and postreceptor activators of protein kinase C and cyclic adenosine monophosphate: model for its antimanic action. J Neurosci Res 1991; 28: 40-48.
    • (1991) J Neurosci Res , vol.28 , pp. 40-48
    • Divish, M.M.1    Sheftel, G.2    Boyle, A.3    Kalasapudi, V.D.4    Papolos, D.F.5    Lachman, H.M.6
  • 153
    • 0036127241 scopus 로고    scopus 로고
    • Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024
    • Ambrosio AF, Soares-Da-Silva P, Carvalho CM, Carvalho AP. Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024. Neurochem Res 2002; 27: 121-130.
    • (2002) Neurochem Res , vol.27 , pp. 121-130
    • Ambrosio, A.F.1    Soares-Da-Silva, P.2    Carvalho, C.M.3    Carvalho, A.P.4
  • 154
    • 0026683504 scopus 로고
    • Dibutyryl cyclic AMP has epileptogenic potential in the hippocampus of freely behaving rats: A combined EEG-intracerebral microdialysis study
    • Ludvig N, Mishra PK, Jobe PC. Dibutyryl cyclic AMP has epileptogenic potential in the hippocampus of freely behaving rats: a combined EEG-intracerebral microdialysis study. Neurosci Lett 1992; 141: 187-191.
    • (1992) Neurosci Lett , vol.141 , pp. 187-191
    • Ludvig, N.1    Mishra, P.K.2    Jobe, P.C.3
  • 155
    • 0036214671 scopus 로고    scopus 로고
    • Synaptic plasticity and mood disorders
    • Duman RS. Synaptic plasticity and mood disorders. Mol Psychiatry 2002; 7(Suppl 1): S29-S34.
    • (2002) Mol Psychiatry , vol.7 , Issue.1 SUPPL.
    • Duman, R.S.1
  • 156
    • 0035295487 scopus 로고    scopus 로고
    • Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics
    • Manji HK, Duman RS. Impairments of neuroplasticity and cellular resilience in severe mood disorders: implications for the development of novel therapeutics. Psychopharmacol Bull 2001; 35: 5-49.
    • (2001) Psychopharmacol Bull , vol.35 , pp. 5-49
    • Manji, H.K.1    Duman, R.S.2
  • 157
    • 0043240266 scopus 로고    scopus 로고
    • The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
    • Einat H, Yuan P, Gould TD, Li J, Du J, Zhang L et al. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J Neurosci 2003; 23: 7311-7316.
    • (2003) J Neurosci , vol.23 , pp. 7311-7316
    • Einat, H.1    Yuan, P.2    Gould, T.D.3    Li, J.4    Du, J.5    Zhang, L.6
  • 158
    • 0034795827 scopus 로고    scopus 로고
    • Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain
    • Fukumoto T, Morinobu S, Okamoto Y, Kagaya A, Yamawaki S. Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology (Berl) 2001; 158: 100-106.
    • (2001) Psychopharmacology (Berl) , vol.158 , pp. 100-106
    • Fukumoto, T.1    Morinobu, S.2    Okamoto, Y.3    Kagaya, A.4    Yamawaki, S.5
  • 159
    • 0141927282 scopus 로고    scopus 로고
    • Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression
    • Angelucci F, Aloe L, Jimenez-Vasquez P, Mathe AA. Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression. Int J Neuropsychopharmacol 2003; 6: 225-231.
    • (2003) Int J Neuropsychopharmacol , vol.6 , pp. 225-231
    • Angelucci, F.1    Aloe, L.2    Jimenez-Vasquez, P.3    Mathe, A.A.4
  • 160
    • 0025006686 scopus 로고
    • Carbamazepine and electroconvulsive shock attenuate beta-adrenoceptor and muscarinic cholinoceptor coupling to G proteins in rat cortex
    • Avissar S, Schreiber G, Aulakh CS, Wozniak KM, Murphy DL. Carbamazepine and electroconvulsive shock attenuate beta-adrenoceptor and muscarinic cholinoceptor coupling to G proteins in rat cortex. Eur J Pharmacol 1990; 189: 99-103.
    • (1990) Eur J Pharmacol , vol.189 , pp. 99-103
    • Avissar, S.1    Schreiber, G.2    Aulakh, C.S.3    Wozniak, K.M.4    Murphy, D.L.5
  • 161
    • 0033013011 scopus 로고    scopus 로고
    • A bimodal model of the mechanism of action of lithium
    • Jope RS. A bimodal model of the mechanism of action of lithium. Mol Psychiatry 1999; 4: 21-25.
    • (1999) Mol Psychiatry , vol.4 , pp. 21-25
    • Jope, R.S.1
  • 162
    • 0031973757 scopus 로고    scopus 로고
    • Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin
    • Kofman O, Li PP, Warsh JJ. Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin. Pharmacol Biochem Behav 1998; 59: 191-200.
    • (1998) Pharmacol Biochem Behav , vol.59 , pp. 191-200
    • Kofman, O.1    Li, P.P.2    Warsh, J.J.3
  • 163
    • 0030249233 scopus 로고    scopus 로고
    • Effects of valproic acid on beta-adrenergic receptors, G-proteins, and adenylyl cyclase in rat C6 glioma cells
    • Chen G, Manji HK, Wright CB, Hawver DB, Potter WZ. Effects of valproic acid on beta-adrenergic receptors, G-proteins, and adenylyl cyclase in rat C6 glioma cells. Neuropsychopharmacology 1996; 15: 271-280.
