Neurotoxicity and physicochemical properties of Aβ mutant peptides from cerebral amyloid angiopathy: Implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease

Journal of Biological Chemistry

Volumn 278, Issue 46, 2003, Pages 46179-46187

  Murakami, Kazuma ^a   Irie, Kazuhiro ^a   Morimoto, Akira ^a   Ohigashi, Hajime ^a   Shindo, Mayumi ^b   Nagao, Masaya ^a   Shimizu, Takahiko ^c   Shirasawa, Takuji ^c  

^a KYOTO UNIVERSITY   (Japan)

^b Applied Biosystems Japan Ltd   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; FOURIER TRANSFORM INFRARED SPECTROSCOPY; MUTAGENESIS; PATHOLOGY; TOXICITY;

CEREBRAL HEMORRHAGE; PHYSICOCHEMICAL PROPERTIES;

POLYPEPTIDES;

AMYLOID BETA PROTEIN; MUTANT PROTEIN; PEPTIDE DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NEUROTOXICITY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; VASCULAR AMYLOIDOSIS;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; AMYLOIDOSIS; ANIMALS; COLORING AGENTS; HUMANS; HYDROGEN BONDING; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PC12 CELLS; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS;

ANIMALIA;

EID: 0242580170     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301874200     Document Type: Article

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