Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra

Brain Research

Volumn 753, Issue 1, 1997, Pages 157-162

  Ferrante, Robert J ^a,b   Schulz, Jörg B ^c,e   Kowall, Neil W ^a,b   Beal, M Flint ^d  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Department of Neurology ^*  (Germany)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine (MPTP); basal ganglion; complex I; mitochondrion; NADPH diaphorase; Parkinson's; substantia nigra

Indexed keywords

ROTENONE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN INJURY; CENTRAL NERVOUS SYSTEM; CORPUS STRIATUM; GLOBUS PALLIDUS; IMMUNOCYTOCHEMISTRY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA;

ANIMALS; CORPUS STRIATUM; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GLOBUS PALLIDUS; INFUSION PUMPS, IMPLANTABLE; INSECTICIDES; MALE; NAD(P)H DEHYDROGENASE (QUINONE); NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; ROTENONE; SUBSTANTIA NIGRA;

EID: 0031005815     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00008-5     Document Type: Article

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