    • (1996) Neuropsychopharmacology , vol.15 , pp. 271-280
    • Chen, G.1    Manji, H.K.2    Wright, C.B.3    Hawver, D.B.4    Potter, W.Z.5
  • 164
    • 0018597959 scopus 로고
    • Changes in lymphocyte beta-adrenergic receptors in depression and mania
    • Extein I, Tallman J, Smith CC, Goodwin FK. Changes in lymphocyte beta-adrenergic receptors in depression and mania. Psychiatry Res 1979; 1: 191-197.
    • (1979) Psychiatry Res , vol.1 , pp. 191-197
    • Extein, I.1    Tallman, J.2    Smith, C.C.3    Goodwin, F.K.4
  • 165
    • 0022997635 scopus 로고
    • The cyclic AMP second messenger system in man: The effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification
    • Ebstein RP, Oppenheim G, Ebstein BS, Amiri Z, Stessman J. The cyclic AMP second messenger system in man: the effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification. Prog Neuropsychopharmacol Biol Psychiatry 1986; 10: 323-353.
    • (1986) Prog Neuropsychopharmacol Biol Psychiatry , vol.10 , pp. 323-353
    • Ebstein, R.P.1    Oppenheim, G.2    Ebstein, B.S.3    Amiri, Z.4    Stessman, J.5
  • 167
    • 0027401398 scopus 로고
    • CNS signal transduction in the pathophysiology and pharmacotherapy of affective disorders and schizophrenia
    • Hudson CJ, Young LT, Li PP, Warsh JJ. CNS signal transduction in the pathophysiology and pharmacotherapy of affective disorders and schizophrenia. Synapse 1993; 13: 278-293.
    • (1993) Synapse , vol.13 , pp. 278-293
    • Hudson, C.J.1    Young, L.T.2    Li, P.P.3    Warsh, J.J.4
  • 169
    • 0038717215 scopus 로고    scopus 로고
    • Isoform-specific regulation of adenylyl cyclase: A potential target in future pharmacotherapy
    • Iwatsubo K, Tsunematsu T, Ishikawa Y. Isoform-specific regulation of adenylyl cyclase: a potential target in future pharmacotherapy. Expert Opin Ther Targets 2003; 7: 441-451.
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 441-451
    • Iwatsubo, K.1    Tsunematsu, T.2    Ishikawa, Y.3
  • 170
    • 0034043203 scopus 로고    scopus 로고
    • CaM-kinases: Modulators of synaptic plasticity
    • Soderling TR. CaM-kinases: modulators of synaptic plasticity. Curr Opin Neurobiol 2000; 10: 375-380.
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 375-380
    • Soderling, T.R.1
  • 171
    • 0033570745 scopus 로고    scopus 로고
    • Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: Molecular transduction of mood stabilization in the treatment of manic-depressive illness
    • Manji HK, Lenox RH. Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness. Biol Psychiatry 1999; 46: 1328-1351.
    • (1999) Biol Psychiatry , vol.46 , pp. 1328-1351
    • Manji, H.K.1    Lenox, R.H.2
  • 172
    • 0034209028 scopus 로고    scopus 로고
    • The high affinity inositol transport system - Implications for the pathophysiology and treatment of bipolar disorder
    • van Calker D, Belmaker RH. The high affinity inositol transport system - implications for the pathophysiology and treatment of bipolar disorder. Bipolar Disord 2000; 2: 102-107.
    • (2000) Bipolar Disord , vol.2 , pp. 102-107
    • Van Calker, D.1    Belmaker, R.H.2
  • 173
    • 0032864255 scopus 로고    scopus 로고
    • Inhibition of the high affinity myo-inositol transport system: A common mechanism of action of antibipolar drugs?
    • Lubrich B, van Calker D. Inhibition of the high affinity myo-inositol transport system: a common mechanism of action of antibipolar drugs? Neuropsychopharmacology 1999; 21: 519-529.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 519-529
    • Lubrich, B.1    Van Calker, D.2
  • 174
    • 0037118050 scopus 로고    scopus 로고
    • A common mechanism of action for three mood-stabilizing drugs
    • Williams RS, Cheng L, Mudge AW, Harwood AJ. A common mechanism of action for three mood-stabilizing drugs. Nature 2002; 417: 292-295.
    • (2002) Nature , vol.417 , pp. 292-295
    • Williams, R.S.1    Cheng, L.2    Mudge, A.W.3    Harwood, A.J.4
  • 175
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992; 258: 607-614.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 176
    • 0030272375 scopus 로고    scopus 로고
    • Modulation of protein kinase C isozymes and substrates by lithium: The role of myo-inositol
    • Manji HK, Bersudsky Y, Chen G, Belmaker RH, Potter WZ. Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol. Neuropsychopharmacology 1996; 15: 370-381.
    • (1996) Neuropsychopharmacology , vol.15 , pp. 370-381
    • Manji, H.K.1    Bersudsky, Y.2    Chen, G.3    Belmaker, R.H.4    Potter, W.Z.5
  • 177
    • 0027366278 scopus 로고
    • Lithium decreases membrane-associated protein kinase C in hippocampus: Selectivity for the alpha isozyme
    • Manji HK, Etcheberrigaray R, Chen G, Olds JL. Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme. J Neurochem 1993; 61: 2303-2310.
