-
1
-
-
0037126181
-
Rotenone destroys dopa-minergic neurons and induces parkinsonian symptoms in rats
-
Alam M and WJ Schmidt (2002) Rotenone destroys dopa-minergic neurons and induces parkinsonian symptoms in rats. Behav. Brain Res. 136(1), 317-324.
-
(2002)
Behav. Brain Res.
, vol.136
, Issue.1
, pp. 317-324
-
-
Alam, M.1
Schmidt, W.J.2
-
2
-
-
10744224738
-
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
-
Bandopadhyay R, AE Kingsbury, MR Cookson, AR Reid, IM Evans, AD Hope, AM Pittman, T Lashley, R Canet-Aviles, DW Miller, C McLendon, C Strand, AJ Leonard, PM Abou-Sleiman, DG Healy, H Ariga, NW Wood, R de Silva, T Revesz, JA Hardy and AJ Lees (2004) The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. Brain 127(Pt. 2), 420-430.
-
(2004)
Brain
, vol.127
, Issue.PART 2
, pp. 420-430
-
-
Bandopadhyay, R.1
Kingsbury, A.E.2
Cookson, M.R.3
Reid, A.R.4
Evans, I.M.5
Hope, A.D.6
Pittman, A.M.7
Lashley, T.8
Canet-Aviles, R.9
Miller, D.W.10
McLendon, C.11
Strand, C.12
Leonard, A.J.13
Abou-Sleiman, P.M.14
Healy, D.G.15
Ariga, H.16
Wood, N.W.17
Silva, R.18
de Revesz, T.19
Hardy, J.A.20
Lees, A.J.21
more..
-
3
-
-
33745612296
-
Intersecting pathways to neurodegeneration in Parkinson's disease, effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system
-
Betarbet R, RM Canet-Aviles, TB Sherer, PG Mastroberardino, C McLendon, JH Kim, S Lund, HM Na, G Taylor, NF Bence, R Kopito, BB Seo, T Yagi, A Yagi, G Klinefelter, MR Cookson and JT Greenamyre (2006) Intersecting pathways to neurodegeneration in Parkinson's disease, effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiol. Dis. 22(2), 404-420.
-
(2006)
Neurobiol. Dis.
, vol.22
, Issue.2
, pp. 404-420
-
-
Betarbet, R.1
Canet-Aviles, R.M.2
Sherer, T.B.3
Mastroberardino, P.G.4
McLendon, C.5
Kim, J.H.6
Lund, S.7
Na, H.M.8
Taylor, G.9
Bence, N.F.10
Kopito, R.11
Seo, B.B.12
Yagi, T.13
Yagi, A.14
Klinefelter, G.15
Cookson, M.R.16
Greenamyre, J.T.17
-
4
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R, TB Sherer, G MacKenzie, M Garcia-Osuna, AV Panov and JT Greenamyre (2000) Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3(12), 1301-1306.
-
(2000)
Nat. Neurosci.
, vol.3
, Issue.12
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
5
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V, P Rizzu, MJ van Baren, O Schaap, GJ Breedveld, E Krieger, MC Dekker, F Squitieri, P Ibanez, M Joosse, JW van Dongen, N Vanacore, JC van Swieten, A Brice, G Meco, CM van Duijn, BA Oostra and P Heutink (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299 (5604), 256-259.
-
(2003)
Science
, vol.299
, Issue.5604
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
van Dongen, J.W.11
Vanacore, N.12
Swieten, J.C.13
van Brice, A.14
Meco, G.15
van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
6
-
-
15544377077
-
Redox cycling of the herbicide paraquat in microglial cultures
-
Bonneh-Barkay D, SH Reaney, JW Langston and DA Di Monte (2005) Redox cycling of the herbicide paraquat in microglial cultures. Brain Res. Mol. Brain Res. 134(1), 52-56.
-
(2005)
Brain Res. Mol. Brain Res.
, vol.134
, Issue.1
, pp. 52-56
-
-
Bonneh-Barkay, D.1
Reaney, S.H.2
Langston, J.W.3
Di Monte, D.A.4
-
7
-
-
0033608811
-
Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss
-
Brooks AI, CA Chadwick, HA Gelbard, DA Cory-Slechta and HJ Federoff (1999) Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss. Brain Res. 823(1-2), 1-10.
-
(1999)
Brain Res.
, vol.823
, Issue.1-2
, pp. 1-10
-
-
Brooks, A.I.1
Chadwick, C.A.2
Gelbard, H.A.3
Cory-Slechta, D.A.4
Federoff, H.J.5
-
8
-
-
0001496694
-
A primate model of parkinsonism, selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Burns RS, CC Chiueh, SP Markey, MH Ebert, DM Jacobowitz and IJ Kopin (1983) A primate model of parkinsonism, selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. Natl. Acad. Sci. USA 80, 4546-4550.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 4546-4550
-
-
Burns, R.S.1
Chiueh, C.C.2
Markey, S.P.3
Ebert, M.H.4
Jacobowitz, D.M.5
Kopin, I.J.6
-
9
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Aviles RM, MA Wilson, DW Miller, R Ahmad, C McLendon, S Bandyopadhyay, MJ Baptista, D Ringe, GA Petsko and MR Cookson (2004) The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. USA 101(24), 9103-9108.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.24
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
10
-
-
33646114508
-
Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline
-
Casarejos MJ, J Menendez, RM Solano, JA Rodriguez-Navarro, J Garcia de Yebenes and MA Mena (2006) Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline. J. Neurochem. 97(4), 934-946.
-
(2006)
J. Neurochem.
, vol.97
, Issue.4
, pp. 934-946
-
-
Casarejos, M.J.1
Menendez, J.2
Solano, R.M.3
Rodriguez-Navarro, J.A.4
Garcia de Yebenes, J.5
Mena, M.A.6
-
11
-
-
0027321004
-
2-deoxyglucose enhances 1-methyl-4-pheny1-1, 2,3,6-tetrahydropyridine-induced ATP loss in the mouse brain
-
Chan P, JW Langston, I Irwin, LE DeLanney and DA Di Monte (1993) 2-deoxyglucose enhances 1-methyl-4-pheny1-1, 2,3,6-tetrahydropyridine-induced ATP loss in the mouse brain. J. Neurochem. 61(2), 610-616.
-
(1993)
J. Neurochem.
, vol.61
, Issue.2
, pp. 610-616
-
-
Chan, P.1
Langston, J.W.2
Irwin, I.3
DeLanney, L.E.4
Di Monte, D.A.5
-
12
-
-
27544507306
-
Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration
-
Chandra S, G Gallardo, R Fernandez-Chacon, OM Schluter and TC Sudhof (2005) Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell 123(3), 383-396.
-
(2005)
Cell
, vol.123
, Issue.3
, pp. 383-396
-
-
Chandra, S.1
Gallardo, G.2
Fernandez-Chacon, R.3
Schluter, O.M.4
Sudhof, T.C.5
-
13
-
-
4644290985
-
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
-
Chartier-Harlin MC, J Kachergus, C Roumier, V Mouroux, X Douay, S Lincoln, C Levecque, L Larvor, J Andrieux, M Hullihan, N Waucquier, L Defebyre, P Amouyel, M Farrer and A Destee (2004) Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 364(9440), 1167-1169.
-
(2004)
Lancet
, vol.364
, Issue.9440
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hullihan, M.10
Waucquier, N.11
Defebyre, L.12
Amouyel, P.13
Farrer, M.14
Destee, A.15
-
14
-
-
20444367300
-
Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice
-
Chen L, B Cagniard, T Matthews, S Jones, HC Koh, Y Ding, PM Carvey, Z Ling, UJ Kang and X Zhuang (2005) Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice. J. Biol. Chem. 280(22), 21418-21426.
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.22
, pp. 21418-21426
-
-
Chen, L.1
Cagniard, B.2
Matthews, T.3
Jones, S.4
Koh, H.C.5
Ding, Y.6
Carvey, P.M.7
Ling, Z.8
Kang, U.J.9
Zhuang, X.10
-
15
-
-
10444253306
-
Parkin and Hsp70 sacked by BAG5
-
Chung KK and TM Dawson (2004) Parkin and Hsp70 sacked by BAG5. Neuron 44(6), 899-901.
-
(2004)
Neuron
, vol.44
, Issue.6
, pp. 899-901
-
-
Chung, K.K.1
Dawson, T.M.2
-
16
-
-
2542534741
-
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function
-
Chung KK, B Thomas, X Li, O Pletnikova, JC Troncoso, L Marsh, VL Dawson and TM Dawson (2004) S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science 304(5675), 1328-13231.
-
(2004)
Science
, vol.304
, Issue.5675
, pp. 1328-13231
-
-
Chung, K.K.1
Thomas, B.2
Li, X.3
Pletnikova, O.4
Troncoso, J.C.5
Marsh, L.6
Dawson, V.L.7
Dawson, T.M.8
-
17
-
-
0026598930
-
Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium, evidence for free radical involvement
-
Cleeter MW, JM Cooper and AH Schapira (1992) Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium, evidence for free radical involvement. J. Neurochem. 58(2), 786-789.
-
(1992)
J. Neurochem.
, vol.58
, Issue.2
, pp. 786-789
-
-
Cleeter, M.W.1
Cooper, J.M.2
Schapira, A.H.3
-
18
-
-
1842563080
-
Abnormal α-synuclein interactions with Rab proteins in α-synuclein A30P transgenic mice
-
Dalfo E, T Gomez-Isla, JL Rosa, M Nieto Bodelon, M Cuadrado Tejedor, M Barrachina, S Ambrosio and I Ferrer (2004) Abnormal α-synuclein interactions with Rab proteins in α-synuclein A30P transgenic mice. J. Neuropathol. Exp. Neurol. 63(4), 302-313.
-
(2004)
J. Neuropathol. Exp. Neurol.
, vol.63
, Issue.4
, pp. 302-313
-
-
Dalfo, E.1
Gomez-Isla, T.2
Rosa, J.L.3
Nieto Bodelon, M.4
Cuadrado Tejedor, M.5
Barrachina, M.6
Ambrosio, S.7
Ferrer, I.8
-
19
-
-
0023896746
-
Energy-driven uptake of the neurotoxin 1-methyl-4-phenylpyridinium into chromaffin granules via the catecholamine transporter
-
Daniels AJ and JF Reinhard Jr (1988) Energy-driven uptake of the neurotoxin 1-methyl-4-phenylpyridinium into chromaffin granules via the catecholamine transporter. J. Biol. Chem. 263(11), 5034-5036.
