Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists

British Journal of Pharmacology

Volumn 122, Issue 6, 1997, Pages 1202-1208

  Maemoto, Takuya ^a   Finlayson, Keith ^a   Olverman, Henry J ^a   Akahane, Atsushi ^b   Horton, Roger W ^c   Butcher, Steven P ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ASTELLAS PHARMA INC   (Japan)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

3H CGS 21680; 3H DPCPX; Adenosine receptors; Brain; FK453; Radioligand binding

Indexed keywords

1 [3 (2 PHENYLPYRAZOLO[1,5 A]PYRIDIN 3 YL)ACRYLOYL]PIPERIDINE 2 ACETIC ACID; 2 (2 HYDROXYETHYL) 1 [3 (2 PHENYLPYRAZOLO[1,5 A]PYRIDIN 3 YL)ACRYLOYL]PIPERIDINE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 CHLORO 6 N CYCLOPENTYLADENOSINE; 6 OXO 3 (2 PHENYLPYRAZOLO[1,5 A]PYRIDIN 3 YL) 1(6H) PYRIDAZINEBUTYRIC ACID; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; RADIOLIGAND; UNCLASSIFIED DRUG;

ADULT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN CORTEX; CLINICAL ARTICLE; GUINEA PIG; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; LIGAND BINDING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE;

ADENOSINE; ANIMALS; BINDING SITES; BRAIN; GUINEA PIGS; HUMANS; MALE; MICE; MIDDLE AGED; PHENETHYLAMINES; PYRIDINES; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P1; SPECIES SPECIFICITY; TRITIUM; XANTHINES;

EID: 0030777011     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701465     Document Type: Article

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