    • (1993) J Neurochem , vol.61 , pp. 2303-2310
    • Manji, H.K.1    Etcheberrigaray, R.2    Chen, G.3    Olds, J.L.4
  • 178
    • 0028850086 scopus 로고
    • Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells
    • Li X, Jope RS. Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells. J Neurochem 1995; 65: 2500-2508.
    • (1995) J Neurochem , vol.65 , pp. 2500-2508
    • Li, X.1    Jope, R.S.2
  • 179
    • 0026567408 scopus 로고
    • Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
    • Lenox RH, Watson DG, Patel J, Ellis J. Chronic lithium administration alters a prominent PKC substrate in rat hippocampus. Brain Res 1992; 570: 333-340.
    • (1992) Brain Res , vol.570 , pp. 333-340
    • Lenox, R.H.1    Watson, D.G.2    Patel, J.3    Ellis, J.4
  • 180
    • 0030036555 scopus 로고    scopus 로고
    • Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: Potentiation by muscarinic receptor activation
    • Watson DG, Lenox RH. Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: potentiation by muscarinic receptor activation. J Neurochem 1996; 67: 767-777.
    • (1996) J Neurochem , vol.67 , pp. 767-777
    • Watson, D.G.1    Lenox, R.H.2
  • 181
    • 0027944371 scopus 로고
    • Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro
    • Chen G, Manji HK, Hawver DB, Wright CB, Potter WZ. Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro. J Neurochem 1994; 63: 2361-2364.
    • (1994) J Neurochem , vol.63 , pp. 2361-2364
    • Chen, G.1    Manji, H.K.2    Hawver, D.B.3    Wright, C.B.4    Potter, W.Z.5
  • 182
    • 0031981038 scopus 로고    scopus 로고
    • Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: A property of protein kinase C-mediated mood stabilizers
    • Watson DG, Watterson JM, Lenox RH. Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers. J Pharmacol Exp Ther 1998; 285: 307-316.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 307-316
    • Watson, D.G.1    Watterson, J.M.2    Lenox, R.H.3
  • 183
    • 0026533049 scopus 로고
    • Sensitization, kindling, and carbamazepine: An update on their implications for the course of affective illness
    • Post RM, Susan R, Weiss B. Sensitization, kindling, and carbamazepine: an update on their implications for the course of affective illness. Pharmacopsychiatry 1992; 25: 41-43.
    • (1992) Pharmacopsychiatry , vol.25 , pp. 41-43
    • Post, R.M.1    Susan, R.2    Weiss, B.3
  • 184
    • 0025776394 scopus 로고
    • Long-lasting enhancement of the membrane-associated protein kinase C activity in the hippocampal kindled rat
    • Daigen A, Akiyama K, Itoh T, Kohira I, Sora I, Morimoto K et al. Long-lasting enhancement of the membrane-associated protein kinase C activity in the hippocampal kindled rat. Jpn J Psychiatry Neurol 1991; 45: 297-301.
    • (1991) Jpn J Psychiatry Neurol , vol.45 , pp. 297-301
    • Daigen, A.1    Akiyama, K.2    Itoh, T.3    Kohira, I.4    Sora, I.5    Morimoto, K.6
  • 185
    • 0026787868 scopus 로고
    • Permanent increase in membrane-associated protein kinase C activity in the hippocampal kindled rat
    • Kohira I, Akiyama K, Daigen A, Itoh T, Ono M, Morimoto K et al. Permanent increase in membrane-associated protein kinase C activity in the hippocampal kindled rat. Jpn J Psychiatry Neurol 1992; 46: 510-512.
    • (1992) Jpn J Psychiatry Neurol , vol.46 , pp. 510-512
    • Kohira, I.1    Akiyama, K.2    Daigen, A.3    Itoh, T.4    Ono, M.5    Morimoto, K.6
  • 186
    • 0028101999 scopus 로고
    • Kindled amygdaloid seizures in rats cause immediate and transient increase in protein kinase C activity followed by transient suppression of the activity
    • Osonoe K, Ogata S, Iwata Y, Mori N. Kindled amygdaloid seizures in rats cause immediate and transient increase in protein kinase C activity followed by transient suppression of the activity. Epilepsia 1994; 35: 850-854.
    • (1994) Epilepsia , vol.35 , pp. 850-854
    • Osonoe, K.1    Ogata, S.2    Iwata, Y.3    Mori, N.4
  • 187
    • 0028068110 scopus 로고
    • Differential changes in the activities of multiple protein kinase C subspecies in the hippocampal-kindled rat
    • Ono M, Akiyama K, Tsutsui K, Kuroda S. Differential changes in the activities of multiple protein kinase C subspecies in the hippocampal-kindled rat. Brain Res 1994; 660: 27-33.
    • (1994) Brain Res , vol.660 , pp. 27-33
    • Ono, M.1    Akiyama, K.2    Tsutsui, K.3    Kuroda, S.4
  • 188
    • 0029019938 scopus 로고
    • Long-lasting increase in protein kinase C activity in the hippocampus of amygdala-kindled rat
    • Akiyama K, Ono M, Kohira I, Daigen A, Ishihara T, Kuroda S. Long-lasting increase in protein kinase C activity in the hippocampus of amygdala-kindled rat. Brain Res 1995; 679: 212-220.