-
(1988)
J. Biol. Chem.
, vol.263
, Issue.11
, pp. 5034-5036
-
-
Daniels, A.J.1
Reinhard Jr., J.F.2
-
20
-
-
0037195109
-
Resistance of alpha-synuclein null mice to the parkinsonian neurotoxin MPTP
-
Dauer W, N Kholodilov, M Vila, AC Trillat, R Goodchild, KE Larsen, R Staal, K Tieu, Y Schmitz, CA Yuan, M Rocha, V Jackson-Lewis, S Hersch, D Sulzer, S Przedborski, R Burke and R Hen (2002) Resistance of alpha-synuclein null mice to the parkinsonian neurotoxin MPTP. Proc. Natl. Acad. Sci. USA 99(22), 14524-14529.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.22
, pp. 14524-14529
-
-
Dauer, W.1
Kholodilov, N.2
Vila, M.3
Trillat, A.C.4
Goodchild, R.5
Larsen, K.E.6
Staal, R.7
Tieu, K.8
Schmitz, Y.9
Yuan, C.A.10
Rocha, M.11
Jackson-Lewis, V.12
Hersch, S.13
Sulzer, D.14
Przedborski, S.15
Burke, R.16
Hen, R.17
-
21
-
-
3542993306
-
Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration
-
Drolet RE, B Behrouz, KJ Lookingland and JL Goudreau (2004) Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration. Neurotoxicology 25 (5), 761-769.
-
(2004)
Neurotoxicology
, vol.25
, Issue.5
, pp. 761-769
-
-
Drolet, R.E.1
Behrouz, B.2
Lookingland, J.K.3
Goudreau, J.L.4
-
22
-
-
0036934244
-
Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred
-
Duda JE, BI Giasson, ME Mabon, DC Miller, LI Golbe, VM Lee and JQ Trojanowski (2002) Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred. Acta Neuropathol. (Berl.) 104(1), 7-11.
-
(2002)
Acta Neuropathol. (Berl.)
, vol.104
, Issue.1
, pp. 7-11
-
-
Duda, J.E.1
Giasson, B.I.2
Mabon, M.E.3
Miller, D.C.4
Golbe, L.I.5
Lee, V.M.6
Trojanowski, J.Q.7
-
23
-
-
0034848395
-
Lewy bodies and parkinsonism in families with parkin mutations
-
Farrer M, P Chan, R Chen, L Tan, S Lincoln, D Hernandez, L Forno, K Gwinn-Hardy, L Petrucelli, J Hussey, A Singleton, C Tanner, J Hardy and JW Langston (2001) Lewy bodies and parkinsonism in families with parkin mutations. Ann. Neurol. 50 (3), 293-300.
-
(2001)
Ann. Neurol.
, vol.50
, Issue.3
, pp. 293-300
-
-
Farrer, M.1
Chan, P.2
Chen, R.3
Tan, L.4
Lincoln, S.5
Hernandez, D.6
Forno, L.7
Gwinn-Hardy, K.8
Petrucelli, L.9
Hussey, J.10
Singleton, A.11
Tanner, C.12
Hardy, J.13
Langston, J.W.14
-
24
-
-
0033677633
-
Linkage exclusion in French families with probable Parkinson's disease
-
Farrer M, T Destee, E Becquet, F Wavrant-De Vrieze, V Mouroux, F Richard, L Defebvre, S Lincoln, J Hardy, P Amouyel and MC Chartier-Harlin (2000) Linkage exclusion in French families with probable Parkinson's disease. Mov. Disord. 15 (6), 1075-1083.
-
(2000)
Mov. Disord.
, vol.15
, Issue.6
, pp. 1075-1083
-
-
Farrer, M.1
Destee, T.2
Becquet, E.3
Wavrant-De Vrieze, F.4
Mouroux, V.5
Richard, F.6
Defebvre, L.7
Lincoln, S.8
Hardy, J.9
Amouyel, P.10
Chartier-Harlin, M.C.11
-
25
-
-
10744227740
-
Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications
-
Farrer M, J Kachergus, L Forno, S Lincoln, DS Wang, M Hulihan, D Maraganore, K Gwinn-Hardy, Z Wszolek, D Dickson and JW Langston (2004) Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications. Ann. Neurol. 55(2), 174-179.
-
(2004)
Ann. Neurol.
, vol.55
, Issue.2
, pp. 174-179
-
-
Farrer, M.1
Kachergus, J.2
Forno, L.3
Lincoln, S.4
Wang, D.S.5
Hulihan, M.6
Maraganore, D.7
Gwinn-Hardy, K.8
Wszolek, Z.9
Dickson, D.10
Langston, J.W.11
-
26
-
-
0031005815
-
Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra
-
Ferrante RJ, JB Schulz, NW Kowall and MF Beal (1997) Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Res. 753(1), 157-162.
-
(1997)
Brain Res.
, vol.753
, Issue.1
, pp. 157-162
-
-
Ferrante, R.J.1
Schulz, J.B.2
Kowall, N.W.3
Beal, M.F.4
-
27
-
-
7044270767
-
Early and progressive sensorimotor anomalies in mice overex-pressing wild-type human α-synuclein
-
Fleming SM, J Salcedo, PO Fernagut, E Rockenstein, E Masliah, MS Levine and MF Chesselet (2004) Early and progressive sensorimotor anomalies in mice overex-pressing wild-type human α-synuclein. J. Neurosci. 24, 9434-9440.
-
(2004)
J. Neurosci.
, vol.24
, pp. 9434-9440
-
-
Fleming, S.M.1
Salcedo, J.2
Fernagut, P.O.3
Rockenstein, E.4
Masliah, E.5
Levine, M.S.6
Chesselet, M.F.7
-
28
-
-
10444238568
-
Similarities between methamphetamine toxicity and proteasome inhibition
-
Fornai F, P Lenzi, M Gesi, M Ferrucci, G Lazzeri, L Capobianco, A de Blasi, G Battaglia, F Nicoletti, S Ruggieri and A Paparelli (2004) Similarities between methamphetamine toxicity and proteasome inhibition. Ann. NY Acad. Sci. 1025, 162-170.
-
(2004)
Ann. NY Acad. Sci.
, vol.1025
, pp. 162-170
-
-
Fornai, F.1
Lenzi, P.2
Gesi, M.3
Ferrucci, M.4
Lazzeri, G.5
Capobianco, L.6
de Blasi, A.7
Battaglia, G.8
Nicoletti, F.9
Ruggieri, S.10
Paparelli, A.11
-
29
-
-
20044385568
-
Parkinson-like syndrome induced by continuous MPTP infusion, convergent roles of the ubiq-uitin-proteasome system and alpha-synuclein
-
Fornai F, OM Schluter, P Lenzi, M Gesi, R Ruffoli, M Ferrucci, G Lazzeri, CL Busceti, F Pontarelli, G Battaglia, A Pellegrini, F Nicoletti, S Ruggieri, A Paparelli and TC Sudhof (2005) Parkinson-like syndrome induced by continuous MPTP infusion, convergent roles of the ubiq-uitin-proteasome system and alpha-synuclein. Proc. Natl. Acad. Sci. USA 102(9), 3413-8.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.9
, pp. 3413-3418
-
-
Fornai, F.1
Schluter, O.M.2
Lenzi, P.3
Gesi, M.4
Ruffoli, R.5
Ferrucci, M.6
Lazzeri, G.7
Busceti, C.L.8
Pontarelli, F.9
Battaglia, G.10
Pellegrini, A.11
Nicoletti, F.12
Ruggieri, S.13
Paparelli, A.14
Sudhof, T.C.15
-
30
-
-
0022466381
-
Locus ceruleus lesions and eosinophilic inclusions in MPTP-treated monkeys
-
Forno LS, JW Langston, LE DeLanney, I Irwin and GA Ricaurte (1986) Locus ceruleus lesions and eosinophilic inclusions in MPTP-treated monkeys. Ann. Neurol. 20(4), 449-455.
-
(1986)
Ann. Neurol.
, vol.20
, Issue.4
, pp. 449-455
-
-
Forno, L.S.1
Langston, J.W.2
DeLanney, L.E.3
Irwin, I.4
Ricaurte, G.A.5
-
31
-
-
34147109175
-
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication
-
Jan. 24; [Epub ahead of print]
-
Fuchs J, C Nilsson, J Kachergus, M Munz, EM Larsson, B Schule, JW Langston, FA Middleton, OA Ross, M Hulihan, T Gasser and MJ Farrer (2007) Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication. Neurology 2007 Jan. 24; [Epub ahead of print]
-
(2007)
Neurology
, vol.2007
-
-
Fuchs, J.1
Nilsson, C.2
Kachergus, J.3
Munz, M.4
Larsson, E.M.5
Schule, B.6
Langston, J.W.7
Middleton, F.A.8
Ross, O.A.9
Hulihan, M.10
Gasser, T.11
Farrer, M.J.12
-
32
-
-
33845961057
-
Association of tau haplotype-tagging polymorphisms with Parkinson's disease in diverse ethnic Parkinson's disease cohorts
-
Fung HC, G Xiromerisiou, JR Gibbs, YR Wu, J Eerola, V Gourbali, O Hellstrom, CM Chen, J Duckworth, A Papadimitriou, PJ Tienari, GM Hadjigeorgiou, J Hardy and AB Singleton (2006) Association of tau haplotype-tagging polymorphisms with Parkinson's disease in diverse ethnic Parkinson's disease cohorts. Neurodegen. Dis. 3(6), 327-333.
-
(2006)
Neurodegen. Dis.
, vol.3
, Issue.6
, pp. 327-333
-
-
Fung, H.C.1
Xiromerisiou, G.2
Gibbs, J.R.3
Wu, Y.R.4
Eerola, J.5
Gourbali, V.6
Hellstrom, O.7
Chen, C.M.8
Duckworth, J.9
Papadimitriou, A.10
Tienari, P.J.11
Hadjigeorgiou, G.M.12
Hardy, J.13
Singleton, A.B.14
-
33
-
-
0031959343
-
Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice
-
Gainetdinov RR, F Fumagalli, YM Wang, SR Jones, AI Levey, GW Miller and MG Caron (1998) Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. J. Neurochem. 70 (5), 1973-1978.
-
(1998)
J. Neurochem.
, vol.70
, Issue.5
, pp. 1973-1978
-
-
Gainetdinov, R.R.1
Fumagalli, F.2
Wang, Y.M.3
Jones, S.R.4
Levey, A.I.5
Miller, G.W.6
Caron, M.G.7
-
34
-
-
0035109738
-
Synuclein-opathies, clinical and pathological implications
-
Galvin JE, VM Lee and JQ Trojanowski (2001) Synuclein-opathies, clinical and pathological implications. Arch. Neurol. 58(2), 186-190.
-
(2001)
Arch. Neurol.
, vol.58
, Issue.2
, pp. 186-190
-
-
Galvin, J.E.1
Lee, V.M.2
Trojanowski, J.Q.3
-
35
-
-
0026492005
-
Disease-specific patterns of locus coeruleus cell loss
-
German DC, KF Manaye, CL White 3rd, DJ Woodward, DD McIntire, WK Smith, RN Kalaria and DM Mann (1992) Disease-specific patterns of locus coeruleus cell loss. Ann. Neurol. 32(5), 667-676.
-
(1992)
Ann. Neurol.
