Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

GLIA

Volumn 55, Issue 5, 2007, Pages 453-462

  Qin, Liya ^a   Wu, Xuefei ^b   Block, Michelle L ^c   Liu, Yuxin ^a,c   Breese, George R ^a   Hong, Jau Shyong ^c   Knapp, Darin J ^a   Crews, Fulton T ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

LPS; Microglia; Neurodegeneration; Neuroinflammation; Substantia nigra; TNF

Indexed keywords

INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL LOSS; CHRONIC INFLAMMATION; CONTROLLED STUDY; DISEASE COURSE; DOPAMINERGIC NERVE CELL; ENCEPHALITIS; HISTOPATHOLOGY; LIVER LEVEL; MICROGLIA; MOUSE; NERVE DEGENERATION; NEUROINFLAMMATION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SUBSTANTIA NIGRA; WILD TYPE;

ANIMALS; BRAIN; CELL DEATH; DISEASE MODELS, ANIMAL; DOPAMINE; INFLAMMATION; INFLAMMATION MEDIATORS; INJECTIONS, INTRAPERITONEAL; LIPOPOLYSACCHARIDES; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MICROGLIA; NEURODEGENERATIVE DISEASES; NEURONS; PARKINSON DISEASE; RNA, MESSENGER; SUBSTANTIA NIGRA; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33847759064     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20467     Document Type: Article

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