    • (1995) Brain Res , vol.679 , pp. 212-220
    • Akiyama, K.1    Ono, M.2    Kohira, I.3    Daigen, A.4    Ishihara, T.5    Kuroda, S.6
  • 189
    • 0028846262 scopus 로고
    • Isozyme specific changes in the expression of protein kinase C isozyme (alpha-zeta) genes in the hippocampus of rats induced by kindling epileptogenesis
    • Kamphuis W, Hendriksen E, Lopes da Silva FH. Isozyme specific changes in the expression of protein kinase C isozyme (alpha-zeta) genes in the hippocampus of rats induced by kindling epileptogenesis. Brain Res 1995; 702: 94-100.
    • (1995) Brain Res , vol.702 , pp. 94-100
    • Kamphuis, W.1    Hendriksen, E.2    Lopes Da Silva, F.H.3
  • 190
    • 0026940934 scopus 로고
    • Amygdala kindling-induced seizures selectively impair spatial memory 1. Behavioral characteristics and effects on hippocampal neuronal protein kinase C isoforms
    • Beldhuis HJ, Everts HG, Van der Zee EA, Luiten PG, Bohus B. Amygdala kindling-induced seizures selectively impair spatial memory 1. Behavioral characteristics and effects on hippocampal neuronal protein kinase C isoforms. Hippocampus 1992; 2: 397-409.
    • (1992) Hippocampus , vol.2 , pp. 397-409
    • Beldhuis, H.J.1    Everts, H.G.2    Van Der Zee, E.A.3    Luiten, P.G.4    Bohus, B.5
  • 192
    • 0027015513 scopus 로고
    • Kindling-induced changes of protein kinase C levels in hippocampus and neocortex
    • Buzsaki G, Hsu M, Horvath Z, Horsburgh K, Sundsmo M, Masliah E et al. Kindling-induced changes of protein kinase C levels in hippocampus and neocortex. Epilepsy Res Suppl 1992; 9: 279-283; discussion 283-274.
    • (1992) Epilepsy Res Suppl , vol.9 , pp. 279-283
    • Buzsaki, G.1    Hsu, M.2    Horvath, Z.3    Horsburgh, K.4    Sundsmo, M.5    Masliah, E.6
  • 193
    • 0027221154 scopus 로고
    • Long-term increase in protein kinase C-gamma and muscarinic acetylcholine receptor expression in the cerebral cortex of amygdala-kindled rats - A quantitative immunocytochemical study
    • Beldhuis HJ, De Ruiter AJ, Maes FW, Suzuki T, Bohus B. Long-term increase in protein kinase C-gamma and muscarinic acetylcholine receptor expression in the cerebral cortex of amygdala-kindled rats - a quantitative immunocytochemical study. Neuroscience 1993; 55: 965-973.
    • (1993) Neuroscience , vol.55 , pp. 965-973
    • Beldhuis, H.J.1    De Ruiter, A.J.2    Maes, F.W.3    Suzuki, T.4    Bohus, B.5
  • 194
    • 0026621687 scopus 로고
    • Protein kinase C and dopamine transport - 2. Effects of amphetamine in vitro
    • Giambalvo CT. Protein kinase C and dopamine transport - 2. Effects of amphetamine in vitro. Neuropharmacology 1992; 31: 1211-1222.
    • (1992) Neuropharmacology , vol.31 , pp. 1211-1222
    • Giambalvo, C.T.1
  • 195
    • 0026715630 scopus 로고
    • Protein kinase C and dopamine transport - 1. Effects of amphetamine in vivo
    • Giambalvo CT. Protein kinase C and dopamine transport - 1. Effects of amphetamine in vivo. Neuropharmacology 1992; 31: 1201-1210.
    • (1992) Neuropharmacology , vol.31 , pp. 1201-1210
    • Giambalvo, C.T.1
  • 196
    • 0027385573 scopus 로고
    • Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine
    • Gnegy ME, Hong P, Ferrell ST. Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine. Brain Res Mol Brain Res 1993; 20: 289-298.
    • (1993) Brain Res Mol Brain Res , vol.20 , pp. 289-298
    • Gnegy, M.E.1    Hong, P.2    Ferrell, S.T.3
  • 197
    • 0031443572 scopus 로고    scopus 로고
    • Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine
    • Iwata SI, Hewlett GH, Ferrell ST, Kantor L, Gnegy ME. Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine. J Pharmacol Exp Ther 1997; 283: 1445-1452.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 1445-1452
    • Iwata, S.I.1    Hewlett, G.H.2    Ferrell, S.T.3    Kantor, L.4    Gnegy, M.E.5
  • 198
    • 0030910710 scopus 로고    scopus 로고
    • Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes
    • Iwata S, Hewlett GH, Gnegy ME. Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes. Synapse 1997; 26: 281-291.
    • (1997) Synapse , vol.26 , pp. 281-291
    • Iwata, S.1    Hewlett, G.H.2    Gnegy, M.E.3
  • 199
    • 0031933722 scopus 로고    scopus 로고
    • Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices
    • Kantor L, Gnegy ME. Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices. J Pharmacol Exp Ther 1998; 284: 592-598.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 592-598
    • Kantor, L.1    Gnegy, M.E.2
  • 200
    • 0027761105 scopus 로고
    • Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies
    • Steketee JD. Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: behavioral and in vivo microdialysis studies. Neuropharmacology 1993; 32: 1289-1297.
    • (1993) Neuropharmacology , vol.32 , pp. 1289-1297
    • Steketee, J.D.1
  • 201
    • 0028568329 scopus 로고
    • Intra-A10 injection of H7 blocks the development of sensitization to cocaine
    • Steketee JD. Intra-A10 injection of H7 blocks the development of sensitization to cocaine. Neuroreport 1994; 6: 69-72.