, vol.32
, Issue.5
, pp. 667-676
-
-
German, D.C.1
Manaye, K.F.2
White III, C.L.3
Woodward, D.J.4
McIntire, D.D.5
Smith, W.K.6
Kalaria, R.N.7
Mann, D.M.8
-
36
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson BI, JE Duda, SM Quinn, B Zhang, JQ Trojanowski and VM Lee (2002) Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 34(4), 521-533.
-
(2002)
Neuron
, vol.34
, Issue.4
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
37
-
-
10744221260
-
Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation
-
Gispert S, D Del Turco, L Garrett, A Chen, DJ Bernard, J Hamm-Clement, HW Korf, T Deller, H Braak, G Auburger and RL Nussbaum (2003) Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation. Mol. Cell. Neurosci. 24 (2), 419-429.
-
(2003)
Mol. Cell. Neurosci.
, vol.24
, Issue.2
, pp. 419-429
-
-
Gispert, S.1
Del Turco, D.2
Garrett, L.3
Chen, A.4
Bernard, D.J.5
Hamm-Clement, J.6
Korf, H.W.7
Deller, T.8
Braak, H.9
Auburger, G.10
Nussbaum, R.L.11
-
38
-
-
0038456964
-
Nuclear localization of alpha-synuclein and its interaction with histones
-
Goers J, AB Manning-Boǧ, AI McCormack, IS Millett, S Donlach, DA Di Monte, VN Uversky and AL Fink (2003) Nuclear localization of alpha-synuclein and its interaction with histones. Biochemistry 42(28), 8465-8471.
-
(2003)
Biochemistry
, vol.42
, Issue.28
, pp. 8465-8471
-
-
Goers, J.1
Manning-Boǧ, A.B.2
McCormack, A.I.3
Millett, I.S.4
Donlach, S.5
Di Monte, D.A.6
Uversky, V.N.7
Fink, A.L.8
-
39
-
-
0141891953
-
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
-
Goldberg MS, SM Fleming, JJ Palacino, C Cepeda, HA Lam, A Bhatnagar, EG Meloni, N Wu, LC Ackerson, GJ Klapstein, M Gajendiran, BL Roth, MF Chesselet, NT Maidment, MS Levine and J Shen (2003) Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J. Biol. Chem. 278 (44), 43628-43635.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.44
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepeda, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
Gajendiran, M.11
Roth, B.L.12
Chesselet, M.F.13
Maidment, N.T.14
Levine, M.S.15
Shen, J.16
-
40
-
-
13844253723
-
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1
-
Goldberg MS, A Pisani, M Haburcak, TA Vortherms, T Kitada, C Costa, Y Tong, G Martella, A Tscherter, A Martins, G Bernardi, BL Roth, EN Pothos, P Calabresi and J Shen (2005) Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron 45 (4), 489-496.
-
(2005)
Neuron
, vol.45
, Issue.4
, pp. 489-496
-
-
Goldberg, M.S.1
Pisani, A.2
Haburcak, M.3
Vortherms, T.A.4
Kitada, T.5
Costa, C.6
Tong, Y.7
Martella, G.8
Tscherter, A.9
Martins, A.10
Bernardi, G.11
Roth, B.L.12
Pothos, E.N.13
Calabresi, P.14
Shen, J.15
-
41
-
-
0037333642
-
Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A3 0P transgenic mice
-
Gomez-Isla T, MC Irizarry, A Mariash, B Cheung, O Soto, S Schrump, J Sondel, L Kotilinek, J Day, MA Schwarzschild, JH Cha, K Newell, DW Miller, K Ueda, AB Young, BT Hyman and KH Ashe (2003) Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A3 0P transgenic mice. Neurobiol. Aging 24, 245-258.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 245-258
-
-
Gomez-Isla, T.1
Irizarry, M.C.2
Soto, A.3
Mariash, B.4
Cheung, O.5
Schrump, S.6
Sondel, J.7
Kotilinek, L.8
Day, J.9
Schwarzschild, M.A.10
Cha, J.H.11
Newell, K.12
Miller, D.W.13
Ueda, K.14
Young, A.B.15
Hyman, B.T.16
Ashe, K.H.17
-
42
-
-
0035693854
-
Is methamphetamine abuse a risk factor in parkinsonism?
-
Guilarte TR (2001) Is methamphetamine abuse a risk factor in parkinsonism? Neurotoxicology 22(6), 725-731.
-
(2001)
Neurotoxicology
, vol.22
, Issue.6
, pp. 725-731
-
-
Guilarte, T.R.1
-
43
-
-
0033814671
-
An autopsy case of autosomal-recessive uvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene
-
Hayashi S, K Wakabayashi, A Ishikawa, H Nagai, M Saito, M Maruyama, T Takahashi, T Ozawa, S Tsuji and H Takahashi (2000) An autopsy case of autosomal-recessive uvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene. Mov. Disord. 15(5), 884-888.
-
(2000)
Mov. Disord.
, vol.15
, Issue.5
, pp. 884-888
-
-
Hayashi, S.1
Wakabayashi, K.2
Ishikawa, A.3
Nagai, H.4
Saito, M.5
Maruyama, M.6
Takahashi, T.7
Ozawa, T.8
Tsuji, S.9
Takahashi, H.10
-
44
-
-
0021280826
-
1984 Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydro-pyridine in mice
-
Heikkila RE, A Hess and RC Duvoisin (1984) Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydro-pyridine in mice. Science 224(4656), 1451-1453.
-
Science
, vol.224
, Issue.4656
, pp. 1451-1453
-
-
Heikkila, R.E.1
Hess, A.2
Duvoisin, R.C.3
-
45
-
-
0037314540
-
Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats
-
Hoglinger GU, J Feger, A Prigent, PP Michel, K Parain, P Champy, M Ruberg, WH Oertel and EC Hirsch (2003) Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats. J. Neurochem. 84(3), 491-502.
-
(2003)
J. Neurochem.
, vol.84
, Issue.3
, pp. 491-502
-
-
Hoglinger, G.U.1
Feger, J.2
Prigent, A.3
Michel, P.P.4
Parain, K.5
Champy, P.6
Ruberg, M.7
Oertel, W.H.8
Hirsch, E.C.9
-
46
-
-
28244445138
-
The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy
-
Hoglinger GU, A Lannuzel, ME Khondiker, PP Michel, C Duyckaerts, J Feger, P Champy, A Prigent, F Medja, A Lombes, WH Oertel, M Ruberg and EC Hirsch (2005) The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy. J. Neurochem. 95(4), 930-939.
-
(2005)
J. Neurochem.
, vol.95
, Issue.4
, pp. 930-939
-
-
Hoglinger, G.U.1
Lannuzel, A.2
Khondiker, M.E.3
Michel, P.P.4
Duyckaerts, C.5
Feger, J.6
Champy, P.7
Prigent, A.8
Medja, F.9
Lombes, A.10
Oertel, W.H.11
Ruberg, M.12
Hirsch, E.C.13
-
47
-
-
10744221310
-
Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
-
Itier JM, P Ibanez, MA Mena, N Abbas, C Cohen-Salmon, GA Bohme, M Laville, J Pratt, O Corti, L Pradier, G Ret, C Joubert, M Periquet, F Araujo, J Negroni, MJ Casarejos, S Canals, R Solano, A Serrano, E Gallego, M Sanchez, P Denefle, J Benavides, G Tremp, TA Rooney, A Brice and J Garcia de Yebenes (2003) Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum. Mol. Genet. 12(18), 2277-2291.
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.18
, pp. 2277-2291
-
-
Itier, J.M.1
Ibanez, P.2
Abbas, M.A.3
Mena, N.4
Cohen-Salmon, C.5
Bohme, G.A.6
Laville, M.7
Pratt, J.8
Corti, O.9
Pradier, L.10
Ret, G.11
Joubert, C.12
Periquet, M.13
Araujo, F.14
Negroni, J.15
Casarejos, M.J.16
Canals, S.17
Solano, R.18
Serrano, A.19
Gallego, E.20
Sanchez, M.21
Denefle, P.22
Benavides, J.23
Tremp, G.24
Rooney, T.A.25
Brice, A.26
Garcia de Yebenes, J.27
more..
-
48
-
-
0000340348
-
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine, uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
-
Javitch JA, RJ D'Amato, SM Strittmatter and SH Snyder (1985) Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine, uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc. Natl. Acad. Sci. USA 82(7), 2173-7.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, Issue.7
, pp. 2173-2177
-
-
Javitch, J.A.1
D'Amato, R.J.2
Strittmatter, S.M.3
Snyder, S.H.4
-
49
-
-
0034527763
-
Physiology and pathophysiology of alpha-synuclein. Cell culture and transgenic animal models based on a Parkinson's disease-associated protein
-
Kahle PJ, M Neumann, L Ozmen and C Haass (2000a) Physiology and pathophysiology of alpha-synuclein. Cell culture and transgenic animal models based on a Parkinson's disease-associated protein. Ann. NY Acad. Sci. 920, 33-41.
-
(2000)
Ann. NY Acad. Sci.
, vol.920
, pp. 33-41
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
Haass, C.4
-
50
-
-
0034280435
-
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain
-
Kahle PJ, M Neumann, L Ozmen, V Muller, H Jacobsen, A Schindzielorz, M Okochi, U Leimer, H van Der Putten, A Probst, E Kremmer, HA Kretzschmar and C Haass (2000b) Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain. J. Neurosci. 20(17), 6365-6373.
-
(2000)
J. Neurosci.
, vol.20
, Issue.17
, pp. 6365-6373
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
Muller, V.4
Jacobsen, H.5
Schindzielorz, A.6
Okochi, M.7
Leimer, U.8
van Der Putten, H.9
Probst, A.10
Kremmer, E.11
Kretzschmar, H.A.12
Haass, C.13
-
51
-
-
0242684415
-
Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: A novel therapy for Parkinson's disease
-
Kaur D, F Yantiri, S Rajagopalan, J Kumar, JQ Mo, R Boonplueang. V Viswanath, R Jacobs, L Yang, MF Beal, D DiMonte, I Volitaskis, L Ellerby, RA Cherny, AI Bush and JK Andersen (2003) Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: A novel therapy for Parkinson's disease. Neuron 37(6), 899-909.
-
(2003)
Neuron
, vol.37
, Issue.6
, pp. 899-909
-
-
Kaur, D.1
Yantiri, F.2
Rajagopalan, S.3
Kumar, J.4
Mo, J.Q.5
Boonplueang, R.6
Viswanath, V.7
Jacobs, R.8
Yang, L.9
Beal, M.F.10
DiMonte, D.11
Volitaskis, I.12
Ellerby, L.13
Cherny, R.A.14
Bush, A.I.15
Andersen, J.K.16
-
52
-
-
0032707654
-
Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury
-
Kholodilov NG, M Neystat, TF Oo, SE Lo, KE Larsen, D Sulzer and RE Burke (1999) Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury. J. Neurochem. 73(6), 2586-2599.
