Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3′-phosphoadenosine-5′-phosphate phosphatase activities: A novel target of lithium therapy

Journal of Molecular Biology

Volumn 315, Issue 4, 2002, Pages 677-685

  Patel, S ^a   Yenush, L ^b   Rodriguez P L ^b   Serrano, R ^b   Blundell, T L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Ciudad Politécnica de la Innovación   (Spain)

Author keywords

3 phosphoadenosine 5 phosphate; Inositol; Lithium; Protein crystallography; Sulphation

Indexed keywords

3' PHOSPHOADENOSINE 5' PHOSPHATE PHOSPHATASE; ADENOSINE PHOSPHATE; ENZYME; INOSITOL; INOSITOL 1,4 BIPHOSPHATE; INOSITOL 4' PHOSPHATE; INOSITOL MONOPHOSPHATASE; INOSITOL POLYPHOSPHATE 1 PHOSPHATASE; LITHIUM; LITHIUM ION; MAGNESIUM ION; PHOSPHATASE; PHOSPHATE; PROTEIN; SULFOTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME STRUCTURE; HYDROLYSIS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RNA PROCESSING; STRUCTURE ANALYSIS; SULFATION;

RATTUS; RATTUS NORVEGICUS;

EID: 0036305698     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5271     Document Type: Article

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