    • (1994) Neuroreport , vol.6 , pp. 69-72
    • Steketee, J.D.1
  • 202
    • 0026536597 scopus 로고
    • Mania in association with hydrocortisone replacement for Addison's disease
    • Ur E, Turner TH, Goodwin TJ, Grossman A, Besser GM. Mania in association with hydrocortisone replacement for Addison's disease. Postgrad Med J 1992; 68: 41-43.
    • (1992) Postgrad Med J , vol.68 , pp. 41-43
    • Ur, E.1    Turner, T.H.2    Goodwin, T.J.3    Grossman, A.4    Besser, G.M.5
  • 203
    • 0021995234 scopus 로고
    • Diagnostic categorization of psychiatric disturbance in Cushing's syndrome
    • Haskett RF. Diagnostic categorization of psychiatric disturbance in Cushing's syndrome. Am J Psychiatry 1985; 142: 911-916.
    • (1985) Am J Psychiatry , vol.142 , pp. 911-916
    • Haskett, R.F.1
  • 204
    • 0032924793 scopus 로고    scopus 로고
    • Administration of dexamethasone upregulates protein kinase C activity and the expression of gamma and epsilon protein kinase C isozymes in the rat brain
    • Dwivedi Y, Pandey GN. Administration of dexamethasone upregulates protein kinase C activity and the expression of gamma and epsilon protein kinase C isozymes in the rat brain. J Neurochem 1999; 72: 380-387.
    • (1999) J Neurochem , vol.72 , pp. 380-387
    • Dwivedi, Y.1    Pandey, G.N.2
  • 205
    • 0028288513 scopus 로고
    • The responsiveness of cerebral cortical adrenergic receptors after chronic administration of atypical antidepressant mianserin
    • Nalepa I, Vetulani J. The responsiveness of cerebral cortical adrenergic receptors after chronic administration of atypical antidepressant mianserin. J Psychiatry Neurosci 1994; 19: 120-128.
    • (1994) J Psychiatry Neurosci , vol.19 , pp. 120-128
    • Nalepa, I.1    Vetulani, J.2
  • 206
    • 0027817597 scopus 로고
    • The antagonistic effect of separate and consecutive chronic treatment with imipramine and ECS on the inhibition of alpha 1-adrenoceptor activity by protein kinase C
    • Nalepa I, Chalecka-Franaszek E, Vetulani J. The antagonistic effect of separate and consecutive chronic treatment with imipramine and ECS on the inhibition of alpha 1-adrenoceptor activity by protein kinase C. Pol J Pharmacol 1993; 45: 521-532.
    • (1993) Pol J Pharmacol , vol.45 , pp. 521-532
    • Nalepa, I.1    Chalecka-Franaszek, E.2    Vetulani, J.3
  • 207
    • 0032456140 scopus 로고    scopus 로고
    • Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins
    • Apparsundaram S, Schroeter S, Giovanetti E, Blakely RD. Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins. J Pharmacol Exp Ther 1998; 287: 744-751.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 744-751
    • Apparsundaram, S.1    Schroeter, S.2    Giovanetti, E.3    Blakely, R.D.4
  • 208
    • 0032465989 scopus 로고    scopus 로고
    • Acute regulation of norepinephrine transport: I. Protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells
    • Apparsundaram S, Galli A, DeFelice LJ, Hartzell HC, Blakely RD. Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells. J Pharmacol Exp Ther 1998; 287: 733-743.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 733-743
    • Apparsundaram, S.1    Galli, A.2    DeFelice, L.J.3    Hartzell, H.C.4    Blakely, R.D.5
  • 209
    • 0032146647 scopus 로고    scopus 로고
    • Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins
    • Blakely RD, Ramamoorthy S, Schroeter S, Qian Y, Apparsundaram S, Galli A et al. Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins. Biol Psychiatry 1998; 44: 169-178.
    • (1998) Biol Psychiatry , vol.44 , pp. 169-178
    • Blakely, R.D.1    Ramamoorthy, S.2    Schroeter, S.3    Qian, Y.4    Apparsundaram, S.5    Galli, A.6
  • 210
    • 0032528853 scopus 로고    scopus 로고
    • Expression and regulation of the human dopamine transporter in a neuronal cell line
    • Zhang L, Elmer LW, Little KY. Expression and regulation of the human dopamine transporter in a neuronal cell line. Brain Res Mol Brain Res 1998; 59: 66-73.
    • (1998) Brain Res Mol Brain Res , vol.59 , pp. 66-73
    • Zhang, L.1    Elmer, L.W.2    Little, K.Y.3
  • 212
    • 0022892593 scopus 로고
    • Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity
    • Horgan K, Cooke E, Hallett MB, Mansel RE. Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity. Biochem Pharmacol 1986; 35: 4463-4465.
    • (1986) Biochem Pharmacol , vol.35 , pp. 4463-4465
    • Horgan, K.1    Cooke, E.2    Hallett, M.B.3    Mansel, R.E.4
  • 213
    • 0023764676 scopus 로고
    • Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue
    • O'Brian CA, Housey GM, Weinstein IB. Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue. Cancer Res 1988; 48: 3626-3629.