-
(1999)
J. Neurochem.
, vol.73
, Issue.6
, pp. 2586-2599
-
-
Kholodilov, N.G.1
Neystat, M.2
Oo, T.F.3
Lo, S.E.4
Larsen, K.E.5
Sulzer, D.6
Burke, R.E.7
-
53
-
-
0032717232
-
Synuclein expression is decreased in rat substantia nigra following induction of apoptosis by intrastriatal 6-hydroxydopamine
-
Kholodilov NG, TF Oo and RE Burke (1999) Synuclein expression is decreased in rat substantia nigra following induction of apoptosis by intrastriatal 6-hydroxydopamine. Neurosci. Lett. 275(2), 105-108.
-
(1999)
Neurosci. Lett.
, vol.275
, Issue.2
, pp. 105-108
-
-
Kholodilov, N.G.1
Oo, T.F.2
Burke, R.E.3
-
54
-
-
20244365801
-
DJ-1, a novel regulator of the tumor suppressor PTEN
-
Kim RH, M Peters, Y Jang, W Shi, M Pintillie, GC Fletcher, C DeLuca, J Liepa, L Zhou, B Snow, RC Binari, AS Manoukian, MR Bray, FF Liu, MS Tsao and TW Mak (2005) DJ-1, a novel regulator of the tumor suppressor PTEN. Cancer Cell 7(3), 263-273.
-
(2005)
Cancer Cell
, vol.7
, Issue.3
, pp. 263-273
-
-
Kim, R.H.1
Peters, M.2
Jang, Y.3
Shi, W.4
Pintillie, M.5
Fletcher, G.C.6
DeLuca, C.7
Liepa, J.8
Zhou, L.9
Snow, B.10
Binari, R.C.11
Manoukian, A.S.12
Bray, M.R.13
Liu, F.F.14
Tsao, M.S.15
Mak, T.W.16
-
55
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
-
Kim RH, PD Smith, H Aleyasin, S Hayley, MP Mount, S Pownall, A Wakeham, AJ You-Ten, SK Kalia, P Horne, D Westaway, AM Lozano, H Anisman, DS Park and TW Mak (2005) Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc. Natl. Acad. Sci. USA 102(14), 5215-5220.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.14
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
Pownall, S.6
Wakeham, A.7
You-Ten, A.J.8
Kalia, S.K.9
Horne, P.10
Westaway, D.11
Lozano, A.M.12
Anisman, H.13
Park, D.S.14
Mak, T.W.15
-
56
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno and N Shimizu (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392(6676), 605-608.
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
57
-
-
33244460534
-
Mice lacking alpha-synuclein are resistant to mitochondrial toxins
-
Klivenyi P, D Siwek, G Gardian, L Yang, A Taarkov, C Cleren, RJ Ferrante, NW Kowall, A Abellovich and MF Beal (2006) Mice lacking alpha-synuclein are resistant to mitochondrial toxins. Neurobiol Dis. 21(3), 541-548.
-
(2006)
Neurobiol Dis.
, vol.21
, Issue.3
, pp. 541-548
-
-
Klivenyi, P.1
Siwek, D.2
Gardian, G.3
Yang, L.4
Taarkov, A.5
Cleren, C.6
Ferrante, R.J.7
Kowall, N.W.8
Abellovich, A.9
Beal, M.F.10
-
58
-
-
33749583553
-
α-Synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
-
Kontopoulos E., JD Parvin and MB Feany (2006) α-Synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Hum. Mol. Genet. 15 (20), 3012-3023.
-
(2006)
Hum. Mol. Genet.
, vol.15
, Issue.20
, pp. 3012-3023
-
-
Kontopoulos, E.1
Parvin, J.D.2
Feany, M.B.3
-
59
-
-
33750357866
-
Proposed animal model of severe Parkinson's disease, neonatal 6-hydroxydopamine lesion of dopaminergic innervation of striatum
-
Kostrzewa RM, JP Kostrzewa, R Brus, RA Kostrzewa and P Nowak (2006) Proposed animal model of severe Parkinson's disease, neonatal 6-hydroxydopamine lesion of dopaminergic innervation of striatum. J. Neural Transm. Suppl. 70, 277-279.
-
(2006)
J. Neural Transm. Suppl.
, vol.70
, pp. 277-279
-
-
Kostrzewa, R.M.1
Kostrzewa, J.P.2
Brus, R.3
Kostrzewa, R.A.4
Nowak, P.5
-
60
-
-
0034676997
-
MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons
-
Kowall NW, P Hantraye, E Brouillet, MF Beal, AC McKee and RJ Ferrante (2000) MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons. Neuroreport 11(1), 211-213.
-
(2000)
Neuroreport
, vol.11
, Issue.1
, pp. 211-213
-
-
Kowall, N.W.1
Hantraye, P.2
Brouillet, E.3
Beal, M.F.4
McKee, A.C.5
Ferrante, R.J.6
-
61
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R, W Kuhn, T Muller, D Woitalla, M Graeber, S Kosel, H Przuntek, JT Epplen, L Schols and O Riess (1998) Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet. 18(2), 106-108.
-
(1998)
Nat. Genet.
, vol.18
, Issue.2
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
62
-
-
0030864433
-
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice
-
Lan J and DH Jiang (1997) Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice. J. Neural Transm. 104(4-5), 469-481.
-
(1997)
J. Neural Transm.
, vol.104
, Issue.4-5
, pp. 469-481
-
-
Lan, J.1
Jiang, D.H.2
-
63
-
-
33645755812
-
The Parkinson's complex, parkinsonism is just the tip of the iceberg
-
Langston JW (2006) The Parkinson's complex, parkinsonism is just the tip of the iceberg. Ann. Neurol. 59(4), 591-6.
-
(2006)
Ann. Neurol.
, vol.59
, Issue.4
, pp. 591-596
-
-
Langston, J.W.1
-
64
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston JW, P Ballard, JW Tetrud and I Irwin (1983) Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219(4587), 979-980.
-
(1983)
Science
, vol.219
, Issue.4587
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
65
-
-
0021337873
-
Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey
-
Langston JW, LS Forno, CS Rebert and I Irwin (1984) Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey. Brain Res. 292(2), 390-394.
-
(1984)
Brain Res.
, vol.292
, Issue.2
, pp. 390-394
-
-
Langston, J.W.1
Forno, L.S.2
Rebert, C.S.3
Irwin, I.4
-
66
-
-
3042827092
-
Rotenone induces non-specific central nervous system and systemic toxicity
-
Lapointe N, M St-Hilaire, MG Martinoli, J Blanchet J Blanchet, P Gould, C Rouillard and F Cicchetti (2004) Rotenone induces non-specific central nervous system and systemic toxicity. FASEB J. 18(6), 717-719.
-
(2004)
FASEB J.
, vol.18
, Issue.6
, pp. 717-719
-
-
Lapointe, N.1
St-Hilaire, M.2
Martinoli, M.G.3
Blanchet, J.4
Blanchet, J.5
Gould, P.6
Rouillard, C.7
Cicchetti, F.8
-
67
-
-
0037173006
-
Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 -> Thr mutation causes neuro-degenerative disease with alpha-synuclein aggregation in transgenic mice
-
Lee MK, W Stirling, Y Xu, X Xu, D Qui, AS Mandir, TM Dawson, NG Copeland, NA Jenkins and DL Price (2002) Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 -> Thr mutation causes neuro-degenerative disease with alpha-synuclein aggregation in transgenic mice. Proc. Natl. Acad. Sci. USA 99(13), 8968-8973.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.13
, pp. 8968-8973
-
-
Lee, M.K.1
Stirling, W.2
Xu, Y.3
Xu, X.4
Qui, D.5
Mandir, A.S.6
Dawson, T.M.7
Copeland, N.G.8
Jenkins, N.A.9
Price, D.L.10
-
68
-
-
1342323484
-
Combined toxicity of prenatal bacterial endotoxin exposure and postnatal 6-hydroxydopamine in the adult rat midbrain
-
Ling ZD, Q Chang, JW Lipton, CW Tong, TM Landers and PM Carvey (2004) Combined toxicity of prenatal bacterial endotoxin exposure and postnatal 6-hydroxydopamine in the adult rat midbrain. Neuroscience 124(3), 619-628.
-
(2004)
Neuroscience
, vol.124
, Issue.3
, pp. 619-628
-
-
Ling, Z.D.1
Chang, Q.2
Lipton, J.W.3
Tong, C.W.4
Landers, T.M.5
Carvey, P.M.6
-
69
-
-
33745243255
-
Progressive dopamine neuron loss following supra-nigral lipopolysaccharide (LPS) infusion into rats exposed to LPS prenatally
-
Ling Z, Y Zhu, C Tong, JA Snyder, JW Lipton and PM Carvey (2006) Progressive dopamine neuron loss following supra-nigral lipopolysaccharide (LPS) infusion into rats exposed to LPS prenatally. Exp Neurol. 199(2), 499-512.
-
(2006)
Exp Neurol
, vol.199
, Issue.2
, pp. 499-512
-
-
Ling, Z.1
Zhu, Y.2
Tong, C.3
Snyder, J.A.4
Lipton, J.W.5
Carvey, P.M.6
-
70
-
-
0030878320
-
Environmental risk factors and Parkinson's disease, a case-control study in Taiwan
-
Liou HH, MC Tsai, CJ Chen, JS Jeng, YC Chang, SY Chen and RC Chen (1997) Environmental risk factors and Parkinson's disease, a case-control study in Taiwan. Neurology 48(6), 1583-1588.
-
(1997)
Neurology
, vol.48
, Issue.6
, pp. 1583-1588
-
-
Liou, H.H.1
Tsai, M.C.2
Chen, C.J.3
Jeng, J.S.4
Chang, Y.C.5
Chen, S.Y.6
Chen, R.C.7
-
71
-
-
1842441089
-
It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG)
-
Lockhart PJ, CA O'Farrell and MJ Farrer (2004) It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG). Mov. Disord. 19(1), 101-104.
-
(2004)
Mov. Disord.
, vol.19
, Issue.1
, pp. 101-104
-
-
Lockhart, P.J.1
O'Farrell, C.A.2
Farrer, M.J.3
-
72
-
-
0037127197
-
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice, paraquat and α-synuclein
-
Manning-Boǧn AB, AL McCormack, J Li, VN Uversky, AL Fink and DA Di Monte (2002) The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice, paraquat and α-synuclein. J. Biol. Chem. 277, 1641-1644.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1641-1644
-
-
Manning-Boǧn, A.B.1
McCormack, A.L.2
Li, J.3
Uversky, V.N.4
Fink, A.L.5
Di Monte, D.A.6
-
73
-
-
0038334899
-
α-Synuclein over-expression protects against paraquat-induced neurodegeneration
-
Manning-Boǧ AB, AL McCormack, MG Purisai, LM Bolin and DA Di Monte (2003) α-Synuclein over-expression protects against paraquat-induced neurodegeneration. J. Neurosci. 23(8), 3095-3099.
