Cytoplasmic domain of the β-amyloid protein precursor of Alzheimer's disease: Function, regulation of proteolysis, and implications for drug development

Journal of Neuroscience Research

Volumn 80, Issue 2, 2005, Pages 151-159

  Kerr, Megan L ^a   Small, David H ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

amyloid; secretase; 20S proteasome; Adaptor protein; Alzheimer's disease; Amyloid protein precursor

Indexed keywords

A DISINTEGRIN AND METALLOPROTEASE 10; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GAMMA SECRETASE; METALLOPROTEINASE; PROTEASOME; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; DRUG TARGETING; HUMAN; NEUROPATHOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SHORT SURVEY;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CYTOPLASM; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PROTEIN TRANSPORT;

EID: 18744405422     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20408     Document Type: Short Survey

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