    • (1988) Cancer Res , vol.48 , pp. 3626-3629
    • O'Brian, C.A.1    Housey, G.M.2    Weinstein, I.B.3
  • 214
    • 0036247969 scopus 로고    scopus 로고
    • Potential new medical therapies for diabetic retinopathy: Protein kinase C inhibitors
    • Frank RN. Potential new medical therapies for diabetic retinopathy: protein kinase C inhibitors. Am J Ophthalmol 2002; 133: 693-698.
    • (2002) Am J Ophthalmol , vol.133 , pp. 693-698
    • Frank, R.N.1
  • 215
    • 0037293351 scopus 로고    scopus 로고
    • Ruboxistaurin (Eli Lilly)
    • Wheeler GD. Ruboxistaurin (Eli Lilly). IDrugs 2003; 6: 159-163.
    • (2003) IDrugs , vol.6 , pp. 159-163
    • Wheeler, G.D.1
  • 216
    • 0036939182 scopus 로고    scopus 로고
    • The potential role of PKC beta in diabetic retinopathy and macular edema
    • Aiello LP. The potential role of PKC beta in diabetic retinopathy and macular edema. Surv Ophthalmol 2002; 47(Suppl 2): S263-S269.
    • (2002) Surv Ophthalmol , vol.47 , Issue.2 SUPPL.
    • Aiello, L.P.1
  • 217
    • 0032987224 scopus 로고    scopus 로고
    • Inhibition of protein kinase C-do we, can we, and should we?
    • Parker PJ. Inhibition of protein kinase C-do we, can we, and should we? Pharmacol Ther 1999; 82: 263-267.
    • (1999) Pharmacol Ther , vol.82 , pp. 263-267
    • Parker, P.J.1
  • 218
    • 4243187646 scopus 로고    scopus 로고
    • Neurotrophic signaling in mood disorders
    • Finkel T, Gutkind JS (eds). John Wiley & Sons, Inc.: Hoboken, NJ
    • Du J, Gould TD, Manji HK. Neurotrophic signaling in mood disorders. In: Finkel T, Gutkind JS (eds). Signal Transduction and Human Disease. John Wiley & Sons, Inc.: Hoboken, NJ, 2003 pp 411-446.
    • (2003) Signal Transduction and Human Disease , pp. 411-446
    • Du, J.1    Gould, T.D.2    Manji, H.K.3
  • 219
    • 0036460741 scopus 로고    scopus 로고
    • Selective chronic stress-induced in vivo accumulation of phospho-ERK1/2 in prefrontal dendrites: Implications for stress-related cortical pathology?
    • Trentani A, Ter Horst GJ, Kuipers SD, Den Boer JA. Selective chronic stress-induced in vivo accumulation of phospho-ERK1/2 in prefrontal dendrites: implications for stress-related cortical pathology? Eur J Neurosci 2002; 15: 1681-1691.
    • (2002) Eur J Neurosci , vol.15 , pp. 1681-1691
    • Trentani, A.1    Ter Horst, G.J.2    Kuipers, S.D.3    Den Boer, J.A.4
  • 221
    • 0035943699 scopus 로고    scopus 로고
    • The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
    • Yuan PX, Huang LD, Jiang YM, Gutkind JS, Manji HK, Chen G. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J Biol Chem 2001; 276: 31674-31683.
    • (2001) J Biol Chem , vol.276 , pp. 31674-31683
    • Yuan, P.X.1    Huang, L.D.2    Jiang, Y.M.3    Gutkind, J.S.4    Manji, H.K.5    Chen, G.6
  • 222
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen G, Zeng WZ, Yuan PX, Huang LD, Jiang YM, Zhao ZH et al. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem 1999; 72: 879-882.
    • (1999) J Neurochem , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.Z.2    Yuan, P.X.3    Huang, L.D.4    Jiang, Y.M.5    Zhao, Z.H.6
  • 223
    • 0036220487 scopus 로고    scopus 로고
    • PKC MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers
    • Manji HK, Chen G. PKC MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers. Mol Psychiatry 2002; 7(Suppl 1): S46-56.
    • (2002) Mol Psychiatry , vol.7 , Issue.1 SUPPL.
    • Manji, H.K.1    Chen, G.2
  • 224
    • 0035039841 scopus 로고    scopus 로고
    • Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: Long-term effects on cell survival and transcript stability
    • Chen G, Huang LD, Zeng WZ, Manji HK. Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: long-term effects on cell survival and transcript stability. Int J Neuropsychopharmacol 2001; 4: 47-64.
    • (2001) Int J Neuropsychopharmacol , vol.4 , pp. 47-64
    • Chen, G.1    Huang, L.D.2    Zeng, W.Z.3    Manji, H.K.4
  • 225
    • 0034589368 scopus 로고    scopus 로고
    • Histopathology of the prefrontal cortex in major depression: What does it tell us about dysfunctional monoaminergic circuits?
    • Rajkowska G. Histopathology of the prefrontal cortex in major depression: what does it tell us about dysfunctional monoaminergic circuits? Prog Brain Res 2000; 126: 397-412.
    • (2000) Prog Brain Res , vol.126 , pp. 397-412
    • Rajkowska, G.1
  • 226
    • 0037249456 scopus 로고    scopus 로고
    • Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism
    • Huang X, Wu DY, Chen G, Manji H, Chen DF. Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism. Invest Ophthalmol Vis Sci 2003; 44: 347-354.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 347-354
    • Huang, X.1    Wu, D.Y.2    Chen, G.3    Manji, H.4    Chen, D.F.5
  • 227
    • 0036914074 scopus 로고    scopus 로고
    • Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity
    • Hashimoto R, Takei N, Shimazu K, Christ L, Lu B, Chuang DM. Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity. Neuropharmacology 2002; 43: 1173-1179.