-
(2003)
J. Neurosci.
, vol.23
, Issue.8
, pp. 3095-3099
-
-
Manning-Boǧ, A.B.1
McCormack, A.L.2
Purisai, M.G.3
Bolin, L.M.4
Di Monte, D.A.5
-
74
-
-
30644471051
-
Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
Martin LJ, Y Pan, AC Price, W Sterling, NG Copeland, NA Jenkins, DL Price and MK Lee (2006) Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J. Neurosci. 26(1), 41-50.
-
(2006)
J. Neurosci.
, vol.26
, Issue.1
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
Price, D.L.7
Lee, M.K.8
-
75
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in alpha-synuclein mice, implications for neurodegenerative disorders
-
Masliah E, E Rockenstein, I Veinbergs, M Mallory, M Hashimoto, A Takeda, Y Sagara, A Sisk and L Mucke (2000) Dopaminergic loss and inclusion body formation in alpha-synuclein mice, implications for neurodegenerative disorders. Science 287(5456), 1265-1269.
-
(2000)
Science
, vol.287
, Issue.5456
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
76
-
-
0034979314
-
Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter
-
Matsuoka Y, M Vila, S Lincoln, A McCormack, M Picciano, J LaFrancois, X Yu, D Dickson, JW Langston, E McGowan, M Farrer, J Hardy, K Duff, S Przedborski and DA Di Monte (2001) Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter. Neurobiol. Dis. 8(3), 535-539.
-
(2001)
Neurobiol. Dis.
, vol.8
, Issue.8
, pp. 535-539
-
-
Matsuoka, Y.1
Vila, M.2
Lincoln, S.3
McCormack, A.4
Picciano, M.5
LaFrancois, J.6
Yu, X.7
Dickson, D.8
Langston, J.W.9
McGowan, E.10
Farrer, M.11
Hardy, J.12
Duff, K.13
Przedborski, S.14
Di Monte, D.A.15
-
77
-
-
33749548502
-
Over-expression of alpha-synuclein following methamphetamine, is it good or bad?
-
Mauceli G, CI Busceti, A Pellegrini, P Soldani, P Lenzi, A Paparelli and F Fornai (2006) Over-expression of alpha-synuclein following methamphetamine, is it good or bad? Ann. NY Acad. Sci. 1074, 191-197.
-
(2006)
Ann. NY Acad. Sci.
, vol.1074
, pp. 191-197
-
-
Mauceli, G.1
Busceti, C.I.2
Pellegrini, A.3
Soldani, P.4
Lenzi, P.5
Paparelli, A.6
Fornai, F.7
-
78
-
-
0037380982
-
Effects of L-dopa and other amino acids against paraquat-induced nigros-triatal degeneration
-
McCormack AL and DA Di Monte (2003) Effects of L-dopa and other amino acids against paraquat-induced nigros-triatal degeneration. J. Neurochem. 85(1), 82-86.
-
(2003)
J. Neurochem.
, vol.85
, Issue.1
, pp. 82-86
-
-
McCormack, A.L.1
Di Monte, D.A.2
-
79
-
-
0036075892
-
Environmental risk factors and Parkinson's disease, selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
-
McCormack AL, M Thiruchelvam, AB Manning-Boǧ, C Thiffault, JW Langston, DA Cory-Slechta and DA Di Monte (2002) Environmental risk factors and Parkinson's disease, selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiol. Dis. 10(2), 119-127.
-
(2002)
Neurobiol. Dis.
, vol.10
, Issue.2
, pp. 119-127
-
-
McCormack, A.L.1
Thiruchelvam, M.2
Manning-Boǧ, A.B.3
Thiffault, C.4
Langston, J.W.5
Cory-Slechta, D.A.6
Di Monte, D.A.7
-
80
-
-
0033030440
-
Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease
-
Miller GW, JD Erickson, JT Perez, SN Penland, DC Mash, DB Rye and AI Levey (1999) Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease. Exp. Neurol. 156(1), 138-148.
-
(1999)
Exp. Neurol.
, vol.156
, Issue.1
, pp. 138-148
-
-
Miller, G.W.1
Erickson, J.D.2
Perez, J.T.3
Penland, S.N.4
Mash, D.C.5
Rye, D.B.6
Levey, A.I.7
-
81
-
-
0028266425
-
Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahy-dropyridine (MPTP)-induced hemiparkinsonian monkeys
-
Mochizuki H, H Imai, K Endo, K Yokomizo, Y Murata, N Hattori and Y Mizuno (1994) Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahy-dropyridine (MPTP)-induced hemiparkinsonian monkeys. Neurosci. Lett. 168, 251-253.
-
(1994)
Neurosci. Lett.
, vol.168
, pp. 251-253
-
-
Mochizuki, H.1
Imai, H.2
Endo, K.3
Yokomizo, K.4
Murata, Y.5
Hattori, N.6
Mizuno, Y.7
-
82
-
-
0346434141
-
A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization
-
Moore DJ, L Zhang, TM Dawson and VL Dawson (2003) A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization. J. Neurochem. 87(6), 1558-1567.
-
(2003)
J. Neurochem.
, vol.87
, Issue.6
, pp. 1558-1567
-
-
Moore, D.J.1
Zhang, L.2
Dawson, T.M.3
Dawson, V.L.4
-
83
-
-
0031566231
-
DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras
-
Nagakubo D, T Taira, H Kitaura, M Ikeda, K Tamai, SM Iguchi-Ariga and H Ariga (1997) DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem. Biophys. Res. Commun. 231(2), 509-513.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.231
, Issue.2
, pp. 509-513
-
-
Nagakubo, D.1
Taira, T.2
Kitaura, H.3
Ikeda, M.4
Tamai, K.5
Iguchi-Ariga, S.M.6
Ariga, H.7
-
84
-
-
0036855635
-
Misfolded proteinase K-resistant hyperphos-phorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucle-inopathies
-
Neumann M, PJ Kahle, BI Giasson, L Ozmen, E Borroni, W Spooren, V Muller, S Odoy, H Fujiwara, M Hasegawa, T Iwatsubo, JQ Trojanowski, HA Kretzschmar and C Haass (2002) Misfolded proteinase K-resistant hyperphos-phorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucle-inopathies. J. Clin. Invest. 110(10), 1429-1439.
-
(2002)
J. Clin. Invest.
, vol.110
, Issue.10
, pp. 1429-1439
-
-
Neumann, M.1
Kahle, P.J.2
Giasson, B.I.3
Ozmen, L.4
Borroni, E.5
Spooren, W.6
Muller, V.7
Odoy, S.8
Fujiwara, H.9
Hasegawa, M.10
Iwatsubo, T.11
Trojanowski, J.Q.12
Kretzschmar, H.A.13
Haass, C.14
-
85
-
-
0021810979
-
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
-
Nicklas WJ, I Vyas and RE Heikkila (1985) Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci. 36(26), 2503-2508.
-
(1985)
Life Sci.
, vol.36
, Issue.26
, pp. 2503-2508
-
-
Nicklas, W.J.1
Vyas, I.2
Heikkila, R.E.3
-
86
-
-
33646476833
-
Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice
-
Nieto M, FJ Gil-Bea, E Dalfo, M Guadrado, F Cabodevilla, B Sanchez, S Catena, T Sesma, E Ribe, I Ferrer, MJ Ramirez and T Gomez-Isla (2006) Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice. Neurobiol. Aging 27(6), 848-856.
-
(2006)
Neurobiol. Aging
, vol.27
, Issue.6
, pp. 848-856
-
-
Nieto, M.1
Gil-Bea, F.J.2
Dalfo, E.3
Guadrado, M.4
Cabodevilla, F.5
Sanchez, B.6
Catena, S.7
Sesma, T.8
Ribe, E.9
Ferrer, I.10
Ramirez, M.J.11
Gomez-Isla, T.12
-
87
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
-
Paisan-Ruiz C, S Jain, EW Evans, WP Gilks, J Simon, M van der Brug, A Lopez de Munain, S Aparicio, AM Gil, N Khan, J Johnson, JR Martinez, D Nicholl, IM Carrera, AS Pena, R de Silva, A Lees, JF Marti-Masso, J Perez-Tur, NW Wood and AB Singleton (2004) Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 44(4), 595-600.
-
(2004)
Neuron
, vol.44
, Issue.4
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
Gilks, W.P.4
Simon, J.5
van der Brug, M.6
Lopez de Munain, A.7
Aparicio, S.8
Gil, A.M.9
Khan, N.10
Johnson, J.11
Martinez, J.R.12
Nicholl, D.13
Carrera, I.M.14
Pena, A.S.15
de Silva, R.16
Lees, A.17
Marti-Masso, J.F.18
Perez-Tur, J.19
Wood, N.W.20
Singleton, A.B.21
more..
-
88
-
-
2442481789
-
Mitochondrial dys-function and oxidative damage in parkin-deficient mice
-
Palacino JJ, D Sagi, MS Goldberg, S Krauss, C Motz, M Wacker, J Klose and J Shen (2004) Mitochondrial dys-function and oxidative damage in parkin-deficient mice. J. Biol. Chem. 279(18), 18614-18622.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.18
, pp. 18614-18622
-
-
Palacino, J.J.1
Sagi, D.2
Goldberg, M.S.3
Krauss, S.4
Motz, C.5
Wacker, M.6
Klose, J.7
Shen, J.8
-
89
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
Parker WD Jr, S J Boyson and JK Parks (1989) Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann. Neurol. 26(6), 719-723.
-
(1989)
Ann. Neurol.
, vol.26
, Issue.6
, pp. 719-723
-
-
Parker Jr., W.D.1
Boyson, S.J.2
Parks, J.K.3
-
90
-
-
3543011314
-
The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway
-
Epub 2004 May 20
-
Peng J, XO Mao, FF Stevenson, M Hsu and JK Andersen (2004) The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway. J. Biol. Chem. 279 (31), 32626-32632. Epub 2004 May 20.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.31
, pp. 32626-32632
-
-
Peng, J.1
Mao, X.O.2
Stevenson, F.F.3
Hsu, M.4
Andersen, J.K.5
-
91
-
-
13844313915
-
Parkin-deficient mice are not a robust model of parkinsonism
-
Perez FA and RD Palmiter (2005) Parkin-deficient mice are not a robust model of parkinsonism. Proc. Natl. Acad. Sci. USA 102(6), 2174-2179.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.6
, pp. 2174-2179
-
-
Perez, F.A.1
Palmiter, R.D.2
-
92
-
-
30344450813
-
Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity
-
Perez FA, WR Curtis and RD Palmiter (2005) Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity. BMC Neurosci. 6, 71.
-
(2005)
BMC Neurosci.
, vol.6
, pp. 71
-
-
Perez, F.A.1
Curtis, W.R.2
Palmiter, R.D.3
-
93
-
-
0022445973
-
Paraquat and two endogenous analogues of the neurotoxic substance N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine do not damage dopaminergic nigrostriatal neurons in the mouse
-
Perry TL, VW Yong, RA Wall and K Jones (1986) Paraquat and two endogenous analogues of the neurotoxic substance N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine do not damage dopaminergic nigrostriatal neurons in the mouse. Neurosci. Lett. 69(3), 285-289.
-
(1986)
Neurosci. Lett.
, vol.69
, Issue.3
, pp. 285-289
-
-
Perry, T.L.1
Yong, V.W.2
Wall, R.A.3
Jones, K.4
-
94
-
-
0035960066
-
Mouse model of Parkinsonism, a comparison between subacute MPTP and chronic MPTP/probenecid treatment
-
Petroske E, GE Meredith, S Callen, S Totterdell and YS Lau (2001) Mouse model of Parkinsonism, a comparison between subacute MPTP and chronic MPTP/probenecid treatment. Neuroscience 106(3), 589-601.
-
(2001)
Neuroscience
, vol.106
, Issue.3
, pp. 589-601
-
-
Petroske, E.1
Meredith, G.E.2
Callen, S.3
Totterdell, S.4
Lau, Y.S.5
-
95
-
-
0030790785
-
Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine, a possible contributory mechanism for neuronal degeneration in Parkinson's disease
-
Pezzella A, M d'Ischia, A Napolitano, G Misuraca and G Prota (1997) Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine, a possible contributory mechanism for neuronal degeneration in Parkinson's disease. J. Med. Chem. 40(14), 2211-2216.
-
(1997)
J. Med. Chem.
, vol.40
, Issue.14
, pp. 2211-2216
-
-
Pezzella, A.1
d'Ischia, M.2
Napolitano, A.3
Misuraca, G.4
Prota, G.5
-
96
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, C Lavedan, E Leroy, SE Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer, ES Stenroos, S Chandrasekharappa, A Athanassiadou, T Papapetropoulos, WG Johnson, AM Lazzarini, RC Duvoisin, G Di Iorio, LI Golbe and RL Nussbaum (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276(5321), 2045-2047.
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
97
-
-
24644462201
-
Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers
-
Pramstaller PP, MG Schlossmacher, TS Jacques, F Scaravilli, C Eskelson, I Pepivani, K Hedrich, S Adel, M Gonzales-McNeal, R Hilker, PL Kramer and C Klein (2005) Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers. Ann. Neurol. 58(3), 411-422.
-
(2005)
Ann. Neurol.
, vol.58
, Issue.3
, pp. 411-422
-
-
Pramstaller, P.P.1
Schlossmacher, M.G.2
Jacques, T.S.3
Scaravilli, F.4
Eskelson, C.5
Pepivani, I.6
Hedrich, K.7
Adel, S.8
Gonzales-McNeal, M.9
Hilker, R.10
Kramer, P.L.11
Klein, C.12
-
98
-
-
33846308531
-
Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration
-
Purisai MG, AL McCormack, S Cumine, J Li, MZ Isla and DA Di Monte (2007) Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration. Neurobiol. Dis. 25(2), 392-400.
-
(2007)
Neurobiol. Dis.
, vol.25
, Issue.2
, pp. 392-400
-
-
Purisai, M.G.1
McCormack, A.L.2
Cumine, S.3
Li, J.4
Isla, M.Z.5
Di Monte, D.A.6
-
99
-
-
27744450270
-
Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates
-
Purisai MG, AL McCormack, JW Langston, LC Johnston and DA Di Monte (2005) Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates. Neurobiol. Dis. 20(3), 898-906.
-
(2005)
Neurobiol. Dis.
, vol.20
, Issue.3
, pp. 898-906
-
-
Purisai, M.G.1
McCormack, A.L.2
Langston, J.W.3
Johnston, L.C.4
Di Monte, D.A.5
-
100
-
-
33847759064
-
Systemic LPS causes chronic neuroinflammation and progressive neurodegen-eration
-
Qin L, X Wu, ML Block, Y Liu, GR Breese, JS Hong, DJ Knapp and FT Crews (2007) Systemic LPS causes chronic neuroinflammation and progressive neurodegen-eration. Glia 55(5), 453-462.
-
(2007)
Glia
, vol.55
, Issue.5
, pp. 453-462
-
-
Qin, L.1
Wu, X.2
Block, M.L.3
Liu, Y.4
Breese, G.R.5
Hong, J.S.6
Knapp, D.J.7
Crews, F.T.8
-
101
-
-
33750308194
-
Parkinsonism, Lrrk2 G'S, and tau neuropa-thology
-
Rajput A, DW Dickson, CA Robinson, OA Ross, JC Dachsel, SJ Lincoln, SA Cobb, ML Rajput and MJ Farrer (2006) Parkinsonism, Lrrk2 G'S, and tau neuropa-thology. Neurology 67(8), 1506-1508.
-
(2006)
Neurology
, vol.67
, Issue.8
, pp. 1506-1508
-
-
Rajput, A.1
Dickson, D.W.2
Robinson, C.A.3
Ross, O.A.4
Dachsel, J.C.5
Lincoln, S.J.6
Cobb, S.A.7
Rajput, M.L.8
Farrer, M.J.9
-
102
-
-
0023001744
-
Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria
-
Ramsay RR and TP Singer (1986) Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria. J. Biol. Chem. 261(17), 7585-7587.
-
(1986)
J. Biol. Chem.
, vol.261
, Issue.17
, pp. 7585-7587
-
-
Ramsay, R.R.1
Singer, T.P.2
-
103
-
-
0035659556
-
The aetiology of idiopathic Parkinson's disease
-
Ramsden DB, RB Parsons, SL Ho and RH Waring (2001) The aetiology of idiopathic Parkinson's disease. Mol. Pathol. 54(6), 369-380.
-
(2001)
Mol. Pathol.
, vol.54
, Issue.6
, pp. 369-380
-
-
Ramsden, D.B.1
Parsons, R.B.2
Ho, S.L.3
Waring, R.H.4
-
104
-
-
0035017068
-
Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice
-
Rathke-Hartlieb S, PJ Kahle, M Neumann, L Ozmen, S Haid, M Okochi, C Haas and JB Schulz (2001) Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice. J. Neurochem. 77(4), 1181-1184.
-
(2001)
J. Neurochem.
, vol.77
, Issue.4
, pp. 1181-1184
-
-
Rathke-Hartlieb, S.1
Kahle, P.J.2
Neumann, M.3
Ozmen, L.4
Haid, S.5
Okochi, M.6
Haas, C.7
Schulz, J.B.8
-
105
-
-
33845642692
-
Obligatory role for complex I inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
-
Richardson JR, WM Caudle, TS Guillot, JL Watson, E Nakamaru-Ogiso, BB Seo, TB Sherer, JT Greenamyre, T Yagi, A Matsuno-Yagi and GW Miller (2007) Obligatory role for complex I inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Toxicol. Sci. 95(1), 196-204.
-
(2007)
Toxicol. Sci.
, vol.95
, Issue.1
, pp. 196-204
-
-
Richardson, J.R.1
Caudle, W.M.2
Guillot, T.S.3
Watson, J.L.4
Nakamaru-Ogiso, E.5
Seo, B.B.6
Sherer, T.B.7
Greenamyre, J.T.8
Yagi, T.9
Matsuno-Yagi, A.10
Miller, G.W.11
-
106
-
-
27644459974
-
Paraquat neurotoxicity is distinct from that of MPTP and rotenone
-
Richardson JR, Y Quan, TB Sherer, JT Greenamyre and GW Miller (2005) Paraquat neurotoxicity is distinct from that of MPTP and rotenone. Toxicol. Sci. 88(1), 193-201.
-
(2005)
Toxicol. Sci.
, vol.88
, Issue.1
, pp. 193-201
-
-
Richardson, J.R.1
Quan, Y.2
Sherer, T.B.3
Greenamyre, J.T.4
Miller, G.W.5
-
107
-
-
0036245056
-
Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice
-
Richfield EK, MJ Thiruchelvam, DA Cory-Slechta, C Wuertzer, RR Gainetdinov, MG Caron, DA Di Monte and HJ Federoff (2002) Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice. Exp. Neurol. 175(1), 35-48.
-
(2002)
Exp. Neurol.
, vol.175
, Issue.1
, pp. 35-48
-
-
Richfield, E.K.1
Thiruchelvam, M.J.2
Cory-Slechta, D.A.3
Wuertzer, C.4
Gainetdinov, R.R.5
Caron, M.G.6
Di Monte, D.A.7
Federoff, H.J.8
-
108
-
-
33847274641
-
Chronic rotenone treatment induces behavioral effects but no pathological signs of parkinsonism in mice
-
Richter F, M Hamann and A Richter (2007) Chronic rotenone treatment induces behavioral effects but no pathological signs of parkinsonism in mice. J. Neurosci. Res. 85(3), 681-691.
-
(2007)
J. Neurosci. Res.
, vol.85
, Issue.3
, pp. 681-691
-
-
Richter, F.1
Hamann, M.2
Richter, A.3
-
109
-
-
33750299699
-
Genetic causes of Parkinson's disease, extending the pathway
-
Riess O, R Kruger, H Hochstrasser, AS Soehn, S Nuber, T Franck and D Berg (2006) Genetic causes of Parkinson's disease, extending the pathway. J. Neural Transm. Suppl. 70, 181-189.
-
(2006)
J. Neural Transm. Suppl.
, vol.70
, pp. 181-189
-
-
Riess, O.1
Kruger, R.2
Hochstrasser, H.3
Soehn, A.S.4
Nuber, S.5
Franck, T.6
Berg, D.7
-
110
-
-
0036605566
-
Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters
-
Rockenstein E, M Mallory, M Hashimoto, D Song, CW Shults, I Lang and E Masliah (2002) Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters. J. Neurosci. Res. 68(5), 568-578.
-
(2002)
J. Neurosci. Res.
, vol.68
, Issue.5
, pp. 568-578
-
-
Rockenstein, E.1
Mallory, M.2
Hashimoto, M.3
Song, D.4
Shults, C.W.5
Lang, I.6
Masliah, E.7
-
112
-
-
4143125488
-
Parkin-positive autosomal recessive juvenile Parkinsonism with alpha-synuclein-positive inclusions
-
Sasaki S, A Shirata, K Yamane and M Iwata (2004) Parkin-positive autosomal recessive juvenile Parkinsonism with alpha-synuclein-positive inclusions. Neurology 63(4), 678-82.
-
(2004)
Neurology
, vol.63
, Issue.4
, pp. 678-682
-
-
Sasaki, S.1
Shirata, A.2
Yamane, K.3
Iwata, M.4
-
113
-
-
0028274216
-
Evidence for mitochondrial dysfunction in Parkinson's disease - A critical appraisal
-
Schapira AH (1994) Evidence for mitochondrial dysfunction in Parkinson's disease - a critical appraisal. Mov. Disord. 9, 125-138.
-
(1994)
Mov. Disord.