    • (2002) Neuropharmacology , vol.43 , pp. 1173-1179
    • Hashimoto, R.1    Takei, N.2    Shimazu, K.3    Christ, L.4    Lu, B.5    Chuang, D.M.6
  • 229
    • 0028970069 scopus 로고
    • Anticonvulsants attenuate amyloid beta-peptide neurotoxicity, Ca2+ deregulation, and cytoskeletal pathology
    • Mark RJ, Ashford JW, Goodman Y, Mattson MP. Anticonvulsants attenuate amyloid beta-peptide neurotoxicity, Ca2+ deregulation, and cytoskeletal pathology. Neurobiol Aging 1995; 16: 187-198.
    • (1995) Neurobiol Aging , vol.16 , pp. 187-198
    • Mark, R.J.1    Ashford, J.W.2    Goodman, Y.3    Mattson, M.P.4
  • 230
    • 0034667299 scopus 로고    scopus 로고
    • Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: Implications for the pathophysiology and treatment of manic-depressive illness
    • Manji HK, Moore GJ, Chen G. Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness. Biol Psychiatry 2000; 48: 740-754.
    • (2000) Biol Psychiatry , vol.48 , pp. 740-754
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 231
    • 0036328597 scopus 로고    scopus 로고
    • Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: Involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation
    • Hashimoto R, Hough C, Nakazawa T, Yamamoto T, Chuang DM. Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation. J Neurochem 2002; 80: 589-597.
    • (2002) J Neurochem , vol.80 , pp. 589-597
    • Hashimoto, R.1    Hough, C.2    Nakazawa, T.3    Yamamoto, T.4    Chuang, D.M.5
  • 233
    • 0036753235 scopus 로고    scopus 로고
    • Low glial numbers in the amygdala in major depressive disorder
    • Bowley MP, Drevets WC, Ongur D, Price JL. Low glial numbers in the amygdala in major depressive disorder. Biol Psychiatry 2002; 52: 404-412.
    • (2002) Biol Psychiatry , vol.52 , pp. 404-412
    • Bowley, M.P.1    Drevets, W.C.2    Ongur, D.3    Price, J.L.4
  • 234
    • 0028978925 scopus 로고
    • N-acetylaspartate in neuropsychiatric disorders
    • Tsai G, Coyle JT. N-acetylaspartate in neuropsychiatric disorders. Prog Neurobiol 1995; 46: 531-540.
    • (1995) Prog Neurobiol , vol.46 , pp. 531-540
    • Tsai, G.1    Coyle, J.T.2
  • 235
    • 18744435263 scopus 로고    scopus 로고
    • Lithium increases N-acetyl-aspartate in the human brain: In vivo evidence in support of bcl-2's neurotrophic effects?
    • Moore GJ, Bebchuk JM, Hasanat K, Chen G, Seraji-Bozorgzad N, Wilds IB et al. Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects? Biol Psychiatry 2000; 48: 1-8.
    • (2000) Biol Psychiatry , vol.48 , pp. 1-8
    • Moore, G.J.1    Bebchuk, J.M.2    Hasanat, K.3    Chen, G.4    Seraji-Bozorgzad, N.5    Wilds, I.B.6
  • 238
    • 0346034866 scopus 로고    scopus 로고
    • Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients
    • Silverstone PH, Wu RH, O'Donnell T, Ulrich M, Asghar SJ, Hanstock CC. Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients. Int Clin Psychopharmacol 2003; 18: 73-79.
    • (2003) Int Clin Psychopharmacol , vol.18 , pp. 73-79
    • Silverstone, P.H.1    Wu, R.H.2    O'Donnell, T.3    Ulrich, M.4    Asghar, S.J.5    Hanstock, C.C.6
  • 239
    • 0038050597 scopus 로고    scopus 로고
    • Neurotrophic effects of electroconvulsive therapy: A proton magnetic resonance study of the left amygdalar region in patients with treatment-resistant depression
    • Michael N, Erfurth A, Ohrmann P, Arolt V, Heindel W, Pfleiderer B. Neurotrophic effects of electroconvulsive therapy: a proton magnetic resonance study of the left amygdalar region in patients with treatment-resistant depression. Neuropsychopharmacology 2003; 28: 720-725.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 720-725
    • Michael, N.1    Erfurth, A.2    Ohrmann, P.3    Arolt, V.4    Heindel, W.5    Pfleiderer, B.6
  • 241
    • 0034208461 scopus 로고    scopus 로고
    • A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis
    • Ochs G, Penn RD, York M, Giess R, Beck M, Tonn J et al. A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000; 1: 201-206.
    • (2000) Amyotroph Lateral Scler Other Motor Neuron Disord , vol.1 , pp. 201-206
    • Ochs, G.1    Penn, R.D.2    York, M.3    Giess, R.4    Beck, M.5    Tonn, J.6
  • 242
    • 0034725743 scopus 로고    scopus 로고
    • Increase of bcl-2 protein in neuronal dendritic processes of cerebral cortex and hippocampus by the antiparkinsonian drugs, talipexole and pramipexole
    • Takata K, Kitamura Y, Kakimura J, Kohno Y, Taniguchi T. Increase of bcl-2 protein in neuronal dendritic processes of cerebral cortex and hippocampus by the antiparkinsonian drugs, talipexole and pramipexole. Brain Res 2000; 872: 236-241.