, vol.9
, pp. 125-138
-
-
Schapira, A.H.1
-
114
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira AH, JM Cooper, D Dexter, JB Clark, P Jenner and CD Marsden (1990) Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 54(3), 823-827.
-
(1990)
J. Neurochem.
, vol.54
, Issue.3
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
115
-
-
0038404962
-
Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyri-dine-induced parkinsonism in mice
-
Schluter OM, F Fornai, MG Alessandri, S Takamori, M Geppert, R Jahn and TC Sudhof (2003) Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyri-dine-induced parkinsonism in mice. Neuroscience 118, 985-1002.
-
(2003)
Neuroscience
, vol.118
, pp. 985-1002
-
-
Schluter, O.M.1
Fornai, F.2
Alessandri, M.G.3
Takamori, S.4
Geppert, M.5
Jahn, R.6
Sudhof, T.C.7
-
116
-
-
0026526723
-
Acute and persistent parkinsonism after use of diquat
-
Sechi GP, V Agnetti, M Piredda, M Canu, F Deserra, HA Omar and G Rosati. (1992) Acute and persistent parkinsonism after use of diquat. Neurology 42(1), 261-263.
-
(1992)
Neurology
, vol.42
, Issue.1
, pp. 261-263
-
-
Sechi, G.P.1
Agnetti, V.2
Piredda, M.3
Canu, M.4
Deserra, F.5
Omar, H.A.6
Rosati, G.7
-
117
-
-
15844397278
-
Neurotoxins and neurotoxic species implicated in neurodegeneration
-
Segura Aguilar J and RM Kostrzewa (2004) Neurotoxins and neurotoxic species implicated in neurodegeneration. Neurotox. Res. 6(7-8), 615-630.
-
(2004)
Neurotox. Res.
, vol.6
, Issue.7-8
, pp. 615-630
-
-
Segura Aguilar, J.1
Kostrzewa, R.M.2
-
118
-
-
4444266341
-
Localization of DJ-1 mRNA in the mouse brain
-
Shang H, D Lang, B Jean-Marc and A Kaelin-Lang (2004) Localization of DJ-1 mRNA in the mouse brain. Neurosci. Lett. 367(3), 273-277.
-
(2004)
Neurosci. Lett.
, vol.367
, Issue.3
, pp. 273-277
-
-
Shang, H.1
Lang, D.2
Jean-Marc, B.3
Kaelin-Lang, A.4
-
119
-
-
13944267769
-
DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation
-
Shendelman S, A Jonason, C Martinat, T Leete and A Abeliovich (2004) DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation. PLoS Biol. 2(11), e362.
-
(2004)
PLoS Biol.
, vol.2
, Issue.11
-
-
Shendelman, S.1
Jonason, A.2
Martinat, C.3
Leete, T.4
Abeliovich, A.5
-
120
-
-
33747373586
-
The potentiating effects of 1-methyl-4-phe-nyl-1,2,3,6-tetrahydropyridine (MPTP) on paraquat-induced neurochemical and behavioral changes in mice
-
Shepherd KR, ES Lee, L Schmued, Y Jiao, SF Ali, ET Oriaku, NS Lamango, KF Soliman and CG Charlton (2006) The potentiating effects of 1-methyl-4-phe-nyl-1,2,3,6-tetrahydropyridine (MPTP) on paraquat-induced neurochemical and behavioral changes in mice. Pharmacol. Biochem. Behav. 83(3), 349-359.
-
(2006)
Pharmacol. Biochem. Behav.
, vol.83
, Issue.3
, pp. 349-359
-
-
Shepherd, K.R.1
Lee, E.S.2
Schmued, L.3
Jiao, Y.4
Ali, S.F.5
Oriaku, E.T.6
Lamango, N.S.7
Soliman, K.F.8
Charlton, C.G.9
-
121
-
-
0037229425
-
Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation
-
Sherer TB, JH Kim, R Betarbet and JT Greenamyre (2003) Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation. Exp. Neurol. 179(1), 9-16.
-
(2003)
Exp. Neurol.
, vol.179
, Issue.1
, pp. 9-16
-
-
Sherer, T.B.1
Kim, J.H.2
Betarbet, R.3
Greenamyre, J.T.4
-
122
-
-
0035816365
-
Carrier-mediated processes in blood-brain barrier penetration and neural uptake of paraquat
-
Shimizu K, K Ohtaki, K Matsubara, K Aoyama, T Uezono, O Saito, M Suno, K Ogawa, N Hayase, K Kimura and H Shiono (2001) Carrier-mediated processes in blood-brain barrier penetration and neural uptake of paraquat. Brain Res. 906 (1-2), 135-142.
-
(2001)
Brain Res.
, vol.906
, Issue.1-2
, pp. 135-142
-
-
Shimizu, K.1
Ohtaki, K.2
Matsubara, K.3
Aoyama, K.4
Uezono, T.5
Saito, O.6
Suno, M.7
Ogawa, K.8
Hayase, N.9
Kimura, K.10
Shiono, H.11
-
123
-
-
0242300619
-
α-Synuclein locus triplication causes Parkinson's disease
-
Singleton AB, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, M Hulihan, T Peuralinna, A Dutra, R Nussbaum, S Lincoln, A Crawley, M Hanson, D Maraganore, C Adler, MR Cookson, M Muenter, M Baptista, D Miller, J Blancato, J Hardy and K Gwinn-Hardy (2003) α-Synuclein locus triplication causes Parkinson's disease. Science 302(5646), 841.
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
124
-
-
1542617769
-
Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP
-
Song DD, CW Shults, A Sisk, E Rockenstein and E Masliah (2004) Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP. Exp. Neurol. 186(2), 158-172.
-
(2004)
Exp. Neurol.
, vol.186
, Issue.2
, pp. 158-172
-
-
Song, D.D.1
Shults, C.W.2
Sisk, A.3
Rockenstein, E.4
Masliah, E.5
-
125
-
-
0032568534
-
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini MG, RA Crowther, R Jakes, M Hasegawa and M Goedert (1998) α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc. Natl. Acad. Sci. USA 95(11), 6469-6473.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.11
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
126
-
-
0035097503
-
Clinical and pathological features of a Parkinsonian syndrome in a family with an Ala53Thr alpha-synuclein mutation
-
Spira PJ, DM Sharpe, G Halliday, J Cavanagh and GA Nicholson (2001) Clinical and pathological features of a Parkinsonian syndrome in a family with an Ala53Thr alpha-synuclein mutation. Ann. Neurol. 49(3), 313-319.
-
(2001)
Ann. Neurol.
, vol.49
, Issue.3
, pp. 313-319
-
-
Spira, P.J.1
Sharpe, D.M.2
Halliday, G.3
Cavanagh, J.4
Nicholson, G.A.5
-
127
-
-
1642527499
-
DJ-1 has a role in antioxidative stress to prevent cell death
-
Taira T, Y Saito, T Niki, SM Iguchi-Ariga, K Takahashi and H Ariga (2004) DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep. 5(2), 213-218.
-
(2004)
EMBO Rep.
, vol.5
, Issue.2
, pp. 213-218
-
-
Taira, T.1
Saito, Y.2
Niki, T.3
Iguchi-Ariga, S.M.4
Takahashi, K.5
Ariga, H.6
-
128
-
-
0034624274
-
Increased striatal dopamine turnover following acute administration of rotenone to mice
-
Thiffault C, JW Langston and DA Di Monte (2000) Increased striatal dopamine turnover following acute administration of rotenone to mice. Brain Res. 885, 283-288.
-
(2000)
Brain Res.
, vol.885
, pp. 283-288
-
-
Thiffault, C.1
Langston, J.W.2
Di Monte, D.A.3
-
129
-
-
0042421940
-
Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype
-
Thiruchelvam M, A McCormack, EK Richfield, RB Baggs, AW Tank, DA Di Monte and DA Cory-Slechta (2003) Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype. Eur. J. Neurosci. 18(3), 589-600.
-
(2003)
Eur. J. Neurosci.
, vol.18
, Issue.3
, pp. 589-600
-
-
Thiruchelvam, M.1
McCormack, A.2
Richfield, E.K.3
Baggs, R.B.4
Tank, A.W.5
Di Monte, D.A.6
Cory-Slechta, D.A.7
-
130
-
-
0034671469
-
The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb, implications for Parkinson's disease
-
Thiruchelvam M, EK Richfield, RB Baggs, AW Tank and DA Cory-Slechta (2000) The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb, implications for Parkinson's disease. J. Neurosci. 20(24), 9207-9214.
-
(2000)
J. Neurosci.
, vol.20
, Issue.24
, pp. 9207-9214
-
-
Thiruchelvam, M.1
Richfield, E.K.2
Baggs, R.B.3
Tank, A.W.4
Cory-Slechta, D.A.5
-
131
-
-
1542359628
-
Risk factors for dopaminergic neuron loss in human alpha-synuclein transgenic mice
-
Thiruchelvam MJ, JM Powers, DA Cory-Slechta and EK Richfield (2004) Risk factors for dopaminergic neuron loss in human alpha-synuclein transgenic mice. Eur. J. Neurosci. 19(4), 845-854.
-
(2004)
Eur. J. Neurosci.
, vol.19
, Issue.4
, pp. 845-854
-
-
Thiruchelvam, M.J.1
Powers, J.M.2
Cory-Slechta, D.A.3
Richfield, E.K.4
-
132
-
-
33646097224
-
Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120), implications for Lewy body disorders
-
Tofaris GK, P Garcia Reitbock, T Humby, SL Lambourne, M O'Connell, B Ghetti, H Gossage, PC Emson, LS Wilkinson, M Goedert and MG Spillantini (2006) Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120), implications for Lewy body disorders. J. Neurosci. 26(15), 3942-3950.
-
(2006)
J. Neurosci.
, vol.26
, Issue.15
, pp. 3942-3950
-
-
Tofaris, G.K.1
Garcia Reitbock, P.2
Humby, T.3
Lambourne, S.L.4
O'Connell, M.5
Ghetti, B.6
Gossage, H.7
Emson, P.C.8
Wilkinson, L.S.9
Goedert, M.10
Spillantini, M.G.11
-
133
-
-
4444274910
-
PINK1 mutations are associated with sporadic early-onset parkinsonism
-
Valente EM, S Salvi, T Ialongo, R Marongiu, AE Elia, V Caputo, L Romito, A Albanese, B Dallapiccola and AR Bentivoglio (2004) PINK1 mutations are associated with sporadic early-onset parkinsonism. Ann. Neurol. 56(3), 336-341.
-
(2004)
Ann. Neurol.
, vol.56
, Issue.3
, pp. 336-341
-
-
Valente, E.M.1
Salvi, S.2
Ialongo, T.3
Marongiu, R.4
Elia, A.E.5
Caputo, V.6
Romito, L.7
Albanese, A.8
Dallapiccola, B.9
Bentivoglio, A.R.10
-
134
-
-
0034663176
-
Neuropathology in mice expressing human alpha-synuclein
-
van der Putten H, KH Wiederhold, A Probst, S Barbieri, C Mistl, S Danner, S Kauffmann, K Hofele, WP Spooren, MA Ruegg, S Lin, P Caroni, B Sommer, M Tolnay and G Bilbe (2000) Neuropathology in mice expressing human alpha-synuclein. J. Neurosci. 20(16), 6021-6029.
-
(2000)
J. Neurosci.
, vol.20
, Issue.16
, pp. 6021-6029
-
-
van der Putten, H.1
Wiederhold, K.H.2
Probst, A.3
Barbieri, S.4
Mistl, C.5
Danner, S.6
Kauffmann, S.7
Hofele, K.8
Spooren, W.P.9
Ruegg, M.A.10
Lin, S.11
Caroni, P.12
Sommer, B.13
Tolnay, M.14
Bilbe, G.15
-
135
-
-
0033966487
-
Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP
-
Vila M, S Vukosavic, V Jackson-Lewis, M Neystat, M Jakowec and S Przedborski (2000) Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP. J. Neurochem. 74(2), 721-729.
-
(2000)
J. Neurochem.
, vol.74
, Issue.2
, pp. 721-729
-
-
Vila, M.1
Vukosavic, S.2
Jackson-Lewis, V.3
Neystat, M.4
Jakowec, M.5
Przedborski, S.6
-
136
-
-
3242677684
-
Loss of locus coeruleus neurons and reduced startle in parkin null mice
-
Von Coelln R, B Thomas, JM Savitt, KL Lim, M Sasaki, EJ Hess, VL Dawson and TM Dawson (2004) Loss of locus coeruleus neurons and reduced startle in parkin null mice. Proc. Natl. Acad. Sci. USA 101(29), 10744-10749.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.29
, pp. 10744-10749
-
-
Von Coelln, R.1
Thomas, B.2
Savitt, J.M.3
Lim, K.L.4
Sasaki, M.5
Hess, E.J.6
Dawson, V.L.7
Dawson, T.M.8
-
137
-
-
34249789325
-
Selective loss of nigral dopamine neurons induced by over-expression of truncated human α-synuclein in mice
-
Dec 13; [Epub ahead of print]
-
Wakamatsu M, A Ishii, S Iwata, J Sakagami, Y Ukai, M Ono, D Kanbe, SL Muramatsu, K Kobayashi, T Iwatsubo and M Yoshimoto (2006) Selective loss of nigral dopamine neurons induced by over-expression of truncated human α-synuclein in mice. Neurobiol Aging 2006 Dec 13; [Epub ahead of print]
-
(2006)
Neurobiol Aging
, vol.2006
-
-
Wakamatsu, M.1
Ishii, A.2
Iwata, S.3
Sakagami, J.4
Ukai, Y.5
Ono, M.6
Kanbe, D.7
Muramatsu, S.L.8
Kobayashi, K.9
Iwatsubo, T.10
Yoshimoto, M.11
-
138
-
-
0033062725
-
Diethyldithiocarbamate causes nigral cell loss and dopamine depletion with nontoxic doses of MPTP
-
Walters TL, I Irwin, K Delfani, JW Langston and AM Janson (1999) Diethyldithiocarbamate causes nigral cell loss and dopamine depletion with nontoxic doses of MPTP. Exp. Neurol. 156(1), 62-70.
-
(1999)
Exp. Neurol.
, vol.156
, Issue.1
, pp. 62-70
-
-
Walters, T.L.1
Irwin, I.2
Delfani, K.3
Langston, J.W.4
Janson, A.M.5
-
139
-
-
0029739461
-
No changes in behaviour, nigro-striatal system neurochemistry or neuronal cell death following toxic multiple oral paraquat administration to rats
-
Widdowson PS, MJ Farnworth, R Upton and MG Simpson (1996) No changes in behaviour, nigro-striatal system neurochemistry or neuronal cell death following toxic multiple oral paraquat administration to rats. Hum. Exp. Toxicol. 15, 583-591.
-
(1996)
Hum. Exp. Toxicol.
, vol.15
, pp. 583-591
-
-
Widdowson, P.S.1
Farnworth, M.J.2
Upton, R.3
Simpson, M.G.4
-
140
-
-
0034647948
-
Mutation analysis and association studies of the UCHL1 gene in German Parkinson's disease patients
-
Wintermeyer P, R Kruger, W Kuhn, T Muller, D Woitalla, D Berg, G Becker, E Leroy, M Polymeropoulos, K Berger, H Przuntek, L Schols, JT Epplen and O Riess (2000) Mutation analysis and association studies of the UCHL1 gene in German Parkinson's disease patients. Neuroreport 11(10), 2079-2082.
-
(2000)
Neuroreport
, vol.11
, Issue.10
, pp. 2079-2082
-
-
Wintermeyer, P.1
Kruger, R.2
Kuhn, W.3
Muller, T.4
Woitalla, D.5
Berg, D.6
Becker7
-
141
-
-
20944437573
-
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
-
Xu J, N Zhong, H Wang, JE Elias, CY Kim, I Woldman, C Pifl, SP Gygi, C Geula and BA Yankner (2005) The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Hum. Mol. Genet. 14(9), 1231-1241.
-
(2005)
Hum. Mol. Genet.
, vol.14
, Issue.9
, pp. 1231-1241
-
-
Xu, J.1
Zhong, N.2
Wang, H.3
Elias, J.E.4
Kim, C.Y.5
Woldman, I.6
Pifl, C.7
Gygi, S.P.8
Geula, C.9
Yankner, B.A.10
-
142
-
-
14544288232
-
Therapeutic potential of adenosine A(2A) receptor antagonists in Parkinson's disease
-
Xu K, E Bastia and M Schwarzschild (2005) Therapeutic potential of adenosine A(2A) receptor antagonists in Parkinson's disease. Pharmacol. Ther. 105(3), 267-310.
-
(2005)
Pharmacol. Ther.
, vol.105
, Issue.3
, pp. 267-310
-
-
Xu, K.1
Bastia, E.2
Schwarzschild, M.3
-
143
-
-
0026544129
-
Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease
-
Yoshino H, Y Nakagawa-Hattori, T Kondo and Y Mizuno (1992) Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease. J. Neural Transm. Park. Dis. Dement. Sect. 4(1), 27-34.
-
(1992)
J. Neural Transm. Park. Dis. Dement. Sect.
, vol.4
, Issue.1
, pp. 27-34
-
-
Yoshino, H.1
Nakagawa-Hattori, Y.2
Kondo, T.3
Mizuno, Y.4
-
144
-
-
0027329926
-
The role of iron in senescence of dopaminergic neurons in Parkinson's disease
-
Youdim MB and P Riederer (1993) The role of iron in senescence of dopaminergic neurons in Parkinson's disease. J. Neural Transm. Suppl. 40, 57-67.
-
(1993)
J. Neural Transm. Suppl.
, vol.40
, pp. 57-67
-
-
Youdim, M.B.1
Riederer, P.2
-
145
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz JJ, J Alegre, JC Gomez-Esteban, E Lezcano, R Ros, I Ampuero, L Vidal, J Hoenicka, O Rodriguez, B Atares, V Llorens, E Gomez Tortosa, T del Ser, DG Munoz and JG de Yebenes (2004) The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann. Neurol. 55(2), 164-173.
-
(2004)
Ann. Neurol.
, vol.55
, Issue.2
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
Llorens, V.11
Gomez Tortosa, E.12
del Ser, T.13
Munoz, D.G.14
de Yebenes, J.G.15
-
146
-
-
17144379764
-
The tau gene haplotype h1 confers a susceptibility to Parkinson's disease
-
Zhang J, Y Song, H Chen and D Fan (2005) The tau gene haplotype h1 confers a susceptibility to Parkinson's disease. Eur. Neurol. 53(1), 15-21.
-
(2005)
Eur. Neurol.
, vol.53
, Issue.1
, pp. 15-21
-
-
Zhang, J.1
Song, Y.2
Chen, H.3
Fan, D.4
-
147
-
-
20144389524
-
Aggregated alpha-synuclein activates microglia, a process leading to disease progression in Parkinson's disease
-
Zhang W, T Wang, Z Pei, DS Miller X Wu, ML Block, B Wilson, W Zhang, Y Zhou, JS Hong and J Zhang (2005) Aggregated alpha-synuclein activates microglia, a process leading to disease progression in Parkinson's disease. FASEB J. 19(6), 533-542.
-
(2005)
FASEB J.
, vol.19
, Issue.6
, pp. 533-542
-
-
Zhang, W.1
Wang, T.2
Pei, Z.3
Miller, D.S.4
Wu, X.5
Block, M.L.6
Wilson, B.7
Zhang, W.8
Zhou, Y.9
Hong, J.S.10
Zhang, J.11
-
148
-
-
30044449754
-
DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity
-
Zhou W and CR Freed (2005) DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity. J. Biol. Chem. 280(52), 43150-43158.
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.52
, pp. 43150-43158
-
-
Zhou, W.1
Freed, C.R.2
-
149
-
-
31344464179
-
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
-
Zhou W, M Zhu, MA Wilson, GA Petsko and AL Fink (2006) The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein. J. Mol. Biol. 356(4), 1036-1048.
-
(2006)
J. Mol. Biol.
, vol.356
, Issue.4
, pp. 1036-1048
-
-
Zhou, W.1
Zhu, M.2
Wilson, M.A.3
Petsko, G.A.4
Fink, A.L.5
-
150
-
-
4644263680
-
Variable effects of chronic subcutaneous administration of rote-none on striatal histology
-
Zhu C, P Vourc'h, PO Fernagut, SM Fleming, S Lacan, CD Dicarlo, RL Seaman and MF Chesselet (2004) Variable effects of chronic subcutaneous administration of rote-none on striatal histology. J. Comp. Neurol. 478(4), 418-426.
-
(2004)
J. Comp. Neurol.
, vol.478
, Issue.4
, pp. 418-426
-
-
Zhu, C.1
Vourc'h, P.2
Fernagut, P.O.3
Fleming, S.M.4
Lacan, S.5
Dicarlo, C.D.6
Seaman, R.L.7
Chesselet, M.F.8
-
151
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
Zimprich A, S Biskup, P Leitner, P Lichtner, M Farrer, S Lincoln, J Kachergus, M Hulihan, RJ Uitti, DB Calne, AJ Stoessl, RF Pfeiffer, N Patenge, IC Carbajal, P Vieregge, F Asmus, B Muller-Myhsok, DW Dickson, T Meitinger, TM Strom, ZK Wszolek and T Gasser (2004) Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44(4), 601-607.
-
(2004)
Neuron
, vol.44
, Issue.4
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
Stoessl, A.J.11
Pfeiffer, R.F.12
Patenge, N.13
Carbajal, I.C.14
Vieregge, P.15
Asmus, F.16
Muller-Myhsok, B.17
Dickson, D.W.18
Meitinger, T.19
Strom, T.M.20
Wszolek, Z.K.21
Gasser, T.22
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