    • (2000) Brain Res , vol.872 , pp. 236-241
    • Takata, K.1    Kitamura, Y.2    Kakimura, J.3    Kohno, Y.4    Taniguchi, T.5
  • 243
    • 0033862666 scopus 로고    scopus 로고
    • Pramipexole augmentation in the treatment of unipolar and bipolar depression: A retrospective chart review
    • Sporn J, Ghaemi SN, Sambur MR, Rankin MA, Recht J, Sachs GS et al. Pramipexole augmentation in the treatment of unipolar and bipolar depression: a retrospective chart review. Ann Clin Psychiatry 2000; 12: 137-140.
    • (2000) Ann Clin Psychiatry , vol.12 , pp. 137-140
    • Sporn, J.1    Ghaemi, S.N.2    Sambur, M.R.3    Rankin, M.A.4    Recht, J.5    Sachs, G.S.6
  • 245
    • 1542313961 scopus 로고    scopus 로고
    • A preliminary randomized, double-blind, placebo-controlled trial of primapexole added to mood stabilizers for treatment-resistant bipolar depression
    • Goldberg JF, Burdick KE, Endick CJ. A preliminary randomized, double-blind, placebo-controlled trial of primapexole added to mood stabilizers for treatment-resistant bipolar depression. Am J Psychiatry 2004; 161: 564-566.
    • (2004) Am J Psychiatry , vol.161 , pp. 564-566
    • Goldberg, J.F.1    Burdick, K.E.2    Endick, C.J.3
  • 246
    • 0023828843 scopus 로고
    • Receptor-mediated activation of phospholipase A2 via GTP-binding proteins: Arachidonic acid and its metabolites as second messengers
    • Axelrod J, Burch RM, Jelsema CL. Receptor-mediated activation of phospholipase A2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers. Trends Neurosci 1988; 11: 117-123.
    • (1988) Trends Neurosci , vol.11 , pp. 117-123
    • Axelrod, J.1    Burch, R.M.2    Jelsema, C.L.3
  • 247
    • 0034912915 scopus 로고    scopus 로고
    • In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling
    • Rapoport SI. In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling. J Mol Neurosci 2001; 16: 243-261; discussion 279-284.
    • (2001) J Mol Neurosci , vol.16 , pp. 243-261
    • Rapoport, S.I.1
  • 248
    • 0028985121 scopus 로고
    • Phospholipase A2 and G proteins
    • Axelrod J. Phospholipase A2 and G proteins. Trends Neurosci 1995; 18: 64-65.
    • (1995) Trends Neurosci , vol.18 , pp. 64-65
    • Axelrod, J.1
  • 249
    • 0035010364 scopus 로고    scopus 로고
    • Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: A possible common effect of mood stabilizers
    • Chang MC, Contreras MA, Rosenberger TA, Rintala JJ, Bell JM, Rapoport SI. Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: a possible common effect of mood stabilizers. J Neurochem 2001; 77: 796-803.
    • (2001) J Neurochem , vol.77 , pp. 796-803
    • Chang, M.C.1    Contreras, M.A.2    Rosenberger, T.A.3    Rintala, J.J.4    Bell, J.M.5    Rapoport, S.I.6
  • 251
    • 0036301389 scopus 로고    scopus 로고
    • Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?
    • Rapoport SI, Bosetti F. Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? Arch Gen Psychiatry 2002; 59: 592-596.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 592-596
    • Rapoport, S.I.1    Bosetti, F.2
  • 252
    • 0031954923 scopus 로고    scopus 로고
    • Chronic lithium treatment decreases brain phospholipase A2 activity
    • Chang MC, Jones CR. Chronic lithium treatment decreases brain phospholipase A2 activity. Neurochem Res 1998; 23: 887-892.
    • (1998) Neurochem Res , vol.23 , pp. 887-892
    • Chang, M.C.1    Jones, C.R.2
  • 254
    • 0036385734 scopus 로고    scopus 로고
    • Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E(2) concentration in rat brain
    • Bosetti F, Rintala J, Seemann R, Rosenberger TA, Contreras MA, Rapoport SI et al. Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E(2) concentration in rat brain. Mol Psychiatry 2002; 7: 845-850.
    • (2002) Mol Psychiatry , vol.7 , pp. 845-850
    • Bosetti, F.1    Rintala, J.2    Seemann, R.3    Rosenberger, T.A.4    Contreras, M.A.5    Rapoport, S.I.6
  • 255
    • 0038673579 scopus 로고    scopus 로고
    • Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain
    • Bosetti F, Weerasinghe GR, Rosenberger TA, Rapoport SI. Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. J Neurochem 2003; 85: 690-696.
    • (2003) J Neurochem , vol.85 , pp. 690-696
    • Bosetti, F.1    Weerasinghe, G.R.2    Rosenberger, T.A.3    Rapoport, S.I.4
  • 257
    • 0037006014 scopus 로고    scopus 로고
    • Evidence for the involvement of cyclooxygenase activity in the development of cocaine sensitization
    • Reid MS, Ho LB, Hsu K, Fox L, Tolliver BK, Adams JU et al. Evidence for the involvement of cyclooxygenase activity in the development of cocaine sensitization. Pharmacol Biochem Behav 2002; 71: 37-54.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 37-54
    • Reid, M.S.1    Ho, L.B.2    Hsu, K.3    Fox, L.4    Tolliver, B.K.5    Adams, J.U.6


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